
Overview
Background
A/Prof Mark D. Chatfield is a highly experienced statistician and clinical trialist working at the UQ Clinical Trials Centre.
In collaboration with health and medical researchers, he has published >200 times in academic journals. He has been an investigator on 28 NHMRC/MRFF funded (>$56M) studies (mostly clinical trials). He has co-supervised 5 PhD students to completion, and is currently an advisor to 4 PhD students. He has over 20 years of experience as a biostatistician in Australia (Brisbane | Darwin | Sydney) and the UK (Cambridge, 2002-2009).
He plays an active role in the Australian Clinical Trials Alliance Statistics in Trials Interest Group.
Stata users around the world enjoy using his table1_mc command.
He is an Honorary Fellow (Associate Professor) with Menzies School of Health Research.
Availability
- Mr Mark Chatfield is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Arts, University of Oxford
- Masters (Coursework), University of Southampton
- Masters (Coursework), University of Oxford
Research interests
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Randomised Controlled Trials (RCTs)
Mark has been involved with a plethora of trials of various designs in a broad range of fields. He makes considered, significant contributions to funding applications, trial design, analysis, presentation and interpretation. To date, he has published on 39 randomised trials (protocol and/or results paper). He is involved with methodological research into cluster randomised trials as well as sample size calculations and the anticipated width of 95% confidence intervals.
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Ready interpretation of log-scale ouput
Ready interpretation of log-scale ouput such as SD(ln Y), Bias(ln estimator). Symmetric percentage differences such as 100(A – B)/0.5(A + B)% or 100(lnA – lnB)%, Bland-Altman plots, and the summarising, modelling and plotting of lognormal data.
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Meta analysis
Mark has been involved with a variety of meta-analyses. He has found a novel way to interpret the heterogeneity parameter, tau, in random-effects meta-analysis of various ratios (e.g. odds ratio, ratio of means etc). He advocates for the reporting of tau (or exp(tau) for ratio measures) rather than tau^2 as it makes appreciating heterogeneity easier.
Works
Search Professor Mark Chatfield’s works on UQ eSpace
2015
Journal Article
Three-weekly doses of azithromycin for indigenous infants hospitalized with bronchiolitis: a multicentre, randomized, placebo-controlled trial
McCallum, Gabrielle B., Morris, Peter S., Grimwood, Keith, Maclennan, Carolyn, White, Andrew V., Chatfield, Mark D., Sloots, Theo P., Mackay, Ian M., Smith-Vaughan, Heidi, McKay, Clare C., Versteegh, Lesley A., Jacobsen, Nerida, Mobberley, Charmaine, Byrnes, Catherine A. and Chang, Anne B. (2015). Three-weekly doses of azithromycin for indigenous infants hospitalized with bronchiolitis: a multicentre, randomized, placebo-controlled trial. Frontiers in Pediatrics, 3 32, 32.1-32.9. doi: 10.3389/fped.2015.00032
2015
Journal Article
Survival of Indigenous Australians receiving renal replacement therapy: closing the gap?
Lawton, Paul D., Cunningham, Joan, Zhao, Yuejen, Gray, Nicholas A., Chatfield, Mark D., Baade, Peter D., Murali, Karumathil and Jose, Matthew D. (2015). Survival of Indigenous Australians receiving renal replacement therapy: closing the gap?. Medical Journal of Australia, 202 (4), 200-204. doi: 10.5694/mja14.00664
2015
Journal Article
What Drives the Occurrence of the Melioidosis Bacterium Burkholderia pseudomallei in Domestic Gardens?
Kaestli, Mirjam, Harrington, Glenda, Mayo, Mark, Chatfield, Mark D., Harrington, Ian, Hill, Audrey, Munksgaard, Niels, Gibb, Karen and Currie, Bart J. (2015). What Drives the Occurrence of the Melioidosis Bacterium Burkholderia pseudomallei in Domestic Gardens?. PLoS Neglected Tropical Diseases, 9 (3) e0003635, e0003635. doi: 10.1371/journal.pntd.0003635
2014
Journal Article
The microbiology of impetigo in Indigenous children: associations between Streptococcus pyogenes, Staphylococcus aureus, scabies, and nasal carriage
Bowen, Asha C., Tong, Steven Y. C., Chatfield, Mark D. and Carapetis, Jonathan R. (2014). The microbiology of impetigo in Indigenous children: associations between Streptococcus pyogenes, Staphylococcus aureus, scabies, and nasal carriage. BMC Infectious Diseases, 14 (1) 727. doi: 10.1186/s12879-014-0727-5
2014
Journal Article
Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial
Bowen, Asha C., Tong, Steven Y. C., Andrews, Ross M., O'Meara, Irene M., McDonald, Malcolm I., Chatfield, Mark D., Currie, Bart J. and Carapetis, Jonathan R. (2014). Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial. Lancet, 384 (9960), 2132-2140. doi: 10.1016/S0140-6736(14)60841-2
2014
Journal Article
Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer
Mahon, K. L., Qu, W., Devaney, J., Paul, C., Castillo, L., Wykes, R. J., Chatfield, M. D., Boyer, M. J., Stockler, M. R., Marx, G., Gurney, H., Mallesara, G., Molloy, P. L., Horvath, L. G. and Clark, S. J. (2014). Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer. British Journal of Cancer, 111 (9), 1802-1809. doi: 10.1038/bjc.2014.463
2014
Journal Article
Progressive increase in community-associated methicillin-resistant Staphylococcus aureus in Indigenous populations in northern Australia from 1993 to 2012
Tong, S. Y. C., Varrone, L., Chatfield, M. D., Beaman, M. and Giffard, P. M. (2014). Progressive increase in community-associated methicillin-resistant Staphylococcus aureus in Indigenous populations in northern Australia from 1993 to 2012. Epidemiology and Infection, 143 (07), 1519-1523. doi: 10.1017/s0950268814002611
2014
Journal Article
Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules
Leach, Amanda Jane, Wigger, Christine, Andrews, Ross, Chatfield, Mark, Smith-Vaughan, Heidi and Morris, Peter Stanley (2014). Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules. BMC Pediatrics, 14 (1) 200. doi: 10.1186/1471-2431-14-200
2014
Journal Article
Performance of formulas for estimating glomerular filtration rate in Indigenous Australians with and without Type 2 diabetes: the eGFR Study
Maple-Brown, L. J., Ekinci, E. I., Hughes, J. T., Chatfield, M., Lawton, P. D., Jones, G. R. D., Ellis, A. G., Sinha, A., Cass, A., Hoy, W. E., O'Dea, K., Jerums, G. and Macisaac, .R. J. (2014). Performance of formulas for estimating glomerular filtration rate in Indigenous Australians with and without Type 2 diabetes: the eGFR Study. Diabetic Medicine, 31 (7), 829-838. doi: 10.1111/dme.12426
2014
Journal Article
Clinical validity of the nerve root sedimentation sign in patients with suspected lumbar spinal stenosis
Barz, Thomas, Staub, Lukas P., Melloh, Markus, Hamann, Gregor, Lord, Sarah J., Chatfield, Mark D., Bossuyt, Patrick M., Lange, Joern and Merk, Harry R. (2014). Clinical validity of the nerve root sedimentation sign in patients with suspected lumbar spinal stenosis. Spine Journal, 14 (4), 667-674. doi: 10.1016/j.spinee.2013.06.105
2014
Conference Publication
Methylated glutathione s-transferase 1 (mGSTP1) as a potential plasma epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer (CRPC)
Mahon, Kate Lynette, Qu, Wenjia, Devaney, James, Paul, Cheryl, Castillo, Lesley, Wykes, Richard, Chatfield, Mark D., Boyer, Michael J., Stockler, Martin R., Marx, Gavin M., Gurney, Howard, Gowda, Girish Mallesara Hiriyanna, Molloy, Peter, Horvath, Lisa and Clark, Susan J. (2014). Methylated glutathione s-transferase 1 (mGSTP1) as a potential plasma epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer (CRPC). Genitourinary Cancers Symposium, San Francisco Ca, Jan 30-Feb 01, 2014. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/jco.2014.32.4_suppl.11
2014
Journal Article
FluMum: A prospective cohort study of mother-infant pairs assessing the effectiveness of maternal influenza vaccination in revention of influenza in early infancy
O'Grady, K.-A.F., McHugh, L., Nolan, T., Richmond, P., Wood, N., Marshall, H.S., Lambert, S.B., Chatfield, M. and Andrews, R.M. (2014). FluMum: A prospective cohort study of mother-infant pairs assessing the effectiveness of maternal influenza vaccination in revention of influenza in early infancy. BMJ Open, 4 (6) e005676, 1-7. doi: 10.1136/bmjopen-2014-005676
2014
Journal Article
Accelerated BEP for metastatic germ cell tumours: a multicenter phase II trial by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP)
Grimison, P. S., Stockler, M. R., Chatfield, M., Thomson, D. B., Gebski, V., Friedlander, M., Boland, A. L., Houghton, B., Gurney, H., Rosenthal, M., Singhal, N., Kichenadasse, G., Wong, S. S., Lewis, C. R., Vasey, P. A. and Toner, G. C. (2014). Accelerated BEP for metastatic germ cell tumours: a multicenter phase II trial by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP). Annals of Oncology, 25 (1), 143-148. doi: 10.1093/annonc/mdt369
2013
Journal Article
HPV status of oropharyngeal cancer by combination HPV DNA/p16 testing: biological relevance of discordant results
Hong, Angela, Jones, Deanna, Chatfield, Mark, Lee, C. Soon, Zhang, Mei, Clark, Jonathan, Elliott, Michael, Harnett, Gerald, Milross, Christopher and Rose, Barbara (2013). HPV status of oropharyngeal cancer by combination HPV DNA/p16 testing: biological relevance of discordant results. Annals of Surgical Oncology, 20 (3), S450-S458. doi: 10.1245/s10434-012-2778-4
2013
Journal Article
A Single Dose of Azithromycin Does Not Improve Clinical Outcomes of Children Hospitalised with Bronchiolitis: A Randomised, Placebo-Controlled Trial
