Skip to menu Skip to content Skip to footer

2025

Journal Article

CellPhoneDB v5: inferring cell–cell communication from single-cell multiomics data

Troulé, Kevin, Petryszak, Robert, Cakir, Batuhan, Cranley, James, Harasty, Alicia, Prete, Martin, Tuong, Zewen Kelvin, Teichmann, Sarah A., Garcia-Alonso, Luz and Vento-Tormo, Roser (2025). CellPhoneDB v5: inferring cell–cell communication from single-cell multiomics data. Nature Protocols 6619, 1-29. doi: 10.1038/s41596-024-01137-1

CellPhoneDB v5: inferring cell–cell communication from single-cell multiomics data

2025

Journal Article

Temporal profiling of human lymphoid tissues reveals coordinated defense against viral challenge

Coates, Matthew L., Richoz, Nathan, Tuong, Zewen K., Bowyer, Georgina S., Lee, Colin Y. C., Ferdinand, John R., Gillman, Eleanor, McClure, Mark, Dratva, Lisa, Teichmann, Sarah A., Jayne, David R., Di Marco Barros, Rafael, Stewart, Benjamin J. and Clatworthy, Menna R. (2025). Temporal profiling of human lymphoid tissues reveals coordinated defense against viral challenge. Nature Immunology, 26 (2) 838328, 215-229. doi: 10.1038/s41590-024-02064-9

Temporal profiling of human lymphoid tissues reveals coordinated defense against viral challenge

2025

Journal Article

Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR

Lam, Pui Yeng, Omer, Natacha, Wong, Josh K. M., Tu, Cui, Alim, Louisa, Rossi, Gustavo R., Victorova, Maria, Tompkins, Hannah, Lin, Cheng-Yu, Mehdi, Ahmed M., Choo, Amos, Elliott, Melissa R., Coleborn, Elaina, Sun, Jane, Mercer, Timothy, Vittorio, Orazio, Dobson, Lachlan J., Mclellan, Alexander D., Brooks, Andrew, Tuong, Zewen Kelvin, Cheetham, Seth W., Nicholls, Wayne and Souza-Fonseca-Guimaraes, Fernando (2025). Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical and Translational Medicine, 15 (1) e70140, 1-21. doi: 10.1002/ctm2.70140

Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR

2024

Journal Article

An organotypic atlas of human vascular cells

Barnett, Sam N., Cujba, Ana-Maria, Yang, Lu, Maceiras, Ana Raquel, Li, Shuang, Kedlian, Veronika, Pett, J. Patrick, Polanski, Krzysztof, Miranda, Antonio M. A., Xu, Chuan, Cranley, James, Kanemaru, Kazumasa, Lee, Michael, Mach, Lukas, Perera, Shani, Tudor, Catherine, Joseph, Philomeena D., Pritchard, Sophie, Toscano-Rivalta, Rebecca, Tuong, Kelvin, Bolt, Liam, Petryszak, Robert, Prete, Martin, Cakir, Batuhan, Huseynov, Alik, Sarropoulos, Ioannis, Chowdhury, Rasheda A., Elmentaite, Rasa, Madissoon, Elo ... Teichmann, Sarah A. (2024). An organotypic atlas of human vascular cells. Nature Medicine, 30 (12), 1-1. doi: 10.1038/s41591-024-03376-x

An organotypic atlas of human vascular cells

2024

Journal Article

Computational estimation of clonal diversity in autoimmunity

Tuong, Zewen Kelvin, van der Merwe, Rohan, Canete, Pablo F and Roco, Jonathan A (2024). Computational estimation of clonal diversity in autoimmunity. Immunology and Cell Biology, 102 (8), 692-701. doi: 10.1111/imcb.12801

Computational estimation of clonal diversity in autoimmunity

2024

Journal Article

Embracing computational immunology

Cañete, Pablo F and Tuong, Zewen Kelvin (2024). Embracing computational immunology. Immunology & Cell Biology, 102 (8), 663-664. doi: 10.1111/imcb.12817

Embracing computational immunology

2024

Journal Article

Measuring single-cell immune clonality to track haematological cancers

Choo, Amos and Tuong, Zewen Kelvin (2024). Measuring single-cell immune clonality to track haematological cancers. Clinical and Translational Medicine, 14 (8) e1780, e1780. doi: 10.1002/ctm2.1780

