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2018 Journal Article The role of CSF1R-dependent macrophages in control of the intestinal stem-cell nicheSehgal, Anuj, Donaldson, David S., Pridans, Clare, Sauter, Kristin A., Hume, David A. and Mabbott, Neil A. (2018). The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche. Nature Communications, 9 (1) 1272, 1272. doi: 10.1038/s41467-018-03638-6 |
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2025 Journal Article Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutationCarter-Cusack, Dylan, Huang, Stephen, Keshvari, Sahar, Patkar, Omkar, Sehgal, Anuj, Allavena, Rachel, Byrne, Robert A. J., Morgan, B. Paul, Bush, Stephen J., Summers, Kim M., Irvine, Katharine M. and Hume, David A. (2025). Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. PLoS Genetics, 21 (1) e1011525, 1-40. doi: 10.1371/journal.pgen.1011525 |
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2024 Journal Article Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transferBatoon, Lena, Keshvari, Sahar, Irvine, Katharine M., Ho, Eileen, Caruso, Melanie, Patkar, Omkar L., Sehgal, Anuj, Millard, Susan M., Hume, David A. and Pettit, Allison R. (2024). Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer. Journal of Leukocyte Biology, 116 (4), 753-765. doi: 10.1093/jleuko/qiae077 |
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2023 Journal Article Undiagnosed coeliac disease identified by active case finding in first degree relatives of people with coeliac disease in Australia: a prospective observational studyMuir, Richard, Sehgal, Anuj, Tye‐Din, Jason A and Daveson, A James M (2023). Undiagnosed coeliac disease identified by active case finding in first degree relatives of people with coeliac disease in Australia: a prospective observational study. Medical Journal of Australia, 219 (8), 371-373. doi: 10.5694/mja2.52105 |
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2023 Journal Article Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesisSehgal, Anuj, Carter‐Cusack, Dylan, Keshvari, Sahar, Patkar, Omkar, Huang, Stephen, Summers, Kim M., Hume, David A. and Irvine, Katharine M. (2023). Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis. European Journal of Immunology, 53 (8) 2250312, e2250312. doi: 10.1002/eji.202250312 |
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2022 Journal Article CSF1R as a therapeutic target in bone diseases: obvious but not so simpleHume, David A., Batoon, Lena, Sehgal, Anuj, Keshvari, Sahar and Irvine, Katharine M. (2022). CSF1R as a therapeutic target in bone diseases: obvious but not so simple. Current Osteoporosis Reports, 20 (6), 516-531. doi: 10.1007/s11914-022-00757-4 |
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2022 Journal Article A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signallingStables, Jennifer, Green, Emma K., Sehgal, Anuj, Patkar, Omkar L., Keshvari, Sahar, Taylor, Isis, Ashcroft, Maisie E., Grabert, Kathleen, Wollscheid-Lengeling, Evi, Szymkowiak, Stefan, McColl, Barry W., Adamson, Antony, Humphreys, Neil E., Mueller, Werner, Starobova, Hana, Vetter, Irina, Shabestari, Sepideh Kiani, Blurton-Jones, Matthew M., Summers, Kim M., Irvine, Katharine M., Pridans, Clare and Hume, David A. (2022). A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling. Development, 149 (8) dev200237. doi: 10.1242/dev.200237 |
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2021 Journal Article Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissuesMillard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058 |
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2021 Journal Article Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repairSehgal, Anuj, Irvine, Katharine M. and Hume, David A. (2021). Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair. Seminars in Immunology, 54 101509, 101509. doi: 10.1016/j.smim.2021.101509 |
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2021 Journal Article CSF1R-dependent macrophages control postnatal somatic growth and organ maturationKeshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M. and Hume, David A. (2021). CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genetics, 17 (6) e1009605, e1009605. doi: 10.1371/journal.pgen.1009605 |
