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2023

Journal Article

Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation

Yunis, Joseph, Short, Kirsty R. and Yu, Di (2023). Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation. Trends in Microbiology, 31 (6), 644-656. doi: 10.1016/j.tim.2022.12.008

Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation

2023

Journal Article

Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease

Chen, Titi, Cao, Qi, Wang, Ruifeng, Zheng, Guoping, Azmi, Farhana, Lee, Vincent W., Wang, Yuan Ming, Li, Hongqi, Yu, Di, Rogers, Natasha M., Alexander, Stephen I., Harris, David C.H. and Wang, Yiping (2023). Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease. Clinical Immunology, 250 109295, 1-14. doi: 10.1016/j.clim.2023.109295

Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease

2023

Journal Article

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

Chen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

2023

Journal Article

T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance

Gao, Xin, Luo, Kaiming, Wang, Diya, Wei, Yunbo, Yao, Yin, Deng, Jun, Yang, Yang, Zeng, Qunxiong, Dong, Xiaoru, Xiong, Le, Gong, Dongcheng, Lin, Lin, Pohl, Kai, Liu, Shaoling, Liu, Yu, Liu, Lu, Nguyen, Thi HO, Allen, Lilith F., Kedzierska, Katherine, Jin, Yanliang, Du, Mei-Rong, Chen, Wanping, Lu, Liangjing, Shen, Nan, Liu, Zheng, Cockburn, Ian A., Luo, Wenjing and Yu, Di (2023). T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance. eLife, 12 e82217, 1-29. doi: 10.7554/elife.82217

T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance

2023

Journal Article

Dimensionality reduction under scrutiny

Yang, Yang, Tuong, Zewen K. and Yu, Di (2023). Dimensionality reduction under scrutiny. Nature Computational Science, 3 (1), 8-9. doi: 10.1038/s43588-022-00383-1

Dimensionality reduction under scrutiny

2022

Journal Article

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

Gong, Huanle, Ma, Shoubao, Chen, Jia, Yang, Bingyu, Liu, Shuangzhu, Liu, Xin, Han, Jingjing, Wu, Xiaojin, Lei, Lei, Yin, Zhinan, Sun, Hongjian, Yu, Di, Liu, Haiyan, Xu, Yang and Wu, Depei (2022). Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease. Signal Transduction and Targeted Therapy, 7 (1) 319, 1-12. doi: 10.1038/s41392-022-01147-z

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

2022

Journal Article

LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus

Liu, Limin, Hu, Longyuan, Long, Haojun, Zheng, Meiling, Hu, Zhi, He, Ye, Gao, Xiaofei, Du, Pei, Zhao, Hongjun, Yu, Di, Lu, Qianjin and Zhao, Ming (2022). LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus. Clinical and Translational Medicine, 12 (12) e1117, 1-21. doi: 10.1002/ctm2.1117

LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus

2022

Journal Article

Efficacy and Safety of Low-Dose Interleukin 2 for Primary Sjögren Syndrome: A Randomized Clinical Trial

He, Jing, Chen, Jiali, Miao, Miao, Zhang, Ruijun, Cheng, Gong, Wang, Yifan, Feng, Ruiling, Huang, Bo, Luan, Huijie, Jia, Yuan, Jin, Yuebo, Zhang, Xiaoying, Shao, Miao, Wang, Yu, Zhang, Xia, Li, Jing, Zhao, Xiaozhen, Wang, Han, Liu, Tian, Xiao, Xian, Zhang, Xuewu, Su, Yin, Mu, Rong, Ye, Hua, Li, Ru, Liu, Xu, Liu, Yanying, Li, Chun, Liu, Huixin ... Li, Zhanguo (2022). Efficacy and Safety of Low-Dose Interleukin 2 for Primary Sjögren Syndrome: A Randomized Clinical Trial. JAMA Network Open, 5 (11) e2241451, 1-16. doi: 10.1001/jamanetworkopen.2022.41451

Efficacy and Safety of Low-Dose Interleukin 2 for Primary Sjögren Syndrome: A Randomized Clinical Trial

2022

Journal Article

Inhibition of UBA6 by inosine augments tumour immunogenicity and responses

Zhang, Lei, Jiang, Li, Yu, Liang, Li, Qin, Tian, Xiangjun, He, Jingquan, Zeng, Ling, Yang, Yuqin, Wang, Chaoran, Wei, Yuhan, Jiang, Xiaoyue, Li, Jing, Ge, Xiaolu, Gu, Qisheng, Li, Jikun, Wu, Di, Sadler, Anthony J., Yu, Di, Xu, Dakang, Gao, Yue, Yuan, Xiangliang and He, Baokun (2022). Inhibition of UBA6 by inosine augments tumour immunogenicity and responses. Nature Communications, 13 (1) 5413, 1-16. doi: 10.1038/s41467-022-33116-z

Inhibition of UBA6 by inosine augments tumour immunogenicity and responses

2022

Journal Article

Allergen Immunotherapy Reverses Immune Response to SARS-CoV-2 Vaccine in Patients with Allergic Rhinitis: A Prospective Observational Trial

