Associate Professor Victor Anggono
Associate Professor

Victor Anggono

Email: 
Phone: 
+61 7 334 66417
Phone: 
+61 7 334 66325

Background

Victor Anggono is a neurochemist/neuronal cell biologist with an established track record in studying the molecular and cellular mechanisms of synaptic plasticity, focusing on the regulation of neuronal trafficking at the pre- and post-synaptic compartments. He received his PhD from the University of Sydney in 2007. Supported by an NHMRC CJ Martin and a Human Frontiers Long-term Fellowships, he subsequently conducted postdoctoral training at the Department of Neuroscience at Johns Hopkins University (Baltimore, USA). Victor returned to Australia in 2012 and established an independent research laboratory at the Queensland Brain Institute, The University of Queensland in 2014. He is currently an Associate Professor (supported by an ARC Future Fellowship) and leads a team of 10 researchers. Victor has published more than 60 papers in leading journals, including Nature Neuroscience, Nature Communications, PNAS, Cell Reports and Journal of Neuroscience. His work has received 7 recommendations from the Faculty Opinions and attracted over 4,900 citations (Google Scholar). Victor was awarded the Boomerang Award (Australian Society for Biochemistry and Molecular Biology, 2011) and the Young Scientist Award (Federation of Asian and Oceanian Biochemists and Molecular Biologists, 2015) for his research excellence. He has an excellent track record of mentoring, with two of his first postdoctoral fellows being funded by ARC DECRAs. He has supervised 6 PhD and 6 Honours students to completion.

Availability

Associate Professor Victor Anggono is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Sydney

Research interests

  • Neuronal Trafficking

    The molecular basis of vesicles and receptors transports between sub-cellular compartments essential for neuronal communications, learning and memory.

  • Neuroepigenetics

    The molecular mechanisms underlying activity-dependent gene transcription in synaptic plasticity, a cellular correlate of learning and memory.

Research impacts

How neurons communicate with each other in the brain is one of the outstanding and most fascinating questions in modern neuroscience. This basic science research program will provide a detailed understanding of three essential biological processes; (i) presynaptic vesicle recycling, (ii) postsynaptic glutamate receptor trafficking, and (iii) epigenetic regulation of synaptic plasticity. These systems are crucial for virtually all function in the central nervous system. As most of these processes have been implicated in neurological disorders, such as epilepsy, Alzheimer's disease, schizophrenia and bipolar disorder, results from Dr Anggono's research program will also provide insights into the principles underpinning disease aetiology. Understanding of the molecular mechanisms of neuronal communications will allow us to devise potential meaningful and novel therapeutic strategies to target these neurological disorders.

Search Professor Victor Anggono’s works on UQ eSpace

77 works between 2006 and 2025
All (77) Journal Article (65) Conference Publication (7) Book Chapter (5)

21 - 40 of 77 works

2023

Journal Article

Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice

Leiter, Odette, Brici, David, Fletcher, Stephen J., Yong, Xuan Ling Hilary, Widagdo, Jocelyn, Matigian, Nicholas, Schroer, Adam B., Bieri, Gregor, Blackmore, Daniel G., Bartlett, Perry F., Anggono, Victor, Villeda, Saul A. and Walker, Tara L. (2023). Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice. Nature Communications, 14 (1) 4375, 1-20. doi: 10.1038/s41467-023-39873-9

Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice

2023

Journal Article

Ubiquitination of the GluA1 subunit of AMPA receptors is required for synaptic plasticity, memory and cognitive flexibility

Guntupalli, Sumasri, Park, Pojeong, Han, Dae Hee, Zhang, Lingrui, Yong, Xuan Ling Hilary, Ringuet, Mitchell, Blackmore, Daniel G., Jhaveri, Dhanisha J., Koentgen, Frank, Widagdo, Jocelyn, Kaang, Bong-Kiun and Anggono, Victor (2023). Ubiquitination of the GluA1 subunit of AMPA receptors is required for synaptic plasticity, memory and cognitive flexibility. The Journal of Neuroscience, 43 (30), 5448-5457. doi: 10.1523/jneurosci.1542-22.2023

Ubiquitination of the GluA1 subunit of AMPA receptors is required for synaptic plasticity, memory and cognitive flexibility

2023

Journal Article

Identification of phosphorylated Tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission

Radford, Rowan A. W., Rayner, Stephanie L., Szwaja, Paulina, Morsch, Marco, Cheng, Flora, Zhu, Tianyi, Widagdo, Jocelyn, Anggono, Victor, Pountney, Dean L., Chung, Roger and Lee, Albert (2023). Identification of phosphorylated Tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission. Journal of Neurochemistry, 165 (4), 563-586. doi: 10.1111/jnc.15796

Identification of phosphorylated Tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission

2023

Journal Article

The N 6 ‐methyladenosine RNA landscape in the aged mouse hippocampus

Huang, He, Song, Renhua, Wong, Justin J.‐L., Anggono, Victor and Widagdo, Jocelyn (2023). The N 6 ‐methyladenosine RNA landscape in the aged mouse hippocampus. Aging Cell, 22 (1) e13755, 1-8. doi: 10.1111/acel.13755

The N 6 ‐methyladenosine RNA landscape in the aged mouse hippocampus

2022

Journal Article

Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons

Widagdo, Jocelyn, Udagedara, Saumya, Bhembre, Nishita, Tan, Jing Zhi Anson, Neureiter, Lara, Huang, Jie, Anggono, Victor and Lee, Mihwa (2022). Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons. Open Biology, 12 (9) 220187, 1-12. doi: 10.1098/rsob.220187

Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons

2022

Journal Article

The m6A-epitranscriptome in brain plasticity, learning and memory

Widagdo, Jocelyn, Wong, Justin J.-L. and Anggono, Victor (2022). The m6A-epitranscriptome in brain plasticity, learning and memory. Seminars in Cell and Developmental Biology, 125, 110-121. doi: 10.1016/j.semcdb.2021.05.023

The m6A-epitranscriptome in brain plasticity, learning and memory

2022

Journal Article

Editorial – The Making of Memories

Anggono, Victor and Opazo, Patricio (2022). Editorial – The Making of Memories. Seminars in Cell and Developmental Biology, 125, 66-67. doi: 10.1016/j.semcdb.2022.02.001

Editorial – The Making of Memories

2022

Journal Article

Phototransduction in a marine sponge provides insights into the origin of animal vision

Wong, Eunice, Anggono, Victor, Williams, Stephen R., Degnan, Sandie M. and Degnan, Bernard M. (2022). Phototransduction in a marine sponge provides insights into the origin of animal vision. iScience, 25 (6) 104436, 104436. doi: 10.1016/j.isci.2022.104436

Phototransduction in a marine sponge provides insights into the origin of animal vision

2022

Journal Article

The multifaceted effects of YTHDC1-mediated nuclear m6A recognition

Widagdo, Jocelyn, Anggono, Victor and Wong, Justin J.-L. (2022). The multifaceted effects of YTHDC1-mediated nuclear m6A recognition. Trends in Genetics, 38 (4), 325-332. doi: 10.1016/j.tig.2021.11.005

The multifaceted effects of YTHDC1-mediated nuclear m6A recognition

2022

Journal Article

The metalloprotease ADM-4/ADAM17 promotes axonal repair

Ho, Xue Yan, Coakley, Sean, Amor, Rumelo, Anggono, Victor and Hilliard, Massimo A. (2022). The metalloprotease ADM-4/ADAM17 promotes axonal repair. Science Advances, 8 (11) eabm2882, eabm2882. doi: 10.1126/sciadv.abm2882

The metalloprotease ADM-4/ADAM17 promotes axonal repair

2020

Journal Article

An epilepsy-associated GRIN2A rare variant disrupts CaMKIIα phosphorylation of GluN2A and NMDA receptor trafficking

Mota Vieira, Marta, Nguyen, Thien A., Wu, Kunwei, Badger, John D., Collins, Brett M., Anggono, Victor, Lu, Wei and Roche, Katherine W. (2020). An epilepsy-associated GRIN2A rare variant disrupts CaMKIIα phosphorylation of GluN2A and NMDA receptor trafficking. Cell Reports, 32 (9) 108104, 108104. doi: 10.1016/j.celrep.2020.108104

An epilepsy-associated GRIN2A rare variant disrupts CaMKIIα phosphorylation of GluN2A and NMDA receptor trafficking

2020

Journal Article

Altered expression of the m6A methyltransferase METTL3 in Alzheimer’s disease

Huang (黄 河), He, Camats-Perna, Judith, Medeiros, Rodrigo, Anggono, Victor and Widagdo, Jocelyn (2020). Altered expression of the m6A methyltransferase METTL3 in Alzheimer’s disease. eNeuro, 7 (5) ENEURO.0125-20.2020, ENEURO.0125-20.2020. doi: 10.1523/eneuro.0125-20.2020

