Honorary Professor

Kum Kum Khanna

Email: 

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis

Search Professor Kum Kum Khanna’s works on UQ eSpace

197 works between 1995 and 2025
All (197) Journal Article (184) Conference Publication (11) Other Outputs (2)

81 - 100 of 197 works

2014

Journal Article

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

Tomimatsu, Nozomi, Mukherjee, Bipasha, Catherine Hardebeck, Molly, Ilcheva, Mariya, Vanessa Camacho, Cristel, Louise Harris, Janelle, Porteus, Matthew, Llorente, Bertrand, Khanna, Kum K.um and Burma, Sandeep (2014). Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice. Nature communications, 5 3561. doi: 10.1038/ncomms4561

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

2014

Journal Article

Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells

Speckmann, Bodo, Gerloff, Kirsten, Simms, Lisa, Oancea, Iulia, Shi, Wei, McGuckin, Michael A., Radford-Smith, Graham and Khanna, Kum Kum (2014). Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells. Free Radical Biology and Medicine, 67, 265-277. doi: 10.1016/j.freeradbiomed.2013.11.001

Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells

2014

Journal Article

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

Al-Ejeh, Fares, Miranda, Mariska, Shi,Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2014). Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer. Oncotarget, 5 (10), 3145-3158. doi: 10.18632/oncotarget.1865

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

2014

Journal Article

Rad51 supports triple negative breast cancer metastasis

Wiegmans, Adrian P., Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J., Da Silva, Leonard, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T., Lakhani, Sunil R. and Khanna, Kum Kum (2014). Rad51 supports triple negative breast cancer metastasis. Oncotarget, 5 (10), 3261-3272. doi: 10.18632/oncotarget.1923

Rad51 supports triple negative breast cancer metastasis

2013

Journal Article

Tumor protein D52 represents a negative regulator of ATM protein levels

Chen, Yuyan, Kamili, Alvin, Hardy, Jayne R., Groblewski, Guy E., Khanna, Kum Kum and Byrne, Jennifer A. (2013). Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle, 12 (18), 3083-3097. doi: 10.4161/cc.26146

Tumor protein D52 represents a negative regulator of ATM protein levels

2013

Journal Article

Mouse models uncap novel roles of SSBs

Bain, Amanda L., Shi, Wei and Khanna, Kum Kum (2013). Mouse models uncap novel roles of SSBs. Cell Research, 23 (6), 744-745. doi: 10.1038/cr.2013.63

Mouse models uncap novel roles of SSBs

2013

Journal Article

Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor

Al-Ejeh, Fares, Shi, Wei, Miranda, Mariska, Simpson, Peter T., Vargas, Ana Cristina, Song, Sarah, Wiegmans, Adrian P., Swarbrick, Alex, Welm, Alana L., Brown, Michael P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2013). Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor. Journal of Nuclear Medicine, 54 (6), 913-921. doi: 10.2967/jnumed.112.111534

Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor

2013

Journal Article

Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment

Jeffery, Jessie M., Grigoriev, Ilya, Poser, Ina, van der Horst, Armando, Hamilton, Nicholas, Waterhouse, Nigel, Bleier, Jonathan, Subramaniam, V. Nathan, Maly, Ivan V., Akhmanova, Anna and Khanna, Kum Kum (2013). Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment. Cell Cycle, 12 (6), 899-906. doi: 10.4161/cc.23879

Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment

2013

Journal Article

Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest

Singh, Mayank, Hunt, Clayton, Pandita, Raj K., Kumar, Rakesh, Yang, Chin-Rang, Horikoshi, Nobuo, Bachoo, Robert, Serag, Sara, Story, Michael D., Shay, Jerry W., Powell, Simon N., Gupta, Arun, Jeffery, Jessie, Pandita, Shruti, Chen, Benjamin P.C., Deckbar, Dorothee, Löbrich, Markus, Yang, Qin, Khanna, Kum Kum, Worman, Howard J. and Panditaa, Tej K. (2013). Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest. Molecular and Cellular Biology, 33 (6), 1210-1222. doi: 10.1128/MCB.01676-12

Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest

2013

Journal Article

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2

Shi, Wei, Bain, Amanda L., Schwer, Bjoern, Al-Ejeh, Fares, Smith, Corey, Wong, Lee, Chai, Hua, Miranda, Mariska S., Ho, Uda, Kawaguchi, Makoto, Miura, Yutaka, Finnie, John W., Wall, Meaghan, Heierhorst, Jorg, Wicking, Carol, Spring, Kevin J., Alt, Frederick W. and Khanna, Kum Kum (2013). Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2. PLoS Genetics, 9 (2) e1003298, e1003298.1-e1003298.19. doi: 10.1371/journal.pgen.1003298

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2

2013

Journal Article

EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme

Day, Bryan W., Stringer, Brett W., Al-Ejeh, Fares, Ting, Michael J., Wilson, John, Ensbey, Kathleen S., Jamieson, Paul R., Bruce, Zara C., Lim, Yi Chieh, Offenhauser, Carolin, Charmsaz, Sara, Cooper, Leanne T., Ellacott, Jennifer K., Harding, Angus, Leveque, Lucie, Inglis, Po, Allan, Suzanne, Walker, David G., Lackmann, Martin, Osborne, Geoffrey, Khanna, Kum Kum, Reynolds, Brent A., Lickliter, Jason D. and Boyd, Andrew W. (2013). EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme. Cancer Cell, 23 (2), 238-248. doi: 10.1016/j.ccr.2013.01.007

EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme

2012

Journal Article

Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells

Chiu, Yung-Tuen, Liu, Ji, Tang, Kaidun, Wong, Yong-Chuan, Khanna, Kum Kum and Ling, Ming-Tat (2012). Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells. Plos One, 7 (12) e51108. doi: 10.1371/journal.pone.0051108

Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells

2012

Journal Article

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11

Noll, J. E., Jeffery, J., Al-Ejeh, F., Kumar, R., Khanna, K. K., Callen, D. F. and Neilsen, P. M. (2012). Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11. Oncogene, 31 (23), 2836-2848. doi: 10.1038/onc.2011.456

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11

2012

Journal Article

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

Luijsterburg, Martijn S., Acs, Klara, Ackermann, Leena, Wiegant, Wouter W., Bekker-Jensen, Simon, Larsen, Dorthe H., Khanna, Kum Kum, van Attikum, Haico, Mailand, Niels and Dantuma, Nico P. (2012). A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. Embo Journal, 31 (11), 2511-2527. doi: 10.1038/emboj.2012.104

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

2012

Conference Publication

SSB1 is essential for embryogenesis and maintenance of genomic stability in mice

Khanna, KumKum, Shi, Wei and Bain, Amanda (2012). SSB1 is essential for embryogenesis and maintenance of genomic stability in mice. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2012-2127

SSB1 is essential for embryogenesis and maintenance of genomic stability in mice

2012

Journal Article

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells

Morris, Christelle, Tomimatsu, Nozomi, Richard, Derek J., Cluet, David, Burma, Sandeep, Khanna, Kum Kum and Jalinot, Pierre (2012). INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells. Cancer Research, 72 (8), 2006-2016. doi: 10.1158/0008-5472.CAN-11-2562

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells

2012

Journal Article

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

Tomimatsu, Nozomi, Mukherjee, Bipasha, Deland, Katherine, Kurimasa, Akihiro, Bolderson, Emma, Khanna, Kum Kum and Burma, Sandeep (2012). Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions. DNA Repair, 11 (4), 441-448. doi: 10.1016/j.dnarep.2012.01.006

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

2012

Journal Article

Tocotrienol as a potential anticancer agent

Ling, Ming T., Luk, Sze U., Al-Ejeh, Fares and Khanna, Kum K. (2012). Tocotrienol as a potential anticancer agent. Carcinogenesis, 33 (2), 233-239. doi: 10.1093/carcin/bgr261

Tocotrienol as a potential anticancer agent

2012

Conference Publication

Uncovering molecular mechanisms involved in metastasis to the brain

Saunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Vargas, Ana Cristina, Al-Ejeh, Fares, Morrison, Brian, Khanna, Kum Kum, Grimmond, Sean, Chenevix-Trench, Georgia, Jeffree, Rosalind L., Waddell, Nicola, Simpson, Peter T. and Lakhani, Sunil R. (2012). Uncovering molecular mechanisms involved in metastasis to the brain. 14th International Biennial Congress of the Metastasis Research Society, Brisbane, QLD, Australia, 2-5 September 2012.

Uncovering molecular mechanisms involved in metastasis to the brain

2012

Journal Article

Potential roles for prions and protein-only inheritance in cancer

Antony, H., Wiegmans, A. P., Wei, M. Q., Chernoff, Y. O., Khanna, K. K. and Munn, A. L. (2012). Potential roles for prions and protein-only inheritance in cancer. Cancer metastasis reviews, 31 (1-2), 1-19. doi: 10.1007/s10555-011-9325-9

Potential roles for prions and protein-only inheritance in cancer

Current funding

  • 2024 - 2025
    Targeting the redox niche in triple-negative breast cancer to treat brain metastases
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2024 - 2027
    Targeting metstatic breast cancer by oligonucleotide therapeutics with the FDA lipid nanoparticles (LNP) delivery system.
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2022 - 2025
    Targeting CEP55 in Triple-Negative Breast Cancer (US DoD CDMRP grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2024
    Exploitation of immunogenicity of Cep 55 to enhance efficacy of therapy for triple-negative breast cancer
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Understanding novel regulators of mitosis and their implication in cancer

    Principal Advisor

  • Doctor Philosophy

    Functional validation of therapeutic targets for basal breast cancer

    Principal Advisor

  • Doctor Philosophy

    Optimising systemic therapies of metastatic and recurrent triple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Optimising systemic therapies of metastatic and recurrent triple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Understanding novel regulators of mitosis and their implication in cancer

    Principal Advisor

  • Doctor Philosophy

    Breaking barriers: unlocking the potential of cytomegalovirus-specific T cells in allogeneic CAR T cell therapies

    Associate Advisor

  • Doctor Philosophy

    Designing Therapeutic Strategies Targeting KRAS

    Associate Advisor

  • Doctor Philosophy

    Investigating the diagnostic and functional significance of specific epigenomic features in triple-negative breast cancer (TNBC)

    Associate Advisor

    Other advisors: Dr Jodi Saunus

Completed supervision

Enquiries

For media enquiries about Honorary Professor Kum Kum Khanna's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au