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2025 Journal Article Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetesCao, Yuanzhao, Redd, Meredith, Outhwaite, Jennifer, Mizikovsky, Dalia, Shim, Woo Jun, Fang, Chen, Wu, Zhixuan, Daygon, Dara, Stark, Terra, Palfreyman, Robin, Chiu, Han Sheng, Tan, Clarissa, Thomas, Ulrich, Dragicevic, Elena, Sng, Julian, Barrett, Helen, Dorey, Emily, Shah, Sonia, Short, Kirsty and Palpant, Nathan J. (2025). Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes. doi: 10.1101/2025.01.29.635173 |
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2024 Journal Article A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cellsChow, Chris Siu Yeung, Negi, Sumedha, Bao, Shaine, Fang, Chen, Hudson, James, Shim, Woo Jun, Yuanzhao Cao and Palpant, Nathan (2024). A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cells. doi: 10.1101/2024.09.04.611313 |
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2023 Journal Article New drug targets and preclinical modelling recommendations for treating acute myocardial infarctionCao, Yuanzhao, Redd, Meredith A., Fang, Chen, Mizikovsky, Dalia, Li, Xichun, Macdonald, Peter S., King, Glenn F. and Palpant, Nathan J. (2023). New drug targets and preclinical modelling recommendations for treating acute myocardial infarction. Heart, Lung and Circulation, 32 (7), 852-869. doi: 10.1016/j.hlc.2022.12.015 |
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2024 Journal Article Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionSinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z |
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2024 Journal Article High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venomsKramer, Simon, Kotapati, Charan, Cao, Yuanzhao, Fry, Bryan G., Palpant, Nathan J., King, Glenn F. and Cardoso, Fernanda C. (2024). High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms. Toxicon: X, 21 100184. doi: 10.1016/j.toxcx.2024.100184 |
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Featured 2024 Journal Article Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesodermWu, Zhixuan, Shen, Sophie, Mizikovsky, Dalia, Cao, Yuanzhao, Naval-Sanchez, Marina, Tan, Siew Zhuan, Alvarez, Yanina D., Sun, Yuliangzi, Chen, Xiaoli, Zhao, Qiongyi, Kim, Daniel, Yang, Pengyi, Hill, Timothy A., Jones, Alun, Fairlie, David P., Pébay, Alice, Hewitt, Alex W., Tam, Patrick P.L., White, Melanie D., Nefzger, Christian M. and Palpant, Nathan J. (2024). Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm. Developmental Cell, 59 (6), 705-722.e8. doi: 10.1016/j.devcel.2024.01.019 |
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Featured 2023 Journal Article HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and functionFriedman, Clayton E., Cheetham, Seth W., Negi, Sumedha, Mills, Richard J., Ogawa, Masahito, Redd, Meredith A., Chiu, Han Sheng, Shen, Sophie, Sun, Yuliangzi, Mizikovsky, Dalia, Bouveret, Romaric, Chen, Xiaoli, Voges, Holly K., Paterson, Scott, De Angelis, Jessica E., Andersen, Stacey B., Cao, Yuanzhao, Wu, Yang, Jafrani, Yohaann M.A., Yoon, Sohye, Faulkner, Geoffrey J., Smith, Kelly A., Porrello, Enzo, Harvey, Richard P., Hogan, Benjamin M., Nguyen, Quan, Zeng, Jian, Kikuchi, Kazu, Hudson, James E. and Palpant, Nathan J. (2023). HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function. Developmental Cell, 59 (1), 91-107.e1. doi: 10.1016/j.devcel.2023.11.012 |
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2022 Journal Article The ins and outs of cellular pH during cardiac ischemiaCao, Yuanzhao and Palpant, Nathan J. (2022). The ins and outs of cellular pH during cardiac ischemia. Journal of Molecular and Cellular Cardiology, 174, 133-134. doi: 10.1016/j.yjmcc.2022.12.004 |
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2015 Journal Article Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation siteLu, Jiaqi, Cheng, Kuoyuan, Zhang, Bo, Xu, Huan, Cao, Yuanzhao, Guo, Fei, Feng, Xudong and Xia, Qing (2015). Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site. Free Radical Biology and Medicine, 85, 114-126. doi: 10.1016/j.freeradbiomed.2015.04.011 |
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2015 Journal Article Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy statusLu, Jiaqi, Cao, Yuanzhao, Cheng, Kuoyuan, Xu, Bo, Wang, Tianchang, Yang, Qi, Yang, Qin, Feng, Xudong and Xia, Qing (2015). Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status. Experimental Cell Research, 334 (2), 194-206. doi: 10.1016/j.yexcr.2015.04.006 |
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2015 Journal Article MnTM-4-PyP modulates endogenous antioxidant responses and protects primary cortical neurons against oxidative stressCheng, Kuo-Yuan, Guo, Fei, Lu, Jia-Qi, Cao, Yuan-Zhao, Wang, Tian-Chang, Yang, Qi and Xia, Qing (2015). MnTM-4-PyP modulates endogenous antioxidant responses and protects primary cortical neurons against oxidative stress. CNS Neuroscience and Therapeutics, 21 (5), 435-445. doi: 10.1111/cns.12373 |
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2014 Journal Article AMPK activation regulates neuronal structure in developing hippocampal neuronsRamamurthy, S., Chang, E., Cao, Y., Zhu, J. and Ronnett, G. V. (2014). AMPK activation regulates neuronal structure in developing hippocampal neurons. Neuroscience, 259, 13-24. doi: 10.1016/j.neuroscience.2013.11.048 |
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2012 Journal Article Neuroprotection by manganese superoxide dismutase (MnSOD) mimics: antioxidant effect and oxidative stress regulation in acute experimental strokeHuang, Hai-Feng, Guo, Fei, Cao, Yuan-Zhao, Shi, Wen and Xia, Qing (2012). Neuroprotection by manganese superoxide dismutase (MnSOD) mimics: antioxidant effect and oxidative stress regulation in acute experimental stroke. CNS Neuroscience and Therapeutics, 18 (10), 811-818. doi: 10.1111/j.1755-5949.2012.00380.x |