Altered expression of the m6A methyltransferase METTL3 in Alzheimer’s disease

2020

Journal Article

Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ

Huang, Jie, Ringuet, Mitchell, Whitten, Andrew E, Caria, Sofia, Lim, Yee Wa, Badhan, Rahul, Anggono, Victor and Lee, Mihwa (2020). Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ. Nucleic Acids Research, 48 (6), 3356-3365. doi: 10.1093/nar/gkaa076

Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ

2020

Journal Article

Subunit-specific augmentation of AMPA receptor ubiquitination by phorbol ester

Widagdo, Jocelyn, Kerk, Jun Wei, Guntupalli, Sumasri, Huganir, Richard L. and Anggono, Victor (2020). Subunit-specific augmentation of AMPA receptor ubiquitination by phorbol ester. Cellular and Molecular Neurobiology, 40 (7), 1213-1222. doi: 10.1007/s10571-020-00809-2

Subunit-specific augmentation of AMPA receptor ubiquitination by phorbol ester

2020

Journal Article

Regulation of NMDA glutamate receptor functions by the GluN2 subunits

Vieira, Marta, Yong, Xuan Ling Hilary, Roche, Katherine W. and Anggono, Victor (2020). Regulation of NMDA glutamate receptor functions by the GluN2 subunits. Journal of Neurochemistry, 154 (2) jnc.14970, 121-143. doi: 10.1111/jnc.14970

Regulation of NMDA glutamate receptor functions by the GluN2 subunits

2020

Journal Article

The interaction between contactin and amyloid precursor protein and its role in Alzheimer’s disease

Bamford, Rosemary A., Widagdo, Jocelyn, Takamura, Natsuki, Eve, Madeline, Anggono, Victor and Oguro-Ando, Asami (2020). The interaction between contactin and amyloid precursor protein and its role in Alzheimer’s disease. Neuroscience, 424, 184-202. doi: 10.1016/j.neuroscience.2019.10.006

The interaction between contactin and amyloid precursor protein and its role in Alzheimer’s disease

2019

Journal Article

Co-expression of synaptic genes in the sponge Amphimedon queenslandica uncovers ancient neural submodules

Wong, Eunice, Mölter, Jan, Anggono, Victor, Degnan, Sandie M. and Degnan, Bernard M. (2019). Co-expression of synaptic genes in the sponge Amphimedon queenslandica uncovers ancient neural submodules. Scientific Reports, 9 (1) 15781, 15781. doi: 10.1038/s41598-019-51282-x

Co-expression of synaptic genes in the sponge Amphimedon queenslandica uncovers ancient neural submodules

2019

Journal Article

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

Gooch, Helen, Cui, Xiaoying, Anggono, Victor, Trzaskowski, Maciej, Tan, Men Chee, Eyles, Darryl W., Burne, Thomas H. J., Jang, Se Eun, Mattheisen, Manuel, Hougaard, David M., Pedersen, Bent Nørgaard, Cohen, Arieh, Mortensen, Preben B., Sah, Pankaj and McGrath, John J. (2019). 1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex. Translational Psychiatry, 9 (1) 281, 281. doi: 10.1038/s41398-019-0626-z

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

2019

Journal Article

Syntaxin1A neomorphic mutations promote rapid recovery from isoflurane anesthesia in Drosophila melanogaster

Troup, Michael, Zalucki, Oressia H., Kottler, Benjamin D., Karunanithi, Shanker, Anggono, Victor and van Swinderen, Bruno (2019). Syntaxin1A neomorphic mutations promote rapid recovery from isoflurane anesthesia in Drosophila melanogaster. Anesthesiology, 131 (3), 555-568. doi: 10.1097/ALN.0000000000002850

Syntaxin1A neomorphic mutations promote rapid recovery from isoflurane anesthesia in Drosophila melanogaster

2019

Journal Article

NFIX-mediated inhibition of neuroblast branching regulates migration within the adult mouse ventricular–subventricular zone

