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2021

Journal Article

PH and proton sensor GPR65 determine susceptibility to atopic dermatitis

Xie, Liang, McKenzie, Craig I., Qu, Xinyan, Mu, Yan, Wang, Quanbo, Bing, Nan, Naidoo, Karmella, Alam, Md Jahangir, Yu, Di, Gong, Fang, Ang, Caroline, Robert, Remy, Marques, Francine Z., Furlotte, Nicholas, Hinds, David, Gasser, Olivier, Xavier, Ramnik J., MacKay, Charles R., Agee, Michelle, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McCreight, Jennifer C., McIntyre, Matthew H. ... 23andMe Research Team (2021). PH and proton sensor GPR65 determine susceptibility to atopic dermatitis. Journal of Immunology, 207 (1), 101-109. doi: 10.4049/jimmunol.2001363

PH and proton sensor GPR65 determine susceptibility to atopic dermatitis

2021

Journal Article

Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

Liang, Kaili, He, Jing, Wei, Yunbo, Zeng, Qunxiong, Gong, Dongcheng, Qin, Jiahuan, Ding, Huihua, Chen, Zhian, Zhou, Ping, Niu, Peng, Chen, Qian, Ding, Chenguang, Lu, Liangjing, Chen, Xiao-Xiang, Li, Zhanguo, Shen, Nan, Yu, Di and Deng, Jun (2021). Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus. Clinical and Translational Immunology, 10 (6) e1293, e1293. doi: 10.1002/cti2.1293

Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

2021

Journal Article

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

Deng, Jun, Chen, Qian, Chen, Zhian, Liang, Kaili, Gao, Xin, Wang, Xiaohui, Makota, Fadzai V., Ong, Hong Sheng, Wan, Yanmin, Luo, Kaiming, Gong, Dongcheng, Yu, Xiang, Camuglia, Sarina, Zeng, Qunxiong, Zhou, Tao, Xue, Feng, He, Jing, Wei, Yunbo, Xiao, Fan, Ma, Jianyang, Hill, Danika L., Pierson, Wim, Nguyen, Thi H. O., Zhou, Haibo, Wang, Yan, Shen, Wei, Sun, Lingyun, Li, Zhanguo, Xia, Qiang ... Yu, Di (2021). The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses. Nature Communications, 12 (1) 3073, 3073. doi: 10.1038/s41467-021-23220-x

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

2021

Journal Article

Defective STING expression potentiates IL-13 signaling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps

Wang, Hai, Hu, Dan-Qing, Xiao, Qiao, Liu, Yi-Bo, Song, Jia, Liang, Yuxia, Ruan, Jian-Wen, Wang, Zhe-Zheng, Li, Jing-Xian, Pan, Li, Wang, Meng-Chen, Zeng, Ming, Shi, Li-Li, Xu, Kai, Ning, Qin, Zhen, Guohua, Yu, Di, Wang, De-Yun, Wenzel, Sally E. and Liu, Zheng (2021). Defective STING expression potentiates IL-13 signaling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology, 147 (5), 1692-1703. doi: 10.1016/j.jaci.2020.12.623

Defective STING expression potentiates IL-13 signaling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps

2021

Journal Article

Association of low blood arsenic exposure with level of malondialdehyde among Chinese adults aged 65 and older

Tan, Qiyue, Lv, Yuebin, Zhao, Feng, Zhou, Jinhui, Yang, Yang, Liu, Yingchun, Zhang, Mingyuan, Lu, Feng, Wei, Yuan, Chen, Xin, Zhang, Ruizhi, Chen, Chen, Wu, Bing, Zhang, Xiaochang, Li, Chengcheng, Huang, Hongyuan, Cai, Junfang, Cao, Zhaojin, Yu, Di, Ji, John S., Zhao, Shuhua and Shi, Xiaoming (2021). Association of low blood arsenic exposure with level of malondialdehyde among Chinese adults aged 65 and older. Science of the Total Environment, 758 143638, 1-8. doi: 10.1016/j.scitotenv.2020.143638

Association of low blood arsenic exposure with level of malondialdehyde among Chinese adults aged 65 and older

2021

Journal Article

Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy

Yao, Yin, Chen, Cai-Ling, Yu, Di and Liu, Zheng (2021). Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy. Allergy, 76 (2), 456-470. doi: 10.1111/all.14639

Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy

2021

Journal Article

T lymphocytes and testicular immunity: a new insight into immune regulation in testes

