
Overview
Background
Dr. Mohd Hafiz Abdul-Aziz is an incoming National Health and Medical Research Council (NHMRC) Emerging Leadership Fellow EL2 (2026) and Clinical Research Pharmacist at the University of Queensland Centre for Clinical Research (UQCCR), Australia. He currently leads the Clinical Dosing Studies and Knowledge Translation Workstream within the Antimicrobial Optimisation Group and the Centre for Research Excellence for Personalising Antimicrobial Dosing to Reduce Resistance (CRE RESPOND) at UQCCR. Dr. Abdul-Aziz holds a Bachelor of Pharmacy (IIUM) and a Master of Clinical Pharmacy (UKM) from Malaysia and completed his PhD at the University of Queensland in 2016. His doctoral thesis focused on pharmacokinetic/pharmacodynamic (PK/PD)-optimised beta-lactam dosing in critically ill patients.
As a clinical pharmacist with a strong interest in clinical research, Dr. Abdul-Aziz is particularly focused on multi-centre and multi-national collaborations. His current research program aims to develop innovative methods for optimising antimicrobial dosing and delivery to improve patient outcomes in the ICU. His current areas of interest include: (1) antimicrobial pharmacokinetics/pharmacodynamics (PK/PD); (2) antimicrobial dosing in special patient population groups (e.g. critically ill, pneumonia, extracorporeal membrane oxygenation (ECMO), renal replacement therapy (RRT) patients; (3) prolonged infusions of beta-lactam antibiotics; (4) antimicrobial therapeutic drug monitoring (TDM); (5) ex-vivo pharmacokinetic ECMO and RRT model experiments; (6) model-informed precision antimicrobial dosing; and (7) multi-centre population pharmacokinetic studies. He has authored over 80 peer-reviewed papers and book chapters in this research area. His publications have been cited more than 4800 times. He has extensive experience in designing and conducting multi-national clinical pharmacokinetic studies in the ICU. Over the past five years, he has led or coordinated eight multi-national antimicrobial pharmacokinetic studies, including the ASAP ECMO, BLING 3, BLING 3 PK/PD, and PNEUDOS studies.
Dr. Abdul-Aziz is a Fellow of the International Society of Antimicrobial Chemotherapy (ISAC) and currently serves as the Chair of the Infections in the ICU and Sepsis Working Group of ISAC. He maintains active collaborations with more than 100 researchers across 36 countries.
Information for Potential Students
Dr. Abdul-Aziz welcomes expressions of interest from prospective postgraduate students. Interested applicants are encouraged to contact him via email to discuss potential research opportunities. Please include an up-to-date CV and a brief research proposal outlining the project you wish to undertake. Dr. Abdul-Aziz is also open to developing projects that address research questions specific to your clinical practice, particularly those related to optimising antimicrobial dosing and delivery.
Availability
- Dr Hafiz Abdul-Aziz is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
-
Antimicrobial pharmacokinetics/pharmacodynamics (PK/PD) in critically ill patients
-
Antimicrobial therapeutic drug monitoring (TDM) in the intensive care unit (ICU)
-
Ex-vivo pharmacokinetic ECMO and RRT model experiments
-
Antimicrobial dosing in special patient population groups (e.g. critically ill, pneumonia, extracorporeal membrane oxygenation (ECMO), renal replacement therapy (RRT) patients
-
Prolonged infusions of beta-lactam antibiotics in critically ill patients
-
Model-informed precision antimicrobial dosing in the intensive care unit (ICU)
-
Multi-centre population pharmacokinetic studies
Works
Search Professor Hafiz Abdul-Aziz’s works on UQ eSpace
2015
Journal Article
Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development
Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015). Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 (1), 136-153. doi: 10.1055/s-0034-1398490
2015
Conference Publication
The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting
Abdul-Aziz, M. H., Sulaiman, H., Mat-Nor, M., Rai, V., Wong, K., Hasan, M., Wallis, S., Lipman, J., Staatz, C. E. and Roberts, J. (2015). The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, CA United States, 17-21 September 2015.
2014
Journal Article
Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU
Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 (10), 1380-1384. doi: 10.1177/1060028014540610
2014
Journal Article
Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions
Roberts, Jason A., Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander ., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely, Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula and Kuti, Joseph L. (2014). Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. The Lancet Infectious Diseases, 14 (6), 498-509. doi: 10.1016/S1473-3099(14)70036-2
2014
Conference Publication
Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis
Abdul-Aziz, M., Udy, A., Wallis, S., Roberts, M., Lipman, J. and Roberts, J. (2014). Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis. European Congress of Clinical Microbiology & Infectious Diseases, Barcelona, Spain, 10-13 May 2014.
2013
Journal Article
Defining antibiotic dosing in lung infections
Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Lipman, Jeffrey and Roberts, Jason A. (2013). Defining antibiotic dosing in lung infections. Clinical Pulmonary Medicine, 20 (3), 121-128. doi: 10.1097/CPM.0b013e31828fc646
2012
Journal Article
Continuous beta-lactam infusion in critically ill patients: the clinical evidence
Abdul-Aziz, Mohd H., Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey and Roberts, Jason A. (2012). Continuous beta-lactam infusion in critically ill patients: the clinical evidence. Annals of Intensive Care, 2 (1) 37, 37. doi: 10.1186/2110-5820-2-37
2012
Journal Article
Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics
Abdul-Aziz, Mohd Hafiz, Staatz, C. E., Kirkpatrick, C. M. J., Lipman, J. and Roberts, J. A. (2012). Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics. Minerva Anestesiologica, 78 (1), 94-104.
Funding
Current funding
Past funding
Supervision
Availability
- Dr Hafiz Abdul-Aziz is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Master Philosophy
Determining bEta-lactam Exposure targets in Patients with deep-seated infections.
Principal Advisor
Other advisors: Dr Robert Horvath
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Associate Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Professor Jason Roberts
Completed supervision
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Associate Advisor
Other advisors: Dr Fekade Sime, Professor Jason Roberts
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Professor Jason Roberts
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Professor Kiran Shekar, Professor Jason Roberts
Media
Enquiries
For media enquiries about Dr Hafiz Abdul-Aziz's areas of expertise, story ideas and help finding experts, contact our Media team: