Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

298 works between 1996 and 2025
All (298) Journal Article (262) Book Chapter (2) Conference Publication (33) Other Outputs (1)

1 - 20 of 298 works

2025

Journal Article

Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease

Boiko, Julie R, Ensbey, Kathleen S., Waltner, Olivia G, Jenkins, Isaac C, Bhise, Shruti S, MacDonald, Kelli PA, Blazar, Bruce R, Hall, Anne Marcie, Gooley, Ted A, Minnie, Simone A, Lee, Stephanie J., Furlan, Scott N and Hill, Geoffrey R (2025). Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease. Blood Journal. doi: 10.1182/blood.2024025337

Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease

2025

Journal Article

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD

Zaiken, Michael C., Jin, Sujeong, McDonald-Hyman, Cameron, Hartigan, Christina, Sage, Peter, Hippen, Keli L., Koehn, Brent H, Panoskaltsis-Mortari, Angela, Riddle, Megan J, Eide, Cindy, Tolar, Jakub, Hill, Geoffrey R, Luznik, Leo, Cutler, Corey S., Ritz, Jerome, Kean, Leslie S, Tsagaratou, Ageliki, Rao, Anjana and Blazar, Bruce R (2025). Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD. Blood Journal. doi: 10.1182/blood.2024025036

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD

2025

Journal Article

Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect

Reddi, Swetha, Senyshyn, Liliia, Ebadi, Maryam, Podlesny, Daniel, Minot, Samuel S., Gooley, Ted, Kabage, Amanda J., Hill, Geoffrey R., Lee, Stephanie J., Khoruts, Alexander and Rashidi, Armin (2025). Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect. Nature Communications, 16 (1) 1034, 1. doi: 10.1038/s41467-025-56375-y

Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect

2024

Journal Article

Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ Transplantation

Boiko, Julie R. and Hill, Geoffrey R. (2024). Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ Transplantation. Transplantation, 1-12. doi: 10.1097/tp.0000000000005298

Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ Transplantation

2024

Journal Article

The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy Outcomes

Adams, Rachael C, MacDonald, Kelli PA and Hill, Geoffrey R (2024). The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy Outcomes. Blood Journal, 145 (10), 1010-1021. doi: 10.1182/blood.2024025680

The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy Outcomes

2024

Conference Publication

Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I Trial

Krakow, Elizabeth, Connelly-Smith, Laura, Lee, Catherine J., Dunbar, Dow, Barton, Jeremy, McQueen, Beatrice P., Hill, Geoffrey R. and Appelbaum, Jacob S. (2024). Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I Trial. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-204129

Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I Trial

2024

Conference Publication

Cytokines associated with organ manifestations in chronic graft-versus-host disease

Lee, Stephanie J., Ma, Ningxin, Randolph, Timothy, Kitko, Carrie L., Cutler, Corey S., El Jurdi, Najla, Chen, George, Hamilton, Betty K., Pidala, Joseph A., Carpenter, Paul A., Arai, Sally, Onstad, Lynn, Paczesny, Sophie, Sekiguchi, Tomoko, Koyama, Motoko and Hill, Geoffrey R. (2024). Cytokines associated with organ manifestations in chronic graft-versus-host disease. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-203743

Cytokines associated with organ manifestations in chronic graft-versus-host disease

2024

Conference Publication

Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized Trial

Rashidi, Armin, Reddi, Swetha, Ebadi, Maryam, Senyshyn, Liliia, Kabage, Amanda, Minot, Samuel, Gooley, Ted, Lee, Stephanie J., Hill, Geoffrey R. and Khoruts, Alexander (2024). Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized Trial. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-202112

Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized Trial

2024

Conference Publication

Trial in Progress: ST-067 (decoy-resistant IL-18) with Teclistamab in Multiple Myeloma

Banerjee, Rahul, Vandermeer, Jacquelin, Barton, Jeremy, Mangone, Michael, McQueen, Beatrice P., Gauthier, Jordan, Ring, Aaron M, Gopal, Ajay K., Hill, Geoffrey R. and Cowan, Andrew J. (2024). Trial in Progress: ST-067 (decoy-resistant IL-18) with Teclistamab in Multiple Myeloma. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-198751

Trial in Progress: ST-067 (decoy-resistant IL-18) with Teclistamab in Multiple Myeloma

2024

Conference Publication

Donor XCR1+ and CD11b+ Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal Tract

Koyama, Motoko, Takahashi, Shuichiro, Inoue, Takayuki, Ensbey, Kathleen S., Legg, Samuel R. W., Sekiguchi, Tomoko, Nelson, Ethan, Nemychenkov, Nicole S., Joshi, Tanvi, Minnie, Simone A., Yeh, Albert C., Boiko, Julie R., Zhang, Ping, Headley, Mark B., Paik, Jisun, Amory, John K. and Hill, Geoffrey R. (2024). Donor XCR1+ and CD11b+ Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal Tract. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-209473

Donor XCR1+ and CD11b+ Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal Tract

2024

Journal Article

Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Reply

Zhang, Ping, Minnie, Simone A. and Hill, Geoffrey R. (2024). Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Reply. Journal of Clinical Investigation, 134 (20), 20. doi: 10.1172/jci184869

Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Reply

2024

Journal Article

Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy

Coffey, David G, Atilla, Pinar Ataca, Atilla, Erden, Landgren, Ola, Cowan, Andrew J, Simon, Sylvain, Pont, Margot, Comstock, Melissa L., Hill, Geoffrey R, Riddell, Stanley R. and Green, Damian J (2024). Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy. Blood Journal, 145 (2), 220-233. doi: 10.1182/blood.2024025231

Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy

2024

Conference Publication

Autocrine IL6 Signaling in Stromal Cells in Multiple Myeloma Influences the Bone Marrow Microenvironment

Matulis, Shannon, Barwick, Benjamin G., Bombin, Sergei, Ackley, James, Gupta, Vikas, Hill, Geoffrey, Green, Damian, Riddell, Stanley, Lonial, Sagar, Dhodapkar, Madhav V. and Boise, Lawrence (2024). Autocrine IL6 Signaling in Stromal Cells in Multiple Myeloma Influences the Bone Marrow Microenvironment. International Myeloma Society 21st Annual Meeting and Exposition, Rio de Janeiro, Brazil, 25-28 September 2024. New York, NY United States: Elsevier. doi: 10.1016/s2152-2650(24)02137-2

Autocrine IL6 Signaling in Stromal Cells in Multiple Myeloma Influences the Bone Marrow Microenvironment

2024

Journal Article

CMV reactivation during pre-transplantation evaluation: a novel risk factor for post-transplantation CMV reactivation

Zamora, Danniel, Xie, Hu, Sadowska-Klasa, Alicja, Kampouri, Eleftheria, Biernacki, Melinda A, Ueda Oshima, Masumi, Duke, Elizabeth R, Green, Margaret L., Kimball, Louise, Holmberg, Leona A, Waghmare, Alpana, Greninger, Alexander L, Jerome, Keith R, Hill, Geoffrey R, Hill, Joshua A, Leisenring, Wendy M and Boeckh, Michael J (2024). CMV reactivation during pre-transplantation evaluation: a novel risk factor for post-transplantation CMV reactivation. Blood Advances, 8 (17), 4568-4580. doi: 10.1182/bloodadvances.2023012234

CMV reactivation during pre-transplantation evaluation: a novel risk factor for post-transplantation CMV reactivation

2024

Journal Article

Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

Yeh, Albert C., Koyama, Motoko, Waltner, Olivia G., Minnie, Simone A., Boiko, Julie R., Shabaneh, Tamer B., Takahashi, Shuichiro, Zhang, Ping, Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Nelson, Ethan, Bhise, Shruti S., Stevens, Andrew R., Goodpaster, Tracy, Chakka, Saranya, Furlan, Scott N., Markey, Kate A., Bleakley, Marie E., Elson, Charles O., Bradley, Philip H. and Hill, Geoffrey R. (2024). Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation. Immunity, 57 (7), 1648-1664.e9. doi: 10.1016/j.immuni.2024.05.018

Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

2024

Journal Article

Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells

Ekwe, Adaeze Precious, Au, Raymond, Zhang, Ping, McEnroe, Benjamin, Tan, Mei Ling, Saldan, Alda, Henden, Andrea S., Hutchins, Cheryl, Henderson, Ashleigh, Mudie, Kari, Kerr, Keri, Fuery, Madonna, Kennedy, Glen A., Hill, Geoffrey R. and Tey, Siok-Keen (2024). Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells. Cytotherapy, 26 (7), 719-728. doi: 10.1016/j.jcyt.2024.02.023

Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells

2024

Journal Article

Autophagy prevents graft failure during murine Graft versus Host Disease

Lineburg, Katie E., Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W., Hill, Geoffrey R., Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972

Autophagy prevents graft failure during murine Graft versus Host Disease

2024

Journal Article

TIM-3<SUP>+</SUP> CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies

Minnie, Simone A., Waltner, Olivia G., Zhang, Ping, Takahashi, Shuichiro, Nemychenkov, Nicole S., Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R. W., Comstock, Melissa, Boiko, Julie R., Nelson, Ethan, Bhise, Shruti S., Wilkens, Alec B., Koyama, Motoko, Dhodapkar, Madhav V., Chesi, Marta, Riddell, Stanley R., Green, Damian J., Spencer, Andrew, Furlan, Scott N. and Hill, Geoffrey R. (2024). TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies. Science Immunology, 9 (94) eadg1094, eadg1094. doi: 10.1126/sciimmunol.adg1094

TIM-3<SUP>+</SUP> CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies

2024

Journal Article

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

Takahashi, Shuichiro, Minnie, Simone A., Ensbey, Kathleen S., Schmidt, Christine R., Sekiguchi, Tomoko, Legg, Samuel R. W., Zhang, Ping, Koyama, Motoko, Olver, Stuart D., Collinge, Alika D., Keshmiri, Sara, Comstock, Melissa L., Varelias, Antiopi, Green, Damian J. and Hill, Geoffrey R. (2024). Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation. Blood, 143 (16), 1656-1669. doi: 10.1182/blood.2023022000

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

2024

Journal Article

IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation

Zhang, Ping, Fleming, Peter, Andoniou, Christopher E., Waltner, Olivia G., Bhise, Shruti S., Martins, Jose Paulo, McEnroe, Benjamin A., Voigt, Valentina, Daly, Sheridan, Kuns, Rachel D., Ekwe, Adaeze P., Henden, Andrea S., Saldan, Alda, Olver, Stuart, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Minnie, Simone A., Gradwell, Mark, Wagenaar, Irma, Clouston, Andrew D., Koyama, Motoko, Furlan, Scott N., Kennedy, Glen A., Ward, E Sally, Degli-Esposti, Mariapia A. ... Tey, Siok-Keen (2024). IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation. Journal of Clinical Investigation, 134 (7) e174184, 1-15. doi: 10.1172/jci174184

IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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