Honorary Professor

Kum Kum Khanna

Email: 

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis

Search Professor Kum Kum Khanna’s works on UQ eSpace

197 works between 1995 and 2025
All (197) Journal Article (185) Conference Publication (11) Other Outputs (1)

121 - 140 of 197 works

2010

Journal Article

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

2010

Journal Article

Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

Lakhani, Sunil R., Khanna, Kum K. and Chenevix-Trench, Georgia (2010). Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?. Breast Cancer Research, 12 (2) 104, 104-1-104-2. doi: 10.1186/bcr2483

Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

2010

Journal Article

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

2009

Journal Article

Cep55 stabilization is required for normal execution of cytokinesis

Armando van der Horst, Jacinta Simmons and Kum Kum Khanna (2009). Cep55 stabilization is required for normal execution of cytokinesis. Cell Cycle, 8 (22), 3742-3749. doi: 10.4161/cc.8.22.10047

Cep55 stabilization is required for normal execution of cytokinesis

2009

Journal Article

Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair

Emma Bolderson, Derek J. Richard, Bin-Bing S. Zhou and Kum Kum Khanna (2009). Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair. Clinical Cancer Research, 15 (20), 6314-6320. doi: 10.1158/1078-0432.CCR-09-0096

Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair

2009

Journal Article

Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X)

Caterina Di Cosmo, Neil McLellan, Xiao-Hui Liao, Kum Kum Khanna, Roy E. Weiss, Laura Papp and Samuel Refetoff (2009). Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X). Journal of Clinical Endocrinology and Metabolism, 94 (10), 4003-4009. doi: 10.1210/jc.2009-0686

Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X)

2009

Journal Article

INTS3 controls the hSSB1-mediated DNA damage response

Jeffrey R. Skaar, Derek J. Richard, Anita Saraf, Alfredo Toschi, Emma Bolderson, Laurence Florens, Michael P. Washburn, Kum Kum Khanna and Michele Pagano (2009). INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology, 187 (1), 25-32. doi: 10.1083/jcb.200907026

INTS3 controls the hSSB1-mediated DNA damage response

2009

Journal Article

The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55

Armando van der Horst and Kum Kum Khanna (2009). The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55. Cancer Research, 69 (16), 6651-6659. doi: 10.1158/0008-5472.CAN-09-0825

The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55

2009

Journal Article

hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response

Yongjiang Li, Emma Bolderson, Rakesh Kumar, Parameswary A. Muniandy, Yutong Xue, Derek J. Richard, Michael Seidman, Tej K. Pandita, Kum Kum Khanna and Weidong Wang (2009). hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response. Journal of Biological Chemistry, 284 (35), 23525-23531.. doi: 10.1074/jbc.C109.039586

hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response

2009

Journal Article

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair

Arun Gupta, Qin Yang, Raj K. Pandita, Clayton R. Hunt, Tao Xiang, Sandeep Misri, Sicong Zeng, Julia Pagan, Jessie Jeffery, Janusz Puc, Rakesh Kumar, Zhihui Feng, Simon N. Powell, Audesh Bhat, Tomoko Yaguchi, Renu Wadhwa, Sunil C. Kaul, Ramon Parsons, Kum Kum Khanna and Tej K. Pandita (2009). Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle, 8 (14), 2198-2210. doi: 10.4161/cc.8.14.8947

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair

2009

Journal Article

Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis

Richard‌, Derek J., Bolderson‌, Emma and Khanna, Kum Kum (2009). Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology, 44 (2-3), 98-116. doi: 10.1080/10409230902849180

Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis

2009

Journal Article

Involvement of Exo1b in DNA damage-induced apoptosis

Emma Bolderson, Derek J. Richard, Winfried Edelmann and Kum Kum Khanna (2009). Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research, 37 (10), 3452-3463. doi: 10.1093/nar/gkp194

Involvement of Exo1b in DNA damage-induced apoptosis

2009

Journal Article

The actin-binding and bundling protein, EPLIN, is required for cytokinesis

Megan Chircop, Vanessa Oakes, Mark E. Graham, Maggie P.C. Ma, Charlotte M. Smith, Phillip J. Robinson and Kum Kum Khanna (2009). The actin-binding and bundling protein, EPLIN, is required for cytokinesis. Cell Cycle, 8 (5), 757-764. doi: 10.4161/cc.8.5.7878

The actin-binding and bundling protein, EPLIN, is required for cytokinesis

2008

Journal Article

Functional characterization of alternatively spliced human SECISBP2 transcript variants