Measuring single-cell immune clonality to track haematological cancers

2024

Journal Article

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

Wong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176. doi: 10.1016/j.ebiom.2024.105176

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

2024

Journal Article

Single-cell immune repertoire analysis

Irac, Sergio E., Soon, Megan Sioe Fei, Borcherding, Nicholas and Tuong, Zewen Kelvin (2024). Single-cell immune repertoire analysis. Nature Methods, 21 (5), 777-792. doi: 10.1038/s41592-024-02243-4

Single-cell immune repertoire analysis

2024

Journal Article

Venous-plexus-associated lymphoid hubs support meningeal humoral immunity

Fitzpatrick, Zachary, Ghabdan Zanluqui, Nagela, Rosenblum, Jared S., Tuong, Zewen Kelvin, Lee, Colin Y. C., Chandrashekhar, Vikram, Negro-Demontel, Maria Luciana, Stewart, Andrew P., Posner, David A., Buckley, Monica, Allinson, Kieren S. J., Mastorakos, Panagiotis, Chittiboina, Prashant, Maric, Dragan, Donahue, Danielle, Helmy, Adel, Tajsic, Tamara, Ferdinand, John R., Portet, Anais, Peñalver, Ana, Gillman, Eleanor, Zhuang, Zhengping, Clatworthy, Menna R. and McGavern, Dorian B. (2024). Venous-plexus-associated lymphoid hubs support meningeal humoral immunity. Nature, 628 (8008) s41586-024-07202-9, 612-619. doi: 10.1038/s41586-024-07202-9

Venous-plexus-associated lymphoid hubs support meningeal humoral immunity

2024

Journal Article

Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity

Dean, Isaac, Lee, Colin Y. C., Tuong, Zewen K., Li, Zhi, Tibbitt, Christopher A., Willis, Claire, Gaspal, Fabrina, Kennedy, Bethany C., Matei-Rascu, Veronika, Fiancette, Rémi, Nordenvall, Caroline, Lindforss, Ulrik, Baker, Syed Murtuza, Stockmann, Christian, Sexl, Veronika, Hammond, Scott A., Dovedi, Simon J., Mjösberg, Jenny, Hepworth, Matthew R., Carlesso, Gianluca, Clatworthy, Menna R. and Withers, David R. (2024). Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity. Nature Communications, 15 (1) 683, 1-18. doi: 10.1038/s41467-024-44789-z

Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity

2024

Journal Article

Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity

Lee, Colin Y. C., Kennedy, Bethany C., Richoz, Nathan, Dean, Isaac, Tuong, Zewen K., Gaspal, Fabrina, Li, Zhi, Willis, Claire, Hasegawa, Tetsuo, Whiteside, Sarah K., Posner, David A., Carlesso, Gianluca, Hammond, Scott A., Dovedi, Simon J., Roychoudhuri, Rahul, Withers, David R. and Clatworthy, Menna R. (2024). Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity. Nature Communications, 15 (1) 682, 1-18. doi: 10.1038/s41467-024-44787-1

Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity

2023

Journal Article

Early human lung immune cell development and its role in epithelial cell fate

Barnes, Josephine L., Yoshida, Masahiro, He, Peng, Worlock, Kaylee B., Lindeboom, Rik G. H., Suo, Chenqu, Pett, J. Patrick, Wilbrey-Clark, Anna, Dann, Emma, Mamanova, Lira, Richardson, Laura, Polanski, Krzysztof, Pennycuick, Adam, Allen-Hyttinen, Jessica, Herczeg, Iván T., Arzili, Romina, Hynds, Robert E., Teixeira, Vitor H., Haniffa, Muzlifah, Lim, Kyungtae, Sun, Dawei, Rawlins, Emma L., Oliver, Amanda J., Lyons, Paul A., Marioni, John C., Ruhrberg, Christiana, Tuong, Zewen Kelvin, Clatworthy, Menna R., Reading, James L. ... Nikolić, Marko Z. (2023). Early human lung immune cell development and its role in epithelial cell fate. Science Immunology, 8 (90) eadf9988, 1-18. doi: 10.1126/sciimmunol.adf9988