Yao, Yin, Huang, Ao, Deng, Yi-Ke, Liu, Yan, Zhu, Hong-Yu, Wang, Nan, Wang, Zhe-Zheng, Zhu, Rong-Fei, Yu, Di and Liu, Zheng (2022). Allergen Immunotherapy Reverses Immune Response to SARS-CoV-2 Vaccine in Patients with Allergic Rhinitis: A Prospective Observational Trial. American Journal of Respiratory and Critical Care Medicine, 206 (6), 780-783. doi: 10.1164/rccm.202203-0608le

Allergen Immunotherapy Reverses Immune Response to SARS-CoV-2 Vaccine in Patients with Allergic Rhinitis: A Prospective Observational Trial

2022

Journal Article

Targeting TFH cells in human diseases and vaccination: rationale and practice

Yu, Di, Walker, Lucy S. K., Liu, Zheng, Linterman, Michelle A. and Li, Zhanguo (2022). Targeting TFH cells in human diseases and vaccination: rationale and practice. Nature Immunology, 23 (8), 1157-1168. doi: 10.1038/s41590-022-01253-8

Targeting TFH cells in human diseases and vaccination: rationale and practice

2022

Journal Article

Integrative analysis of small RNA and mRNA expression profiles identifies signatures associated with chronic epididymitis

Gong, Jialei, Wang, Peng, Liu, Jin-Chuan, Li, Jianlin, Zeng, Qun-Xiong, Yang, Chen, Li, Yanfeng, Yu, Di, Cao, Dandan and Duan, Yong-Gang (2022). Integrative analysis of small RNA and mRNA expression profiles identifies signatures associated with chronic epididymitis. Frontiers in Immunology, 13 883803, 1-12. doi: 10.3389/fimmu.2022.883803

Integrative analysis of small RNA and mRNA expression profiles identifies signatures associated with chronic epididymitis

2022

Journal Article

Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus

Gao, Xiaofei, Song, Yang, Wu, Jiali, Lu, Shuang, Min, Xiaoli, Liu, Limin, Hu, Longyuan, Zheng, Meiling, Du, Pei, Yu, Yaqin, Long, Hai, Wu, Haijing, Jia, Sujie, Yu, Di, Lu, Qianjin and Zhao, Ming (2022). Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus. Journal of Clinical Investigation, 132 (9) e152345. doi: 10.1172/JCI152345

Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus

2022

Journal Article

Context-dependent regulation of follicular helper T cell survival

Chen, Zhian, Wang, Naiqi, Yao, Yin and Yu, Di (2022). Context-dependent regulation of follicular helper T cell survival. Trends in Immunology, 43 (4), 309-321. doi: 10.1016/j.it.2022.02.002

Context-dependent regulation of follicular helper T cell survival

2022

Journal Article

Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps

Wang, Zhi-Chao, Yao, Yin, Chen, Cai-Ling, Guo, Cui-Lian, Ding, Hong-Xia, Song, Jia, Wang, Zhe-Zheng, Wang, Nan, Li, Xue-Li, Liao, Bo, Yang, Yang, Yu, Di and Liu, Zheng (2022). Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps. Journal of Allergy and Clinical Immunology, 149 (2), 610-623. doi: 10.1016/j.jaci.2021.06.023

Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps

2022

Journal Article

TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis

Yao, Yin, Wang, Zhe-Zheng, Huang, Ao, Liu, Yan, Wang, Nan, Wang, Zhi-Chao, Yang, Lin, Li, Hui-Jun, Xie, Jun-Gang, Zhu, Rong-Fei, Cheng, Li-Ming, Yu, Di and Liu, Zheng (2022). TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis. Clinical and Translational Medicine, 12 (1) e717, e717. doi: 10.1002/ctm2.717

TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis

2022

Journal Article

Evolution of γ chain cytokines: mechanisms, methods and applications

Antczak, Magdalena, Cañete, Pablo F., Chen, Zhian, Belle, Clémence and Yu, Di (2022). Evolution of γ chain cytokines: mechanisms, methods and applications. Computational and Structural Biotechnology Journal, 20, 4746-4755. doi: 10.1016/j.csbj.2022.08.050

Evolution of γ chain cytokines: mechanisms, methods and applications

2022

Journal Article

Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy

Chen, Zhian, Gao, Xin and Yu, Di (2022). Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy. View, 3 (1) 20200103, 20200103. doi: 10.1002/viw.20200103

Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy

2021

Journal Article

Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis

Kang, Hao, Wei, Yunbo, Liu, Ming, Yu, Di and Tao, Yong (2021). Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis. BMC Ophthalmology, 21 (1) 193. doi: 10.1186/s12886-021-01951-1

Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis

2021

Journal Article

Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment

Wang, Shuang, Li, Feng, Ye, Tong, Wang, Jianghua, Lyu, Chengliang, Qing, Shuang, Ding, Zhaowen, Gao, Xiaoyong, Jia, Rongrong, Yu, Di, Ren, Jun, Wei, Wei and Ma, Guanghui (2021). Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment. Science Translational Medicine, 13 (615) eabb6981, eabb6981. doi: 10.1126/scitranslmed.abb6981

Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment