
Overview
Background
Dr. Mohd Hafiz Abdul-Aziz is an Early Career Research Fellow and Clinical Research Pharmacist at the University of Queensland Centre for Clinical Research (UQCCR), Australia. He currently leads the Clinical Dosing Studies and Knowledge Translation Workstream within the Antimicrobial Optimisation Group and the Centre for Research Excellence for Personalising Antimicrobial Dosing to Reduce Resistance (CRE RESPOND) at UQCCR. Dr. Abdul-Aziz holds a Bachelor of Pharmacy (IIUM) and a Master of Clinical Pharmacy (UKM) from Malaysia and completed his PhD at the University of Queensland in 2016. His doctoral thesis focused on pharmacokinetic/pharmacodynamic-optimised beta-lactam dosing in critically ill patients.
As a clinical pharmacist with a strong interest in clinical research, Dr. Abdul-Aziz is particularly focused on multi-centre and multi-national collaborations. His current research program aims to develop innovative methods for optimising antimicrobial dosing and delivery to improve patient outcomes in the ICU. He has extensive experience in designing and conducting multi-national clinical pharmacokinetic studies in the ICU. Over the past five years, he has led or coordinated eight multi-national antimicrobial pharmacokinetic studies, including the ASAP ECMO, BLING 3, BLING 3 PK/PD, and PNEUDOS studies.
Dr. Abdul-Aziz is a Fellow of the International Society of Antimicrobial Chemotherapy (ISAC) and serves as the Chair of the Infections in the ICU and Sepsis Working Group of ISAC. He has maintained active collaborations with over 100 collaborators from 36 countries.
Availability
- Dr Hafiz Abdul-Aziz is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Hafiz Abdul-Aziz’s works on UQ eSpace
2023
Journal Article
A systematic review on antimicrobial pharmacokinetic differences between Asian and non-Asian adult populations
Setiawan, Eko, Cotta, Menino Osbert, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2023). A systematic review on antimicrobial pharmacokinetic differences between Asian and non-Asian adult populations. Antibiotics, 12 (5) 803, 1-23. doi: 10.3390/antibiotics12050803
2023
Journal Article
Novel antimicrobial agents for gram-negative pathogens
Karvouniaris, Marios, Almyroudi, Maria Panagiota, Abdul-Aziz, Mohd Hafiz, Blot, Stijn, Paramythiotou, Elisabeth, Tsigou, Evdoxia and Koulenti, Despoina (2023). Novel antimicrobial agents for gram-negative pathogens. Antibiotics, 12 (4) 761, 1-31. doi: 10.3390/antibiotics12040761
2023
Journal Article
Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients
Setiawan, Eko, Cotta, Menino Osbert, Abdul-Aziz, Mohd-Hafiz, Widjanarko, Doddy, Sosilya, Hernycane, Lukas, Dwi Lily, Wallis, Steven C., Parker, Suzanne and Roberts, Jason A. (2023). Population pharmacokinetics and dosing simulations of ampicillin and sulbactam in hospitalised adult patients. Clinical Pharmacokinetics, 62 (4), 1-14. doi: 10.1007/s40262-023-01219-5
2022
Journal Article
Reply to Fillatre, et al. and Li, et al
Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2022). Reply to Fillatre, et al. and Li, et al. American Journal of Respiratory and Critical Care Medicine, 207 (7), 952-953. doi: 10.1164/rccm.202211-2140LE
2022
Conference Publication
Pharmacokinetics of polymyxin B and the pharmacokinetic/pharmacodynamic target attainment in hospitalised adult patients with multidrug-resistant gram-negative infections
Zamri, Puteri Juanita, Abdul-Aziz, Mohd-Hafiz, Hernandez-Mitre, Maria Patricia, Hasan, Mohd Shahnaz, Shariff, Izyani Md, Sulaiman, Helmi, Wallis, Steve, Sumi, Chandra Datta, Sime, Fekade Bruck and Roberts, Jason A (2022). Pharmacokinetics of polymyxin B and the pharmacokinetic/pharmacodynamic target attainment in hospitalised adult patients with multidrug-resistant gram-negative infections. 32nd International Congress of Antimicrobial Chemotherapy (ICC), Perth, Australia, 27-30 November 2022. Amsterdam, Netherlands: Elsevier . doi: 10.1016/s2213-7165(22)00339-3
2022
Book Chapter
Pharmacology
Kirk, Christa Jefferis, Abdul-Aziz, Mohd H., Roberts, Jason A., Valencia, Eleonore, Watt, Kevin, MacLaren, Graeme and Shekar, Kiran (2022). Pharmacology. Extracorporeal life support: The ELSO red book. (pp. 643-654) edited by Graeme Maclaren, Daniel Brodie, Roberto Lorusso, Giles Peek, Ravi Thiagarajan and Leen Vercaemst. Ann Arbor, MI, United States: Extracorporeal Life Support Organization.
2022
Journal Article
Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Levkovich, Bianca J., Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Roberts, Jason A., Shekar, Kiran, Fraser, John F. and ASAP ECMO Investigators (2022). Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Anaesthesia Critical Care and Pain Medicine, 41 (3) 101080, 1-6. doi: 10.1016/j.accpm.2022.101080
2022
Journal Article
Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients
Setiawan, Eko, Abdul-Aziz, Mohd-Hafiz, Cotta, Menino Osbert, Susaniwati, Susaniwati, Cahjono, Heru, Sari, Ika Yunita, Wibowo, Tjipto, Marpaung, Ferdy Royland and Roberts, Jason A. (2022). Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients. Scientific Reports, 12 (1) 8930, 1-11. doi: 10.1038/s41598-022-12627-1
2022
Journal Article
Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: a contemporary, multidisciplinary ESGCIP perspective
Giacobbe, Daniele Roberto, Roberts, Jason A., Abdul-Aziz, Mohd H., de Montmollin, Etienne, Timsit, Jean-François and Bassetti, Matteo (2022). Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: a contemporary, multidisciplinary ESGCIP perspective. Expert Review of Anti-infective Therapy, 20 (7), 1-17. doi: 10.1080/14787210.2022.2063838
2022
Journal Article
Pharmacokinetics and pharmacodynamics of beta-lactam antibiotics in critically ill patients
Sulaiman, Helmi, Roberts, Jason A. and Abdul-Aziz, Mohd H. (2022). Pharmacokinetics and pharmacodynamics of beta-lactam antibiotics in critically ill patients. Farmacia Hospitalaria, 46 (3), 182-190. doi: 10.7399/fh.13170
2022
Journal Article
Hospital-based antimicrobial stewardship programs used in low- and middle-income countries: a scoping review
Setiawan, Eko, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Cotta, Menino Osbert (2022). Hospital-based antimicrobial stewardship programs used in low- and middle-income countries: a scoping review. Microbial Drug Resistance, 28 (5), 566-584. doi: 10.1089/mdr.2021.0363
2022
Journal Article
Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Gilder, Eileen, Kim, Hyung-Sook, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran, Roberts, Jason A. and ASAP ECMO Investigators (2022). Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study). Clinical Pharmacokinetics, 61 (6), 847-856. doi: 10.1007/s40262-021-01106-x
2022
Book Chapter
Challenges of antimicrobial therapy in ECMO patients
Cheng, Vesa, Abdul-Aziz, Mohd H. and Shekar, Kiran (2022). Challenges of antimicrobial therapy in ECMO patients. Extracorporeal membrane oxygenation: an interdisciplinary problem-based learning approach. (pp. 191-200) edited by Marc O. Maybauer. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780197521304.003.0018
2022
Journal Article
Indonesian healthcare providers' perceptions and attitude on antimicrobial resistance, prescription and stewardship programs
Setiawan, Eko, Cotta, Menino O., Abdul-Aziz, Mohd Hafiz, Sosilya, Hernycane, Widjanarko, Doddy, Wardhani, Dian K. and Roberts, Jason A. (2022). Indonesian healthcare providers' perceptions and attitude on antimicrobial resistance, prescription and stewardship programs. Future Microbiology, 17 (5), 363-375. doi: 10.2217/fmb-2021-0193
2022
Journal Article
Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M., Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2022). Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 66 (1) AAC0137721, 1-10. doi: 10.1128/aac.01377-21
2021
Journal Article
Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Jakob, Stephan M., Levkovich, Bianca J., Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Roberts, Jason A., Shekar, Kiran, Fraser, John F. and on behalf ofASAP ECMO Investigators (2021). Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). International Journal of Antimicrobial Agents, 58 (6) 106466, 1-8. doi: 10.1016/j.ijantimicag.2021.106466
2021
Journal Article
Therapeutic drug monitoring of antibiotics: defining the therapeutic range
Abdul–Aziz, Mohd H., Brady, Kara, Cotta, Menino Osbert and Roberts, Jason A. (2021). Therapeutic drug monitoring of antibiotics: defining the therapeutic range. Therapeutic Drug Monitoring, 44 (1), 19-31. doi: 10.1097/ftd.0000000000000940
2021
Journal Article
Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2021). Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 65 (11) e01438-21, 1-11. doi: 10.1128/aac.01438-21
2021
Journal Article
Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report
Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report. International Journal of Antimicrobial Agents, 58 (5) 106431, 106431. doi: 10.1016/j.ijantimicag.2021.106431
2021
Journal Article
Applying antimicrobial pharmacokinetic principles for complex patients: critically ill adult patients receiving extracorporeal membrane oxygenation and renal replacement therapy
Cheng, Vesa, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Applying antimicrobial pharmacokinetic principles for complex patients: critically ill adult patients receiving extracorporeal membrane oxygenation and renal replacement therapy. Current Infectious Disease Reports, 23 (9) 13. doi: 10.1007/s11908-021-00757-y
Funding
Current funding
Past funding
Supervision
Availability
- Dr Hafiz Abdul-Aziz is:
- Available for supervision
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Supervision history
Current supervision
-
Master Philosophy
Determining bEta-lactam Exposure targets in Patients with deep-seated infections.
Associate Advisor
Other advisors: Dr Robert Horvath
-
Master Philosophy
Determining bEta-lactam Exposure targets in Patients with deep-seated infections.
Associate Advisor
Other advisors: Dr Robert Horvath
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Associate Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Professor Jason Roberts
Completed supervision
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Associate Advisor
Other advisors: Dr Fekade Sime, Professor Jason Roberts
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Professor Jason Roberts
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Professor Kiran Shekar, Professor Jason Roberts
Media
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