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2018

Journal Article

Is schizophrenia a risk factor for breast cancer?—evidence from genetic data

Byrne, Enda M., Ferreira, Manuel A.R., Xue, Angli, Lindström, Sara, Jiang, Xia, Yang, Jian, Easton, Douglas F., Wray, Naomi R. and Chenevix-Trench, Georgia (2018). Is schizophrenia a risk factor for breast cancer?—evidence from genetic data. Schizophrenia Bulletin, 45 (6), 1251-1256. doi: 10.1093/schbul/sby162

Is schizophrenia a risk factor for breast cancer?—evidence from genetic data

2018

Journal Article

Genotype effects contribute to variation in longitudinal methylome patterns in older people

Zhang, Qian, Marioni, Riccardo E., Robinson, Matthew R., Higham, Jon, Sproul, Duncan, Wray, Naomi R., Deary, Ian J., McRae, Allan F. and Visscher, Peter M. (2018). Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine, 10 (1) 75, 75. doi: 10.1186/s13073-018-0585-7

Genotype effects contribute to variation in longitudinal methylome patterns in older people

2018

Journal Article

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, Simone, Abdalla Diniz, Mateus Jose, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charlesg, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O'Reilly, Paul F., Belangero, Sintia, Bressan, Rodrigo A., Breen, Gerome, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B. ... Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1 (163) 163. doi: 10.1038/s42003-018-0155-y

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

2018

Journal Article

Epigenetic prediction of complex traits and death

McCartney, Daniel L., Hillary, Robert F., Stevenson, Anna J., Ritchie, Stuart J., Walker, Rosie M., Zhang, Qian, Morris, Stewart W., Bermingham, Mairead L., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Gale, Catharine R., Porteous, David J., Haley, Chris S., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J. and Marioni, Riccardo E. (2018). Epigenetic prediction of complex traits and death. Genome Biology, 19 (1) 136, 136. doi: 10.1186/s13059-018-1514-1

Epigenetic prediction of complex traits and death

2018

Journal Article

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

Alvares, Gail A., Dawson, Paul A., Dissanayake, Cheryl, Eapen, Valsamma, Gratten, Jacob, Grove, Rachel, Henders, Anjali, Heussler, Helen, Lawson, Lauren, Masi, Anne, Raymond, Emma, Rose, Felicity, Wallace, Leanne, Wray, Naomi R. and Whitehouse, Andrew J. O. (2018). Study protocol for the Australian autism biobank: an international resource to advance autism discovery research. BMC Pediatrics, 18 (1) 284, 284. doi: 10.1186/s12887-018-1255-z

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

2018

Journal Article

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

Story Jovanova, Olivera, Nedeljkovic, Ivana, Derek, Spieler, Walker, Rosie M., Liu, Chunyu, Luciano, Michelle, Bressler, Jan, Brody, Jennifer, Drake, Amanda J., Evans, Kathryn L., Gondalia, Rahul, Kunze, Sonja, Kuhnel, Brigitte, Lahti, Jari, Lemaitre, Rozenn N., Marioni, Riccardo E., Swenson, Brenton, Himali, Jayandra Jung, Wu, Hongsheng, Li, Yun, McRae, Allan F., Russ, Tom C., Stewart, James, Wang, Zhiying, Zhang, Guosheng, Ladwig, Karl-Heinz, Uitterlinden, Andre G., Guo, Xiuqing, Peters, Annette ... Amin, Najaf (2018). DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies. JAMA Psychiatry, 75 (9), 949-959. doi: 10.1001/jamapsychiatry.2018.1725

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

2018

Journal Article

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, Guiyan, Gratten, Jacob, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R. and Lee, Sang Hong (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports, 8 (1) 10168, 10168. doi: 10.1038/s41598-018-28160-z

Age at first birth in women is genetically associated with increased risk of schizophrenia

2018

Journal Article

Misestimation of heritability and prediction accuracy of male-pattern baldness

Yap, Chloe X., Sirodenko, Julia, Marioni, Riccardo E., Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2018). Misestimation of heritability and prediction accuracy of male-pattern baldness. Nature Communications, 9 (1) 2537, 2537. doi: 10.1038/s41467-018-04807-3

Misestimation of heritability and prediction accuracy of male-pattern baldness

2018

Journal Article

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

van Rheenen, Wouter, Pulit, Sara L., Dekker, Annelot M., Al Khleifat, Ahmad, Brands, William J., Iacoangeli, Alfredo, Kenna, Kevin P., Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L., Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D., Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H. P., van der Spek, Rick A. A., van Doormaal, Perry T. C., van Eijk, Kristel R., van Vugt, Joke, Basak, A. Nazli, Blair, Ian P., Glass, Jonathan D., Hardiman, Orla, Hide, Winston, Landers, John E., Mora, Jesus S., Morrison, Karen E., Newhouse, Stephen ... Veldink, Jan H. (2018). Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis. European Journal of Human Genetics, 26 (10), 1537-1546. doi: 10.1038/s41431-018-0177-4

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

2018

Journal Article

Analysis of shared heritability in common disorders of the brain

Anttila, Verneri, Bulik-Sullivan, Brendan, Finucane, Hilary K., Walters, Raymond K., Bras, Jose, Duncan, Laramie, Escott-Price, Valentina, Falcone, Guido J., Gormley, Padhraig, Malik, Rainer, Patsopoulos, Nikolaos A., Ripke, Stephan, Wei, Zhi, Yu, Dongmei, Lee, Phil H., Turley, Patrick, Grenier-Boley, Benjamin, Chouraki, Vincent, Kamatani, Yoichiro, Berr, Claudine, Letenneur, Luc, Hannequin, Didier, Amouyel, Philippe, Boland, Anne, Deleuze, Jean-Francois, Duron, Emmanuelle, Vardarajan, Badri N., Reitz, Christiane, Goate, Alison M. ... The Brainstorm Consortium (2018). Analysis of shared heritability in common disorders of the brain. Science, 360 (6395) 8757, 1313-+. doi: 10.1126/science.aap8757

