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2026 Journal Article Modulation of the mevalonate pathway by TCR engagement regulates T follicular helper cell generation in homeostasis and autoimmunityWang, Lai, Jiang, Jiao, Yin, Haoyuan, Wu, Junhui, Su, Xiaoyu, Meng, Lingchang, Wang, Lulu, Bao, Jingjing, Li, Qilin, Wei, Yunbo, Chen, Zhian, Gong, Jialei, Cañete, Pablo F., Zheng, Meiling, Li, Wenrui, Zhou, Qiongqiong, Zhao, Ming, Yu, Di and Lu, Qianjin (2026). Modulation of the mevalonate pathway by TCR engagement regulates T follicular helper cell generation in homeostasis and autoimmunity. Immunity. doi: 10.1016/j.immuni.2026.04.009 |
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2026 Journal Article Animal models of allergen immunotherapy for allergic airway inflammationZhang, Fang, Sun, Shi-ran, Wu, Xing-liang, Ma, Jing-yi, Yu, Di, Liu, Zheng and Yao, Yin (2026). Animal models of allergen immunotherapy for allergic airway inflammation. Allergy, 81 (5), 1433-1458. doi: 10.1111/all.70323 |
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2026 Journal Article Deficiency of Setd2 in mesenchymal stem cells facilitates the progression of myelodysplastic syndrome to leukemiaWang, Rou-Jia, Li, Zi-Juan, Chen, Bing-Yi, Guo, Juan, Tao, Ying, Li, Hong-Ping, Fei, Ming-Yue, Chang, Bin-He, Zhao, Mu-Ying, Shi, Lei, Zhao, Si-Da, Zhang, Zheng, Su, Ji-Ying, Song, Lu-Xi, He, Qi, Wu, Dong, Wu, Ling-Yun, Zhang, Jia-Ying, Zong, Li-Juan, Sun, Xiao-Jian, Zhao, You-Shan, Wang, Lan and Chang, Chun-Kang (2026). Deficiency of Setd2 in mesenchymal stem cells facilitates the progression of myelodysplastic syndrome to leukemia. Molecular Medicine. doi: 10.1186/s10020-026-01492-7 |
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2026 Journal Article Feature-preserving manifold approximation and projection to analyze single-cell dataYang, Yang, Gong, Jialei, Sun, Hongjian, Choo, Amos, Mar, Jessica Cara, Wei, Yunbo, Zhang, Yu, Zhang, Wenjie, Shu, Minglei, Tuong, Zewen Kelvin and Yu, Di (2026). Feature-preserving manifold approximation and projection to analyze single-cell data. Nature Computational Science. doi: 10.1038/s43588-026-00970-6 |
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2026 Journal Article Lipid metabolism drives dietary effects on T cell ferroptosis and immunityWang, Naiqi, Chen, Zhian, Yao, Yin, Sun, Chenglong, Wei, Wei, Sun, Lei, Zhang, Hao, Li, Feng, Butcher, Daniel, Sun, Shi-Ran, Gong, Jialei, Jiang, Yingxin Celia, Qi, Yanfei, Huang, Jingxuan, Nettelfield, Sam, Liu, Rui, Zheng, Xiaoyue, Li, Chenyu, Fu, Yang, Geng, Haoyuan, Zhao, Limin, Sun, Hongjian, Yang, Yang, Ge, Yexin, Pazhouhandeh, Mehrdad, Barlow, Christopher K, Jeppe, Katherine Joanna, Yunis, Joseph, Zhu, Chen ... Yu, Di (2026). Lipid metabolism drives dietary effects on T cell ferroptosis and immunity. Nature, 653 (8113), 200-211. doi: 10.1038/s41586-026-10193-4 |
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2025 Journal Article Evaluating the therapeutic potential of tofacitinib in Sjögren’s disease: a comprehensive clinical and immunological assessmentLiu, Qinghong, Zeng, Yuqing, Xing, Xiaoyan, Huang, Bo, Feng, Ruiling, Wang, Yifan, Wang, Naidi, Zhang, Xia, Li, Yuhui, Su, Linchong, Jacob, Alexander, Ambrus, Julian L, Shen, Long, Suresh, Lakshmanan, Yu, Di, Lin, Xiang and He, Jing (2025). Evaluating the therapeutic potential of tofacitinib in Sjögren’s disease: a comprehensive clinical and immunological assessment. Rheumatology, 64 (11) keaf173, 5899-5910. doi: 10.1093/rheumatology/keaf173 |
