Professor Jeffrey Lipman
Professor

Jeffrey Lipman

Email: 
Phone: 
+61 7 334 65015
Phone: 
+61 7 3646 1847

Background

Prof Lipman is Executive Director of the Burns Trauma & Critical Care Research Centre; Professor of Anesthesiology & Critical Care, The University of Queensland and until recently (for 23 years) was Director of Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital; He holds Honorary Professorial appointments at Chinese University of Hong Kong, Unversity of Witwatersrand (South Africa) and Qeensland University of Technology.

He has qualifications in anesthesia and intensive care and has set up and been in charge of a number of Intensive Care and Trauma Units in South Africa before coming to Australia in 1997. he currently manages a large multidisciplinary research team with an output of over 120 peer-reviewed articles per annum. He has supervised dozens of PhD students to completion and is currently supervising 6 PhD, 1 MPhil and 1 MBBS/Hons students. Prof Lipman has been instrumental in developing the anaesthesiology and critical care component of a graduate medical program for Queensland and continues to lecture to medical and postgraduate students.

Prof Lipman is the author of over 550 peer reviewed publications, 30 book chapters and has been invited to deliver over 120 lectures at national and international conferences in many countries across the world. His research interests include all aspects of infection management in intensive care and he has a special interest in the pharmacokinetics of antibiotic dosage, an area in which he received his MD in 2006. His research into antibiotic usage in acute situations has received international recognition and he is regarded as an expert in the field. As such, he and his research team have conducted and presently conduct a number of clinical trials in Australia, New Zealand, Hong Kong, Europe and the UK.

Prof Lipman is an Editorial Board member for 10 International Journals, is Section Editor on four Antibiotic related Journals, reviews for 23 journals and is an external reviewer for NHMRC project grants (Local) as well as equivalent for a number overseas countries.

He is Chief Investigator on a 7000 patient International Randomised Controlled Trial comparing bolus dosing versus continuous infusions of meropenem and piperacillin-tazobactam

Availability

Professor Jeffrey Lipman is:
Not available for supervision
Media expert

Fields of research

Anaesthesiology Biomedical and Clinical Sciences Clinical pharmacology and therapeutics Clinical sciences Infectious diseases Intensive care Pharmacology and pharmaceutical sciences

Research interests

  • Antibiotic dosing in critically ill patients

    Severe sepsis is defined as failure of one or more organ systems, most commonly cardiovascular (including shock), respiratory and renal failure, caused by infection. Bacteria, either alone or in combination with other pathogens, are the most common cause of severe sepsis, and Gram-positive and Gram-negative organism account for up to 87% of culture positive episodes. Severe sepsis is a major cause of mortality worldwide. The ANZICS CTG reported that the Australian and New Zealand adult annual incidence of severe sepsis is 77 cases per 100,000,4 which is equivalent to over 17,000 patient episodes per year at an estimated cost per episode of AUD 42,300. Similar population incidence rates have been reported elsewhere. Importantly, 11.8% of all admissions to Australian and New Zealand ICUs are associated with severe sepsis and in-hospital mortality is 37.5%. In patients with septic shock, mortality approaches 60%. The burden of death is almost four times the annual national road toll. The death rate also exceeds other diseases that impact significantly on the Australian community, such as breast and colorectal cancer. In short, severe sepsis is a major public health concern in Australia and improved therapies are needed urgently. My research group is conducting national and international clinical trials investigating the effect of various dosing regimes on health outcomes in critically ill patients.

Research impacts

My research has been instrumental in changing antibiotic prescribing habits worldwide for critically ill patients, first with aminoglycosides (I did the first and still largest clinical trial to show single daily dosing to be effective) and more recently with beta-lactam antibiotics. Due to critically ill patients having altered pharmacokinetics, using standard antibiotic dosing for these patients is fraught with problems. This has led to the use of Therapeutic Drug Monitoring (TDM) for beta-lactams.

TDM of aminoglycosides and glycopeptides is performed to decrease side-effects of these drugs. Beta-lactams have a large therapeutic ratio and hence measurement of them is infrequent. I helped set up routine TDM of beta-lactam antibiotics at RBWH. I have changed how we dose patients particularly in ICU but also within the wards of RBWH. By means of TDM we have shown we need dose adjustments in 74% of patients to which we administer β-lactam antibiotics in the ICU (Roberts JA et al. Int J Antimicrob Agents 2010;36:332-39). Although scarcely performed world-wide, TDM of beta-lactams is now becoming more commonly performed. We are currently collating data from 5 International centres that also use TDM in an attempt to show outcome benefits of TDM and are starting to publish accordingly (Wong G et al. An international, multi-centre survey of beta-lactam antibiotics TDM practice in intensive care units. J Antimicrob Chemother 2014;69: 1416–1423).