Analysis of shared heritability in common disorders of the brain

2018

Journal Article

Common disease is more complex than implied by the core gene omnigenic model

Wray, Naomi R., Wijmenga, Cisca, Sullivan, Patrick F., Yang, Jian and Visscher, Peter M. (2018). Common disease is more complex than implied by the core gene omnigenic model. Cell, 173 (7), 1573-1580. doi: 10.1016/j.cell.2018.05.051

Common disease is more complex than implied by the core gene omnigenic model

2018

Journal Article

Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes

Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A., Pavlides, Jennifer M. Whitehead, Mullins, Niamh, Charney, Alexander W., Ori, Anil P.S., Loohuis, Loes M. Olde, Domenici, Enrico, Di Florio, Arianna, Papiol, Sergi, Kalman, Janos L., Trubetskoy, Vassily, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Akil, Huda, Albani, Diego, Albus, Margot, Alda, Martin, Alexander, Madeline, Alliey-Rodriguez, Ney, Als, Thomas D., Amin, Farooq, Anjorin, Adebayo, Arranz, Maria J., Awasthi, Swapnil ... Kendler, Kenneth S. (2018). Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell, 173 (7), 1705-1715.e16. doi: 10.1016/j.cell.2018.05.046

Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes

2018

Journal Article

Trans-eQTLs identified in whole blood have limited influence on complex disease biology

Yap, Chloe X., Lloyd-Jones, Luke, Holloway, Alexander, Smartt, Peter, Wray, Naomi R., Gratten, Jacob and Powell, Joseph E. (2018). Trans-eQTLs identified in whole blood have limited influence on complex disease biology. European Journal of Human Genetics, 26 (9), 1-8. doi: 10.1038/s41431-018-0174-7

Trans-eQTLs identified in whole blood have limited influence on complex disease biology

2018

Journal Article

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, eQTLGen Consortium, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications, 9 (1) 2282, 2282. doi: 10.1038/s41467-018-04558-1

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

2018

Journal Article

Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood

Ni, Guiyan, Moser, Gerhard, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R. and Lee, S. Hong (2018). Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood. American Journal of Human Genetics, 102 (6), 1185-1194. doi: 10.1016/j.ajhg.2018.03.021

Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood

2018

Journal Article

Analysis of the influence of microRNAs in lithium response in bipolar disorder

Reinbold, Céline S., Forstner, Andreas J., Hecker, Julian, Fullerton, Janice M., Hoffmann, Per, Hou, Liping, Heilbronner, Urs, Degenhardt, Franziska, Adli, Mazda, Akiyama, Kazufumi, Akula, Nirmala, Ardau, Raffaella, Arias, Bárbara, Backlund, Lena, Benabarre, Antonio, Bengesser, Susanne, Bhattacharjee, Abesh K., Biernacka, Joanna M., Birner, Armin, Marie-Claire, Cynthia, Cervantes, Pablo, Chen, Guo-Bo, Chen, Hsi-Chung, Chillotti, Caterina, Clark, Scott R., Colom, Francesc, Cousins, David A., Cruceanu, Cristiana, Czerski, Piotr M. ... Cichon, Sven (2018). Analysis of the influence of microRNAs in lithium response in bipolar disorder. Frontiers in Psychiatry, 9 (MAY) 207, 207. doi: 10.3389/fpsyt.2018.00207

Analysis of the influence of microRNAs in lithium response in bipolar disorder

2018

Journal Article

Correction to: lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling

Zannas, Anthony S., Arloth, Janine, Carrillo-Roa, Tania, Iurato, Stella, Röh, Simone, Ressler, Kerry J., Nemeroff, Charles B., Smith, Alicia K., Bradley, Bekh, Heim, Christine, Menke, Andreas, Lange, Jennifer F., Brückl, Tanja, Ising, Marcus, Wray, Naomi R., Erhardt, Angelika, Binder, Elisabeth B. and Mehta, Divya (2018). Correction to: lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology, 19 (1) 61, 61-61. doi: 10.1186/s13059-018-1441-1

Correction to: lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling

2018

Journal Article

GWAS on family history of Alzheimer's disease

Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer's disease. Translational Psychiatry, 8 (1) 99, 99. doi: 10.1038/s41398-018-0150-6

GWAS on family history of Alzheimer's disease

2018

Journal Article

Comparison of genotypic and phenotypic correlations: Cheverud's conjecture in humans

Sodini, Sebastian M., Kemper, Kathryn E., Wray, Naomi R. and Trzaskowski, Maciej (2018). Comparison of genotypic and phenotypic correlations: Cheverud's conjecture in humans. Genetics, 209 (3), 941-948. doi: 10.1534/genetics.117.300630

Comparison of genotypic and phenotypic correlations: Cheverud's conjecture in humans

2018

Journal Article

Familiality of psychiatric disorders and risk of postpartum psychiatric episodes: a population-based cohort study

Bauer, Anna E., Maegbaek, Merete L., Liu, Xiaoqin, Wray, Naomi R., Sullivan, Patrick F., Miller, William C., Meltzer-Brody, Samantha and Munk-Olsen, Trine (2018). Familiality of psychiatric disorders and risk of postpartum psychiatric episodes: a population-based cohort study. The American Journal of Psychiatry, 175 (8), appiajp201817111184-791. doi: 10.1176/appi.ajp.2018.17111184

Familiality of psychiatric disorders and risk of postpartum psychiatric episodes: a population-based cohort study