Zalucki, Oressia, Harris, Lachlan, Harvey, Tracey J., Harkins, Danyon, Widagdo, Jocelyn, Oishi, Sabrina, Matuzelski, Elise, Yong, Xuan Ling Hilary, Schmidt, Hannes, Anggono, Victor, Burne, Thomas H. J., Gronostajski, Richard M. and Piper, Michael (2019). NFIX-mediated inhibition of neuroblast branching regulates migration within the adult mouse ventricular–subventricular zone. Cerebral Cortex, 29 (8), 3590-3604. doi: 10.1093/cercor/bhy233

NFIX-mediated inhibition of neuroblast branching regulates migration within the adult mouse ventricular–subventricular zone

Current funding

  • 2026 - 2029
    Long-range calcium-dependent neuronal signalling in learning and memory
    ARC Discovery Projects
    Open grant
  • 2025 - 2026
    Molecular mechanisms of neuronal plasticity
    Research Donation Generic
    Open grant
  • 2024 - 2027
    Unraveling the physiological and disease-enabling functions of Tau protein
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2026
    Molecular basis of glutamate receptor trafficking in neuronal plasticity
    ARC Future Fellowships
    Open grant
  • 2022 - 2025
    Regulation of activity-induced glutamate receptor trafficking in neurons
    ARC Discovery Projects
    Open grant

Past funding

  • 2024 - 2025
    Characterisation of a de novo WDR26 rare genetic variant associated with neurodevelopmental disorders
    Australian Functional Genomics Network
    Open grant
  • 2021 - 2022
    Molecular mechanisms underlying the cytoplasmic aggregation of the RNA binding protein, SFPQ, in ALS
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2019 - 2022
    Regulation of glutamate receptor dynamics in mammalian central neurons
    ARC Discovery Projects
    Open grant
  • 2018 - 2021
    Regulation of glutamate receptor trafficking by the calcium- and lipid-binding protein, copine-6
    NHMRC Project Grant
    Open grant
  • 2017
    Australia-China Young Scientists Exchange Program 2017
    Australian Academy of Technological Sciences and Engineering
    Open grant
  • 2017 - 2019
    Regulation of synaptic vesicle endocytosis by membrane-sensing proteins
    ARC Discovery Projects
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016
    Travel Award for the 39th Annual Meeting of the Japan Neuroscience Society
    Japan Neuroscience Society
    Open grant
  • 2016 - 2018
    Molecular mechanisms underlying recovery from general anaesthesia
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Sorting out the synapse: the role of intracellular trafficking in NMDA receptor homeostasis
    NHMRC Project Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Ubiquitinomic profiling of synaptic proteins in Alzheimer's Disease
    Alzheimer's Australia Dementia Research Foundation
    Open grant
  • 2015 - 2018
    Targeting the synaptic actin cytoskeleton in Alzheimer's Disease (NHMRC Project Grant administered by UNSW)
    University of New South Wales
    Open grant
  • 2014
    Transcriptional Profiling of Long Non-coding RNAs in Synaptic Plasticity
    UQ Early Career Researcher
    Open grant
  • 2012 - 2013
    The role of synaptotagmin-1 ubiquitination in synaptic transmission
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2012 - 2014
    NHMRC Training Fellowship (CJ Martin): The role of stargazin and TARP phosphorylation in synaptic plasticity
    NHMRC Training (Postdoctoral) Fellowship
    Open grant

Availability

Associate Professor Victor Anggono is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Regulation of synapse to nucleus signalling during synaptic plasticity

    Principal Advisor

    Other advisors: Dr Jocelyn Widagdo, Dr Anson Tan

  • Doctor Philosophy

    APP interacting protein as a key target of neuronal activity regulator in healthy aging

    Principal Advisor

  • Doctor Philosophy

    Identification and characterisation of novel CaMKII¿ substrates in synaptic plasticity

    Principal Advisor

    Other advisors: Professor Brett Collins

  • Doctor Philosophy

    Neural mechanism of axonal swelling formation during aging

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    Epigenetic Regulation of Learning and Memory

    Associate Advisor

    Other advisors: Dr Anson Tan, Dr Jocelyn Widagdo

  • Doctor Philosophy

    Epitranscriptomic regulation of memory formation

    Associate Advisor

    Other advisors: Dr Jocelyn Widagdo

  • Doctor Philosophy

    Understanding the mechanisms by which exercise and diet mediate brain plasticity and cognition in ageing

    Associate Advisor

    Other advisors: Dr Tara Walker

  • Doctor Philosophy

    The effects of lifestyle interventions in adult neurogenesis and cognition

    Associate Advisor

    Other advisors: Dr Tara Walker

Completed supervision

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