McCallum G.B., Morris P.S., Chatfield M.D., Maclennan C., White A.V., Sloots T.P., Mackay I.M. and Chang A.B. (2013). A Single Dose of Azithromycin Does Not Improve Clinical Outcomes of Children Hospitalised with Bronchiolitis: A Randomised, Placebo-Controlled Trial. PLoS ONE, 8 (9) e74316, 1-9. doi: 10.1371/journal.pone.0074316
2013
Journal Article
Impaired pulmonary nitric oxide bioavailability in pulmonary tuberculosis: association with disease severity and delayed mycobacterial clearance with treatment
Ralph, Anna P., Yeo, Tsin W., Salome, Cheryl M., Waramori, Govert, Pontororing, Gysje J., Kenangalem, Enny, Sandjaja,, Tjitra, Emiliana, Lumb, Richard, Maguire, Graeme P., Price, Ric N., Chatfield, Mark D., Kelly, Paul M. and Anstey, Nicholas M. (2013). Impaired pulmonary nitric oxide bioavailability in pulmonary tuberculosis: association with disease severity and delayed mycobacterial clearance with treatment. Journal of Infectious Diseases, 208 (4), 616-626. doi: 10.1093/infdis/jit248
2013
Journal Article
L-arginine and Vitamin D adjunctive therapies in pulmonary tuberculosis: a randomised, double-blind, placebo-controlled trial
Ralph, Anna P., Waramori, Govert, Pontororing, Gysje J., Kenangalem, Enny, Wiguna, Andri, Tjitra, Emiliana, Sandjaja,, Lolong, Dina B., Yeo, Tsin W., Chatfield, Mark D., Soemanto, Retno K., Bastian, Ivan, Lumb, Richard, Maguire, Graeme P., Eisman, John, Price, Ric N., Morris, Peter S., Kelly, Paul M. and Anstey, Nicholas M. (2013). L-arginine and Vitamin D adjunctive therapies in pulmonary tuberculosis: a randomised, double-blind, placebo-controlled trial. Plos One, 8 (8) e70032, e70032. doi: 10.1371/journal.pone.0070032
2013
Journal Article
Stores Healthy Options Project in Remote Indigenous Communities (SHOP@RIC): a protocol of a randomised trial promoting healthy food and beverage purchases through price discounts and in-store nutrition education
Brimblecombe, Julie, Ferguson, Megan, Liberato, Selma C., Ball, Kylie, Moodie, Marjory L., Magnus, Anne, Miles, Edward, Leach, Amanda J., Chatfield, Mark D., Mhurchu, Cliona Ni, O'Dea, Kerin and Bailie, Ross S. (2013). Stores Healthy Options Project in Remote Indigenous Communities (SHOP@RIC): a protocol of a randomised trial promoting healthy food and beverage purchases through price discounts and in-store nutrition education. BMC Public Health, 13 (1) 744. doi: 10.1186/1471-2458-13-744
2013
Journal Article
Longitudinal Nasopharyngeal Carriage and Antibiotic Resistance of Respiratory Bacteria in Indigenous Australian and Alaska Native Children with Bronchiectasis
Hare, Kim M., Singleton, Rosalyn J., Grimwood, Keith, Valery, Patricia C., Cheng, Allen C., Morris, Peter S., Leach, Amanda J., Smith-Vaughan, Heidi C., Chatfield, Mark, Redding, Greg, Reasonover, Alisa L., McCallum, Gabrielle B., Chikoyak, Lori, McDonald, Malcolm I., Brown, Ngiare, Torzillo, Paul J. and Chang, Anne B. (2013). Longitudinal Nasopharyngeal Carriage and Antibiotic Resistance of Respiratory Bacteria in Indigenous Australian and Alaska Native Children with Bronchiectasis. Plos One, 8 (8) e70478, e70478.1-e70478.8. doi: 10.1371/journal.pone.0070478
2013
Journal Article
Severity scoring systems: Are they internally valid, reliable and predictive of oxygen use in children with acute bronchiolitis?
Mccallum, G.B., Morris, P.S., Wilson, C.C., Versteegh, L.A., Ward, L.M., Chatfield, M.D. and Chang, A.B. (2013). Severity scoring systems: Are they internally valid, reliable and predictive of oxygen use in children with acute bronchiolitis?. Pediatric Pulmonology, 48 (8), 797-803. doi: 10.1002/ppul.22627
Funding
Current funding
Past funding
Supervision
Availability
- Mr Mark Chatfield is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Statistical advisor (but NOT primary supervisor)
I am available to be a statistical advisor, but am not available to be a primary supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Randomised controlled trial of ceftolozane-tazobactam vs meropenem for bloodstream infections
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Doctor Philosophy
Treatment Strategies for Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-producing Enterobacterales
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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Doctor Philosophy
Novel trial design in evaluation of antibiotics.
Associate Advisor
Other advisors: Dr Patrick Harris
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Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Associate Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Associate Professor Adam Irwin
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Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
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Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
Completed supervision
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2024
Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Media
Enquiries
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