Search Professor Jeffrey Lipman’s works on UQ eSpace

727 works between 1981 and 2025
All (727) Journal Article (684) Book Chapter (21) Conference Publication (16) Book (3) Other Outputs (3)

41 - 60 of 727 works

2023

Journal Article

Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes

Joynt, Gavin Matthew, Ling, Lowell, Wong, Wai Tat and Lipman, Jeffrey (2023). Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes. Expert Review of Clinical Pharmacology, 16 (8), 703-714. doi: 10.1080/17512433.2023.2194629

Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes

2023

Journal Article

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

2023

Journal Article

A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study

Roberts, Jason A., Sime, Fekade, Lipman, Jeffrey, Hernández-Mitre, Maria Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2023). A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study. Critical Care and Resuscitation, 25 (1), 1-5. doi: 10.1016/j.ccrj.2023.04.002

A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study

2023

Journal Article

Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman and Dulhunty, Joel M. (2023). Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]. Critical Care and Resuscitation, 25 (1), 60-60. doi: 10.1016/j.ccrj.2023.04.012

Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]

2023

Book Chapter

Antimicrobial agents with primary activity against gram-negative bacteria

Niederman, Michael S., Koulenti, Despoina and Lipman, Jeffrey (2023). Antimicrobial agents with primary activity against gram-negative bacteria. Textbook of critical care. (pp. 853.e10-871.e10) edited by Jean-Louis Vincent, Frederick A. Moore, Rinaldo Bellomo and John J. Marini. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-323-75929-8.00116-7

Antimicrobial agents with primary activity against gram-negative bacteria

2023

Journal Article

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

Tabah, Alexis, Buetti, Niccolò, Staiquly, Quentin, Ruckly, Stéphane, Akova, Murat, Aslan, Abdullah Tarik, Leone, Marc, Conway Morris, Andrew, Bassetti, Matteo, Arvaniti, Kostoula, Lipman, Jeffrey, Ferrer, Ricard, Qiu, Haibo, Paiva, José-Artur, Povoa, Pedro, De Bus, Liesbet, De Waele, Jan, Zand, Farid, Gurjar, Mohan, Alsisi, Adel, Abidi, Khalid, Bracht, Hendrik, Hayashi, Yoshiro, Jeon, Kyeongman, Elhadi, Muhammed, Barbier, François, Timsit, Jean-François, Tabah, Alexis, Pollock, Hamish ... Finnis, Mackenzie (2023). Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study. Intensive Care Medicine, 49 (2), 178-190. doi: 10.1007/s00134-022-06944-2

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

2023

Journal Article

Advancing precision-based antimicrobial dosing in critically ill patients

Cotta, Menino O., Lipman, Jeffrey and De Waele, Jan (2023). Advancing precision-based antimicrobial dosing in critically ill patients. Intensive Care Medicine, 49 (3), 324-326. doi: 10.1007/s00134-022-06969-7

Advancing precision-based antimicrobial dosing in critically ill patients

2022

Journal Article

Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients

Ling, Lowell, Mui, Oliver Oi Yat, Laupland, Kevin B., Lefrant, Jean-Yves, Roberts, Jason A., Gopalan, Pragasan Dean, Lipman, Jeffrey, Joynt, Gavin M., Stelfox, Tom, Niven, Daniel, Paramalingam, Rameiya, Vonderhaar, Derek, Freebairn, Ross, Ling, Lowell, Leung, Patricia, Gopalan, Dean, Lefrant, Jean Yves, Lloret, Sophie, Elotmani, Loubna, Fourie, Cheryl, Saba, Renee, Carlisle, Dougal and Edwards, Felicity (2022). Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients. Journal of Intensive Care, 10 (1) 44, 1-10. doi: 10.1186/s40560-022-00633-4

Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients

2022

Journal Article

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

De Pascale, Gennaro, Antonelli, Massimo, Deschepper, Mieke, Arvaniti, Kostoula, Blot, Koen, Brown, Ben Creagh, de Lange, Dylan, De Waele, Jan, Dikmen, Yalim, Dimopoulos, George, Eckmann, Christian, Francois, Guy, Girardis, Massimo, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovetsky, Fernando, Maseda, Emilio, Montravers, Philippe, Mikstacki, Adam, Paiva, José-Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Vogelaers, Dirk, Blot, Stijn, Lamrous, Amin, Lipovestky, Fernando, Rezende-Neto, Joao ... Davis, Noelle (2022). Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis. Intensive Care Medicine, 48 (11), 1593-1606. doi: 10.1007/s00134-022-06883-y

