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2022 Journal Article Genome-wide identification of the genetic basis of amyotrophic lateral sclerosisZhang, Sai, Cooper-Knock, Johnathan, Weimer, Annika K., Shi, Minyi, Moll, Tobias, Marshall, Jack N.G., Harvey, Calum, Nezhad, Helia Ghahremani, Franklin, John, Souza, Cleide dos Santos, Ning, Ke, Wang, Cheng, Li, Jingjing, Dilliott, Allison A., Farhan, Sali, Elhaik, Eran, Pasniceanu, Iris, Livesey, Matthew R., Eitan, Chen, Hornstein, Eran, Kenna, Kevin P., Blair, Ian, Wray, Naomi R., Kiernan, Matthew, Mitne Neto, Miguel, Chio, Adriano, Cauchi, Ruben, Robberecht, Wim, van Damme, Philip ... Snyder, Michael P. (2022). Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis. Neuron, 110 (6), 992-1008. doi: 10.1016/j.neuron.2021.12.019 |
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2022 Journal Article Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depressionKiewa, Jacqueline, Meltzer‐Brody, Samantha, Milgrom, Jeanette, Guintivano, Jerry, Hickie, Ian B., Whiteman, David C., Olsen, Catherine M., Colodro‐Conde, Lucía, Medland, Sarah E., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2022). Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression. Depression and Anxiety, 39 (3), 182-191. doi: 10.1002/da.23232 |
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2022 Journal Article Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALSHop, Paul J., Zwamborn, Ramona A.J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J.F.A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H.P., van Eijk, Kristel R., Moisse, Matthieu, Baird, Denis, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14 (633) eabj0264, 1-15. doi: 10.1126/scitranslmed.abj0264 |
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2022 Journal Article Methylome-wide association study of early life stressors and adult mental healthHoward, David M., Pain, Oliver, Arathimos, Ryan, Barbu, Miruna C., Amador, Carmen, Walker, Rosie M., Jermy, Bradley, Adams, Mark J., Deary, Ian J., Porteous, David, Campbell, Archie, Sullivan, Patrick F., Evans, Kathryn L., Arseneault, Louise, Wray, Naomi R., Meaney, Michael, McIntosh, Andrew M. and Lewis, Cathryn M. (2022). Methylome-wide association study of early life stressors and adult mental health. Human Molecular Genetics, 31 (4), 651-664. doi: 10.1093/hmg/ddab274 |
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2022 Journal Article Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factorsMullins, Niamh, Kang, JooEun, Campos, Adrian I., Coleman, Jonathan R I, Edwards, Alexis C., Galfalvy, Hanga, Levey, Daniel F., Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J., Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D., Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B., Bergen, Andrew W., Berrettini, Wade H., Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J., Chen, Hsi-Chung ... Ruderfer, Douglas M. (2022). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors. Biological Psychiatry, 91 (3), 313-327. doi: 10.1016/j.biopsych.2021.05.029 |
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2022 Journal Article Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biologyvan Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2022). Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 54 (3), 361-361. doi: 10.1038/s41588-022-01020-3 |
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2022 Journal Article Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression StudyCampos, Adrian I., Byrne, Enda M., Mitchell, Brittany L., Wray, Naomi R., Lind, Penelope A., Licinio, Julio, Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2022). Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study. The Pharmacogenomics Journal, 22 (2), 130-135. doi: 10.1038/s41397-022-00267-7 |
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2022 Journal Article Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1Restuadi, Restuadi, Steyn, Frederik J., Kabashi, Edor, Ngo, Shyuan T., Cheng, Fei-Fei, Nabais, Marta F., Thompson, Mike J., Qi, Ting, Wu, Yang, Henders, Anjali K., Wallace, Leanne, Bye, Chris R., Turner, Bradley J., Ziser, Laura, Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Schultz, David, Kiernan, Matthew C., van Rheenen, Wouter, van den Berg, Leonard H., Veldink, Jan H., Ophoff, Roel, Gusev, Alexander, Zaitlen, Noah, McRae, Allan F., Henderson, Robert D., Wray, Naomi R., Giacomotto, Jean and Garton, Fleur C. (2022). Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. Genome Medicine, 14 (1) 7, 7. doi: 10.1186/s13073-021-01006-6 |
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2021 Journal Article Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biologyvan Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1 |
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2021 Journal Article Autism-related dietary preferences mediate autism-gut microbiome associationsYap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2021). Autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 184 (24), 5916-5931.e17. doi: 10.1016/j.cell.2021.10.015 |
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2021 Journal Article Understanding genetic risk factors for common side effects of antidepressant medicationsCampos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8 |
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2021 Journal Article The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypesMitchell, Brittany L., Campos, Adrian I., Whiteman, David C., Olsen, Catherine M., Gordon, Scott D., Walker, Adam J., Dean, Olivia M., Berk, Michael, Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G. and Byrne, Enda M. (2021). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92 (3), 227-235. doi: 10.1016/j.biopsych.2021.10.021 |
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2021 Journal Article A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohortsNi, Guiyan, Zeng, Jian, Revez, Joana A., Wang, Ying, Zheng, Zhili, Ge, Tian, Restuadi, Restuadi, Kiewa, Jacqueline, Nyholt, Dale R., Coleman, Jonathan R.I., Smoller, Jordan W., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2021). A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. Biological Psychiatry, 90 (9), 611-620. doi: 10.1016/j.biopsych.2021.04.018 |
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2021 Journal Article Polygenic burden could explain high rates of affective disorders in a community with restricted founder populationWang, Xiaotong, Lin, Tian, Yengo, Loic, Sidorenko, Julia, Wray, Naomi R. and Levinson, Douglas F. (2021). Polygenic burden could explain high rates of affective disorders in a community with restricted founder population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (6), 367-375. doi: 10.1002/ajmg.b.32876 |
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2021 Journal Article Seven short reflections on the notion of schizophreniaMcGrath, John J. and Wray, Naomi R. (2021). Seven short reflections on the notion of schizophrenia. Schizophrenia Research, 242, 96-97. doi: 10.1016/j.schres.2021.09.026 |
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2021 Journal Article MiNDAUS partnership: a roadmap for the cure and management of motor Neurone diseaseVucic, Steve, Wray, Naomi, Henders, Anjali, Henderson, Robert D., Talman, Paul, Mathers, Susan, Bellgard, Matthew, Aoun, Samar, Birks, Carol, Thomas, Gethin, Hansen, Catherine, Thomas, Geoff, Hogden, Anne, Needham, Merrilee, Schultz, David, Soulis, Tina, Sheean, Bec, Milne, Jane, Rowe, Dominic, Zoing, Margie and Kiernan, Matthew C (2021). MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1980889 |
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2021 Journal Article Discovery and implications of polygenicity of common diseasesVisscher, Peter M., Yengo, Loic, Cox, Nancy J. and Wray, Naomi R. (2021). Discovery and implications of polygenicity of common diseases. Science, 373 (6562), 1468-1473. doi: 10.1126/science.abi8206 |
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2021 Journal Article Genomic and phenotypic insights from an atlas of genetic effects on DNA methylationMin, Josine L., Hemani, Gibran, Hannon, Eilis, Dekkers, Koen F., Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J., Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D., Richardson, Tom G., Klughammer, Johanna, Iotchkova, Valentina, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, McArdle, Wendy L., Ho, Karen M., Kumar, Ashish, Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Kazmi, Nabila, Mason, Dan, McRae, Allan F., Corcoran, David L., Sugden, Karen ... BIOS Consortium (2021). Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53 (9), 1311-1321. doi: 10.1038/s41588-021-00923-x |
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2021 Journal Article Investigating shared genetic basis across tourette syndrome and comorbid neurodevelopmental disorders along the impulsivity-compulsivity spectrumYang, Zhiyu, Wu, Hanrui, Lee, Phil H., Tsetsos, Fotis, Davis, Lea K., Yu, Dongmei, Lee, Sang Hong, Dalsgaard, Søren, Haavik, Jan, Barta, Csaba, Zayats, Tetyana, Eapen, Valsamma, Wray, Naomi R., Devlin, Bernie, Daly, Mark, Neale, Benjamin, Børglum, Anders D., Crowley, James J., Scharf, Jeremiah, Mathews, Carol A., Faraone, Stephen V., Franke, Barbara, Mattheisen, Manuel, Smoller, Jordan W. and Paschou, Peristera (2021). Investigating shared genetic basis across tourette syndrome and comorbid neurodevelopmental disorders along the impulsivity-compulsivity spectrum. Biological Psychiatry, 90 (5), 317-327. doi: 10.1016/j.biopsych.2020.12.028 |
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2021 Journal Article Polygenic risk scores derived from varying definitions of depression and risk of depressionMitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988 |
