Overview
Background
A/Prof Mark D. Chatfield is a highly experienced statistician in the UQ Clinical Trials Centre and collaborates with researchers across the Faculty of Health, Medicine and Behavioural Sciences.
In collaboration with health and medical researchers, he has published >200 times in academic journals. He has been an investigator on 30 NHMRC/MRFF funded (>$57M) studies (mostly clinical trials). He has >20 years of experience as a biostatistician in Australia (Brisbane, Darwin, Sydney) and the UK (Cambridge, 2002-2009). He has co-supervised 8 PhD students to completion.
He plays an active role in the Australian Clinical Trials Alliance Statistics in Trials Interest Group.
Stata users around the world enjoy using his table1_mc and blandaltman commands.
He is an Honorary Fellow (Associate Professor) with Menzies School of Health Research.
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor of Arts, University of Oxford
- Masters (Coursework), University of Southampton
- Masters (Coursework), University of Oxford
Research interests
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Clinical trials
Mark has been involved with a plethora of trials of various designs in a broad range of fields. He makes significant contributions to funding applications, trial design, analysis, presentation and interpretation. To date, he has published on 39 randomised trials (protocol and/or results paper). He is involved with methodological research into cluster randomised trials as well as sample size calculations.
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Meta-analysis
Mark has been involved with a variety of meta-analyses. He has found a novel way to interpret the heterogeneity parameter, tau, in random-effects meta-analysis of ratios. That said, he advocates for the reporting of tau, or exp(tau) for ratios, rather than tau^2 as it is most easily understood.
Works
Search Professor Mark Chatfield’s works on UQ eSpace
2012
Journal Article
Electroacupuncture for nausea, vomiting, and myelosuppression in women receiving adjuvant chemotherapy for early breast cancer: a randomized controlled pilot trial
Beith, Jane M., Oh, Byeongsang, Chatfield, Mark D., Davis, Esther and Venkateswaran, Ramya (2012). Electroacupuncture for nausea, vomiting, and myelosuppression in women receiving adjuvant chemotherapy for early breast cancer: a randomized controlled pilot trial. Medical Acupuncture, 24 (4), 241-248. doi: 10.1089/acu.2012.0876
2012
Journal Article
Dietary iron is associated with memory in midlife: longitudinal cohort study
Rickard, Anna P., Chatfield, Mark D., Powell, Jonathan J., Stephen, Alison M. and Richards, Marcus (2012). Dietary iron is associated with memory in midlife: longitudinal cohort study. Journal of Pharmacy and Nutrition Sciences, 2 (1), 57-62. doi: 10.6000/1927-5951.2012.02.01.8
2012
Journal Article
Definitive radiotherapy or chemoradiotherapy in the treatment of Merkel cell carcinoma
Sundaresan, P., Hruby, G., Hamilton, A., Hong, A., Boyer, M., Chatfield, M. and Thompson, J. F. (2012). Definitive radiotherapy or chemoradiotherapy in the treatment of Merkel cell carcinoma. Clinical Oncology, 24 (9), E131-E136. doi: 10.1016/j.clon.2012.04.007
2012
Journal Article
Antibiotics for bronchiectasis exacerbations in children: Rationale and study protocol for a randomised placebo-controlled trial
Chang, Anne B., Grimwood, Keith, Robertson, Colin F., Wilson, Andrew C., van Asperen, Peter P., O'Grady, Kerry-Ann F., Sloots, Theo P., Torzillo, Paul J., Bailey, Emily J., Mccallum, Gabrielle B., Masters, Ian B., Byrnes, Catherine .A, Buntain, Helen M., Morris, Peter S., Mackay, Ian M. and Chatfield, Mark D. (2012). Antibiotics for bronchiectasis exacerbations in children: Rationale and study protocol for a randomised placebo-controlled trial. Trials, 13 (156) 156, 156-1-156-9. doi: 10.1186/1745-6215-13-156
2012
Journal Article
High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy
Savdie, Richard, Horvath, Lisa G., Benito, Ruth Pe, Rasiah, Krishan K., Haynes, Anne-Maree, Chatfield, Mark, Stricker, Phillip D., Turner, Jennifer J., Delprado, Warwick, Henshall, Susan M., Sutherland, Robert L. and Kench, James G. (2012). High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy. BJU International, 109 (12), 1794-1800. doi: 10.1111/j.1464-410X.2011.10572.x
2012
Conference Publication
Progression-free survival (PFS) as a surrogate end point for overall survival (OS) in first-line treatment of advanced epithelial ovarian cancer (EOC)
Sjoquist, Katrin Marie, Lee, Chee, Lord, Sally, Chatfield, Mark D., Friedlander, Michael, Simes, John and Marschner, Ian (2012). Progression-free survival (PFS) as a surrogate end point for overall survival (OS) in first-line treatment of advanced epithelial ovarian cancer (EOC). 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 01-06, 2012. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.
2012
Conference Publication
EVERSUN: A phase II trial of everolimus alternating with sunitinib as first-line therapy for advanced renal cell carcinoma (RCC) (ANZUP trial 0901)
Davis, Ian D., Gebski, Val, Chatfield, Mark D., Grimison, Peter S., Kannourakis, George, Boland, Amy L., Thompson, Jennifer and Stockler, Martin R. (2012). EVERSUN: A phase II trial of everolimus alternating with sunitinib as first-line therapy for advanced renal cell carcinoma (RCC) (ANZUP trial 0901). 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 01-06, 2012. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.
2012
Journal Article
HDR brachytherapy combined with external beam radiation for localised prostate cancer: early experience from the Sydney Cancer Centre
Whalley, Deborah, Patanjali, Nitya, Jackson, Michael, Lovett, Aimee, Chatfield, Mark and Hruby, George (2012). HDR brachytherapy combined with external beam radiation for localised prostate cancer: early experience from the Sydney Cancer Centre. Journal of Medical Imaging and Radiation Oncology, 56 (2), 220-226. doi: 10.1111/j.1754-9485.2012.02358.x
2012
Conference Publication
Accelerated BEP for metastatic germ cell tumors: Combined analysis of Australian and UK phase I/II trials
Grimison, Peter S., Chatfield, Mark D., Mazhar, Danish, Toner, Guy C., Chester, John D., Stockler, Martin R., Stark, Daniel P., Thomson, Damien B., Shamash, Jonathan, Friedlander, Michael, White, Jeff, Gebski, Val, Wason, James, Boland, Amy L., Rimmer, Yvonne L., McDonald, Angus, Gurney, Howard, Rosenthal, Mark, Singhal, Nimit and Williams, Michael V. (2012). Accelerated BEP for metastatic germ cell tumors: Combined analysis of Australian and UK phase I/II trials. 48th Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, Il United States, 01-06 June 2012. Alexandria, VA United States: American Society of Clinical Oncology.
2011
Journal Article
Low Calretinin Expression and High Neutrophil-To-Lymphocyte Ratio Are Poor Prognostic Factors in Patients with Malignant Mesothelioma Undergoing Extrapleural Pneumonectomy
Kao, Steven Chuan-Hao, Klebe, Sonja, Henderson, Douglas W., Reid, Glen, Chatfield, Mark, Armstrong, Nicola J., Yan, Tristan D., Vardy, Janette, Clarke, Stephen, van Zandwijk, Nico and McCaughan, Brian (2011). Low Calretinin Expression and High Neutrophil-To-Lymphocyte Ratio Are Poor Prognostic Factors in Patients with Malignant Mesothelioma Undergoing Extrapleural Pneumonectomy. Journal of Thoracic Oncology, 6 (11), 1923-1929. doi: 10.1097/JTO.0b013e31822a3740
2011
Conference Publication
Factors Affecting Time From Surgery to Adjuvant Chemotherapy for Early Breast Cancer in a Rural and Urban Medical Oncology Unit - a Retrospective Cohort Study
Fox, P. N., Chatfield, M. D., Beith, J., Turley, K. and Grimison, P. S. (2011). Factors Affecting Time From Surgery to Adjuvant Chemotherapy for Early Breast Cancer in a Rural and Urban Medical Oncology Unit - a Retrospective Cohort Study. European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care, Stockholm Sweden, Sep 23-27, 2011. OXFORD: ELSEVIER SCI LTD. doi: 10.1016/S0959-8049(11)71216-3
2011
Conference Publication
Patterns of Care for Stage 1 Testicular Cancer in Australia in 2010
Houghton, B., Stockler, M., Chatfield, M. D., Toner, G., Davis, I. D. and Grimison, P. S. (2011). Patterns of Care for Stage 1 Testicular Cancer in Australia in 2010. European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care, Stockholm Sweden, Sep 23-27, 2011. OXFORD: ELSEVIER SCI LTD.
