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2022

Journal Article

Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps

Wang, Zhi-Chao, Yao, Yin, Chen, Cai-Ling, Guo, Cui-Lian, Ding, Hong-Xia, Song, Jia, Wang, Zhe-Zheng, Wang, Nan, Li, Xue-Li, Liao, Bo, Yang, Yang, Yu, Di and Liu, Zheng (2022). Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps. Journal of Allergy and Clinical Immunology, 149 (2), 610-623. doi: 10.1016/j.jaci.2021.06.023

Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps

2022

Journal Article

Evolution of γ chain cytokines: mechanisms, methods and applications

Antczak, Magdalena, Cañete, Pablo F., Chen, Zhian, Belle, Clémence and Yu, Di (2022). Evolution of γ chain cytokines: mechanisms, methods and applications. Computational and Structural Biotechnology Journal, 20, 4746-4755. doi: 10.1016/j.csbj.2022.08.050

Evolution of γ chain cytokines: mechanisms, methods and applications

2022

Journal Article

Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy

Chen, Zhian, Gao, Xin and Yu, Di (2022). Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy. View, 3 (1) 20200103, 20200103. doi: 10.1002/viw.20200103

Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy

2022

Book Chapter

Therapeutic modulation of T follicular helper cells by low-dose IL-2 treatment

Chen, Zhian, Liang, Kaili, Deng, Jun and Yu, Di (2022). Therapeutic modulation of T follicular helper cells by low-dose IL-2 treatment. T-follicular helper cells: methods and protocols. (pp. 255-265) New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1736-6_21

Therapeutic modulation of T follicular helper cells by low-dose IL-2 treatment

2022

Journal Article

TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis

Yao, Yin, Wang, Zhe-Zheng, Huang, Ao, Liu, Yan, Wang, Nan, Wang, Zhi-Chao, Yang, Lin, Li, Hui-Jun, Xie, Jun-Gang, Zhu, Rong-Fei, Cheng, Li-Ming, Yu, Di and Liu, Zheng (2022). TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis. Clinical and Translational Medicine, 12 (1) e717, e717. doi: 10.1002/ctm2.717

TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis

2021

Journal Article

Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis

Kang, Hao, Wei, Yunbo, Liu, Ming, Yu, Di and Tao, Yong (2021). Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis. BMC Ophthalmology, 21 (1) 193. doi: 10.1186/s12886-021-01951-1

Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis

2021

Journal Article

Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment

Wang, Shuang, Li, Feng, Ye, Tong, Wang, Jianghua, Lyu, Chengliang, Qing, Shuang, Ding, Zhaowen, Gao, Xiaoyong, Jia, Rongrong, Yu, Di, Ren, Jun, Wei, Wei and Ma, Guanghui (2021). Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment. Science Translational Medicine, 13 (615) eabb6981, eabb6981. doi: 10.1126/scitranslmed.abb6981

Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment

2021

Journal Article

Long-term outcomes in children undergoing vascular ring division: a multi-institution experience

Yu, Di, Guo, Zhangke, You, Xin, Peng, Wei, Qi, Jirong, Sun, Jian, Wu, Kaihong, Li, Xiaofeng and Mo, Xuming (2021). Long-term outcomes in children undergoing vascular ring division: a multi-institution experience. European Journal of Cardio-Thoracic Surgery, 61 (3), 605-613. doi: 10.1093/ejcts/ezab432

Long-term outcomes in children undergoing vascular ring division: a multi-institution experience

2021

Journal Article

Understand SLE heterogeneity in the era of omics, big data, and artificial intelligence

Puri, Prianka, Jiang, Simon H., Yang, Yang, Mackay, Fabienne and Yu, Di (2021). Understand SLE heterogeneity in the era of omics, big data, and artificial intelligence. Rheumatology and Autoimmunity, 1 (1), 38-49. doi: 10.1002/rai2.12010

Understand SLE heterogeneity in the era of omics, big data, and artificial intelligence

2021

Journal Article

Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus with a potential risk of deteriorating immunopathology

Zhou, Pengcheng, Chen, Jiali, He, Jing, Zheng, Ting, Yunis, Joseph, Makota, Victor, Alexandre, Yannick O., Gong, Fang, Zhang, Xia, Xie, Wuxiang, Li, Yuhui, Shao, Miao, Zhu, Yanshan, Sinclair, Jane E., Miao, Miao, Chen, Yaping, Short, Kirsty R., Mueller, Scott N., Sun, Xiaolin, Yu, Di and Li, Zhanguo (2021). Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus with a potential risk of deteriorating immunopathology. PLoS Pathogens, 17 (10) e1009858, e1009858. doi: 10.1371/journal.ppat.1009858

Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus with a potential risk of deteriorating immunopathology

2021

Journal Article

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2021). Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 22 (12), 1599-1599. doi: 10.1038/s41590-021-01063-4

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

2021

Journal Article

Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4 + T cells and ameliorates rheumatoid arthritis

Qin, Jiahuan, Huang, Xia, Wang, Naiqi, Zhou, Pengcheng, Zhang, Hao, Chen, Zhian, Liang, Kaili, Gong, Dongcheng, Zeng, Qunxiong, Niu, Peng, Chen, Anping, Yuan, Lin, Yang, Zhaohui, Su, Linchong, Shen, Nan, Deng, Jun and Yu, Di (2021). Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4 + T cells and ameliorates rheumatoid arthritis. Clinical & Translational Immunology, 10 (9) e1338, e1338. doi: 10.1002/cti2.1338

Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4 + T cells and ameliorates rheumatoid arthritis

2021

Journal Article

Huangbai liniment ameliorates skin inflammation in atopic dermatitis

Zheng, Ting, Fan, Miao, Wei, Yunbo, Feng, Jinhong, Zhou, Pengcheng, Sun, Xin, Xue, Anqi, Qin, Cheng Xue and Yu, Di (2021). Huangbai liniment ameliorates skin inflammation in atopic dermatitis. Frontiers in Pharmacology, 12 726035, 726035. doi: 10.3389/fphar.2021.726035

Huangbai liniment ameliorates skin inflammation in atopic dermatitis

2021

Journal Article

Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2021). Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 22 (9), 1127-1139. doi: 10.1038/s41590-021-00996-0

Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

2021

Journal Article

Dimensionality reduction by UMAP reinforces sample heterogeneity analysis in bulk transcriptomic data

Yang, Yang, Sun, Hongjian, Zhang, Yu, Zhang, Tiefu, Gong, Jialei, Wei, Yunbo, Duan, Yong-Gang, Shu, Minglei, Yang, Yuchen, Wu, Di and Yu, Di (2021). Dimensionality reduction by UMAP reinforces sample heterogeneity analysis in bulk transcriptomic data. Cell Reports, 36 (4) 109442, 109442. doi: 10.1016/j.celrep.2021.109442

Dimensionality reduction by UMAP reinforces sample heterogeneity analysis in bulk transcriptomic data

2021

Journal Article

Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells

Tian, Ying, Zhang, Fan, Qiu, Yefeng, Wang, Shuang, Li, Feng, Zhao, Jiawei, Pan, Chao, Tao, Yong, Yu, Di and Wei, Wei (2021). Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells. Nature Biomedical Engineering, 5 (9), 968-982. doi: 10.1038/s41551-021-00764-3

Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells

2021

Journal Article

CXCR5+CD8+ T cells shape antibody responses in vivo following protein immunisation and peripheral viral infection

Tyllis, Timona S., Fenix, Kevin A., Norton, Todd S., Kara, Ervin E., McKenzie, Duncan R., David, Shannon C., Alsharifi, Mohammed, Yu, Di, McColl, Shaun R. and Comerford, Iain (2021). CXCR5+CD8+ T cells shape antibody responses in vivo following protein immunisation and peripheral viral infection. Frontiers in Immunology, 12 626199, 626199. doi: 10.3389/fimmu.2021.626199

CXCR5+CD8+ T cells shape antibody responses in vivo following protein immunisation and peripheral viral infection

2021

Journal Article

PH and proton sensor GPR65 determine susceptibility to atopic dermatitis

Xie, Liang, McKenzie, Craig I., Qu, Xinyan, Mu, Yan, Wang, Quanbo, Bing, Nan, Naidoo, Karmella, Alam, Md Jahangir, Yu, Di, Gong, Fang, Ang, Caroline, Robert, Remy, Marques, Francine Z., Furlotte, Nicholas, Hinds, David, Gasser, Olivier, Xavier, Ramnik J., MacKay, Charles R., Agee, Michelle, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McCreight, Jennifer C., McIntyre, Matthew H. ... 23andMe Research Team (2021). PH and proton sensor GPR65 determine susceptibility to atopic dermatitis. Journal of Immunology, 207 (1), 101-109. doi: 10.4049/jimmunol.2001363

PH and proton sensor GPR65 determine susceptibility to atopic dermatitis

2021

Journal Article

Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

Liang, Kaili, He, Jing, Wei, Yunbo, Zeng, Qunxiong, Gong, Dongcheng, Qin, Jiahuan, Ding, Huihua, Chen, Zhian, Zhou, Ping, Niu, Peng, Chen, Qian, Ding, Chenguang, Lu, Liangjing, Chen, Xiao-Xiang, Li, Zhanguo, Shen, Nan, Yu, Di and Deng, Jun (2021). Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus. Clinical and Translational Immunology, 10 (6) e1293, e1293. doi: 10.1002/cti2.1293

Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

2021

Journal Article

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

Deng, Jun, Chen, Qian, Chen, Zhian, Liang, Kaili, Gao, Xin, Wang, Xiaohui, Makota, Fadzai V., Ong, Hong Sheng, Wan, Yanmin, Luo, Kaiming, Gong, Dongcheng, Yu, Xiang, Camuglia, Sarina, Zeng, Qunxiong, Zhou, Tao, Xue, Feng, He, Jing, Wei, Yunbo, Xiao, Fan, Ma, Jianyang, Hill, Danika L., Pierson, Wim, Nguyen, Thi H. O., Zhou, Haibo, Wang, Yan, Shen, Wei, Sun, Lingyun, Li, Zhanguo, Xia, Qiang ... Yu, Di (2021). The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses. Nature Communications, 12 (1) 3073, 3073. doi: 10.1038/s41467-021-23220-x

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses