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2017

Journal Article

Glutathione responsive polymers and their application in drug delivery systems

Quinn, John F., Whittaker, Michael R. and Davis, Thomas P. (2017). Glutathione responsive polymers and their application in drug delivery systems. Polymer Chemistry, 8 (1), 97-126. doi: 10.1039/c6py01365a

Glutathione responsive polymers and their application in drug delivery systems

2017

Journal Article

Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate)-peptide conjugates prepared by aqueous Cu(0)-mediated polymerization and reductive amination

Collins, Jennifer, Wallis, Sacha J., Simula, Alexandre, Whittaker, Michael R., McIntosh, Michelle P., Wilson, Paul, Davis, Thomas P., Haddleton, David M. and Kempe, Kristian (2017). Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate)-peptide conjugates prepared by aqueous Cu(0)-mediated polymerization and reductive amination. Macromolecular Rapid Communications, 38 (2) 1600534, 1600534. doi: 10.1002/marc.201600534

Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate)-peptide conjugates prepared by aqueous Cu(0)-mediated polymerization and reductive amination

2017

Book Chapter

Nanotechnology in medical research

Mansfeld, F. M., Davis, T. P. and Kavallaris, M. (2017). Nanotechnology in medical research. Micro- and nanotechnology in vaccine development. (pp. 21-45) edited by Mariusz Skwarczynski and Istvan Toth. Kidlington, Oxford, United States: William Andrew. doi: 10.1016/B978-0-323-39981-4.00002-6

Nanotechnology in medical research

2016

Journal Article

Well-defined PDMAEA stars via Cu(0)-mediated reversible deactivation radical polymerization

Whitfield, Richard, Anastasaki, Athina, Truong, Nghia P., Wilson, Paul, Kempe, Kristian, Burns, James A., Davis, Thomas P. and Haddleton, David M. (2016). Well-defined PDMAEA stars via Cu(0)-mediated reversible deactivation radical polymerization. Macromolecules, 49 (23), 8914-8924. doi: 10.1021/acs.macromol.6b01511

Well-defined PDMAEA stars via Cu(0)-mediated reversible deactivation radical polymerization

2016

Journal Article

Cationic acrylate oligomers comprising amino acid mimic moieties demonstrate improved antibacterial killing efficiency

Grace, James L., Elliott, Alysha G., Huang, Johnny X., Schneider, Elena K., Truong, Nghia P., Cooper, Matthew A., Li, Jian, Davis, Thomas P., Quinn, John F., Velkov, Tony and Whittaker, Michael R. (2016). Cationic acrylate oligomers comprising amino acid mimic moieties demonstrate improved antibacterial killing efficiency. Journal of Materials Chemistry B, 5 (3), 531-536. doi: 10.1039/C6TB02787C

Cationic acrylate oligomers comprising amino acid mimic moieties demonstrate improved antibacterial killing efficiency

2016

Journal Article

Stability enhancing N-terminal PEGylation of oxytocin exploiting different polymer architectures and conjugation approaches

Collins, Jennifer, Kempe, Kristian, Wilson, Paul, Blindauer, Claudia A., McIntosh, Michelle P., Davis, Thomas P., Whittaker, Michael R. and Haddleton, David M. (2016). Stability enhancing N-terminal PEGylation of oxytocin exploiting different polymer architectures and conjugation approaches. Biomacromolecules, 17 (8), 2755-2766. doi: 10.1021/acs.biomac.6b00919

Stability enhancing N-terminal PEGylation of oxytocin exploiting different polymer architectures and conjugation approaches

2016

Journal Article

A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo

Teo, Joann, McCarroll, Joshua A., Boyer, Cyrille, Youkhana, Janet, Sagnella, Sharon M., Duong, Hien T. T., Liu, Jie, Sharbeen, George, Goldstein, David, Davis, Thomas P., Kavallaris, Maria and Phillips, Phoebe A. (2016). A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo. Biomacromolecules, 17 (7), 2337-2351. doi: 10.1021/acs.biomac.6b00185

A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo

2016

Journal Article

Star polymers

Ren, Jing M., McKenzie, Thomas G., Fu, Qiang, Wong, Edgar H. H., Xu, Jiangtao, An, Zesheng, Shanmugam, Sivaprakash, Davis, Thomas P., Boyer, Cyrille and Qiao, Greg G. (2016). Star polymers. Chemical Reviews, 116 (12), 6743-6836. doi: 10.1021/acs.chemrev.6b00008

Star polymers

2016

Journal Article

Nitric oxide (NO) endows arylamine-containing block copolymers with unique photoresponsive and switchable LCST properties

Hu, Jinming, Whittaker, Michael R., Quinn, John F. and Davis, Thomas P. (2016). Nitric oxide (NO) endows arylamine-containing block copolymers with unique photoresponsive and switchable LCST properties. Macromolecules, 49 (7), 2741-2749. doi: 10.1021/acs.macromol.6b00054

Nitric oxide (NO) endows arylamine-containing block copolymers with unique photoresponsive and switchable LCST properties

2016

Journal Article

Inhibition of hIAPP amyloid aggregation and pancreatic beta-cell toxicity by OH-terminated PAMAM dendrimer

Gurzov, Esteban N., Wang, Bo, Pilkington, Emily H., Chen, Pengyu, Kakinen, Aleksandr, Stanley, William J., Litwak, Sara A., Hanssen, Eric G., Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2016). Inhibition of hIAPP amyloid aggregation and pancreatic beta-cell toxicity by OH-terminated PAMAM dendrimer. Small, 12 (12), 1615-1626. doi: 10.1002/smll.201502317

