Associate Professor Victor Anggono
Associate Professor

Victor Anggono

Email: 
Phone: 
+61 7 334 66417
Phone: 
+61 7 334 66325

Background

Victor Anggono received his PhD in 2007 from the University of Sydney and undertook his postdoctoral training at the Johns Hopkins University in Baltimore, USA. In 2012, Dr Anggono returned to Australia as an NHMRC CJ Martin Research Fellow and joined the Queensland Brain Institute at the University of Queensland, where he is currently a Senior Research Fellow and Group Leader at the Clem Jones Centre for Ageing Dementia Research. His research aims to understand the molecular mechanisms of synaptic vesicle and glutamate receptor trafficking in neurons, processes that are essential for synaptic transmission, plasticity, learning and memory, and how their dysregulations impact on the pathophysiology of neurodegenerative diseases and neuropsychiatric disorders. Dr Anggono has published in journals such as Nature Neuroscience, Neuron, The Proceedings of the National Academy of Sciences USA, Journal of Neuroscience and Cell Reports, and has attracted more than 1500 citations. For his works, Dr Anggono was awarded the Boomerang Award (Australian Society for Biochemistry and Molecular Biology, 2011), the Young Scientist Award (Federation of Asian and Oceanian Biochemists and Molecular Biologists, 2015), the Science to Art Award (NHMRC, 2015) and more recently the Young Investigator Award (Asian-Pacific Society for Neurochemistry, 2016).

Availability

Associate Professor Victor Anggono is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Sydney

Research interests

  • Neuronal Trafficking

    The molecular basis of vesicles and receptors transports between sub-cellular compartments essential for neuronal communications, learning and memory.

  • Neuroepigenetics

    The molecular mechanisms underlying activity-dependent gene transcription in synaptic plasticity, a cellular correlate of learning and memory.

Research impacts

How neurons communicate with each other in the brain is one of the outstanding and most fascinating questions in modern neuroscience. This basic science research program will provide a detailed understanding of three essential biological processes; (i) presynaptic vesicle recycling, (ii) postsynaptic glutamate receptor trafficking, and (iii) epigenetic regulation of synaptic plasticity. These systems are crucial for virtually all function in the central nervous system. As most of these processes have been implicated in neurological disorders, such as epilepsy, Alzheimer's disease, schizophrenia and bipolar disorder, results from Dr Anggono's research program will also provide insights into the principles underpinning disease aetiology. Understanding of the molecular mechanisms of neuronal communications will allow us to devise potential meaningful and novel therapeutic strategies to target these neurological disorders.

Search Professor Victor Anggono’s works on UQ eSpace

74 works between 2006 and 2025
All (74) Journal Article (64) Book Chapter (5) Conference Publication (5)

61 - 74 of 74 works

2011

Journal Article

Phosphorylation of dynamin II at serine-764 is associated with cytokinesis

Chircop, Megan, Sarcevic, Boris, Larsen, Martin R., Malladi, Chandra S., Chau, Ngoc, Zavortink, Michael, Smith, Charlotte M., Quan, Annie, Anggono, Victor, Hains, Peter G., Graham, Mark E. and Robinson, Phillip J. (2011). Phosphorylation of dynamin II at serine-764 is associated with cytokinesis. Biochimica Et Biophysica Acta-Molecular Cell Research, 1813 (10), 1689-1699. doi: 10.1016/j.bbamcr.2010.12.018

Phosphorylation of dynamin II at serine-764 is associated with cytokinesis

2011

Journal Article

Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism

Mejias, Rebeca, Adamczyk, Abby, Anggono, Victor, Niranjan, Tejasvi, Thomas, Gareth M., Sharma, Kamal, Skinner, Cindy, Schwartz, Charles E., Stevenson, Roger E., Fallin, M. Daniele, Kaufmann, Walter, Pletnikov, Mikhail, Valle, David, Huganir, Richard L. and Wang, Tao (2011). Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism. Proceedings of the National Academy of Sciences of the United States of America, 108 (12), 4920-4925. doi: 10.1073/pnas.1102233108

Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism

2011

Journal Article

PICK1 Loss of Function Occludes Homeostatic Synaptic Scaling

Anggono, Victor, Clem, Roger L. and Huganir, Richard L. (2011). PICK1 Loss of Function Occludes Homeostatic Synaptic Scaling. Journal of Neuroscience, 31 (6), 2188-2196. doi: 10.1523/JNEUROSCI.5633-10.2011

PICK1 Loss of Function Occludes Homeostatic Synaptic Scaling

2010

Book Chapter

Dynamin

Anggono, V. and Robinson, P. J. (2010). Dynamin. Encyclopedia of Neuroscience. (pp. 725-735) Elsevier Ltd. doi: 10.1016/B978-008045046-9.01363-2

