Overview
Background
A/Prof Mark D. Chatfield is a highly experienced statistician in the UQ Clinical Trials Centre and collaborates with researchers across the Faculty of Health, Medicine and Behavioural Sciences.
In collaboration with health and medical researchers, he has published >200 times in academic journals. He has been an investigator on 30 NHMRC/MRFF funded (>$57M) studies (mostly clinical trials). He has >20 years of experience as a biostatistician in Australia (Brisbane, Darwin, Sydney) and the UK (Cambridge, 2002-2009). He has co-supervised 7 PhD students to completion, and is currently an advisor to 2 PhD students.
He plays an active role in the Australian Clinical Trials Alliance Statistics in Trials Interest Group.
Stata users around the world enjoy using his table1_mc command.
He is an Honorary Fellow (Associate Professor) with Menzies School of Health Research.
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor of Arts, University of Oxford
- Masters (Coursework), University of Southampton
- Masters (Coursework), University of Oxford
Research interests
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Clinical trials
Mark has been involved with a plethora of trials of various designs in a broad range of fields. He makes considered, significant contributions to funding applications, trial design, analysis, presentation and interpretation. To date, he has published on 39 randomised trials (protocol and/or results paper). He is involved with methodological research into cluster randomised trials as well as sample size calculations and the anticipated width of 95% confidence intervals.
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Meta-analysis
Mark has been involved with a variety of meta-analyses. He has found a novel way to interpret the heterogeneity parameter, tau, in random-effects meta-analysis of ratios. He advocates for the reporting of tau (or exp(tau) for ratios) rather than tau^2 as it better facilitates understanding of heterogeneity estimates.
Works
Search Professor Mark Chatfield’s works on UQ eSpace
2013
Journal Article
Dietary fortificant iron intake is negatively associated with quality of life in patients with mildly active inflammatory bowel disease
Powell, Jonathan J., Cook, William B., Hutchinson, Carol, Tolkien, Zoe, Chatfield, Mark, Pereira, Dora I. A. and Lomer, Miranda C. E. (2013). Dietary fortificant iron intake is negatively associated with quality of life in patients with mildly active inflammatory bowel disease. Nutrition & Metabolism, 10 (1) 9. doi: 10.1186/1743-7075-10-9
2013
Journal Article
Human papillomavirus modifies the prognostic significance of T stage and possibly N stage in tonsillar cancer
Hong, A. M., Martin, A., Armstrong, B. K., Lee, C. S., Jones, D., Chatfield, M. D., Zhang, M., Harnett, G., Clark, J., Elliott, M., Milross, C., Smee, R., Corry, J., Liu, C., Porceddu, S., Vaska, K., Veness, M., Morgan, G., Fogarty, G., Veivers, D., Rees, G. and Rose, B. (2013). Human papillomavirus modifies the prognostic significance of T stage and possibly N stage in tonsillar cancer. Annals of Oncology, 24 (1) mds205, 215-219. doi: 10.1093/annonc/mds205
2013
Journal Article
Validation of prognostic factors in malignant pleural mesothelioma: a retrospective analysis of data from patients seeking compensation from the New South Wales dust diseases board
Kao, Steven C., Vardy, Janette, Chatfield, Mark, Corte, Peter, Pavlakis, Nick, Clarke, Christopher, van Zandwijk, Nico and Clarke, Stephen (2013). Validation of prognostic factors in malignant pleural mesothelioma: a retrospective analysis of data from patients seeking compensation from the New South Wales dust diseases board. Clinical Lung Cancer, 14 (1), 70-77. doi: 10.1016/j.cllc.2012.03.011
2013
Conference Publication
A single dose of azithromcyin did not improve clinical outcomes in children ≤ 18 months hospitalized with acute bronchiolitis: a double-blind, placebo-controlled randomized trial
Mccallum, G., Morris, P. S., Chatfield, M. D., Maclennan, C., White, A., Versteegh, L., Wilson, C., Jacobsen, N. and Chang, A. B. (2013). A single dose of azithromcyin did not improve clinical outcomes in children ≤ 18 months hospitalized with acute bronchiolitis: a double-blind, placebo-controlled randomized trial. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12046
2012
Journal Article
Electroacupuncture for nausea, vomiting, and myelosuppression in women receiving adjuvant chemotherapy for early breast cancer: a randomized controlled pilot trial
Beith, Jane M., Oh, Byeongsang, Chatfield, Mark D., Davis, Esther and Venkateswaran, Ramya (2012). Electroacupuncture for nausea, vomiting, and myelosuppression in women receiving adjuvant chemotherapy for early breast cancer: a randomized controlled pilot trial. Medical Acupuncture, 24 (4), 241-248. doi: 10.1089/acu.2012.0876
2012
Journal Article
Dietary iron is associated with memory in midlife: longitudinal cohort study
Rickard, Anna P., Chatfield, Mark D., Powell, Jonathan J., Stephen, Alison M. and Richards, Marcus (2012). Dietary iron is associated with memory in midlife: longitudinal cohort study. Journal of Pharmacy and Nutrition Sciences, 2 (1), 57-62. doi: 10.6000/1927-5951.2012.02.01.8
2012
Journal Article
Definitive radiotherapy or chemoradiotherapy in the treatment of Merkel cell carcinoma
Sundaresan, P., Hruby, G., Hamilton, A., Hong, A., Boyer, M., Chatfield, M. and Thompson, J. F. (2012). Definitive radiotherapy or chemoradiotherapy in the treatment of Merkel cell carcinoma. Clinical Oncology, 24 (9), E131-E136. doi: 10.1016/j.clon.2012.04.007
2012
Journal Article
Antibiotics for bronchiectasis exacerbations in children: Rationale and study protocol for a randomised placebo-controlled trial
Chang, Anne B., Grimwood, Keith, Robertson, Colin F., Wilson, Andrew C., van Asperen, Peter P., O'Grady, Kerry-Ann F., Sloots, Theo P., Torzillo, Paul J., Bailey, Emily J., Mccallum, Gabrielle B., Masters, Ian B., Byrnes, Catherine .A, Buntain, Helen M., Morris, Peter S., Mackay, Ian M. and Chatfield, Mark D. (2012). Antibiotics for bronchiectasis exacerbations in children: Rationale and study protocol for a randomised placebo-controlled trial. Trials, 13 (156) 156, 156-1-156-9. doi: 10.1186/1745-6215-13-156
2012
Journal Article
High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy
Savdie, Richard, Horvath, Lisa G., Benito, Ruth Pe, Rasiah, Krishan K., Haynes, Anne-Maree, Chatfield, Mark, Stricker, Phillip D., Turner, Jennifer J., Delprado, Warwick, Henshall, Susan M., Sutherland, Robert L. and Kench, James G. (2012). High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy. BJU International, 109 (12), 1794-1800. doi: 10.1111/j.1464-410X.2011.10572.x
2012
Conference Publication
Progression-free survival (PFS) as a surrogate end point for overall survival (OS) in first-line treatment of advanced epithelial ovarian cancer (EOC)
Sjoquist, Katrin Marie, Lee, Chee, Lord, Sally, Chatfield, Mark D., Friedlander, Michael, Simes, John and Marschner, Ian (2012). Progression-free survival (PFS) as a surrogate end point for overall survival (OS) in first-line treatment of advanced epithelial ovarian cancer (EOC). 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 01-06, 2012. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.
2012
Conference Publication
EVERSUN: A phase II trial of everolimus alternating with sunitinib as first-line therapy for advanced renal cell carcinoma (RCC) (ANZUP trial 0901)
Davis, Ian D., Gebski, Val, Chatfield, Mark D., Grimison, Peter S., Kannourakis, George, Boland, Amy L., Thompson, Jennifer and Stockler, Martin R. (2012). EVERSUN: A phase II trial of everolimus alternating with sunitinib as first-line therapy for advanced renal cell carcinoma (RCC) (ANZUP trial 0901). 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 01-06, 2012. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.
2012
Journal Article
HDR brachytherapy combined with external beam radiation for localised prostate cancer: early experience from the Sydney Cancer Centre
Whalley, Deborah, Patanjali, Nitya, Jackson, Michael, Lovett, Aimee, Chatfield, Mark and Hruby, George (2012). HDR brachytherapy combined with external beam radiation for localised prostate cancer: early experience from the Sydney Cancer Centre. Journal of Medical Imaging and Radiation Oncology, 56 (2), 220-226. doi: 10.1111/j.1754-9485.2012.02358.x
2012
Conference Publication
Accelerated BEP for metastatic germ cell tumors: Combined analysis of Australian and UK phase I/II trials
Grimison, Peter S., Chatfield, Mark D., Mazhar, Danish, Toner, Guy C., Chester, John D., Stockler, Martin R., Stark, Daniel P., Thomson, Damien B., Shamash, Jonathan, Friedlander, Michael, White, Jeff, Gebski, Val, Wason, James, Boland, Amy L., Rimmer, Yvonne L., McDonald, Angus, Gurney, Howard, Rosenthal, Mark, Singhal, Nimit and Williams, Michael V. (2012). Accelerated BEP for metastatic germ cell tumors: Combined analysis of Australian and UK phase I/II trials. 48th Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, Il United States, 01-06 June 2012. Alexandria, VA United States: American Society of Clinical Oncology.
2011
Journal Article
Low Calretinin Expression and High Neutrophil-To-Lymphocyte Ratio Are Poor Prognostic Factors in Patients with Malignant Mesothelioma Undergoing Extrapleural Pneumonectomy
Kao, Steven Chuan-Hao, Klebe, Sonja, Henderson, Douglas W., Reid, Glen, Chatfield, Mark, Armstrong, Nicola J., Yan, Tristan D., Vardy, Janette, Clarke, Stephen, van Zandwijk, Nico and McCaughan, Brian (2011). Low Calretinin Expression and High Neutrophil-To-Lymphocyte Ratio Are Poor Prognostic Factors in Patients with Malignant Mesothelioma Undergoing Extrapleural Pneumonectomy. Journal of Thoracic Oncology, 6 (11), 1923-1929. doi: 10.1097/JTO.0b013e31822a3740
2011
Conference Publication
PROGNOSTIC FACTORS IN MALIGNANT PLEURAL MESOTHELIOMA (MPM) IN A COHORT OF PATIENTS COMPENSATED BY THE DUST DISEASES BOARD
Kao, Steven C., Clarke, Stephen, Chatfield, Mark, Corte, Peter, Clarke, Christopher, Vardy, Janette and Van Zandwijk, Nico (2011). PROGNOSTIC FACTORS IN MALIGNANT PLEURAL MESOTHELIOMA (MPM) IN A COHORT OF PATIENTS COMPENSATED BY THE DUST DISEASES BOARD. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2011
Conference Publication
CALRETININ EXPRESSION IMPROVES THE PREDICTIVE ACCURACY IN SURVIVAL IN PATIENTS WITH MALIGNANT PLEURAL MESOTHELIOMA (MPM) UNDERGOING EXTRAPLEURAL PNEUMONECTOMY (EPP)
Kao, Steven C., Klebe, Sonja, Henderson, Douglas W., Reid, Glen, Chatfield, Mark, Armstrong, Nicola, Yan, Tristan, Vardy, Janette, Clarke, Stephen, Van Zandwijk, Nico and Mccaughan, Brian (2011). CALRETININ EXPRESSION IMPROVES THE PREDICTIVE ACCURACY IN SURVIVAL IN PATIENTS WITH MALIGNANT PLEURAL MESOTHELIOMA (MPM) UNDERGOING EXTRAPLEURAL PNEUMONECTOMY (EPP). PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2011
Conference Publication
MARKERS OF PROGNOSIS IN RESECTED STAGE IB NON-SMALL CELL LUNG CANCER (NSCLC)
Yip, Po Yee, Cooper, Wendy, Mahar, Annabelle, Kench, James, Kohonen-Corish, Maija R. J., Chatfield, Mark, Boulghourjian, Alice, Kennedy, Catherine W., Mccaughan, Brian, Boyer, Michael and Horvath, Lisa (2011). MARKERS OF PROGNOSIS IN RESECTED STAGE IB NON-SMALL CELL LUNG CANCER (NSCLC). PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2011
Journal Article
Clinical validation study to measure the performance of the nerve root sedimentation sign for the diagnosis of lumbar spinal stenosis
Staub, Lukas P., Barz, Thomas, Melloh, Markus, Lord, Sarah J., Chatfield, Mark and Bossuyt, Patrick M. (2011). Clinical validation study to measure the performance of the nerve root sedimentation sign for the diagnosis of lumbar spinal stenosis. Contemporary Clinical Trials, 32 (3), 470-474. doi: 10.1016/j.cct.2011.01.015
2011
Journal Article
The reliability of assigning individuals to cognitive states using the Mini Mental-State Examination: a population-based prospective cohort study
Marioni, Riccardo E., Chatfield, Mark, Brayne, Carol, Matthews, Fiona E. and Medical Research Council Cognitive Function and Ageing Study Group (2011). The reliability of assigning individuals to cognitive states using the Mini Mental-State Examination: a population-based prospective cohort study. BMC Medical Research Methodology, 11 (1) 127, 127.1-127.6. doi: 10.1186/1471-2288-11-127
2010
Journal Article
Validity of a New Abdominal Bioelectrical Impedance Device to Measure Abdominal and Visceral Fat: Comparison With MRI
Browning, Lucy M., Mugridge, Owen, Chatfield, Mark D., Dixon, Adrian K., Aitken, Sri W., Joubert, Ilse, Prentice, Andrew M. and Jebb, Susan A. (2010). Validity of a New Abdominal Bioelectrical Impedance Device to Measure Abdominal and Visceral Fat: Comparison With MRI. Obesity, 18 (12), 2385-2391. doi: 10.1038/oby.2010.71
Funding
Current funding
Past funding
Supervision
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Novel trial design in evaluation of antibiotics.
Associate Advisor
Other advisors: Dr Patrick Harris
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Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Associate Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Associate Professor Adam Irwin
Completed supervision
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2025
Doctor Philosophy
Treatment Strategies for Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-producing Enterobacterales
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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2025
Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
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2024
Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Media
Enquiries
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