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1998 Journal Article Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer termFernando, G. J. P., Stewart, T. J., Tindle, R. W. and Frazer, I. H. (1998). Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer term. Scandinavian Journal of Immunology, 47 (5), 459-465. doi: 10.1046/j.1365-3083.1998.00327.x |
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1997 Journal Article Immunomanipulative strategies for the control of human papillomavirus associated cervical diseaseTindle, Robert W. (1997). Immunomanipulative strategies for the control of human papillomavirus associated cervical disease. Immunologic Research, 16 (4), 387-400. doi: 10.1007/BF02786401 |
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1997 Journal Article Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animalDunn, Linda A., Evander, Magnus, Tindle, Robert W., Bulloch, Anne Louise, de Kluyver, Rachel L., Fernando, Germain J. P., Lambert, Paul F. and Frazer, Ian H. (1997). Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animal. Virology, 235 (1), 94-103. doi: 10.1006/viro.1997.8650 |
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1997 Journal Article E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 proteinHerd, K., Fernando, G. J. P., Dunn, L. A., Frazer, I. H., Lambert, P. and Tindle, R. W. (1997). E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein. Virology, 231 (1), 155-165. doi: 10.1006/viro.1997.8491 |
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1996 Journal Article Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoproteinZerfass-Thome, Karin, Zwerschke, Werner, Mannhardt, Boris, Tindle, Robert, Botz, Jürgen W. and Jansen-Dürr, Pidder (1996). Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein. Oncogene, 13 (11), 2323-2330. |
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1996 Journal Article Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigenLondono, L. Patricia, Chatfield, Steven, Tindle, Robert W., Herd, Karen, Gao, Xiao-Ming, Frazer, Ian and Dougan, Gordon (1996). Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen. Vaccine, 14 (6), 545-552. doi: 10.1016/0264-410X(95)00216-N |
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1996 Journal Article Human papillomavirus vaccines for cervical cancerTindle, Robert W (1996). Human papillomavirus vaccines for cervical cancer. Current Opinion in Immunology, 8 (5), 643-650. doi: 10.1016/S0952-7915(96)80080-X |
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1995 Journal Article Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccinesTindle, Robert W. and Frazer, Ian H. (1995). Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccines. Expert Opinion on Investigational Drugs, 4 (9), 783-797. doi: 10.1517/13543784.4.9.783 |
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1995 Journal Article Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin diseaseFrazer, I. H., Leippe, D. M., Dunn, L. A., Liem, A., Tindle, R. W., Fernando, G. J. P., Phelps, W. C. and Lambert, P. F. (1995). Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease. Cancer Research, 55 (12), 2635-2639. |
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1995 Journal Article T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18)Fernando, G.J.P., Tindle, R.W and Frazer, I.H. (1995). T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18). Virus Research, 36 (1), 1-13. doi: 10.1016/0168-1702(94)00101-H |
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1995 Journal Article A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvantsTindle, R. W., Croft, S., Herd, K., Malcolm, K., Geczy, A. F., Stewart, T. and Fernando, G. J. (1995). A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvants. Clinical and Experimental Immunology, 101 (2), 265-271. doi: 10.1111/j.1365-2249.1995.tb08349.x |
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1995 Journal Article Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a productionFernando, Germain J. P., Stenzel, Deborah J., Tindle, Robert W., Merza, Malik S., Morein, Bror and Frazer, Ian H. (1995). Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production. Vaccine, 13 (15), 1460-1467. doi: 10.1016/0264-410X(95)00029-Z |
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1994 Journal Article Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specificKadish, Anna S., Romney, Seymour L., Ledwidge, Richard, Tindle, Robert, Fernando, Germain J. P., Zee, Sui Y., Van Ranst, Marc A. and Burk, Robert D. (1994). Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific. Journal of General Virology, 75 (9), 2277-2284. doi: 10.1099/0022-1317-75-9-2277 |
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1994 Journal Article Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-SpecificKadish, A. S., Romney, S. L., Ledwidge, R., Tindle, R., Fernando, G. J. P., Zee, S. Y., Vanranst, M. A. and Burk, R. D. (1994). Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-Specific. Journal of General Virology, 75, 2277-2284. doi: 10.1099/0022-1317-75-9-2277 |
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1994 Journal Article Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-LinesSelvey, L. A., Dunn, L. A., Tindle, R. W., Park, D. S. and Frazer, I. H. (1994). Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-Lines. Journal of General Virology, 75 (7), 1647-1653. doi: 10.1099/0022-1317-75-7-1647 |
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1994 Journal Article Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisationTindle, R. W. and Frazer, I. H. (1994). Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisation. Current Topics in Microbiology and Immunology, 186, 217-253. doi: 10.1007/978-3-642-78487-3_12 |
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1994 Journal Article Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised miceTindle, Robert W., Herd, Karen, Londoño, Patricia, Fernando, Germain J. P., Chatfield, Steven N., Malcolm, Karen and Dougan, Gordon (1994). Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice. Virology, 200 (2), 547-557. doi: 10.1006/viro.1994.1217 |
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1993 Journal Article Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patientsStacey, Simon N., Ghosh, Anna, Bartholomew, Jennifer S., Tindle, Robert W., Stern, Peter L., Mackett, Michael and Arrand, John R. (1993) Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients. Journal of Medical Virology, 40 1: 14-21. doi:10.1002/jmv.1890400105 |
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1992 Journal Article Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controlsTindle, Robert W., Murray, Barbara, Herd, Karen, Kennedy, Lynn, O'Connor, Dan T., Fernando, Germain J. P. and Frazer, Ian H. (1992). Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls. Immunology and Infections Diseases, 2, 223-228. |
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1992 Journal Article Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cellsSMELAND, EB, FUNDERUD, S, KVALHEIM, G, GAUDERNACK, G, RASMUSSEN, AM, RUSTEN, L, WANG, MY, TINDLE, RW, BLOMHOFF, HK and EGELAND, T (1992). Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cells. Leukemia, 6 (8), 845-852. |
