Honorary Professor

Kum Kum Khanna

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Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis

Search Professor Kum Kum Khanna’s works on UQ eSpace

204 works between 1995 and 2025
All (204) Journal Article (191) Other Outputs (1) Conference Publication (12)

141 - 160 of 204 works

2007

Journal Article

Mutation analysis of five candidate genes in familial breast cancer

Marsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007). Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 (3), 377-389. doi: 10.1007/s10549-006-9461-z

Mutation analysis of five candidate genes in familial breast cancer

2007

Journal Article

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP

Pagan, Julia K., Arnold, Jeremy, Hanchard, Kim J., Kumar, Raman, Bruno, Tiziana, Jones, Mathew J.K., Richard, Derek J., Forrest, Alistair, Spurdle, Amanda, Verdin, Eric, Crossley, Merlin, Fanciulli, Maurizio, Chenevix-Trench, Georgia, Young, David B. and Khanna, Kum Kum (2007). A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. Journal of Biological Chemistry, 282 (20), 15248-15257. doi: 10.1074/jbc.M700246200

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP

2007

Journal Article

Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer

Pylkas, K., Tommiska, J., Syrjakoski, K., Kere, J., Gatei, M., Waddell, N., Allinen, M., Karppinen, SM., Rapakko, K., Kaariainen, H., Aittomaki, K., Blomqvist, C., Mustonen, A., Holli, K., Khanna, K.K., Kallioniemi, O.P., Nevanlinna, H. and Winqvist, R. (2007). Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer. Carcinogenesis, 28 (5), 1040-1045. doi: 10.1093/carcin/bgl237

Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer

2007

Journal Article

From selenium to selenoproteins: Synthesis, identity, and their role in human health

Papp, Laura Vanda, Lu, Jun, Holmgren, Arne and Khanna, Kum Kum (2007). From selenium to selenoproteins: Synthesis, identity, and their role in human health. Antioxidants & Redox Signaling, 9 (7), 775-806. doi: 10.1089/ars.2007.1528

From selenium to selenoproteins: Synthesis, identity, and their role in human health

2007

Journal Article

BCoR-L1 variation and breast cancer

Lose, Felicity, Arnold, Jeremy, Young, David B., Brown, Carolyn J., Mann, Graham J., Pupo, Gulietta M., Khanna, Kum Kum, Chenevix-Trench, Georgia and Spurdle, Amanda B. (2007). BCoR-L1 variation and breast cancer. Breast Cancer Research, 9 (4) R54, 1-12. doi: 10.1186/bcr1759

BCoR-L1 variation and breast cancer

2006

Journal Article

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

Bruno, Tiziana, De Nicola, Francesca, Iezzi, Simona, Lecis, Daniele, D'Angelo, Carmen, Di Padova, Monica, Corbi, Nicoletta, Dimiziani, Leopoldo, Zannini, Laura, Jekimovs, Christian, Scarsella, Marco, Porrello, Alessandro, Chersi, Alberto, Crescenzi, Marco, Leonetti, Carlo, Khanna, Kum Kum, Soddu, Silvia, Floridi, Aristide, Passananti, Claudio, Domenico Delia and Fanciulli, Maurizio (2006). Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint. Cancer Cell, 10 (6), 473-486. doi: 10.1016/j.ccr.2006.10.012

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

2006

Journal Article

Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling

Waddell, Nic, Jonnalagadda, Jyoti, Marsh, Anna, Grist, Scott, Jenkins, Mark, Hobson, Karen, Taylor, Malcolm, Lindeman, Geoff J., Tavtigian, Sean V., Suthers, Graeme, Goldgar, David, Oefner, Peter J., kConFab Investigators, Taylor, Darrin, Grimmond, Sean, Khanna, Kum Kum and Chenevix-Trench, Georgia (2006). Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling. Genes Chromosomes and Cancer, 45 (12), 1169-1181. doi: 10.1002/gcc.20381

Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling

2006

Journal Article

EDD mediates DNA damage-induced activation of CHK2

Henderson, Michelle J., Munoz, Marcia A, Saunders, Darren N., Clancy, Jennifer L., Russell, Amanda J., Williams, Brandi, Pappin, Darryl, Khanna, Kum Kum, Jackson, Stephen P., Sutherland, Robert L. and Watts, Colin K. W. (2006). EDD mediates DNA damage-induced activation of CHK2. Journal of Biological Chemistry, 281 (52), 39990-40000. doi: 10.1074/jbc.M602818200

EDD mediates DNA damage-induced activation of CHK2

2006

Journal Article

Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers

Deans, Andrew J., Khanna, Kum Kum, McNees, Carolyn J., Mercurio, Ciro, Heierhorst, Jörg and McArthur, Grant A. (2006). Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers. Cancer Research, 66 (16), 8219-8226. doi: 10.1158/0008-5472.CAN-05-3945

Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers

2006

Journal Article

BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells

Kang, Hyo Jin, Kim, Hee Jeong, Kim, Sang Keun, Barouki, Robert, Cho, Chi-Heum, Khanna, Kum Kum, Rosen, Eliot M. and Bae, Insoo (2006). BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells. The Journal of Biological Chemistry., 281 (21), 14654-14662. doi: 10.1074/jbc.M601613200

BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells

2006

Journal Article

The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function

Papp, Laura V., Lu, Jun, Striebel, Frank, Kennedy, Derek, Holmgren, Arne and Khanna, Kum Kum (2006). The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Molecular & Cellular Biology, 26 (13), 4895-4910. doi: 10.1128/MCB.02284-05

The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function

2006

Journal Article

Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage

Khanna, Kum Kum, Gatei, Magtouf and Tribbick, Gordon (2006). Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage. Methods in Molecular Medicine, 120, 441-452. doi: 10.1385/1-59259-969-9:441

Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage

2005

Journal Article

Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation

Jung, Cha-Gyun, Kim, Hye-Jung, Kawaguchi, Makoto, Khanna, Kum Kum, Hida, Hideki, Asai, Kiyofumi, Nishino, Hitoo and Miura, Yutaka (2005). Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development, 132 (23), 5137-5145. doi: 10.1242/dev.02098

Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation

2005

Journal Article

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association

Young, David B., Jonnalagadda, Jyoti, Gatei, Magtouf, Jans, David A., Meyn, Stephen and Khanna, Kum Kum (2005). Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association. The Journal of Biological Chemistry, 280 (30), 27587-27594. doi: 10.1074/jbc.M411689200

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association

2005

Journal Article

Two ATM variants and breast cancer risk

Thompson, Deborah, Antoniou, Antonis C., Jenkins, Mark, Marsh, Anna, Chen, Xiaoqing, Wayne, Tierney, Tesoriero, Andrea, Milne, Roger, Spurdle, Amanda, Thorstenson, Yvonne, Southey, Melissa, Giles, Graham G., kConFab Investigators,, Khanna, Kum Kum, Sambrook, Joseph, Oefner, Peter, Goldgar, David, Hopper, John L., Easton, Doug and Chenevix-Trench, Georgia (2005). Two ATM variants and breast cancer risk. Human Mutation, 25 (6), 594-595. doi: 10.1002/humu.9344

Two ATM variants and breast cancer risk

2005

Journal Article

Involvement of human MOF in ATM function

Gupta, Arun, Sharma, Girdhar G., Young, Charles S. H., Agarwal, Manjula, Smith, Edwin R., Paull, Tanya T., Lucchesi, John C., Khanna, Kum Kum, Ludwig, Thomas and Pandita, Tej K. (2005). Involvement of human MOF in ATM function. Molecular and Cellular Biology, 25 (12), 5292-5305. doi: 10.1128/MCB.25.12.5292-5305.2005

Involvement of human MOF in ATM function

2005

Journal Article

Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis

Fabbro, Megan, Zhou, Bin-Bing, Takahasi, Mikiko, Sarcevic, Boris, Lal, Preeti, Graham, Mark E., Gabrielli, Brian G., Robinson, Phillip J., Nigg, Erich A., Ono, Yoshitaka and Khanna, Kum Kum (2005). Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental Cell, 9 (4), 477-488. doi: 10.1016/j.devcel.2005.09.003

Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis

2005

Journal Article

Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals

Jekimovs, C. R., Chen, X., Arnold, J., Gatei, M., Richardson, D. J., kConFab Investigators, Spurdle, A. B., Khanna, K. K. and Chenevix-Trench, G. (2005). Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals. British Journal Of Cancer, 92 (4), 784-790. doi: 10.1038/sj.bjc.6602381

Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals

2004

Journal Article

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A

Goodarzi, Aaron A, Jonnalagadda, Jyoti C., Douglas, Pauline, Young, David, Ye, Ruiqiong, Moorhead, Greg B. G., Lees-Miller, Susan P. and Khanna, Kum Kum (2004). Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. The EMBO Journal, 23 (22), 4451-4461. doi: 10.1038/sj.emboj.7600455

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A

2004

Journal Article

ATM and Genome Maintenance: Defining Its Role in Breast Cancer Susceptibility

Khanna, Kum Kum and Chenevix-Trench, Georgia (2004). ATM and Genome Maintenance: Defining Its Role in Breast Cancer Susceptibility. Journal of Mammary Gland Biology and Neoplasia, 9 (3), 247-262. doi: 10.1023/B:JOMG.0000048772.92326.a1

ATM and Genome Maintenance: Defining Its Role in Breast Cancer Susceptibility

Current funding

  • 2026 - 2028
    Optimisation of endometrial cancer treatment using ex vivo Patient-Derived Organoids/tumouroids.
    Mary Elizabeth Courier Research Scholarship
    Open grant
  • 2024 - 2026
    Targeting the redox niche in triple-negative breast cancer to treat brain metastases
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2024 - 2027
    Targeting metstatic breast cancer by oligonucleotide therapeutics with the FDA lipid nanoparticles (LNP) delivery system.
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant

Past funding

  • 2024
    Exploitation of immunogenicity of Cep 55 to enhance efficacy of therapy for triple-negative breast cancer
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2022 - 2025
    Targeting CEP55 in Triple-Negative Breast Cancer (US DoD CDMRP grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Optimising systemic therapies of metastatic and recurrent triple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Functional validation of therapeutic targets for basal breast cancer

    Principal Advisor

  • Doctor Philosophy

    Validation of biomarkers and therapeutic targets to predict therapy response and sensitise high-grade serous ovarian cancer (HGSC) to chemotherapy.

    Principal Advisor

  • Doctor Philosophy

    A mitotic switch: serine 125 phosphorylation of MLKL links cell division to cell fate

    Principal Advisor

  • Doctor Philosophy

    Discovering therapies of metastatic and recurrenttriple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Investigating the diagnostic and functional significance of specific epigenomic features in triple-negative breast cancer (TNBC)

    Associate Advisor

    Other advisors: Dr Jodi Saunus

  • Doctor Philosophy

    Breaking barriers: unlocking the potential of cytomegalovirus-specific T cells in allogeneic CAR T cell therapies

    Associate Advisor

  • Doctor Philosophy

    Designing Therapeutic Strategies Targeting KRAS

    Associate Advisor

Completed supervision

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