Long-range calcium-dependent neuronal signalling in learning and memory (2026-2029)
Abstract
Memory is a core element in our brain that underpins learning, problem-solving, behaviour and environmental adaptation, and requires a continuance of gene expression and protein synthesis in nerve cells. This project aims to investigate the molecular mechanisms of how nerve cells regulate the long-term expression of memory-related genes using an innovative combination of quantitative microscopy, gene knockout mice, epigenomics and behavioural neuroscience techniques. The expected outcomes will enhance our insights into the inner workings of genes that govern learning and memory formation, knowledge that is critical for our understanding of how memory is established and maintained over the long term.