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2025 Journal Article DNA demethylation mediated endogenous retroviruses transcription promotes aberrant T cell differentiation in systemic lupus erythematosus via RIG-I pathwayMin, Xiaoli, Yu, Yaqin, Hu, Zhi, Ouyang, Lianlian, Qiu, Yueqi, Zhao, Hongjun, Wu, Jiali, Zou, Chun, Zheng, Meiling, Yang, Shuang, Jia, Sujie, Yu, Di, Lu, Qianjin and Zhao, Ming (2025). DNA demethylation mediated endogenous retroviruses transcription promotes aberrant T cell differentiation in systemic lupus erythematosus via RIG-I pathway. eBioMedicine, 120 105934, 1-20. doi: 10.1016/j.ebiom.2025.105934 |
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2025 Journal Article GZMK+CD8+ T cells: multifaceted roles beyond cytotoxicityGuo, Cui-Lian, Wang, Chong-Shu, Wang, Xiang-Hong, Yu, Di and Liu, Zheng (2025). GZMK+CD8+ T cells: multifaceted roles beyond cytotoxicity. Trends in Immunology, 46 (8), 562-572. doi: 10.1016/j.it.2025.06.003 |
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2025 Journal Article Low-dose IL-2 reinvigorates the immunoguardians of neurodegenerative diseasesWei, Yunbo, Zhang, Yu and Yu, Di (2025). Low-dose IL-2 reinvigorates the immunoguardians of neurodegenerative diseases. Trends in Immunology, 46 (9), 608-610. doi: 10.1016/j.it.2025.07.004 |
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2025 Journal Article T-cell wars, a new hope: targeting Bcl6-expressing T cells in T1DCañete, Pablo F. and Yu, Di (2025). T-cell wars, a new hope: targeting Bcl6-expressing T cells in T1D. Diabetes, 74 (6), 867-869. doi: 10.2337/dbi24-0048 |
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2025 Journal Article Targeting inflammation with chimeric antigen receptor macrophages using a signal switchCao, Qi, Wang, Yiping, Chen, Jianwei, Wang, Ruifeng, Chen, Titi, Gloss, Brian, Read, Scott A., Wang, Xuerong, Lee, Vincent W. S., Clancy, Leighton, Rogers, Natasha M., Alexander, Stephen I., Zheng, Guoping, Yu, Di and Harris, David C. H. (2025). Targeting inflammation with chimeric antigen receptor macrophages using a signal switch. Nature Biomedical Engineering, 9 (9) 1054938, 1502-1516. doi: 10.1038/s41551-025-01387-8 |
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2025 Journal Article Inferring gene regulatory networks by hypergraph generative modelSu, Guangxin, Wang, Hanchen, Zhang, Ying, Wilkins, Marc R., Canete, Pablo F., Yu, Di, Yang, Yang and Zhang, Wenjie (2025). Inferring gene regulatory networks by hypergraph generative model. Cell Reports Methods, 5 (4) 101026, 101026. doi: 10.1016/j.crmeth.2025.101026 |
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2025 Journal Article AMPK-dependent Parkin activation suppresses macrophage antigen presentation to promote tumor progressionWang, Xinyu, Li, Yiyi, Li, Yan, Wang, Xiumei, Song, Hongrui, Wang, Yingzhao, Huang, Chunliu, Mao, Chengzhou, Wang, Lixiang, Zhong, Cheng, Yu, Di, Xia, Zijin, Feng, Yongyi, Duan, Jingjing, Liu, Yujia, Ou, Juanjuan, Luo, Congzhou, Mai, Wenhao, Hong, Hai, Cai, Weibin, Zheng, Limin, Trempe, Jean-François, Fon, Edward A., Liao, Jing, Yi, Wei and Chen, Jun (2025). AMPK-dependent Parkin activation suppresses macrophage antigen presentation to promote tumor progression. Science Advances, 11 (12) eadn8402, eadn8402. doi: 10.1126/sciadv.adn8402 |
