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2014

Journal Article

Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study

Nikles, Catherine J., McKinlay, Lynne, Mitchell, Geoffrey K., Carmont, Sue-Ann S., Senior, Hugh E., Waugh, Mary-Clare A., Epps, Adrienne, Schluter, Philip J. and Lloyd, Owen T. (2014). Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study. Trials, 15 (54) 54, 1-11. doi: 10.1186/1745-6215-15-54

Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury: a pilot study

2013

Journal Article

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials

Nikles, Jane, Mitchell, Geoffrey K., Hardy, Janet, Agar, Meera, Senior, Hugh, Carmont, Sue-Ann, Schluter, Philip J., Good, Phillip, Vora, Rohan and Currow, David (2013). Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials. BMC Palliative Care, 12 (39) 39, 1-15. doi: 10.1186/1472-684X-12-39

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials

2013

Journal Article

Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials

Senior, Hugh E. J., McKinlay, Lynne, Nikles, Jane, Schluter, Philip J., Carmont, Sue-Ann, Waugh, Mary-Clare, Epps, Adrienne, Lloyd, Owen and Mitchell, Geoffrey K. (2013). Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials. BMC Pediatrics, 13 (1) 89, 89.1-89.7. doi: 10.1186/1471-2431-13-89

Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials

2013

Journal Article

Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol

Senior, Hugh E. J., Mitchell, Geoffrey K., Nikles, Jane, Carmont, Sue-Ann, Schluter, Philip J., Currow, David C., Vora, Rohan, Yelland, Michael J., Agar, Meera, Good, Phillip D. and Hardy, Janet R. (2013). Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol. BMC Palliative Care, 12 (1) 17, 17.1-17.6. doi: 10.1186/1472-684X-12-17

Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol

2012

Journal Article

Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol)

Punja, Salima, Shamseer, Larissa, Hartling, Lisa, Urichuk, Liana, Vandermeer, Ben, Nikles, Catherine J. and Vohra, Sunita (2012). Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol). Cochrane Database of Systematic Reviews (7). doi: 10.1002/14651858.CD009996

Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents (Protocol)

2011

Journal Article

Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care

Nikles, Jane, Mitchell, Geoffrey K., Schluter, Philip, Good, Phillip, Hardy, Janet, Rowett, Debra, Shelby-James, Tania, Vohra, Sunita and Currow, David (2011). Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care. Journal of Clinical Epidemiology, 64 (5), 471-480. doi: 10.1016/j.jclinepi.2010.05.009

Aggregating single patient (n-of-1) trials in populations where recruitment and retention was difficult: The case of palliative care

2010

Journal Article

Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer

Hardy, Janet Rea, Carmont, Sue-Ann S., O'Shea, Angela, Vora, Rohan, Schluter, Philip, Nikles, Catherine Jane and Mitchell, Geoffrey Keith (2010). Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer. Journal of Palliative Medicine, 13 (10), 1193-1197. doi: 10.1089/jpm.2010.0185

Pilot study to determine the optimal dose of methylphenidate for an n-of-1 trial for fatigue in patients with cancer

2010

Journal Article

Using N-of-1 Trials to improve patient management and save costs

Scuffham, Paul A., Nikles, Jane, Mitchell, Geoffrey K., Yelland, Michael J., Vine, Norma, Poulos, Christopher J., Pillans, Peter I., Bashford, Guy, del Mar, Chris, Schluter, Philip J. and Glasziou, Paul (2010). Using N-of-1 Trials to improve patient management and save costs. Journal of General Internal Medicine, 25 (9), 906-913. doi: 10.1007/s11606-010-1352-7

Using N-of-1 Trials to improve patient management and save costs

2010

Journal Article

Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use

Nikles, Jane, Mitchell, Geoffrey K., Clavarino, Alexandra, Yelland, Michael J. and Del Mar, Christopher B. (2010). Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use. Australian Health Review, 34 (1), 131-136. doi: 10.1071/AH09654

Stakeholders' views on the routine use of n-of-1 trials to improve clinical care and to make resource allocation decisions for drug use

2009

Journal Article

Prioritising drugs for single patient (n-of-1) trials in palliative care

Nikles, J., Mitchell, G., Walters, J., Hardy, J., Good, P., Rowett, D., Shelby-James, T. and Currow, D. (2009). Prioritising drugs for single patient (n-of-1) trials in palliative care. Palliative Medicine, 23 (7), 623-634. doi: 10.1177/0269216309106461