Early human lung immune cell development and its role in epithelial cell fate

2023

Journal Article

Tissue-resident B cells orchestrate macrophage polarisation and function

Suchanek, Ondrej, Ferdinand, John R., Tuong, Zewen K., Wijeyesinghe, Sathi, Chandra, Anita, Clauder, Ann-Katrin, Almeida, Larissa N., Clare, Simon, Harcourt, Katherine, Ward, Christopher J., Bashford-Rogers, Rachael, Lawley, Trevor, Manz, Rudolf A., Okkenhaug, Klaus, Masopust, David and Clatworthy, Menna R. (2023). Tissue-resident B cells orchestrate macrophage polarisation and function. Nature Communications, 14 (1) 7081, 1-20. doi: 10.1038/s41467-023-42625-4

Tissue-resident B cells orchestrate macrophage polarisation and function

2023

Journal Article

Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality

Kang, Hao, Sun, Hongjian, Yang, Yang, Tuong, Zewen K., Shu, Minglei, Wei, Yunbo, Zhang, Yu, Yu, Di and Tao, Yong (2023). Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality. Clinical and Translational Immunology, 12 (9) e1461, 1-17. doi: 10.1002/cti2.1461

Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality

2023

Journal Article

Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly

Ferreira, Isabella A.T.M., Lee, Colin Y.C., Foster, William S., Abdullahi, Adam, Dratva, Lisa M., Tuong, Zewen Kelvin, Stewart, Benjamin J., Ferdinand, John R., Guillaume, Stephane M., Potts, Martin O.P., Perera, Marianne, Krishna, Benjamin A., Peñalver, Ana, Cabantous, Mia, Kemp, Steven A., Ceron-Gutierrez, Lourdes, Ebrahimi, Soraya, Lyons, Paul, Smith, Kenneth G.C., Bradley, John, Collier, Dami A., McCoy, Laura E., van der Klaauw, Agatha, Thaventhiran, James E.D., Farooqi, I. Sadaf, Teichmann, Sarah A., MacAry, Paul A., Doffinger, Rainer, Wills, Mark R. ... Gupta, Ravindra K. (2023). Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly. Cell Reports, 42 (8) 112991, 112991. doi: 10.1016/j.celrep.2023.112991

Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly

2023

Journal Article

A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss

Wei, Fei, Tuong, Zewen Kelvin, Omer, Mahmoud, Ngo, Christopher, Asiatico, Jackson, Kinzel, Michael, Pugazhendhi, Abinaya Sindu, Khaled, Annette R., Ghosh, Ranajay and Coathup, Melanie (2023). A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss. Bone Research, 11 (1) 34, 1-20. doi: 10.1038/s41413-023-00273-w

A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss

2023

Journal Article

Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis (vol 7, e159751, 2022)

Richoz, Nathan, Tuong, Zewen K., Loudon, Kevin W., Patino-Martinez, Eduardo, Ferdinand, John R., Portet, Anais, Romo-Tena, Jorge, Bashant, Kathleen R., Thevenon, Emeline, Rucci, Francesca, Hoyler, Thomas, Junt, Tobias, Kaplan, Mariana J., Siegel, Richard M. and Clatworthy, Menna R. (2023). Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis (vol 7, e159751, 2022). Jci Insight, 8 (10) e171762. doi: 10.1172/jci.insight.171762

Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis (vol 7, e159751, 2022)

2023

Journal Article

Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins

Suo, Chenqu, Polanski, Krzysztof, Dann, Emma, Lindeboom, Rik G. H., Vilarrasa-Blasi, Roser, Vento-Tormo, Roser, Haniffa, Muzlifah, Meyer, Kerstin B., Dratva, Lisa M., Tuong, Zewen Kelvin, Clatworthy, Menna R. and Teichmann, Sarah A. (2023). Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins. Nature Biotechnology, 42 (1), 40-51. doi: 10.1038/s41587-023-01734-7

Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins

2023

Journal Article

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells

Inaba, Akimichi, Tuong, Zewen Kelvin, Zhao, Tian X., Stewart, Andrew P., Mathews, Rebeccah, Truman, Lucy, Sriranjan, Rouchelle, Kennet, Jane, Saeb-Parsy, Kourosh, Wicker, Linda, Waldron-Lynch, Frank, Cheriyan, Joseph, Todd, John A., Mallat, Ziad and Clatworthy, Menna R. (2023). Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells. Nature Communications, 14 (1) 2071, 1-11. doi: 10.1038/s41467-023-37424-w

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells