Professor Peter Cabot
Professor

Peter Cabot

Email: 
Phone: 
+61 7 334 61854

Background

Peter Cabot is the Professor and Head of School in the School of Pharmacy. He joined the School staff in this position in 1999 after completing postdoctoral positions at Johns Hopkins University, Baltimore USA, The NIH, Baltimore USA and within the School of Pharmacy at UQ.

The primary focus of my research is on the elucidation of the peripheral mechanisms involved in analgesia associated with inflammation. Key discoveries were made in this field that highlighted the importance of the immune system in inflammatory pain. The results of which were published in the notable journals; JBC, PAIN, Nature Medicine and The Journal of Clinical Investigation.

Availability

Professor Peter Cabot is:
Available for supervision
Media expert

Fields of research

Clinical sciences Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Applied Science, Charles Sturt University
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Opioids in inflammation

    In the area I work as a translational scientist, exploring drug discovery of novel opioids and inflammatory mechanisms as well as developing new alternatives, paring this with translational work into preclinical and clinical studies looking for better outcomes for patients.

  • Biotransformation of Opioids in Disease

  • Pain in Inflammatory Diseases

  • Natural Products Drug Discovery

Research impacts

Our current research is focussed on novel opioid ligands that target opioid receptors aligned with less addictive properties, bioactivity of endogenous and natural products that may provide insights into better pain therapy or reduction in inflammatory disorders such as sinusitis.

Search Professor Peter Cabot’s works on UQ eSpace

158 works between 1992 and 2024
All (158) Journal Article (92) Book Chapter (1) Conference Publication (61) Other Outputs (4)

101 - 120 of 158 works

2007

Journal Article

A model of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice for the characterisation of intervention therapies

Peiris, Madusha, Monteith, Gregory R, Roberts-Thomson, Sarah J. and Cabot, Peter J. (2007). A model of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice for the characterisation of intervention therapies. Journal of Neuroscience Methods, 163 (2), 245-254. doi: 10.1016/j.jneumeth.2007.03.013

A model of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice for the characterisation of intervention therapies

2007

Conference Publication

Modulation of PPARα and PPARβ by ethanol in human breast cancer cell lines

Gopisetty Venkata, Nagaraj, Cabot, Peter, Monteith, Greg and Roberts-Thomson, Sarah (2007). Modulation of PPARα and PPARβ by ethanol in human breast cancer cell lines. 98th Annual Meeting of the American Association for Cancer Research, Los Angeles, U.S., 14-18 April, 2007. Philadelphia, U.S.: American Association for Cancer Research.

Modulation of PPARα and PPARβ by ethanol in human breast cancer cell lines

2007

Conference Publication

Possible mechanism of action for neuroprotective effect of fucoidin in A-beta-induced Alzheimer's disease model

Patel, A., South, S. M., Smith, M. T. and Cabot, P. J. (2007). Possible mechanism of action for neuroprotective effect of fucoidin in A-beta-induced Alzheimer's disease model. Neuroscience 2007, San Diego, U.S., 3-7 November, 2007. Society for Neuroscience.

Possible mechanism of action for neuroprotective effect of fucoidin in A-beta-induced Alzheimer's disease model

2007

Conference Publication

Influence of diet on the temporal development of tactile allodynia and opioid hyposensitivity for 22-wks in the Zucker Diabetic Fatty (ZDF) rat

Cabot, P. J., Otto, K. J., Smith, M. T., South, S. M. and Wyse, B. D. (2007). Influence of diet on the temporal development of tactile allodynia and opioid hyposensitivity for 22-wks in the Zucker Diabetic Fatty (ZDF) rat. Second International Congress on Neuropathic Pain, Berlin, Germany, 7- 10 June 2007. Berlin, Germany: doi: 10.1016/j.ejpain.2007.03.177

Influence of diet on the temporal development of tactile allodynia and opioid hyposensitivity for 22-wks in the Zucker Diabetic Fatty (ZDF) rat

2007

Book Chapter

Stress, cytokines, and peripheral analgesia

Cabot, P. J. (2007). Stress, cytokines, and peripheral analgesia. Cytokines: Stress and Immunity. (pp. 87-100) edited by N. P. Plotnikoff, R. E. Faith, A. J. Murgo and R. A. Good. New York: CRC Press.

