Professor Peter Cabot
Professor

Peter Cabot

Email: 
Phone: 
+61 7 334 61854

Background

Peter Cabot is the Professor and Head of School in the School of Pharmacy. He joined the School staff in this position in 1999 after completing postdoctoral positions at Johns Hopkins University, Baltimore USA, The NIH, Baltimore USA and within the School of Pharmacy at UQ.

The primary focus of my research is on the elucidation of the peripheral mechanisms involved in analgesia associated with inflammation. Key discoveries were made in this field that highlighted the importance of the immune system in inflammatory pain. The results of which were published in the notable journals; JBC, PAIN, Nature Medicine and The Journal of Clinical Investigation.

Availability

Professor Peter Cabot is:
Available for supervision
Media expert

Fields of research

Clinical sciences Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Applied Science, Charles Sturt University
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Opioids in inflammation

    In the area I work as a translational scientist, exploring drug discovery of novel opioids and inflammatory mechanisms as well as developing new alternatives, paring this with translational work into preclinical and clinical studies looking for better outcomes for patients.

  • Biotransformation of Opioids in Disease

  • Pain in Inflammatory Diseases

  • Natural Products Drug Discovery

Research impacts

Our current research is focussed on novel opioid ligands that target opioid receptors aligned with less addictive properties, bioactivity of endogenous and natural products that may provide insights into better pain therapy or reduction in inflammatory disorders such as sinusitis.

Search Professor Peter Cabot’s works on UQ eSpace

158 works between 1992 and 2024
All (158) Journal Article (92) Book Chapter (1) Conference Publication (61) Other Outputs (4)

121 - 140 of 158 works

2005

Conference Publication

Pain in immune-compromised patients

Stein, C., Glare, P.A., Cabot, P. J. and Milligan, E.D. (2005). Pain in immune-compromised patients. 11th World Congress on Pain, Sydney, 21-26 Aug. 2005. USA: IASP Press.

Pain in immune-compromised patients

2005

Conference Publication

Acidic pH enhances morphine inhibition of high-K2+ induced Ca2+ responses in dorsal root ganglion neurons

Kapitzke, D., Hermanussen, S.F., Jenkins, N., Hua, S., Vetter, I., Monteith, G.R. and Cabot, P.J. (2005). Acidic pH enhances morphine inhibition of high-K2+ induced Ca2+ responses in dorsal root ganglion neurons. 11th World Congress on Pain, Sydney, NSW, Australia, 21-26 August, 2005. Seattle, WA, U.S.A.: IASP Press.

Acidic pH enhances morphine inhibition of high-K2+ induced Ca2+ responses in dorsal root ganglion neurons

2005

Conference Publication

Pioglitazone treatment prevents relapse in a multiple relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

Peiris, M., Roberts-Thomson, S. J., Monteith, G. R. and Cabot, P. J. (2005). Pioglitazone treatment prevents relapse in a multiple relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. Joint Meeting of ASCEPT and APSA, Melbourne, Vic, Australia, 4-7 December, 2005. Melbourne, Vic, Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Pioglitazone treatment prevents relapse in a multiple relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

2005

Conference Publication

Insulin implants prevent the temporal development of tactile allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic Wistar rats

Otto, K. J., Wyse, B. D., Cabot, P. J. and Smith, M. T. (2005). Insulin implants prevent the temporal development of tactile allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic Wistar rats. 11th World Congress on Pain, Sydney, 21-26 Aug. 2005. USA: IASP Press.

Insulin implants prevent the temporal development of tactile allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic Wistar rats

2005

Conference Publication

Spinal manual therapy induces mechanical hypoalgesia in an acute inflammatory animal model

Souvlis, T., Barton, T., Mihell, J. E. and Cabot, P. J. (2005). Spinal manual therapy induces mechanical hypoalgesia in an acute inflammatory animal model. 11th World Congress on Pain, Sydney, 21-26 Aug. 2005. USA: IASP Press.

Spinal manual therapy induces mechanical hypoalgesia in an acute inflammatory animal model

2005

Journal Article

Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws of Wistar rat

Laakso, EL and Cabot, PJ (2005). Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws of Wistar rat. Photomedicine And Laser Surgery, 23 (1), 32-35. doi: 10.1089/pho.2005.23.32

Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws of Wistar rat

2005

Conference Publication

Assessment of fucoidin efficacy in Ab-peptide induced Alzheimer's disease model

Patel, A., Smith, M. T., South, S. M. and Cabot, P. J. (2005). Assessment of fucoidin efficacy in Ab-peptide induced Alzheimer's disease model. Joint Meeting of ASCEPT and APSA, Melbourne, 4-7 December 2005. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Assessment of fucoidin efficacy in Ab-peptide induced Alzheimer's disease model

2005

Conference Publication

Opioid inhibition of TRPV1-mediated calcium currents in cultured dorsal root ganglion neurones and a HEK293 cell line stably expressing TRPV1 and MOR

Vetter, I., Wyse, B. D., Monteith, G. R., Roberts-Thomson, S. J. and Cabot, P. J. (2005). Opioid inhibition of TRPV1-mediated calcium currents in cultured dorsal root ganglion neurones and a HEK293 cell line stably expressing TRPV1 and MOR. 11th World Congress on Pain, Sydney, NSW, Australia, 21-26 August, 2005. Seattle, WA, U.S.A.: International Association for the Study of Pain (IASP) Press.

Opioid inhibition of TRPV1-mediated calcium currents in cultured dorsal root ganglion neurones and a HEK293 cell line stably expressing TRPV1 and MOR

2005

Conference Publication

Blockade of relapse with pioglitazone in a multiple relapsing-remitting experimental autoimmune encephalomyelitis in C57BL/6 mice

Peiris, M., Roberts-Thomson, S. J., Monteith, G. R. and Cabot, P. J. (2005). Blockade of relapse with pioglitazone in a multiple relapsing-remitting experimental autoimmune encephalomyelitis in C57BL/6 mice. 5th Annual Health & Medical Research Conference of Queensland, Brisbane, Qld, Australia, 3-4 November, 2005. Brisbane, Qld, Australia: Queensland Health.

Blockade of relapse with pioglitazone in a multiple relapsing-remitting experimental autoimmune encephalomyelitis in C57BL/6 mice

2004

Journal Article

Reduction of β-Endorphin-Containing Immune Cells in Inflamed Paw Tissue Corresponds with a Reduction in Immune-Derived Antinociception: Reversible by Donor Activated Lymphocytes

Hermanussen, S., Do, M. H. and Cabot, P. J. (2004). Reduction of β-Endorphin-Containing Immune Cells in Inflamed Paw Tissue Corresponds with a Reduction in Immune-Derived Antinociception: Reversible by Donor Activated Lymphocytes. Anesthesia And Analgesia, 98 (3), 723-729. doi: 10.1213/01.ANE.0000099369.23397.D7

Reduction of β-Endorphin-Containing Immune Cells in Inflamed Paw Tissue Corresponds with a Reduction in Immune-Derived Antinociception: Reversible by Donor Activated Lymphocytes

2004

Conference Publication

Experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice: A multiple relapsing model of multiple sclerosis

Peiris, M., Roberts-Thomson, S. J., Monteith, G. R. and Cabot, P. J. (2004). Experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice: A multiple relapsing model of multiple sclerosis. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 Nov - 1 Dec 2004. Brisbane: Qld Government.

Experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice: A multiple relapsing model of multiple sclerosis

2004

Conference Publication

A novel multiple relapsing model of multiple sclerosis: Experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

Roberts-Thomson, S. J., Peiris, M., Monteith, G. R. and Cabot, P. J. (2004). A novel multiple relapsing model of multiple sclerosis: Experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. Melbourne Regional Meeting of ASCEPT, Melbourne University, 30 November, 2004. Melbourne, Vic, Australia: Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT).

A novel multiple relapsing model of multiple sclerosis: Experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

2004

Conference Publication

Effect of insulin treatment on diabetic characteristics in the STZ-diabetic rat

Otto, K. J., Wyse, B. D., Cabot, P. J. and Smith, M. T. (2004). Effect of insulin treatment on diabetic characteristics in the STZ-diabetic rat. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 Nov - 1 Dec 2004. Brisbane: Qld Government.

Effect of insulin treatment on diabetic characteristics in the STZ-diabetic rat

2004

Conference Publication

Beta -endorphin inhibition of capsaicin induced calcium responses in cultured dorsal root ganglion neurones is enhanced at acidic pH's

Vetter, I., Hermanussen, S. F., Monteith, G. R. and Cabot, P. J. (2004). Beta -endorphin inhibition of capsaicin induced calcium responses in cultured dorsal root ganglion neurones is enhanced at acidic pH's. CPT2004: 8th World Conference on Clinical Pharmacology & Therapeutics 2004, Brisbane, Qld, Australia, 1-6 August, 2004. Melbourne, Vic, Australia: Blackwell Publishing.

Beta -endorphin inhibition of capsaicin induced calcium responses in cultured dorsal root ganglion neurones is enhanced at acidic pH's

2004

Conference Publication

Direct interaction between lymphocytes and cultured dorsal root ganglia neurones

Hua, S. and Cabot, P. J. (2004). Direct interaction between lymphocytes and cultured dorsal root ganglia neurones. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 Nov - 1 Dec 2004. Brisbane: Qld Government.

Direct interaction between lymphocytes and cultured dorsal root ganglia neurones

2004

Conference Publication

The effect of acidic pH on morphine inhibition of high-K+ induced CA2+ responses in dorsal root ganglion neurons

Kapitzke, D., Hermanussen, S. F., Monteith, G. R., Brown, L. C. and Cabot, P. J. (2004). The effect of acidic pH on morphine inhibition of high-K+ induced CA2+ responses in dorsal root ganglion neurons. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 Nov - 1 Dec 2004. Brisbane: Qld. Government.

The effect of acidic pH on morphine inhibition of high-K+ induced CA2+ responses in dorsal root ganglion neurons

2004

Conference Publication

Beta-endorphin inhibition of capsaicin induced calcium responses in cultured dorsal root ganglion neurones is enhanced at acidic pH

Vetter, I., Hermanussen, S. F., Monteith, G. R. and Cabot, P. J. (2004). Beta-endorphin inhibition of capsaicin induced calcium responses in cultured dorsal root ganglion neurones is enhanced at acidic pH. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30th November - 1st December, 2004. Brisbane: Queensland Government.

Beta-endorphin inhibition of capsaicin induced calcium responses in cultured dorsal root ganglion neurones is enhanced at acidic pH

2004

Conference Publication

Assessment of working spatial memory utilising T-maze and Morris water-maze for the study of a rodent model of alzheimer's disease

Patel, A., Smith, M. T. and Cabot, P. J. (2004). Assessment of working spatial memory utilising T-maze and Morris water-maze for the study of a rodent model of alzheimer's disease. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 November - 1 December 2004. Brisbane: Qld Government.

Assessment of working spatial memory utilising T-maze and Morris water-maze for the study of a rodent model of alzheimer's disease

2003

Conference Publication

A fresh approach to neuropathic pain management: From the animal model to the patient

Moore, B., Azzopardi, J., Cabot, P. J., Gray, P., Roufogalis, B. and Smith, M. T. (2003). A fresh approach to neuropathic pain management: From the animal model to the patient. Combined meeting of the Australian Pain Society 24th ASM and New Zealand Pain Society 10th ASM, Christchurch, NZ, 9-13 March 2003. Sydney: Australian Pain Society.