Dynamin

2010

Journal Article

PICK1 Regulates Incorporation of Calcium-Permeable AMPA Receptors during Cortical Synaptic Strengthening

Clem, Roger L., Anggono, Victor and Huganir, Richard L. (2010). PICK1 Regulates Incorporation of Calcium-Permeable AMPA Receptors during Cortical Synaptic Strengthening. Journal of Neuroscience, 30 (18), 6360-6366. doi: 10.1523/JNEUROSCI.6276-09.2010

PICK1 Regulates Incorporation of Calcium-Permeable AMPA Receptors during Cortical Synaptic Strengthening

2010

Journal Article

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

Thorsen, Thor S., Madsen, Kenneth L., Rebola, Nelson, Rathje, Mette, Anggono, Victor, Bach, Anders, Moreira, Irina S., Stuhr-Hansen, Nicolai, Dyhring, Tino, Peters, Dan, Beuming, Thijs, Huganir, Richard, Weinstein, Harel, Mulle, Christophe, Stromgaard, Kristian, Ronn, Lars Christian B. and Gether, Ulrik (2010). Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. Proceedings of the National Academy of Sciences of the United States of America, 107 (1), 413-418. doi: 10.1073/pnas.0902225107

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

2009

Journal Article

The Phospho-Dependent Dynamin-Syndapin Interaction Triggers Activity-Dependent Bulk Endocytosis of Synaptic Vesicles

Clayton, Emma L., Anggono, Victor, Smillie, Karen J., Chau, Ngoc, Robinson, Phillip J. and Cousin, Michael A. (2009). The Phospho-Dependent Dynamin-Syndapin Interaction Triggers Activity-Dependent Bulk Endocytosis of Synaptic Vesicles. Journal of Neuroscience, 29 (24), 7706-7717. doi: 10.1523/JNEUROSCI.1976-09.2009

The Phospho-Dependent Dynamin-Syndapin Interaction Triggers Activity-Dependent Bulk Endocytosis of Synaptic Vesicles

2009

Book Chapter

Dynamin

Anggono, V. and Robinson, P. J. (2009). Dynamin. Encyclopedia of Neuroscience. (pp. 725-735) edited by Larry R. Squire. Amsterdam , The Netherlands: Elseiver.

Dynamin

2009

Book Chapter

Dynamin

Anggono, V. and Robinson, P. J. (2009). Dynamin. Encyclopedia of Neuroscience: Volumes 1-11. (pp. V3-725-V3-735) Elsevier. doi: 10.1016/B978-008045046-9.01363-2

Dynamin

2008

Book Chapter

Styryl dye-based synaptic vesicle recycling assay in cultured cerebellar granule neurons

Anggono, Victor, Cousin, Michael A. and Robinson, Phillip J. (2008). Styryl dye-based synaptic vesicle recycling assay in cultured cerebellar granule neurons. Membrane Trafficking. (pp. 333-345) edited by Ales Vancura. Totowa, NJ. United States: Humana Press. doi: 10.1007/978-1-59745-261-8_25

Styryl dye-based synaptic vesicle recycling assay in cultured cerebellar granule neurons

2008

Book Chapter

Septins and the synapse

Xue, J., Anggono, V. and Robinson, P. J. (2008). Septins and the synapse. The Septins. (pp. 247-267) edited by Peter A. Hall, S. E. Hilary Russell and John R. Pringle. Chichester, U.K.: John Wiley & Sons. doi: 10.1002/9780470779705.ch11

Septins and the synapse

2007

Journal Article

Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis

Anggono, Victor and Robinson, Phillip J. (2007). Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis. Journal of Neurochemistry, 102 (3), 931-943. doi: 10.1111/j.1471-4159.2007.04574.x

Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis

2007

Journal Article

The in vivo phosphorylation sites of rat brain dynamin I

Graham, Mark E., Anggono, Victor, Bache, Nicolai, Larsen, Martin R., Craft, George E. and Robinson, Phillip J. (2007). The in vivo phosphorylation sites of rat brain dynamin I. Journal of Biological Chemistry, 282 (20), 14695-14707. doi: 10.1074/jbc.M609713200

The in vivo phosphorylation sites of rat brain dynamin I

2006

Journal Article

Control of synaptic vesicle endocytosis by dephosphorylation of dynamin I

Robinson, P. J., Anggono, V. and Cousin, M. A. (2006). Control of synaptic vesicle endocytosis by dephosphorylation of dynamin I. Neurosignals, 15 (1), 49-49.