Stress, cytokines, and peripheral analgesia

2006

Journal Article

The neural cell adhesion molecule antibody blocks cold water swim stress-induced analgesia and cell adhesion between lymphocytes and cultured dorsal root ganglion neurons

Hua, S., Hermanussen, S., Tang, L., Monteith, G. R. and Cabot, P. J. (2006). The neural cell adhesion molecule antibody blocks cold water swim stress-induced analgesia and cell adhesion between lymphocytes and cultured dorsal root ganglion neurons. Anesthesia and Analgesia, 103 (6), 1558-1564. doi: 10.1213/01.ane.0000243410.61451.c1

The neural cell adhesion molecule antibody blocks cold water swim stress-induced analgesia and cell adhesion between lymphocytes and cultured dorsal root ganglion neurons

2006

Journal Article

The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway

Vetter, Irina, Wyse, Bruce D., Monteith, Gregory R., Roberts-Thomson, Sarah J. and Cabot, Peter J. (2006). The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway. Molecular Pain, 2 (22) 22, 1-16. doi: 10.1186/1744-8069-2-22

The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway

2006

Journal Article

The Effects of pH on Beta-Endorphin and Morphine Inhibition of Calcium Transients in Dorsal Root Ganglion Neurons

Vetter, I., Kapitzke, D., Hermanussen, S., Monteith, G. R. and Cabot, P. J. (2006). The Effects of pH on Beta-Endorphin and Morphine Inhibition of Calcium Transients in Dorsal Root Ganglion Neurons. The Journal of Pain, 7 (7), 488-499. doi: 10.1016/j.jpain.2006.01.456

The Effects of pH on Beta-Endorphin and Morphine Inhibition of Calcium Transients in Dorsal Root Ganglion Neurons

2006

Conference Publication

Identification and quantitation of intact beta-endorphin by LC-MS-MS

Cabot, P. J., Hewavitharana, A., Pham, U. and Shaw, P. N. (2006). Identification and quantitation of intact beta-endorphin by LC-MS-MS. BPC Science: British Pharmaceutical Conference, Manchester UK / Manchester International Convention Centre, 4-6 September 2006. West Sussex, U.K.: John Wiley & Sons. doi: 10.1211/002235706778251393

Identification and quantitation of intact beta-endorphin by LC-MS-MS

2006

Conference Publication

The effects of ethanol on PPARS in MCF-7 human breast cancer cells

Gopisetty Venkata, N., Cabot, P. J., Monteith, G. R. and Roberts-Thomson, S. J. (2006). The effects of ethanol on PPARS in MCF-7 human breast cancer cells. ComBio 2006, Brisbane Convention Centre, Brisbane, Australia, 24-28 September, 2006. Kent Town, South Australia: Australian Society for Biochemistry and Molecular Biology.

The effects of ethanol on PPARS in MCF-7 human breast cancer cells

2006

Conference Publication

Effects of the Mu opioid receptor agonist morphine on TRPV1-mediated capsaicin responses potentiated through PKC and cAMP-dependent PKA pathways

Vetter, I., Wyse, B. D., Monteith, G. R., Roberts-Thomson, S. J. and Cabot, P. J. (2006). Effects of the Mu opioid receptor agonist morphine on TRPV1-mediated capsaicin responses potentiated through PKC and cAMP-dependent PKA pathways. 2006 Neuroscience, Georgia World Congress Center / Altana, Georgia, U.S.A., 11-18 October, 2006. Washington DC, U.S.A.: Society for Neuroscience.

Effects of the Mu opioid receptor agonist morphine on TRPV1-mediated capsaicin responses potentiated through PKC and cAMP-dependent PKA pathways

2006

Journal Article

Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors alpha and gamma in breast

Gopisetty Venkata, Nagaraj, Robinson, Jodie A., Cabot, Peter J., Davis, Barbara, Monteith, Greg R. and Roberts-Thomson, Sarah J. (2006). Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors alpha and gamma in breast. Toxicology Letters, 163 (3), 224-234. doi: 10.1016/j.toxlet.2005.11.001

Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors alpha and gamma in breast

2006

Conference Publication

Assessment of fucoidin efficacy in a beta-peptide induced in Alzheimer's disease model

Patel, A., Smith, M. T., South, S. M. and Cabot, P. J. (2006). Assessment of fucoidin efficacy in a beta-peptide induced in Alzheimer's disease model. Neuroscience 2006, Atlanta, Geogia / Georgia World Congress Center, 14-18 October 2006. USA: Society for Neuroscience.

Assessment of fucoidin efficacy in a beta-peptide induced in Alzheimer's disease model

2006

Conference Publication

The effects of mono (2-ethylhexyl) phthalate, mono-n-butyl phthalate and ethanol on PPARs in MCF-7 human breast cancer cells

Gopisetty Venkata, N., Robinson, J. A., Cabot, P. J., Monteith, G. R. and Roberts-Thomson, S. J. (2006). The effects of mono (2-ethylhexyl) phthalate, mono-n-butyl phthalate and ethanol on PPARs in MCF-7 human breast cancer cells. AACR 97th Annual Meeting 2006: Driving the science: From bench to bedside...and back, Washington, DC, U.S.A., 1-5 April, 2006. Philadelphia, PA, U.S.A.: American Association for Cancer.

The effects of mono (2-ethylhexyl) phthalate, mono-n-butyl phthalate and ethanol on PPARs in MCF-7 human breast cancer cells

2006

Conference Publication

Modulation of TRPV1-mediated capsaicin responses potentiated through PKC and camp-dependent PKA pathways by the Mu opioid receptor agonist morphine

Vetter, I., Wyse, B. D., Monteith, G. R., Roberts-Thomson, S. J. and Cabot, P. J. (2006). Modulation of TRPV1-mediated capsaicin responses potentiated through PKC and camp-dependent PKA pathways by the Mu opioid receptor agonist morphine. ComBio 2006, Brisbane Convention Centre, Brisbane, Australia, 24-28 September, 2006. Kent Town, South Australia: Australian Society for Biochemistry and Molecular Biology.

Modulation of TRPV1-mediated capsaicin responses potentiated through PKC and camp-dependent PKA pathways by the Mu opioid receptor agonist morphine

2006

Conference Publication

Peroxisome-proliferator activated receptor (PPAR) beta/delta and its role inr elapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE)

Peiris, M., Monteith, G. R., Roberts-Thomson, S. J. and Cabot, P. J. (2006). Peroxisome-proliferator activated receptor (PPAR) beta/delta and its role inr elapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE). Neuroscience 2006, Georgia World Congress Center / Altana, Georgia, U.S.A., 11-18 October, 2006. Washington, D.C. U.S.A.: Society for Neuroscience.

Peroxisome-proliferator activated receptor (PPAR) beta/delta and its role inr elapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE)

2006

Conference Publication

Peroxisome-proliferator activated receptors modulate inflammation in relapsing-remitting experimental autoimmune encephalomyelitis

Peiris, M., Monteith, G. R., Roberts-Thomson, S. J. and Cabot, P. J. (2006). Peroxisome-proliferator activated receptors modulate inflammation in relapsing-remitting experimental autoimmune encephalomyelitis. ComBio 2006, Brisbane Convention Centre, Brisbane, Australia, 24-28 September, 2006. Kent Town, South Australia: Australian Society for Biochemistry and Molecular Biology.

Peroxisome-proliferator activated receptors modulate inflammation in relapsing-remitting experimental autoimmune encephalomyelitis

2006

Conference Publication

Insulin implants prevent the temporal development of tactile allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic wistar rats

Otto, K. J., Wyse, B. D., Cabot, P. J. and Smith, M. T. (2006). Insulin implants prevent the temporal development of tactile allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic wistar rats. 26th Annual Scientific Meeting of the Australian Pain Society, Melbourne / Grand Hyatt Hotel, 9-12 April 2006. Melbourne: Australian Pain Society.

Insulin implants prevent the temporal development of tactile allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic wistar rats

2006

Conference Publication

Retrospective drug utilisation evaluation of gabapentin for the treatment of neuropathic pain by the Multidiscplinary Pain Centre, Royal Brisbane and Women's Hospital

Ko, E., Cramond, T R O, Smith, M T and Cabot, P J (2006). Retrospective drug utilisation evaluation of gabapentin for the treatment of neuropathic pain by the Multidiscplinary Pain Centre, Royal Brisbane and Women's Hospital. 2006 Conference of the Queensland Branch of the Society for Hospital Pharmacists of Australia, Carlton Crest / Brisbane, October 2006.

Retrospective drug utilisation evaluation of gabapentin for the treatment of neuropathic pain by the Multidiscplinary Pain Centre, Royal Brisbane and Women's Hospital

2005

Conference Publication

Pioglitazone treatment prevents relapse in a multiple relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

Peiris, M., Roberts-Thomson, S. J., Monteith, G. R. and Cabot, P. J. (2005). Pioglitazone treatment prevents relapse in a multiple relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. Joint Meeting of ASCEPT and APSA, Melbourne, Vic, Australia, 4-7 December, 2005. Melbourne, Vic, Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Pioglitazone treatment prevents relapse in a multiple relapsing-remitting experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice

Past funding

  • 2022 - 2024
    Development of small nerve fibre pathology in chronic whiplash-associated disorder (RBWH Foundation Grant administered by MNHHS)
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2018
    High-throughput ion channel pharmacology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Establishing a High-Throughput, Microwave-Assisted Automated Peptide Synthesis Facility at PACE
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    Murine behavioural phenotyping facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    The assessment of mitochondrial oxygen consumption and cytoplasmic glycolysis in cells to identify and characterize new therapeutic targets for diseases
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    A medium-throughput cell isolation and analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2015
    Perioperative opioids and tumour growth and metastasis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2010
    Analytical instrumentation enabling rapid compound separation and chemical structure analysis via mass fingerprinting
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Cost effective acquisition of an LC-MS/MS system to support CIPDD organics analysis and preclinical and clinical operations
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    High content imaging analysis for bioactive and novel therapeutic target evaluation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Why do people keep hurting their back: A longitudinal study of biological, psychological and social predictors
    NHMRC Project Grant
    Open grant
  • 2009
    A core pharmacy facility for molecular biology, expression and protein post translational modification studies in cancer, cardiovascular, pain and epilepsy research
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Robotics Instrumentation for High Throughput Sample preparation for Increased Productivity of the CIPDD/TetraQ's HPLC-MS/MS Systems for Quantitative Analysis of Organics in a Quality Systems NATA-Acc
    UQ Faculty Co-Funding
    Open grant
  • 2005
    Establishment of an improved model of relapsing MS and the characterisation of the role of Peroxisome Proliferator - activated receoptors alpha and beta
    Multiple Sclerosis Research Australia
    Open grant
  • 2005
    NHMRC_Equipment Grant = DSI Telemetry System
    NHMRC Equipment Grant
    Open grant
  • 2004 - 2005
    NHMRC_Equipment Grant_HLTH_Pharmacy
    NHMRC Equipment Grant
    Open grant
  • 2001
    Immunosupression and inflammatory Pain: the role of the immune system
    Cancer Bequest Fund
    Open grant
  • 2001
    Mechanical and Thermal Nociceptive thresholds in rats with Immunosuppression and Inflammatory Pain.
    UQ Early Career Researcher
    Open grant
  • 2001 - 2003
    Peripheral Mechanisms of Analgesia in Inflammation
    NHMRC Project Grant
    Open grant
  • 2000
    A pilot study investigating the role of Low Level Laser Therapy (LLLT) in an inflammatory model
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2000
    Investigating the role of Low Level Laser Therapy (LLTP) in an inflammatory model
    Centre of Nat. Res. on Disability & Rehab Medicine
    Open grant
  • 1999
    Site-directed trafficking of opioid producing lymphocytes in localised inflammation and the involvement in pain control
    UQ New Staff Research Start-Up Fund
    Open grant

Availability

Professor Peter Cabot is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Peripheral Mechanisms of Analgesia and the Involvement of the Immune System

  • Opioid biotransformation and inflammation

  • Novel opioid peptides for the treatment of addiction and tolerance

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Professor Peter Cabot directly for media enquiries about:

  • Inflammation - pharmacology
  • Pain pharmacology
  • Pharmacology - pain

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