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2025 Journal Article Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absencePazhouhandeh, Mehrdad, Sun, Hongjian and Yu, Di (2025). Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absence. Cell Research, 35 (8), 547-548. doi: 10.1038/s41422-024-01052-w |
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2025 Journal Article Follicular T cells and the control of IgE responsesCañete, Pablo F. and Yu, Di (2025). Follicular T cells and the control of IgE responses. Allergology International, 74 (1), 13-19. doi: 10.1016/j.alit.2024.09.007 |
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2024 Journal Article Dysregulation in keratinocytes drives systemic lupus erythematosus onsetTian, Jingru, Shi, Liqing, Zhang, Dingyao, Yao, Xu, Zhao, Ming, Kumari, Snehlata, Lu, Jun, Yu, Di and Lu, Qianjin (2024). Dysregulation in keratinocytes drives systemic lupus erythematosus onset. Cellular and Molecular Immunology, 22 (1) 6149, 1-14. doi: 10.1038/s41423-024-01240-z |
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2024 Journal Article IL-1β mediated fibroblast-neutrophil crosstalk promotes inflammatory environment in skin lesions of SLEChen, Xiaoyun, OuYang, Lianlian, Qian, Bao, Qiu, Yueqi, Liu, Limin, Chen, Fangqi, Jiang, Wenjuan, Zheng, Meiling, Hu, Zhi, Min, Xiaoli, Wen, Lifang, Wang, Qiaolin, Yu, Di, Jia, Sujie, Lu, Qianjin and Zhao, Ming (2024). IL-1β mediated fibroblast-neutrophil crosstalk promotes inflammatory environment in skin lesions of SLE. Clinical Immunology, 269 110396, 1-12. doi: 10.1016/j.clim.2024.110396 |
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2024 Journal Article Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polypsGuo, Cui-Lian, Wang, Chong-Shu, Wang, Zhi-Chao, Liu, Fei-Fan, Liu, Lin, Yang, Yang, Li, Xia, Guo, Bei, Lu, Ruo-Yu, Liao, Bo, Liu, Jin-Xin, Wang, Hai, Song, Jia, Yao, Yin, Zhu, Li-Ping, Yu, Di and Liu, Zheng (2024). Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps. Nature Communications, 15 (1) 10413, 1-22. doi: 10.1038/s41467-024-54685-1 |
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2024 Journal Article Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2Lyu, Fulian, Gong, Huanle, Wu, Xiaojin, Liu, Xin, Lu, Yinghao, Wei, Xiya, Liu, Chenchen, Shen, Yaoyao, Wang, Yuhang, Lei, Lei, Chen, Jia, Ma, Shoubao, Sun, Hongjian, Yu, Di, Han, JingJing, Xu, Yang and Wu, Depei (2024). Dimethyl fumarate ameliorates chronic graft-versus-host disease by inhibiting Tfh differentiation via Nrf2. Leukemia, 39 (2) 59, 473-481. doi: 10.1038/s41375-024-02475-5 |
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2024 Journal Article Interferon disrupts immune and tissue homeostasis in SLE via CXCL13Pazhouhandeh, Mehrdad and Yu, Di (2024). Interferon disrupts immune and tissue homeostasis in SLE via CXCL13. Nature Reviews Rheumatology, 20 (12), 745-746. doi: 10.1038/s41584-024-01164-y |
