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2025

Journal Article

Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absence

Pazhouhandeh, Mehrdad, Sun, Hongjian and Yu, Di (2025). Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absence. Cell Research, 1-2. doi: 10.1038/s41422-024-01052-w

Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absence

2024

Journal Article

Dysregulation in keratinocytes drives systemic lupus erythematosus onset

Tian, Jingru, Shi, Liqing, Zhang, Dingyao, Yao, Xu, Zhao, Ming, Kumari, Snehlata, Lu, Jun, Yu, Di and Lu, Qianjin (2024). Dysregulation in keratinocytes drives systemic lupus erythematosus onset. Cellular and Molecular Immunology, 22 (1) 6149, 1-14. doi: 10.1038/s41423-024-01240-z

Dysregulation in keratinocytes drives systemic lupus erythematosus onset

2024

Journal Article

IL-1β mediated fibroblast-neutrophil crosstalk promotes inflammatory environment in skin lesions of SLE

Chen, Xiaoyun, OuYang, Lianlian, Qian, Bao, Qiu, Yueqi, Liu, Limin, Chen, Fangqi, Jiang, Wenjuan, Zheng, Meiling, Hu, Zhi, Min, Xiaoli, Wen, Lifang, Wang, Qiaolin, Yu, Di, Jia, Sujie, Lu, Qianjin and Zhao, Ming (2024). IL-1β mediated fibroblast-neutrophil crosstalk promotes inflammatory environment in skin lesions of SLE. Clinical Immunology, 269 110396, 110396. doi: 10.1016/j.clim.2024.110396

IL-1β mediated fibroblast-neutrophil crosstalk promotes inflammatory environment in skin lesions of SLE

2024

Journal Article

Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps

Guo, Cui-Lian, Wang, Chong-Shu, Wang, Zhi-Chao, Liu, Fei-Fan, Liu, Lin, Yang, Yang, Li, Xia, Guo, Bei, Lu, Ruo-Yu, Liao, Bo, Liu, Jin-Xin, Wang, Hai, Song, Jia, Yao, Yin, Zhu, Li-Ping, Yu, Di and Liu, Zheng (2024). Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps. Nature Communications, 15 (1) 10413, 10413. doi: 10.1038/s41467-024-54685-1

Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps

2024

Journal Article

Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2

Lyu, Fulian, Gong, Huanle, Wu, Xiaojin, Liu, Xin, Lu, Yinghao, Wei, Xiya, Liu, Chenchen, Shen, Yaoyao, Wang, Yuhang, Lei, Lei, Chen, Jia, Ma, Shoubao, Sun, Hongjian, Yu, Di, Han, JingJing, Xu, Yang and Wu, Depei (2024). Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2. Leukemia, 39 (2), 473-481. doi: 10.1038/s41375-024-02475-5

Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2

2024

Journal Article

Interferon disrupts immune and tissue homeostasis in SLE via CXCL13

Pazhouhandeh, Mehrdad and Yu, Di (2024). Interferon disrupts immune and tissue homeostasis in SLE via CXCL13. Nature Reviews Rheumatology, 20 (12), 745-746. doi: 10.1038/s41584-024-01164-y

Interferon disrupts immune and tissue homeostasis in SLE via CXCL13

2024

Journal Article

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2024). Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 25 (9), 1764-1764. doi: 10.1038/s41590-024-01949-z

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

2024

Journal Article

The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

Patrick, Ralph, Naval-Sanchez, Marina, Deshpande, Nikita, Huang, Yifei, Zhang, Jingyu, Chen, Xiaoli, Yang, Ying, Tiwari, Kanupriya, Esmaeili, Mohammadhossein, Tran, Minh, Mohamed, Amin R., Wang, Binxu, Xia, Di, Ma, Jun, Bayliss, Jacqueline, Wong, Kahlia, Hun, Michael L., Sun, Xuan, Cao, Benjamin, Cottle, Denny L., Catterall, Tara, Barzilai-Tutsch, Hila, Troskie, Robin-Lee, Chen, Zhian, Wise, Andrea F., Saini, Sheetal, Soe, Ye Mon, Kumari, Snehlata, Sweet, Matthew J. ... Nefzger, Christian M. (2024). The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening. Cell Metabolism, 36 (8), 1858-1881.e23. doi: 10.1016/j.cmet.2024.06.006

The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

2024

Journal Article

International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis

Chen, Xin, Tsvetkov, Andrey S., Shen, Han-Ming, Isidoro, Ciro, Ktistakis, Nicholas T., Linkermann, Andreas, Koopman, Werner J. H., Simon, Hans-Uwe, Galluzzi, Lorenzo, Luo, Shouqing, Xu, Daqian, Gu, Wei, Peulen, Olivier, Cai, Qian, Rubinsztein, David C., Chi, Jen-Tsan, Zhang, Donna D., Li, Changfeng, Toyokuni, Shinya, Liu, Jinbao, Roh, Jong-Lyel, Dai, Enyong, Juhasz, Gabor, Liu, Wei, Zhang, Jianhua, Yang, Minghua, Liu, Jiao, Zhu, Ling-Qiang, Zou, Weiping ... Tang, Daolin (2024). International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis. Autophagy, 20 (6), 1213-1246. doi: 10.1080/15548627.2024.2319901

International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis

2024

Journal Article

A galectin-9–driven CD11c high decidual macrophage subset suppresses uterine vascular remodeling in preeclampsia

Li, Yanhong, Sang, Yifei, Chang, Yunjian, Xu, Chunfang, Lin, Yikong, Zhang, Yao, Chiu, Philip C.N., Yeung, William S.B., Zhou, Haisheng, Dong, Ningzheng, Xu, Ling, Chen, Jiajia, Zhao, Weijie, Liu, Lu, Yu, Di, Zang, Xingxing, Ye, Jiangfeng, Yang, Jinying, Wu, Qingyu, Li, Dajin, Wu, Ligang and Du, Meirong (2024). A galectin-9–driven CD11c high decidual macrophage subset suppresses uterine vascular remodeling in preeclampsia. Circulation, 149 (21), 1670-1688. doi: 10.1161/circulationaha.123.064391

A galectin-9–driven CD11c high decidual macrophage subset suppresses uterine vascular remodeling in preeclampsia

2024

Journal Article

Follicular T cells and the control of IgE responses

Cañete, Pablo F. and Yu, Di (2024). Follicular T cells and the control of IgE responses. Allergology International, 74 (1), 13-19. doi: 10.1016/j.alit.2024.09.007

Follicular T cells and the control of IgE responses

2023

Journal Article

Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization

Ye, Tong, Jiao, Zhouguang, Li, Xin, He, Zhanlong, Li, Yanyan, Yang, Fengmei, Zhao, Xin, Wang, Youchun, Huang, Weijin, Qin, Meng, Feng, Yingmei, Qiu, Yefeng, Yang, Wenhui, Hu, Lingfei, Hu, Yaling, Zhai, Yu, Wang, Erqiang, Yu, Di, Wang, Shuang, Yue, Hua, Wang, Yishu, Wang, Hengliang, Zhu, Li, Ma, Guanghui and Wei, Wei (2023). Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization. Nature, 624 (7992), 630-638. doi: 10.1038/s41586-023-06809-8

Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization

2023

Journal Article

Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectives

Nettelfield, Sam, Yu, Di and Cañete, Pablo F (2023). Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectives. International Immunology, 35 (12), 571-582. doi: 10.1093/intimm/dxad021

Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectives

2023

Journal Article

Low-dose IL-2 treatment rescues cognitive deficits by repairing the imbalance between Treg and Th17 cells at the middle Alzheimer’s disease stage

Yuan, Lin, Xie, Lei, Zhang, Hao, Zhang, Yu, Wei, Yunbo, Feng, Jinhong, Cui, Li, Tian, Rui, Feng, Jia, Yu, Di and Lv, Cui (2023). Low-dose IL-2 treatment rescues cognitive deficits by repairing the imbalance between Treg and Th17 cells at the middle Alzheimer’s disease stage. Journal of Neuroimmune Pharmacology, 18 (4), 674-689. doi: 10.1007/s11481-023-10090-x

Low-dose IL-2 treatment rescues cognitive deficits by repairing the imbalance between Treg and Th17 cells at the middle Alzheimer’s disease stage

2023

Journal Article

Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality

Kang, Hao, Sun, Hongjian, Yang, Yang, Tuong, Zewen K., Shu, Minglei, Wei, Yunbo, Zhang, Yu, Yu, Di and Tao, Yong (2023). Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality. Clinical and Translational Immunology, 12 (9) e1461, 1-17. doi: 10.1002/cti2.1461

Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality

2023

Journal Article

Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation

Yunis, Joseph, Short, Kirsty R. and Yu, Di (2023). Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation. Trends in Microbiology, 31 (6), 644-656. doi: 10.1016/j.tim.2022.12.008

Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation

2023

Journal Article

Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease

Chen, Titi, Cao, Qi, Wang, Ruifeng, Zheng, Guoping, Azmi, Farhana, Lee, Vincent W., Wang, Yuan Ming, Li, Hongqi, Yu, Di, Rogers, Natasha M., Alexander, Stephen I., Harris, David C.H. and Wang, Yiping (2023). Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease. Clinical Immunology, 250 109295, 1-14. doi: 10.1016/j.clim.2023.109295

Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease

2023

Journal Article

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

Chen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

2023

Journal Article

T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance

Gao, Xin, Luo, Kaiming, Wang, Diya, Wei, Yunbo, Yao, Yin, Deng, Jun, Yang, Yang, Zeng, Qunxiong, Dong, Xiaoru, Xiong, Le, Gong, Dongcheng, Lin, Lin, Pohl, Kai, Liu, Shaoling, Liu, Yu, Liu, Lu, Nguyen, Thi HO, Allen, Lilith F., Kedzierska, Katherine, Jin, Yanliang, Du, Mei-Rong, Chen, Wanping, Lu, Liangjing, Shen, Nan, Liu, Zheng, Cockburn, Ian A., Luo, Wenjing and Yu, Di (2023). T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance. eLife, 12 e82217, 1-29. doi: 10.7554/elife.82217

T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance

2023

Journal Article

Dimensionality reduction under scrutiny

Yang, Yang, Tuong, Zewen K. and Yu, Di (2023). Dimensionality reduction under scrutiny. Nature Computational Science, 3 (1), 8-9. doi: 10.1038/s43588-022-00383-1

Dimensionality reduction under scrutiny