Prioritising drugs for single patient (n-of-1) trials in palliative care

2009

Journal Article

N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain

Yelland, Michael J., Poulos, Christopher J., Pillans, Peter I., Bashford, Guy M., Nikles, Catherine Jane, Sturtevant, Joanna M., Vine, Norma, Del Mar, Christopher, Schluter, Philip J., Tan, Meng, Chan, Jonathon, Mackenzie, Fraser and Brown, Robyn (2009). N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain. Pain Medicine, 10 (4), 754-761. doi: 10.1111/j.1526-4637.2009.00615.x

N-of-1 Randomized Trials to Assess the Efficacy of Gabapentin for Chronic Neuropathic Pain

2008

Journal Article

Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience

Scuffham, P. A., Yelland, M. J., Nikles, C. J., Pietrzak, E. and Wilkinson, D. (2008). Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience. Value in Health, 11 (1), 97-109. doi: 10.1111/j.1524-4733.2007.00218.x

Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience

2007

Journal Article

Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder

Nikles, C. Jane, Mitchell, Geoffrey K., Del Mar, Chris B., McNairn, Norma and Clavarino, Alexandra (2007). Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder. European Journal of Clinical Pharmacology, 63 (11), 985-989. doi: 10.1007/s00228-007-0361-x

Long-term changes in management following n-of-1 trials of stimulants in attention-deficit/hyperactivity disorder

2007

Journal Article

Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials

Yelland, M. J., Nikles, C. J., McNairn, N., Del Mar, C. B., Schluter, P. J. and Brown, R. M. (2007). Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials. Rheumatology, 46 (1), 135-140. doi: 10.1093/rheumatology/kel195

Celecoxib compared with sustained release paracetamol for osteoarthritis: a series of n-of-1 trials

2006

Journal Article

An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder

Nikles, C. J., Mitchell, G. K., Del Mar, C. B., Clavarino, A. and McNairn, N. (2006). An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder. Pediatrics, 117 (6), 2040-2046. doi: 10.1542/peds.2005-1328

An n-of-1 trial service in clinical practice: Testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder

2005

Journal Article

Using n-of-1 trials as a clinical tool to improve prescribing

Nikles, C. J., Clavarino, A. M. and Del Mar, C. B. (2005). Using n-of-1 trials as a clinical tool to improve prescribing. British Journal Of General Practice, 55 (512), 175-180.

Using n-of-1 trials as a clinical tool to improve prescribing

2005

Journal Article

The role of paracetamol in chronic pain: An evidence-based approach

Nikles, C. J., Yelland, M., Del Mar, C. and Wilkinson, D. (2005). The role of paracetamol in chronic pain: An evidence-based approach. American Journal of Therapeutics, 12 (1), 80-91. doi: 10.1097/00045391-200501000-00011

The role of paracetamol in chronic pain: An evidence-based approach

2003

Journal Article

Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials

Coxeter, P. D., Schluter, P. J., Eastwood, H. L., Nikles, C. J. and Glasziou, P. P. (2003). Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials. Complementary Therapies In Medicine, 11 (4), 215-222. doi: 10.1016/S0965-2299(03)00122-5

Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-I trials

2001

Journal Article

Bias Influencing Maternal Reports of Child Behaviour and Emotional State

Najman, J. M., Williams, G. M., Nikles, J., Spence, S., Bor, W., O'Callaghan, M., Le Brocque, R., Andersen, M. J. and Shuttlewood, G. J. (2001). Bias Influencing Maternal Reports of Child Behaviour and Emotional State. Social Psychiatry and Psychiatric Epidemiology, 36 (4), 186-194. doi: 10.1007/s001270170062

Bias Influencing Maternal Reports of Child Behaviour and Emotional State

2000

Journal Article

Preliminary experiences with a single-patient trials service in general practice

Nikles, C. J., Glasziou, P. P., Del Mar, C. B., Duggan, C. M., Clavarino, A. M. and Yelland, M. J. (2000). Preliminary experiences with a single-patient trials service in general practice. Medical Journal of Australia, 173 (2), 100-103. doi: 10.5694/j.1326-5377.2000.tb139254.x

Preliminary experiences with a single-patient trials service in general practice