Gong, Jialei, Zeng, Qunxiong, Yu, Di and Duan, Yong-Gang (2021). T lymphocytes and testicular immunity: a new insight into immune regulation in testes. International Journal of Molecular Sciences, 22 (1) 57, 1-21. doi: 10.3390/ijms22010057

T lymphocytes and testicular immunity: a new insight into immune regulation in testes

2021

Journal Article

High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses

Xie, Min, Yunis, Joseph, Yao, Yin, Shi, Jing, Yang, Yang, Zhou, Pengcheng, Liang, Kaili, Wan, Yanmin, Mehdi, Ahmed, Chen, Zhian, Wang, Naiqi, Xu, Shuyun, Zhou, Min, Yu, Muqing, Wang, Ke, Tao, Yu, Zhou, Ying, Li, Xiaochen, Liu, Xiansheng, Yu, Xiao, Wei, Yunbo, Liu, Zheng, Sprent, Jonathan and Yu, Di (2021). High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses. Clinical & Translational Immunology, 10 (2) e1251, e1251. doi: 10.1002/cti2.1251

High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses

2020

Journal Article

Chlorinated flame-retardant dechlorane 602 potentiates type 2 innate lymphoid cells and exacerbates airway inflammation

Zhou, Pengcheng, Zheng, Ting, Li, Yunping, Zhang, Xin, Feng, Jinhong, Wei, Yunbo, Wang, Hao, Yao, Yin, Gong, Fang, Tian, Wenjing, Sun, Lingyun, Liu, Zheng, Zhao, Bin and Yu, Di (2020). Chlorinated flame-retardant dechlorane 602 potentiates type 2 innate lymphoid cells and exacerbates airway inflammation. Environmental Science and Technology, 55 (2) acs.est.0c03758, 1099-1109. doi: 10.1021/acs.est.0c03758

Chlorinated flame-retardant dechlorane 602 potentiates type 2 innate lymphoid cells and exacerbates airway inflammation

2020

Journal Article

Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity

Lv, Cui, Zhang, Hao, Li, Zifa, Zhang, Hao, Zhang, Yu, Li, Ronghui, Wei, Sheng and Yu, Di (2020). Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity. Cellular and Molecular Immunology, 18 (5), 1336-1338. doi: 10.1038/s41423-020-00562-y

Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity

2020

Journal Article

Stereotactic Radiation Therapy Combined With Immunotherapy Against Metastatic Melanoma: Long-Term Results of a Phase 1 Clinical Trial

Ratnayake, Gishan, Reinwald, Simone, Shackleton, Mark, Moore, Maggie, Voskoboynik, Mark, Ruben, Jeremy, van Zelm, Menno C., Yu, Di, Ward, Rachel, Smith, Robin, Haydon, Andrew and Senthi, Sashendra (2020). Stereotactic Radiation Therapy Combined With Immunotherapy Against Metastatic Melanoma: Long-Term Results of a Phase 1 Clinical Trial. International Journal of Radiation Oncology Biology Physics, 108 (1), 150-156. doi: 10.1016/j.ijrobp.2020.05.022

Stereotactic Radiation Therapy Combined With Immunotherapy Against Metastatic Melanoma: Long-Term Results of a Phase 1 Clinical Trial

2020

Journal Article

Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals

Gong, Fang, Dai, Yaping, Zheng, Ting, Cheng, Liang, Zhao, Dan, Wang, Hao, Liu, Min, Pei, Hao, Jin, Tengchuan, Yu, Di and Zhou, Pengcheng (2020). Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals. Journal of Clinical Investigation, 130 (12), 6588-6599. doi: 10.1172/jci141054

Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals

2020

Journal Article

CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis

Yao, Yin, Wang, Nan, Chen, Cai-Ling, Pan, Li, Wang, Zhi-Chao, Yunis, Joseph, Chen, Zhi-An, Zhang, Yu, Hu, Si-Tao, Xu, Xiao-Yan, Zhu, Rong-Fei, Yu, Di and Liu, Zheng (2020). CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis. Allergy, 75 (10), 1-14. doi: 10.1111/all.14288

CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis

2020

Journal Article

Prominent immune signatures of T cells are specifically associated with indolent B-cell lymphoproliferative disorders and predict prognosis