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2021 Journal Article The mononuclear phagocyte system of the ratHume, David A., Caruso, Melanie, Keshvari, Sahar, Patkar, Omkar L., Sehgal, Anuj, Bush, Stephen J., Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2021). The mononuclear phagocyte system of the rat. The Journal of Immunology, 206 (10), 2251-2263. doi: 10.4049/jimmunol.2100136 |
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2021 Journal Article Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in miceKaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w |
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2020 Journal Article A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte systemGrabert, Kathleen, Sehgal, Anuj, Irvine, Katharine M., Wollscheid-Lengeling, Evi, Ozdemir, Derya D., Stables, Jennifer, Luke, Garry A., Ryan, Martin D., Adamson, Antony, Humphreys, Neil E., Sandrock, Cheyenne J., Rojo, Rocio, Verkasalo, Veera A., Mueller, Werner, Hohenstein, Peter, Pettit, Allison R., Pridans, Clare and Hume, David A. (2020). A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system. Journal of Immunology, 205 (11), 3154-3166. doi: 10.4049/jimmunol.2000835 |
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2019 Journal Article Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter geneIrvine, Katharine M., Caruso, Melanie, Cestari, Michelle Ferrari, Davis, Gemma M., Keshvari, Sahar, Sehgal, Anuj, Pridans, Clare and Hume, David A. (2019). Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene. Journal of Leukocyte Biology, 107 (2) JLB.MA0519-149R, 221-235. doi: 10.1002/jlb.ma0519-149r |
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2018 Journal Article Development of in vitro enteroids derived from bovine small intestinal cryptsHamilton, Carly A., Young, Rachel, Jayaraman, Siddharth, Sehgal, Anuj, Paxton, Edith, Thomson, Sarah, Katzer, Frank, Hope, Jayne, Innes, Elisabeth, Morrison, Liam J. and Mabbott, Neil A. (2018). Development of in vitro enteroids derived from bovine small intestinal crypts. Veterinary Research, 49 (1) 54. doi: 10.1186/s13567-018-0547-5 |
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2017 Journal Article c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epitheliumSehgal, Anuj, Kobayashi, Atsushi, Donaldson, David S. and Mabbott, Neil A. (2017). c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium. Immunobiology, 222 (2), 316-326. doi: 10.1016/j.imbio.2016.09.008 |
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2016 Journal Article Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease SusceptibilityDonaldson, David S., Sehgal, Anuj, Rios, Daniel, Williams, Ifor R. and Mabbott, Neil A. (2016). Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility. PLoS Pathogens, 12 (12) e1006075, e1006075. doi: 10.1371/journal.ppat.1006075 |
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2015 Journal Article Aging and the mucosal immune system in the intestineMabbott, Neil A., Kobayashi, Atsushi, Sehgal, Anuj, Bradford, Barry M., Pattison, Mari and Donaldson, David S. (2015). Aging and the mucosal immune system in the intestine. Biogerontology, 16 (2), 133-145. doi: 10.1007/s10522-014-9498-z |
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2014 Journal Article Characterisation of a novel fc conjugate of macrophage colony-stimulating factorGow, Deborah J, Sauter, Kristin A., Pridans, Clare, Moffat, Lindsey, Sehgal, Anuj, Stutchfield, Ben M., Raza, Sobia, Beard, Philippa M., Tsai, Yi Ting, Bainbridge, Graeme, Boner, Pamela L., Fici, Greg, Garcia-Tapia, David, Martin, Roger A., Oliphant, Theodore, Shelly, John A., Tiwari, Raksha, Wilson, Thomas L., Smith, Lee B., Mabbott, Neil A. and Hume, David A. (2014). Characterisation of a novel fc conjugate of macrophage colony-stimulating factor. Molecular Therapy, 22 (9), 1580-1592. doi: 10.1038/mt.2014.112 |
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2014 Journal Article The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administrationSauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Bain, Calum C., Scott, Charlotte, Moffat, Lindsey, Rojo, Rocío, Stutchfield, Ben M., Davies, Claire L., Donaldson, David S., Renault, Kathleen, McColl, Barry W., Mowat, Alan M., Serrels, Alan, Frame, Margaret C., Mabbott, Neil A. and Hume, David A. (2014). The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE, 9 (8) e105429, 1-12. doi: 10.1371/journal.pone.0105429 |
