Overview
Availability
- Honorary Professor Kum Kum Khanna is:
- Available for supervision
Fields of research
Works
Search Professor Kum Kum Khanna’s works on UQ eSpace
2013
Journal Article
Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor
Al-Ejeh, Fares, Shi, Wei, Miranda, Mariska, Simpson, Peter T., Vargas, Ana Cristina, Song, Sarah, Wiegmans, Adrian P., Swarbrick, Alex, Welm, Alana L., Brown, Michael P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2013). Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor. Journal of Nuclear Medicine, 54 (6), 913-921. doi: 10.2967/jnumed.112.111534
2013
Journal Article
Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment
Jeffery, Jessie M., Grigoriev, Ilya, Poser, Ina, van der Horst, Armando, Hamilton, Nicholas, Waterhouse, Nigel, Bleier, Jonathan, Subramaniam, V. Nathan, Maly, Ivan V., Akhmanova, Anna and Khanna, Kum Kum (2013). Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment. Cell Cycle, 12 (6), 899-906. doi: 10.4161/cc.23879
2013
Journal Article
Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2
Shi, Wei, Bain, Amanda L., Schwer, Bjoern, Al-Ejeh, Fares, Smith, Corey, Wong, Lee, Chai, Hua, Miranda, Mariska S., Ho, Uda, Kawaguchi, Makoto, Miura, Yutaka, Finnie, John W., Wall, Meaghan, Heierhorst, Jorg, Wicking, Carol, Spring, Kevin J., Alt, Frederick W. and Khanna, Kum Kum (2013). Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2. PLoS Genetics, 9 (2) e1003298, e1003298.1-e1003298.19. doi: 10.1371/journal.pgen.1003298
2013
Journal Article
EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme
Day, Bryan W., Stringer, Brett W., Al-Ejeh, Fares, Ting, Michael J., Wilson, John, Ensbey, Kathleen S., Jamieson, Paul R., Bruce, Zara C., Lim, Yi Chieh, Offenhauser, Carolin, Charmsaz, Sara, Cooper, Leanne T., Ellacott, Jennifer K., Harding, Angus, Leveque, Lucie, Inglis, Po, Allan, Suzanne, Walker, David G., Lackmann, Martin, Osborne, Geoffrey, Khanna, Kum Kum, Reynolds, Brent A., Lickliter, Jason D. and Boyd, Andrew W. (2013). EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme. Cancer Cell, 23 (2), 238-248. doi: 10.1016/j.ccr.2013.01.007
2012
Journal Article
Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells
Chiu, Yung-Tuen, Liu, Ji, Tang, Kaidun, Wong, Yong-Chuan, Khanna, Kum Kum and Ling, Ming-Tat (2012). Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells. Plos One, 7 (12) ARTN e51108. doi: 10.1371/journal.pone.0051108
2012
Journal Article
Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11
Noll, J. E., Jeffery, J., Al-Ejeh, F., Kumar, R., Khanna, K. K., Callen, D. F. and Neilsen, P. M. (2012). Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11. Oncogene, 31 (23), 2836-2848. doi: 10.1038/onc.2011.456
2012
Journal Article
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
Luijsterburg, Martijn S., Acs, Klara, Ackermann, Leena, Wiegant, Wouter W., Bekker-Jensen, Simon, Larsen, Dorthe H., Khanna, Kum Kum, van Attikum, Haico, Mailand, Niels and Dantuma, Nico P. (2012). A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. Embo Journal, 31 (11), 2511-2527. doi: 10.1038/emboj.2012.104
2012
Conference Publication
SSB1 is essential for embryogenesis and maintenance of genomic stability in mice
Khanna, KumKum, Shi, Wei and Bain, Amanda (2012). SSB1 is essential for embryogenesis and maintenance of genomic stability in mice. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2012-2127
2012
Journal Article
INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells
Morris, Christelle, Tomimatsu, Nozomi, Richard, Derek J., Cluet, David, Burma, Sandeep, Khanna, Kum Kum and Jalinot, Pierre (2012). INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells. Cancer Research, 72 (8), 2006-2016. doi: 10.1158/0008-5472.CAN-11-2562
2012
Journal Article
Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions
Tomimatsu, Nozomi, Mukherjee, Bipasha, Deland, Katherine, Kurimasa, Akihiro, Bolderson, Emma, Khanna, Kum Kum and Burma, Sandeep (2012). Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions. DNA Repair, 11 (4), 441-448. doi: 10.1016/j.dnarep.2012.01.006
2012
Journal Article
Tocotrienol as a potential anticancer agent
Ling, Ming T., Luk, Sze U., Al-Ejeh, Fares and Khanna, Kum K. (2012). Tocotrienol as a potential anticancer agent. Carcinogenesis, 33 (2), 233-239. doi: 10.1093/carcin/bgr261
2012
Conference Publication
Uncovering molecular mechanisms involved in metastasis to the brain
Saunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Vargas, Ana Cristina, Al-Ejeh, Fares, Morrison, Brian, Khanna, Kum Kum, Grimmond, Sean, Chenevix-Trench, Georgia, Jeffree, Rosalind L., Waddell, Nicola, Simpson, Peter T. and Lakhani, Sunil R. (2012). Uncovering molecular mechanisms involved in metastasis to the brain. 14th International Biennial Congress of the Metastasis Research Society, Brisbane, QLD, Australia, 2-5 September 2012.
2012
Journal Article
Potential roles for prions and protein-only inheritance in cancer
Antony, H., Wiegmans, A. P., Wei, M. Q., Chernoff, Y. O., Khanna, K. K. and Munn, A. L. (2012). Potential roles for prions and protein-only inheritance in cancer. Cancer metastasis reviews, 31 (1-2), 1-19. doi: 10.1007/s10555-011-9325-9
2012
Conference Publication
Role of HER3 in brain metastases from primary breast cancer
Saunus, Jodi M., Da Silva, Leonard, Momeny, Majid, Morrison, Brian, Lane, Annette, Smart, Chanel, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2012). Role of HER3 in brain metastases from primary breast cancer. 24th Lorne Cancer Conference, Lorne, VIC, Australia, 9-12 February 2012.
2011
Journal Article
ATM protein kinase: The linchpin of cellular defenses to stress
Bhatti, Shahzad, Kozlov, Sergei, Farooqi, Ammad Ahmad, Naqi, Ali, Lavin, Martin and Khanna, Kum Kum (2011). ATM protein kinase: The linchpin of cellular defenses to stress. Cellular and Molecular Life Sciences, 68 (18), 2977-3006. doi: 10.1007/s00018-011-0683-9
2011
Journal Article
Rare variants in the ATM gene and risk of breast cancer
Goldgar, David E., Healey, Sue, Dowty, James G., Da Silva, Leonard, Chen, Xiaoqing, Spurdle, Amanda B., Terry, Mary B., Daly, Mary J., Buys, Saundra M., Southey, Melissa C., Andrulis, Irene, John, Esther M., Breast Cancer Family Registry, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Khanna, Kum K., Hopper, John L., Oefner, Peter J., Lakhani, Sunil and Chenevix-Trench, Georgia (2011). Rare variants in the ATM gene and risk of breast cancer. Breast Cancer Research, 13 (4) R73, R73-1-R73-9. doi: 10.1186/bcr2919
2011
Journal Article
Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons
Jung, Cha-Gyun, Uhm, Kyung-Ok, Miura, Yutaka, Hosono, Takashi, Horike, Hirofumi, Khanna, Kum Kum, Kim, Mi-Jeong and Michikawa, Makoto (2011). Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons. Molecular Neurodegeneration, 6 (47) 47, 1-14. doi: 10.1186/1750-1326-6-47
2011
Journal Article
hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity
Richard, Derek J., Cubeddu, Liza, Urquhart, Aaron J., Bain, Amanda, Bolderson, Emma, Menon, Dinoop, White, Malcolm F. and Khanna, Kum Kum (2011). hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity. Nucleic Acids Research, 39 (9), 3643-3651. doi: 10.1093/nar/gkq1340
2011
Journal Article
Breast cancer stem cells: Treatment resistance and therapeutic opportunities
AL-Ejeh, Fares, Smart, Chanel E., Morrison, Brian J., Chenevix-Trench, Georgia, Lopez, J. Alejandro, Lakhani, Sunil R., Brown, Michael P. and Khanna, Kum Kum (2011). Breast cancer stem cells: Treatment resistance and therapeutic opportunities. Carcinogenesis, 32 (5), 650-658. doi: 10.1093/carcin/bgr028
2011
Journal Article
A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice
Youngson, N. A., Vickaryous, N., van der Horst, A., Epp, T., Harten, S., Fleming, J. S., Khanna, K. K., de Kretser, D. M. and Whitelaw, Emma (2011). A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice. Mammalian Genome, 22 (3-4), 235-248. doi: 10.1007/s00335-011-9317-7
Funding
Current funding
Supervision
Availability
- Honorary Professor Kum Kum Khanna is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Functional validation of therapeutic targets for basal breast cancer
Principal Advisor
-
Doctor Philosophy
Understanding novel regulators of mitosis and their implication in cancer
Principal Advisor
-
Doctor Philosophy
Designing Therapeutic Strategies Targeting KRAS
Associate Advisor
Completed supervision
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2016
Doctor Philosophy
Novel therapeutic targets in breast cancer: From functional validation to therapeutic application
Principal Advisor
-
2013
Doctor Philosophy
Understanding the roles of CEP55 and alphaB-Crystallin in Oncogenesis
Principal Advisor
-
2010
Doctor Philosophy
Tousled like kinases: phosphorylation and function during the cell cycle
Principal Advisor
-
-
2008
Doctor Philosophy
The Functional Characterisation of Centrobin in Endocytic Trafficking and Microtubule Dynamics
Principal Advisor
Other advisors: Honorary Professor Nathan Subramaniam, Professor Robert Parton
-
2006
Doctor Philosophy
FUNTIONAL CHARACTERISATION OF BCOR-L1, A NOVEL COREPRESSOR PROTEIN
Principal Advisor
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2024
Doctor Philosophy
Understanding the role and regulation of the FBXL4-BNIP3/NIX pathway in mitophagy
Associate Advisor
Other advisors: Dr Mathew Jones, Dr Melissa Reichelt, Dr Julia Pagan
-
2020
Doctor Philosophy
Role of nucleic acid binding proteins in oocyte development and female fertility
Associate Advisor
Other advisors: Professor Hayden Homer
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2020
Doctor Philosophy
The Role of Glycan-related Genes Expression in Triple-negative Breast Cancer Pathogenesis
Associate Advisor
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2019
Master Philosophy
Radiosensitization of Prostate Cancer by Nanoparticle Mediated RNA Interference
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Christopher Howard, Professor Kristofer Thurecht
-
2016
Doctor Philosophy
Computational analysis of DNA repair pathways in breast cancer
Associate Advisor
Other advisors: Associate Professor Peter Simpson
-
2012
Doctor Philosophy
Various approaches to identify breast cancer susceptibility genes.
Associate Advisor
Other advisors: Professor Grant Montgomery
-
2008
Doctor Philosophy
BRCA1 interactors and cancer
Associate Advisor
Other advisors: Honorary Professor Amanda Spurdle
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