A fresh approach to neuropathic pain management: From the animal model to the patient

2003

Conference Publication

Cell adhesion molecules mediate adhesion between immune cells and sensory neurones invitro: A role in inflammatory hyperalgesia

Cabot, P. J., Hermanussen, S. F., Tang, L.W.C. and Monteith, G. R. (2003). Cell adhesion molecules mediate adhesion between immune cells and sensory neurones invitro: A role in inflammatory hyperalgesia. Annual Queensland Health and Medical Scientific Meeting, Brisbane, Qld, Australia, 25-26 November, 2003. Brisbane, Qld, Australia: Queensland Health.

Cell adhesion molecules mediate adhesion between immune cells and sensory neurones invitro: A role in inflammatory hyperalgesia

Past funding

  • 2022 - 2024
    Development of small nerve fibre pathology in chronic whiplash-associated disorder (RBWH Foundation Grant administered by MNHHS)
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2018
    High-throughput ion channel pharmacology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Establishing a High-Throughput, Microwave-Assisted Automated Peptide Synthesis Facility at PACE
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    Murine behavioural phenotyping facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    The assessment of mitochondrial oxygen consumption and cytoplasmic glycolysis in cells to identify and characterize new therapeutic targets for diseases
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    A medium-throughput cell isolation and analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2015
    Perioperative opioids and tumour growth and metastasis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2010
    Analytical instrumentation enabling rapid compound separation and chemical structure analysis via mass fingerprinting
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Cost effective acquisition of an LC-MS/MS system to support CIPDD organics analysis and preclinical and clinical operations
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    High content imaging analysis for bioactive and novel therapeutic target evaluation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Why do people keep hurting their back: A longitudinal study of biological, psychological and social predictors
    NHMRC Project Grant
    Open grant
  • 2009
    A core pharmacy facility for molecular biology, expression and protein post translational modification studies in cancer, cardiovascular, pain and epilepsy research
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Robotics Instrumentation for High Throughput Sample preparation for Increased Productivity of the CIPDD/TetraQ's HPLC-MS/MS Systems for Quantitative Analysis of Organics in a Quality Systems NATA-Acc
    UQ Faculty Co-Funding
    Open grant
  • 2005
    Establishment of an improved model of relapsing MS and the characterisation of the role of Peroxisome Proliferator - activated receoptors alpha and beta
    Multiple Sclerosis Research Australia
    Open grant
  • 2005
    NHMRC_Equipment Grant = DSI Telemetry System
    NHMRC Equipment Grant
    Open grant
  • 2004 - 2005
    NHMRC_Equipment Grant_HLTH_Pharmacy
    NHMRC Equipment Grant
    Open grant
  • 2001
    Immunosupression and inflammatory Pain: the role of the immune system
    Cancer Bequest Fund
    Open grant
  • 2001
    Mechanical and Thermal Nociceptive thresholds in rats with Immunosuppression and Inflammatory Pain.
    UQ Early Career Researcher
    Open grant
  • 2001 - 2003
    Peripheral Mechanisms of Analgesia in Inflammation
    NHMRC Project Grant
    Open grant
  • 2000
    A pilot study investigating the role of Low Level Laser Therapy (LLLT) in an inflammatory model
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2000
    Investigating the role of Low Level Laser Therapy (LLTP) in an inflammatory model
    Centre of Nat. Res. on Disability & Rehab Medicine
    Open grant
  • 1999
    Site-directed trafficking of opioid producing lymphocytes in localised inflammation and the involvement in pain control
    UQ New Staff Research Start-Up Fund
    Open grant

Availability

Professor Peter Cabot is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Peripheral Mechanisms of Analgesia and the Involvement of the Immune System

  • Opioid biotransformation and inflammation

  • Novel opioid peptides for the treatment of addiction and tolerance

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Professor Peter Cabot directly for media enquiries about:

  • Inflammation - pharmacology
  • Pain pharmacology
  • Pharmacology - pain

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