Control of synaptic vesicle endocytosis by dephosphorylation of dynamin I

Current funding

  • 2024 - 2025
    Characterisation of a de novo WDR26 rare genetic variant associated with neurodevelopmental disorders
    Australian Functional Genomics Network
    Open grant
  • 2024 - 2027
    Unraveling the physiological and disease-enabling functions of Tau protein
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2026
    Molecular basis of glutamate receptor trafficking in neuronal plasticity
    ARC Future Fellowships
    Open grant
  • 2022 - 2025
    Regulation of activity-induced glutamate receptor trafficking in neurons
    ARC Discovery Projects
    Open grant

Past funding

  • 2021 - 2022
    Molecular mechanisms underlying the cytoplasmic aggregation of the RNA binding protein, SFPQ, in ALS
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2019 - 2022
    Regulation of glutamate receptor dynamics in mammalian central neurons
    ARC Discovery Projects
    Open grant
  • 2018 - 2021
    Regulation of glutamate receptor trafficking by the calcium- and lipid-binding protein, copine-6
    NHMRC Project Grant
    Open grant
  • 2017
    Australia-China Young Scientists Exchange Program 2017
    Australian Academy of Technological Sciences and Engineering
    Open grant
  • 2017 - 2019
    Regulation of synaptic vesicle endocytosis by membrane-sensing proteins
    ARC Discovery Projects
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016
    Travel Award for the 39th Annual Meeting of the Japan Neuroscience Society
    Japan Neuroscience Society
    Open grant
  • 2016 - 2018
    Molecular mechanisms underlying recovery from general anaesthesia
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Sorting out the synapse: the role of intracellular trafficking in NMDA receptor homeostasis
    NHMRC Project Grant
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Ubiquitinomic profiling of synaptic proteins in Alzheimer's Disease
    Alzheimer's Australia Dementia Research Foundation
    Open grant
  • 2015 - 2018
    Targeting the synaptic actin cytoskeleton in Alzheimer's Disease (NHMRC Project Grant administered by UNSW)
    University of New South Wales
    Open grant
  • 2014
    Transcriptional Profiling of Long Non-coding RNAs in Synaptic Plasticity
    UQ Early Career Researcher
    Open grant
  • 2012 - 2013
    The role of synaptotagmin-1 ubiquitination in synaptic transmission
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2012 - 2014
    NHMRC Training Fellowship (CJ Martin): The role of stargazin and TARP phosphorylation in synaptic plasticity
    NHMRC Training (Postdoctoral) Fellowship
    Open grant

Availability

Associate Professor Victor Anggono is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    APP interacting protein as a key target of neuronal activity regulator in healthy aging

    Principal Advisor

  • Doctor Philosophy

    Regulation of sorting nexin 27 by protein phosphorylation

    Principal Advisor

    Other advisors: Professor Brett Collins

  • Doctor Philosophy

    APP interacting protein as a key target of neuronal activity regulator in healthy aging

    Principal Advisor

  • Doctor Philosophy

    Regulation of synapse to nucleus signalling during synaptic plasticity

    Principal Advisor

    Other advisors: Dr Jocelyn Widagdo, Dr Anson Tan

  • Doctor Philosophy

    Understanding the mechanisms by which exercise and diet mediate brain plasticity and cognition in ageing

    Associate Advisor

    Other advisors: Dr Tara Walker

  • Doctor Philosophy

    The Neural Network Function during Aging and Death in Caenorhabditis elegans

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    Neural network function during ageing and death in Caenorhabditis elegans

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    Neural mechanism of axonal swelling formation during aging

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    Neural network function during ageing and death in Caenorhabditis elegans

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    Neural network function during ageing and death in Caenorhabditis elegans

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    Use of transcriptomic, epitranscriptomic, and genomic approaches to understand neuronal homeostatic plasticity and disease

    Associate Advisor

    Other advisors: Dr Jocelyn Widagdo

  • Doctor Philosophy

    Use of transcriptomic, epitranscriptomic and genomic approaches to understand neuronal homeostatic plasticity and disease

    Associate Advisor

    Other advisors: Dr Jocelyn Widagdo

  • Doctor Philosophy

    Epigenetic Regulation of Learning and Memory

    Associate Advisor

    Other advisors: Dr Anson Tan, Dr Jocelyn Widagdo

  • Doctor Philosophy

    Neural network function during ageing and death in Caenorhabditis elegans

    Associate Advisor

    Other advisors: Dr Zhaoyu Li

  • Doctor Philosophy

    The effects of lifestyle interventions in adult neurogenesis and cognition

    Associate Advisor

    Other advisors: Dr Tara Walker

Completed supervision

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