Yi, Shuhua, Zhang, Yu, Xiong, Wenjie, Chen, Weiwei, Hou, Zhaohua, Yang, Yang, Yan, Yuting, Wei, Yunbo, Cui, Rui, Wang, Huijun, Yu, Zhen, Li, Heng, Li, Zengjun, Liu, Wei, Lv, Rui, Wang, Tingyu, Ru, Kun, Zou, Dehui, Shu, Minglei, Qiu, Lugui and Yu, Di (2020). Prominent immune signatures of T cells are specifically associated with indolent B-cell lymphoproliferative disorders and predict prognosis. Clinical and Translational Immunology, 9 (1) e01105. doi: 10.1002/cti2.1105

Prominent immune signatures of T cells are specifically associated with indolent B-cell lymphoproliferative disorders and predict prognosis

2020

Journal Article

Follicular helper T cells in type 1 diabetes

Shao, Feng, Zheng, Peilin, Yu, Di, Zhou, Zhiguang and Jia, Lijing (2020). Follicular helper T cells in type 1 diabetes. The FASEB Journal, 34 (1), 30-40. doi: 10.1096/fj.201901637R

Follicular helper T cells in type 1 diabetes

2020

Journal Article

Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial

He, Jing, Zhang, Ruijun, Shao, Miao, Zhao, Xiaozhen, Miao, Miao, Chen, Jiali, Liu, Jiajia, Zhang, Xiaoying, Zhang, Xia, Jin, Yuebo, Wang, Yu, Zhang, Shilei, Zhu, Lei, Jacob, Alexander, Jia, Rulin, You, Xujie, Li, Xue, Li, Chun, Zhou, Yunshan, Yang, Yue, Ye, Hua, Liu, Yanying, Su, Yin, Shen, Nan, Alexander, Jessy, Guo, Jianping, Ambrus, Julian, Lin, Xin, Yu, Di ... Li, Zhanguo (2020). Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial. Annals of the Rheumatic Diseases, 79 (1), 141-149. doi: 10.1136/annrheumdis-2019-215396

Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial

2019

Journal Article

An optimized method to differentiate mouse follicular helper T cells in vitro

Gao, Xin, Wang, Hao, Chen, Zhian, Zhou, Pengcheng and Yu, Di (2019). An optimized method to differentiate mouse follicular helper T cells in vitro. Cellular and Molecular Immunology, 17 (7), 779-781. doi: 10.1038/s41423-019-0329-7

An optimized method to differentiate mouse follicular helper T cells in vitro

2019

Journal Article

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

Wang, Huimeng, Kjer-Nielsen, Lars, Shi, Mai, D'Souza, Criselle, Pediongco, Troi J., Cao, Hanwei, Kostenko, Lyudmila, Lim, Xin Yi, Eckle, Sidonia B. G., Meehan, Bronwyn S., Zhu, Tianyuan, Wang, Bingjie, Zhao, Zhe, Mak, Jeffrey Y. W., Fairlie, David P., Teng, Michele W. L., Rossjohn, Jamie, Yu, Di, de St Groth, Barbara Fazekas, Lovrecz, George, Lu, Louis, McCluskey, James, Strugnell, Richard A., Corbett, Alexandra J. and Chen, Zhenjun (2019). IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science Immunology, 4 (41) eaaw0402, eaaw0402. doi: 10.1126/sciimmunol.aaw0402

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

2019

Journal Article

Germinal center T-FH cells: T(w)o be or not t(w)o be, IL-6 is the answer

Zhou, Pengcheng, Liang, Kaili and Yu, Di (2019). Germinal center T-FH cells: T(w)o be or not t(w)o be, IL-6 is the answer. Science Immunology, 4 (39) eaay7668, eaay7668. doi: 10.1126/sciimmunol.aay7668

Germinal center T-FH cells: T(w)o be or not t(w)o be, IL-6 is the answer

2019

Journal Article

Combined blockade of Smad3 and JNK pathways ameliorates progressive fibrosis in folic acid nephropathy

Jiang, Mengjie, Fan, Jinjin, Qu, Xinli, Li, Songhui, Nilsson, Susan K., Sun, Yu Bo Yang, Chen, Yaping, Yu, Di, Liu, Dan, Liu, Bi-Cheng, Tang, Mingliang, Chen, Wei, Ren, Yi, Nikolic-Paterson, David J., Jiang, Xiaoyun, Li, Jinhua and Yu, Xueqing (2019). Combined blockade of Smad3 and JNK pathways ameliorates progressive fibrosis in folic acid nephropathy. Frontiers in Pharmacology, 10 (JULY) 880. doi: 10.3389/fphar.2019.00880

Combined blockade of Smad3 and JNK pathways ameliorates progressive fibrosis in folic acid nephropathy