Papp, Laura V., Wang, Junning, Kennedy, Derek, Boucher, Didier, Zhang, Yan, Gladysheve, Vadim N., Sing, Ravindra N. and Khanna, Kum Kum (2008). Functional characterization of alternatively spliced human SECISBP2 transcript variants. Nucleic Acids Research, 36 (22), 7192-7206. doi: 10.1093/nar/gkn829

Functional characterization of alternatively spliced human SECISBP2 transcript variants

2008

Journal Article

Correction: BCoR-L1 variation and breast cancer

Lose, Felicity, Arnold, Jeremy, Young, David B., Brown, Carolyn J., Mann, Graham J., Pupo, Gulietta M., Khanna, Kum K., Chenevix-Trench, Georgia and Spurdle, Amanda B. (2008). Correction: BCoR-L1 variation and breast cancer. Breast Cancer Research, 10 (5) 406. doi: 10.1186/bcr2153

Correction: BCoR-L1 variation and breast cancer

2008

Journal Article

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

Richard, Derek J., Bolderson, Emma, Cubeddu, Liza, Wadsworth, Ross I. M., Savage, Kienan, Sharma, Girdhar G., Nicolette, Matthew L., Tsvetanov, Sergie, McIlwraith, Michael J., Pandita, Raj K., Takeda, Shunichi, Hay, Ronald T., Gautier, Jean, West, Stephen C., Paull, Tanya T., Pandita, Tej K., White, Malcolm F. and Khanna, Kum Kum (2008). Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature, 453 (7195), 677-681. doi: 10.1038/nature06883

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

2007

Journal Article

Mutation analysis of five candidate genes in familial breast cancer

Marsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007). Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 (3), 377-389. doi: 10.1007/s10549-006-9461-z

Mutation analysis of five candidate genes in familial breast cancer

2007

Journal Article

Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer

Pylkas, K, Tommiska, J, Syrjakoski, K, Kere, J, Gatei, M, Waddell, N, Allinen, M, Karppinen, SM, Rapakko, K, Kaariainen, H, Aittomaki, K, Blomqvist, C, Mustonen, A, Holli, K, Khanna, KK, Kallioniemi, OP, Nevanlinna, H and Winqvist, R (2007). Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer. Carcinogenesis, 28 (5), 1040-1045. doi: 10.1093/carcin/bgl237

Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer

2007

Journal Article

From selenium to selenoproteins: Synthesis, identity, and their role in human health

Papp, Laura Vanda, Lu, Jun, Holmgren, Arne and Khanna, Kum Kum (2007). From selenium to selenoproteins: Synthesis, identity, and their role in human health. Antioxidants & Redox Signaling, 9 (7), 775-806. doi: 10.1089/ars.2007.1528

From selenium to selenoproteins: Synthesis, identity, and their role in human health

2007

Journal Article

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP

Pagan, Julia K., Arnold, Jeremy, Hanchard, Kim J., Kumar, Raman, Bruno, Tiziana, Jones, Mathew J.K., Richard, Derek J., Forrest, Alistair, Spurdle, Amanda, Verdin, Eric, Crossley, Merlin, Fanciulli, Maurizio, Chenevix-Trench, Georgia, Young, David B. and Khanna, Kum Kum (2007). A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. Journal of Biological Chemistry, 282 (20), 15248-15257. doi: 10.1074/jbc.M700246200

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP

Current funding

  • 2024 - 2025
    Targeting the redox niche in triple-negative breast cancer to treat brain metastases
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2024 - 2027
    Targeting metstatic breast cancer by oligonucleotide therapeutics with the FDA lipid nanoparticles (LNP) delivery system.
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2022 - 2025
    Targeting CEP55 in Triple-Negative Breast Cancer (US DoD CDMRP grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2024
    Exploitation of immunogenicity of Cep 55 to enhance efficacy of therapy for triple-negative breast cancer
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant

Availability

Honorary Professor Kum Kum Khanna is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Functional validation of therapeutic targets for basal breast cancer

    Principal Advisor

  • Doctor Philosophy

    Understanding novel regulators of mitosis and their implication in cancer

    Principal Advisor

  • Doctor Philosophy

    Optimising systemic therapies of metastatic and recurrent triple-negative breast cancer using next generation 3D models

    Principal Advisor

  • Doctor Philosophy

    Breaking barriers: unlocking the potential of cytomegalovirus-specific T cells in allogeneic CAR T cell therapies

    Associate Advisor

  • Doctor Philosophy

    Designing Therapeutic Strategies Targeting KRAS

    Associate Advisor

  • Doctor Philosophy

    Investigating the diagnostic and functional significance of specific epigenomic features in triple-negative breast cancer (TNBC)

    Associate Advisor

    Other advisors: Dr Jodi Saunus

Completed supervision

Enquiries

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