Inhibition of hIAPP amyloid aggregation and pancreatic beta-cell toxicity by OH-terminated PAMAM dendrimer

2016

Journal Article

Pancreatic beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species

Pilkington, Emily H., Gurzov, Esteban N., Kakinen, Aleksandr, Litwak, Sara A., Stanley, William J., Davis, Thomas P. and Ke, Pu Chun (2016). Pancreatic beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species. Scientific Reports, 6 (1) 21274. doi: 10.1038/srep21274

Pancreatic beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species

2016

Journal Article

Cu(0)-mediated living radical polymerization: a versatile tool for materials synthesis

Anastasaki, Athina, Nikolaou, Vasiliki, Nurumbetov, Gabit, Wilson, Paul, Kempe, Kristian, Quinn, John F., Davis, Thomas P., Whittaker, Michael R. and Haddleton, David M. (2016). Cu(0)-mediated living radical polymerization: a versatile tool for materials synthesis. Chemical Reviews, 116 (3), 835-877. doi: 10.1021/acs.chemrev.5b00191

Cu(0)-mediated living radical polymerization: a versatile tool for materials synthesis

2016

Journal Article

Stabilizing off-pathway oligomers by polyphenol nanoassemblies for IAPP aggregation inhibition

Nedumpully-Govindan, Praveen, Kakinen, Aleksandr, Pilkington, Emily H., Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2016). Stabilizing off-pathway oligomers by polyphenol nanoassemblies for IAPP aggregation inhibition. Scientific Reports, 6 (1) 19463. doi: 10.1038/srep19463

Stabilizing off-pathway oligomers by polyphenol nanoassemblies for IAPP aggregation inhibition

2016

Journal Article

Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells

Nedumpully-Govindan, Praveen, Gurzov, Esteban N., Chen, Pengyu, Pilkington, Emily H., Stanley, William J., Litwak, Sara A., Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2016). Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells. Physical Chemistry Chemical Physics, 18 (1), 94-100. doi: 10.1039/c5cp05924k

Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells

2016

Journal Article

The pharmacokinetics and biodistribution of a 64 kDa PolyPEG star polymer after subcutaneous and pulmonary administration to rats

Khor, Song Yang, Hu, Jinming, McLeod, Victoria M., Quinn, John F., Porter, Christopher J. H., Whittaker, Michael R., Kaminskas, Lisa M. and Davis, Thomas P. (2016). The pharmacokinetics and biodistribution of a 64 kDa PolyPEG star polymer after subcutaneous and pulmonary administration to rats. Journal of Pharmaceutical Sciences, 105 (1), 293-300. doi: 10.1016/j.xphs.2015.11.038

The pharmacokinetics and biodistribution of a 64 kDa PolyPEG star polymer after subcutaneous and pulmonary administration to rats

2016

Journal Article

Macromolecular hydrogen sulfide donors trigger spatiotemporally confined changes in cell signaling

Ercole, Francesca, Mansfeld, Friederike M., Kavallaris, Maria, Whittaker, Michael R., Quinn, John F., Halls, Michelle L. and Davis, Thomas P. (2016). Macromolecular hydrogen sulfide donors trigger spatiotemporally confined changes in cell signaling. Biomacromolecules, 17 (1), 371-383. doi: 10.1021/acs.biomac.5b01469

Macromolecular hydrogen sulfide donors trigger spatiotemporally confined changes in cell signaling

2016

Journal Article

Facile access to thermoresponsive filomicelles with tuneable cores

Truong, Nghia P., Quinn, John F., Anastasaki, Athina, Haddleton, David M., Whittaker, Michael R. and Davis, Thomas P. (2016). Facile access to thermoresponsive filomicelles with tuneable cores. Chemical Communications, 52 (24), 4497-4500. doi: 10.1039/c6cc00900j

Facile access to thermoresponsive filomicelles with tuneable cores

2016

Journal Article

Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

Wang, Bo, Blin, Thomas, Kakinen, Aleksandr, Ge, Xinwei, Pilkington, Emily H., Quinn, John F., Whittaker, Michael R., Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2016). Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding. Polymer Chemistry, 7 (45), 6875-6879. doi: 10.1039/c6py01480a

Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

2016

Journal Article

Antibacterial low molecular weight cationic polymers: Dissecting the contribution of hydrophobicity, chain length and charge to activity

Grace, James L., Huang, Johnny X., Cheah, Soon-Ee, Truong, Nghia P., Cooper, Matthew A., Li, Jian, Davis, Thomas P., Quinn, John F., Velkov, Tony and Whittaker, Michael R. (2016). Antibacterial low molecular weight cationic polymers: Dissecting the contribution of hydrophobicity, chain length and charge to activity. RSC Advances, 6 (19), 15469-15477. doi: 10.1039/c5ra24361k

Antibacterial low molecular weight cationic polymers: Dissecting the contribution of hydrophobicity, chain length and charge to activity

2016

Journal Article

Gadolinium-functionalized nanoparticles for application as magnetic resonance imaging contrast agents via polymerization-induced self-assembly

Esser, Lars, Truong, Nghia P., Karagoz, Bunyamin, Moffat, Bradford A., Boyer, Cyrille, Quinn, John F., Whittaker, Michael R. and Davis, Thomas P. (2016). Gadolinium-functionalized nanoparticles for application as magnetic resonance imaging contrast agents via polymerization-induced self-assembly. Polymer Chemistry, 7 (47), 7325-7337. doi: 10.1039/c6py01797e

Gadolinium-functionalized nanoparticles for application as magnetic resonance imaging contrast agents via polymerization-induced self-assembly