Honorary Professor

Kum Kum Khanna

Email: 

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis

Search Professor Kum Kum Khanna’s works on UQ eSpace

197 works between 1995 and 2025
All (197) Journal Article (184) Conference Publication (11) Other Outputs (2)

61 - 80 of 197 works

2015

Conference Publication

SSB1 AND SSB2 SINGLE-STRANDED DNA BINDING PROTEINS ARE ESSENTIAL FOR HSC FUNCTION

Vu, Therese, Shi, Wei, Lane, Steven and Khanna, Kum Kum (2015). SSB1 AND SSB2 SINGLE-STRANDED DNA BINDING PROTEINS ARE ESSENTIAL FOR HSC FUNCTION. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto Japan, Sep 17-19, 2015. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.exphem.2015.06.274

SSB1 AND SSB2 SINGLE-STRANDED DNA BINDING PROTEINS ARE ESSENTIAL FOR HSC FUNCTION

2015

Journal Article

Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice

Boucher, Didier, Vu, Therese, Bain, Amanda L., Tagliaro-Jahns, Marina, Shi, Wei, Lane, Steven W. and Khanna, Kum Kum (2015). Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice. FASEB Journal, 29 (8), 3326-3334. doi: 10.1096/fj.14-269944

Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice

2015

Journal Article

Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer

Liu, Chao, Srihari, Sriganesh, Lal, Samir, Gautier, Benoit, Simpson, Peter T., Khanna, Kum Kum, Ragan, Mark A. and LeCao, Kim-Anh (2015). Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer. Molecular Oncology, 10 (1), 179-193. doi: 10.1016/j.molonc.2015.09.007

Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer

2015

Journal Article

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib

Bessette, Darrell C., Tilch, Erik, Seidens, Tatjana, Quinn, Michael C. J., Wiegmans, Adrian P., Shi, Wei, Cocciardi, Sibylle, McCart-Reed, Amy, Saunus, Jodi M., Simpson, Peter T., Grimmond, Sean M., Lakhani, Sunil R., Khanna, Kum Kum, Waddell, Nic, Al-Ejeh, Fares and Chevenvix-Trench, Georgia (2015). Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib. PLoS One, 10 (5) e0125232, e0125232-e0125232. doi: 10.1371/journal.pone.0125232

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib

2015

Conference Publication

The adaptor protein ASC controls transplantation outcomes independently of the inflammasome

Cheong, Melody, Gartlan, Kate, Tey, Siok-Keen, Kuns, Rachel, Lor, Mary, Lineburg, Katie, Tea, Bianca, Shi, Wei, Raju, Jyothy, Zhang, Ping, Varelias, Antiopi, Leveque-El Mouttie, Lucie, Olver, Stuart, Bunting, Mark, Lane, Steven, Boyle, Glen, Ting, Jenny, Schroder, Kate, Engwerda, Christian, Khanna, Kum Kum, Smyth, Mark, MacDonald, Kelli, Koyama, Motoko and Hill, Geoffrey (2015). The adaptor protein ASC controls transplantation outcomes independently of the inflammasome. Annual Meeting of the American-Association-of-Immunologists (IMMUNOLOGY), New Orleans La, May 08-12, 2015. BETHESDA: AMER ASSOC IMMUNOLOGISTS.

The adaptor protein ASC controls transplantation outcomes independently of the inflammasome

2015

Journal Article

Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish

Jeffery, Jessie, Neyt, Christine, Moore, Wade, Paterson, Scott, Bower, Neil I., Chenevix-Trench, Georgia, Verkade, Heather, Hogan, Benjamin M. and Khanna, Kum Kum (2015). Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish. The FASEB Journal, 29 (5), 1999-2009. doi: 10.1096/fj.14-265090

Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish

2015

Journal Article

Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis

Jeffery, J., Sinha, D., Srihari, S., Kalimutho, M. and Khanna, K. K. (2015). Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis. Oncogene, 35 (6), 683-690. doi: 10.1038/onc.2015.128

Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis

2015

Journal Article

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

Kalousi, Alkmini, Hoffbeck, Anne-Sophie, Selemenakis, Platonas N., Pinder, Jordan, Savage, Kienan I., Khanna, Kum Kum, Brino, Laurent, Dellaire, Graham, Gorgoulis, Vassilis G. and Soutoglou, Evi (2015). The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin. Cell Reports, 11 (1), 149-163. doi: 10.1016/j.celrep.2015.03.005

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

2015

Journal Article

The Integrator complex controls the termination of transcription at diverse classes of gene targets

Skaar, Jeffrey R., Ferris, Andrea L., Wu, Xiaolin, Saraf, Anita, Khanna, Kum Kum, Florens, Laurence, Washburn, Michael P., Hughes, Stephen H. and Pagano, Michele (2015). The Integrator complex controls the termination of transcription at diverse classes of gene targets. Cell Research, 25 (3), 288-305. doi: 10.1038/cr.2015.19

The Integrator complex controls the termination of transcription at diverse classes of gene targets

2015

Journal Article

Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs

Pandita, Raj K., Chow, Tracy T., Udayakumar, Durga, Bain, Amanda L., Cubeddu, Liza, Hunt, Clayton R., Shi, Wei, Horikoshi, Nobuo, Zhao, Yong, Wright, Woodring E., Khanna, Kum Kum, Shay, Jerry W. and Pandita, Tej K. (2015). Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs. Cancer Research, 75 (5), 858-869. doi: 10.1158/0008-5472.CAN-14-2289

Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs

2015

Journal Article

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines

Momeny, Majid, Saunus, Jodi M., Marturana, Flavia, McCart Reed, Amy E., Black, Debra, Sala, Gianluca, Iacobelli, Stefano, Holland, Jane D., Yu, Dihua, Da Silva, Leonard, Simpson, Peter T., Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2015). Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget, 6 (6), 3932-3946. doi: 10.18632/oncotarget.2846

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines

2015

Conference Publication

Genomic and transcriptomic landscapes of human brain metastases

Saunus, J. M., Quinn, M. C. J., Patch, A. M., Pearson, J. V., Bailey, P. J., Cloonan, N., Nones, K., Miller, D., Mariasegaram, M., Lau, Q., Jeffree, L., Khanna, K. K., Chenevix-Trench, G., Grimmond, S. M., Simpson, P. T., Waddell, N. and Lakhani, S. R. (2015). Genomic and transcriptomic landscapes of human brain metastases. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

Genomic and transcriptomic landscapes of human brain metastases

2015

Journal Article

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

Kijas, Amanda W., Lim, Yi Chieh, Bolderson, Emma, Cerosaletti, Karen, Gatei, Magtouf, Jakob, Burkhard, Tobias, Frank, Taucher-Scholz, Gisela, Gueven, Nuri, Oakley, Greg, Concannon, Patrick, Wolvetang, Ernst, Khanna, Kum Kum, Wiesmuller, Lisa and Lavin, Martin F. (2015). ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Research, 43 (17), 8352-8367. doi: 10.1093/nar/gkv754

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

2014

Journal Article

Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma

de Andrade, Lucas Ferrari, Ngiow, Shin F., Stannard, Kimberly, Rusakiewicz, Sylvie, Kalimutho, Murugan, Khanna, Kum Kum, Tey, Siok-Keen, Takeda, Kazyuoshi, Zitvogel, Laurence, Martinet, Ludovic and Smyth, Mark J. (2014). Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Research, 74 (24), 7298-7308. doi: 10.1158/0008-5472.CAN-14-1339

Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma

2014

Journal Article

Complex-based analysis of dysregulated cellular processes in cancer

Srihari, Sriganesh, Madhamshettiwar, Piyush B., Song, Sarah, Liu, Chao, Simpson, Peter T., Khanna, Kumkum and Ragan, Mark A. (2014). Complex-based analysis of dysregulated cellular processes in cancer. BMC Systems Biology, 8 (Supplement 4) S1. doi: 10.1186/1752-0509-8-S4-S1

Complex-based analysis of dysregulated cellular processes in cancer

2014

Journal Article

SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G 2 phase of cell cycle to prevent Re-replication

Johansson, Pegah, Jeffery, Jessie, Al-Ejeh, Fares, Schulz, Renèe B., Callen, David F., Kumar, Raman and Khanna, Kum Kum (2014). SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G 2 phase of cell cycle to prevent Re-replication. Journal of Biological Chemistry, 289 (26), 18514-18525. doi: 10.1074/jbc.M114.559930

SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G 2 phase of cell cycle to prevent Re-replication

2014

Journal Article

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma

Al-Ejeh, Fares, Pajic, Marina, Shi, Wei, Kalimutho, Murugan, Miranda, Mariska, Nagrial, Adnan M., Chou, Angela, Biankin, Andrew V., Grimmond, Sean M., Brown, Michael P. and Khanna, Kum Kum (2014). Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma. Clinical Cancer Research, 20 (12), 3187-3197. doi: 10.1158/1078-0432.CCR-14-0048

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma

2014

Journal Article

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks

Bolderson, Emma, Petermann, Eva, Croft, Laura, Suraweera, Amila, Pandita, Raj K., Pandita, Tej K., Helleday, Thomas, Khanna, Kum Kum and Richard, Derek J. (2014). Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks. Nucleic Acids Research, 42 (10), 6326-6336. doi: 10.1093/nar/gku276

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks

2014

Journal Article

A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy

Liu, Chao, Srihari, Sriganesh, Le Cao, Kim-Anh, Chenevix-Trench, Georgia, Simpson, Peter T., Ragan, Mark A. and Khanna, Kum Kum (2014). A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy. Nucleic Acids Research, 42 (10), 6106-6127. doi: 10.1093/nar/gku284

A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy

2014

Journal Article

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Al-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Current funding

  • 2024 - 2025
    Targeting the redox niche in triple-negative breast cancer to treat brain metastases
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2024 - 2027
    Targeting metstatic breast cancer by oligonucleotide therapeutics with the FDA lipid nanoparticles (LNP) delivery system.
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2022 - 2025
    Targeting CEP55 in Triple-Negative Breast Cancer (US DoD CDMRP grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2024
    Exploitation of immunogenicity of Cep 55 to enhance efficacy of therapy for triple-negative breast cancer
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Optimising systemic therapies of metastatic and recurrent triple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Understanding novel regulators of mitosis and their implication in cancer

    Principal Advisor

  • Doctor Philosophy

    Understanding novel regulators of mitosis and their implication in cancer

    Principal Advisor

  • Doctor Philosophy

    Functional validation of therapeutic targets for basal breast cancer

    Principal Advisor

  • Doctor Philosophy

    Optimising systemic therapies of metastatic and recurrent triple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Investigating the diagnostic and functional significance of specific epigenomic features in triple-negative breast cancer (TNBC)

    Associate Advisor

    Other advisors: Dr Jodi Saunus

  • Doctor Philosophy

    Breaking barriers: unlocking the potential of cytomegalovirus-specific T cells in allogeneic CAR T cell therapies

    Associate Advisor

  • Doctor Philosophy

    Designing Therapeutic Strategies Targeting KRAS

    Associate Advisor

Completed supervision

Enquiries

For media enquiries about Honorary Professor Kum Kum Khanna's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au