2011
Conference Publication
PROGNOSTIC FACTORS IN MALIGNANT PLEURAL MESOTHELIOMA (MPM) IN A COHORT OF PATIENTS COMPENSATED BY THE DUST DISEASES BOARD
Kao, Steven C., Clarke, Stephen, Chatfield, Mark, Corte, Peter, Clarke, Christopher, Vardy, Janette and Van Zandwijk, Nico (2011). PROGNOSTIC FACTORS IN MALIGNANT PLEURAL MESOTHELIOMA (MPM) IN A COHORT OF PATIENTS COMPENSATED BY THE DUST DISEASES BOARD. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2011
Conference Publication
CALRETININ EXPRESSION IMPROVES THE PREDICTIVE ACCURACY IN SURVIVAL IN PATIENTS WITH MALIGNANT PLEURAL MESOTHELIOMA (MPM) UNDERGOING EXTRAPLEURAL PNEUMONECTOMY (EPP)
Kao, Steven C., Klebe, Sonja, Henderson, Douglas W., Reid, Glen, Chatfield, Mark, Armstrong, Nicola, Yan, Tristan, Vardy, Janette, Clarke, Stephen, Van Zandwijk, Nico and Mccaughan, Brian (2011). CALRETININ EXPRESSION IMPROVES THE PREDICTIVE ACCURACY IN SURVIVAL IN PATIENTS WITH MALIGNANT PLEURAL MESOTHELIOMA (MPM) UNDERGOING EXTRAPLEURAL PNEUMONECTOMY (EPP). PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2011
Conference Publication
MARKERS OF PROGNOSIS IN RESECTED STAGE IB NON-SMALL CELL LUNG CANCER (NSCLC)
Yip, Po Yee, Cooper, Wendy, Mahar, Annabelle, Kench, James, Kohonen-Corish, Maija R. J., Chatfield, Mark, Boulghourjian, Alice, Kennedy, Catherine W., Mccaughan, Brian, Boyer, Michael and Horvath, Lisa (2011). MARKERS OF PROGNOSIS IN RESECTED STAGE IB NON-SMALL CELL LUNG CANCER (NSCLC). PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2011
Conference Publication
Accelerated BEP for advanced germ cell tumors: An Australian multicenter phase I/II trial
Grimison, P. S., Thomson, D. B., Stockler, M. R., Chatfield, M. D., Friedlander, M., Gebski, V., Boland, A. L., Houghton, B. B., Gurney, H., Rosenthal, M., Singhal, N., Kichenadasse, G., Wong, S. S., Lewis, C. R., Vasey, P. A. and Toner, G. C. (2011). Accelerated BEP for advanced germ cell tumors: An Australian multicenter phase I/II trial. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/jco.2011.29.15_suppl.4561
2011
Conference Publication
Morphologic and immunohistochemical (IHC) changes in metastatic melanoma (MM) tissue and associations with clinical outcome in patients (pts) on BRAF inhibitors (BRAFi)
Long, G. V., Wilmott, J. S., Howle, J. R., Chatfield, M. D., Tembe, V., Thompson, J. F., Hersey, P., Mann, G. J., McArthur, G. A., Rizos, H., Young, R. J., Scurr, L. L., Sharma, R. N., Kefford, R. F. and Scolyer, R. A. (2011). Morphologic and immunohistochemical (IHC) changes in metastatic melanoma (MM) tissue and associations with clinical outcome in patients (pts) on BRAF inhibitors (BRAFi). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/jco.2011.29.15_suppl.8542
2011
Conference Publication
BRAF mutation by age-decade and body mass index in metastatic melanoma
Menzies, A. M., Visintin, L., Chatfield, M. D., Carlino, M. S., Howle, J. R., Scolyer, R. A., Thompson, J. F., Kefford, R. F. and Long, G. V. (2011). BRAF mutation by age-decade and body mass index in metastatic melanoma. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.
2011
Conference Publication
Cytokines' profiles to predict chemotherapy outcome in castration-resistant prostate cancer (CRPC)
Mahon, K. L., Chatfield, M. D., Lee-Ng, M., Breit, S. N., Brown, D. A., Molloy, M. P., Marx, G. M., Pavlakis, N., Boyer, M. J., Stockler, M. R., Wykes, R., Henshall, S. M., Sutherland, R. L. and Horvath, L. (2011). Cytokines' profiles to predict chemotherapy outcome in castration-resistant prostate cancer (CRPC). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/jco.2011.29.15_suppl.4598
2011
Conference Publication
A study of <i>methylated glutathione s-transferase 1 (mGSTP1)</i> as a potential plasma epigenetic marker of response to chemotherapy and prognosis in men with castration-resistant prostate cancer (CRPC)
Horvath, L., Mahon, K. L., Qu, W., Devaney, J., Chatfield, M. D., Paul, C., Wykes, R., Boyer, M. J., Stockler, M. R., Marx, G. M., Sutherland, R. L. and Clark, S. J. (2011). A study of methylated glutathione s-transferase 1 (mGSTP1) as a potential plasma epigenetic marker of response to chemotherapy and prognosis in men with castration-resistant prostate cancer (CRPC). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/jco.2011.29.15_suppl.4603
Funding
Current funding
Past funding
Supervision
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Novel trial design in evaluation of antibiotics.
Associate Advisor
Other advisors: Dr Patrick Harris
Completed supervision
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2026
Doctor Philosophy
Epidemiology and clinical outcomes of gram-negative bloodstream infections in children
Associate Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Associate Professor Adam Irwin
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2025
Doctor Philosophy
Treatment Strategies for Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-producing Enterobacterales
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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2025
Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
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2024
Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Media
Enquiries
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