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

2022

Journal Article

A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

Alonso, Julio M., Lipman, Jeffrey and Shekar, Kiran (2022). A novel barrier device and method for protection against airborne pathogens during endotracheal intubation. European Journal of Anaesthesiology, 39 (11), 900-903. doi: 10.1097/EJA.0000000000001731

A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

2022

Journal Article

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

Buetti, Niccolò, Tabah, Alexis, Loiodice, Ambre, Ruckly, Stéphane, Aslan, Abdullah Tarik, Montrucchio, Giorgia, Cortegiani, Andrea, Saltoglu, Nese, Kayaaslan, Bircan, Aksoy, Firdevs, Murat, Akova, Akdoğan, Özlem, Saracoglu, Kemal Tolga, Erdogan, Cem, Leone, Marc, Ferrer, Ricard, Paiva, José-Artur, Hayashi, Yoshiro, Ramanan, Mahesh, Conway Morris, Andrew, Barbier, François, Timsit, Jean-François, Lipman, Jeffrey, Litton, Edward, Palermo, Anna Maria, Yap, Timothy, Eroglu, Ege, Hosokawa, Koji, Yoshida, Hideki ... Hamid, Hytham K. S. (2022). Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study. Critical Care, 26 (1) 319, 1-12. doi: 10.1186/s13054-022-04166-y

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

2022

Journal Article

Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients

Truong, Anh Quan, Dao, Xuan Co, Vu, Dinh Hoa, Nguyen, Hoang Anh, Do, Thi Hong Gam, Tran, Nhan Thang, Tran, Nhat Minh, Vu, Ngan Binh, Pham, Hong Nhung, Bui, Van Cuong, Trinh, The Anh, Dang, Quoc Tuan, Nguyen, Gia Binh, Lipman, Jeffrey, Cotta, Menino O. and Roberts, Jason A. (2022). Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (11) e0032122, 1-11. doi: 10.1128/aac.00321-22

Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients

2022

Journal Article

Laryngeal injury following endotracheal intubation: have you considered reflux?

Menon, Rahul, Vasani, Sarju S, Widdicombe, Neil J. and Lipman, Jeffrey (2022). Laryngeal injury following endotracheal intubation: have you considered reflux?. Anaesthesia and Intensive Care, 51 (1), 14-19. doi: 10.1177/0310057x221102472

Laryngeal injury following endotracheal intubation: have you considered reflux?

2022

Journal Article

Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs

Jager, Nynke G. L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2022). Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs. Clinical Microbiology and Infection, 28 (9) 1211, 1211-1224. doi: 10.1016/j.cmi.2022.03.041

Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs

2022

Journal Article

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates. Journal of Antimicrobial Chemotherapy, 77 (11), 3026-3034. doi: 10.1093/jac/dkac273

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates

2022

Journal Article

Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study. Antimicrobial Agents and Chemotherapy, 66 (8) e0014222, 1-12. doi: 10.1128/aac.00142-22

Plasma and cerebrospinal fluid population pharmacokinetics of meropenem in neurocritical care patients: a prospective two-center study

2022

Journal Article

Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients

Ryan, Rochelle L., Jackson, Dwane, Hopkins, George, Eley, Victoria, Christensen, Rebecca, Van Zundert, Andre A. J., Wallis, Steven C., Lipman, Jeffrey, Parker, Suzanne L. and Roberts, Jason A. (2022). Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients. Antimicrobial Agents and Chemotherapy, 66 (7), e0041922. doi: 10.1128/aac.00419-22

Plasma and interstitial fluid pharmacokinetics of prophylactic cefazolin in elective bariatric surgery patients

2022

Journal Article

Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2022). Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?. Journal of Antimicrobial Chemotherapy, 77 (8), 2227-2237. doi: 10.1093/jac/dkac168

Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?

2022

Journal Article

A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit

Wiebe, Jordan, Lipman, Jeffrey and Reade, Michael C. (2022). A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit. Critical Care and Resuscitation, 24 (2), 183-187. doi: 10.51893/2022.2.OA8

A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit

2022

Journal Article

Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study

Tsai, Danny, Chiong, Fabian, Secombe, Paul, Hnin, Khin Moe, Stewart, Penny, Goud, Rajendra, Woodman, Richard, Lipman, Jeffrey, Roberts, Jason and Hewagama, Saliya (2022). Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study. Internal Medicine Journal, 52 (6), 1048-1056. doi: 10.1111/imj.15171

Epidemiology and microbiology of severe community‐acquired pneumonia in Central Australia: a retrospective study

Current funding

  • 2021 - 2026
    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
    NHMRC Centres of Research Excellence
    Open grant
  • 2015 - 2025
    TxA levels in the PATCH-Trauma trial
    Intensive Care Foundation
    Open grant
  • 2014 - 2025
    Research donations in support of the Burns Trauma and Critical Care Research Centre
    Royal Brisbane and Women's Hospital Foundation
    Open grant

Past funding

  • 2023
    Assessing the level of adherence to the new developed work-based oral care bundles for critical care patients to ensure service quality
    Australian Dental Research Fund Inc
    Open grant
  • 2022 - 2023
    Assessing the level of adherence to current work-based guidelines in oral care for critical care patients to improve service quality
    Metro North Hospital and Health Service
    Open grant
  • 2022 - 2023
    Investigating Metabolic Acidosis in Gastroenterology Induced by Colonoscopy preparation and Sodium glucose transporter 2 inhibitors: The MAGICS Study (MSH HHS Project Grant administered by MSH HHS)
    Metro South Hospital and Health Service
    Open grant
  • 2021 - 2023
    Continuous vs intermittent infusion of beta-lactam antibacterial drugs: impact on resistance and outcomes in sepsis - PMWP 170
    United States Food and Drug Administration
    Open grant
  • 2021 - 2022
    Developing evidence-based antibiotic dosing guidelines during extracorporeal therapies using advanced pharmacometric methods... (RBWH grant administered by UQ)
    Metro North Hospital and Health Service
    Open grant
  • 2020 - 2021
    The effect of extracorporeal membrane oxygenation (ECMO) on the effectiveness of Coronavirus Disease 2019 (COVID-19) pharmacotherapy - ex vivo characterisation and quantification [...]
    Metro North Hospital and Health Service
    Open grant
  • 2020
    Rapid detection of resistance genes from Gram-negative bacteria isolated from blood in ICU-admitted patients
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2019 - 2021
    Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients (Led by MNHHS)
    Metro North Hospital and Health Service
    Open grant
  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2024
    Novel dosing regimens to maximise antibiotic effectiveness for treatment of pneumonia in the intensive care unit
    NHMRC Project Grant
    Open grant
  • 2018
    Effect of albumin resuscitation on drug pharmacokinetics in low protein and LPS challenged sheep
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2018
    Ion Mobility Separation of Challenging Clinical Samples
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    Nuclear medicine suite for animals
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    Pharmacokinetic-pharmacodynamic substudy of patients with severe sepsis randomised to receive beta-lactam antibiotics by either intermittent or continuous infusion.
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2018
    Does routine antibiotic administration in overweight women having elective caesarean section achieve therapeutic levels?
    Metro North Hospital and Health Service
    Open grant
  • 2017
    Implementing microsampling into clinical pharmacokinetic research studies - it only takes a drop of blood!
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2017 - 2018
    Pharmacokinetic-pharmacodynamic substudy of patients with severe sepsis randomised to receive beta-lactam antibiotics by either intermittent or continuous infusion
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016 - 2018
    Using a drop of blood to personalise antibiotic dosing in children and prevent antibiotic resistance
    Ian Potter Foundation
    Open grant
  • 2016 - 2019
    A biomarker for Sepsis to thwart antibiotic overuse in the Intensive Care Unit
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016
    Pharmacokinetic/Pharmacodynamic (PK/PD) analysis of antimicrobials in renal replacement therapy (RRT) and septic shock
    University Hospital of Nîmes
    Open grant
  • 2015 - 2021
    Centre for REdefining antibiotic use to reDUce resistanCE and prolong the lives of antibiotics (REDUCE)
    NHMRC Centres of Research Excellence
    Open grant
  • 2015 - 2017
    SoM Leaders Research Support for Head Academic Discipline of Anaesthesiology and Critical Care
    Mayne Bequest Fund
    Open grant
  • 2015
    Pharmacokinetic Australasian Collaborative
    Intensive Care Foundation
    Open grant
  • 2015 - 2016
    A biomarker for sepsis to thwart antibiotic overuse in the intensive care unit
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015
    Addressing an unmet need by establishing a state-of-the-art translational model at UQ: The hollow fibre in vitro infection model
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2019
    CAMERA 2: Combination antibiotic treatment for methicillin resistant Staphylococcus aureus bacteraemia - a randomised controlled trial (NHMRC Project Grant administered by Menzies)
    Menzies School of Health Research
    Open grant
  • 2015
    Incidence, risk factors, consequences and treatment of ventilated patients with nosocomial infection with pandrug resistant organisms in hospitals in Asia
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2015
    Pilot randomised controlled trial of meropenem versus piperacillin-tazobactam for the definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp, ...
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2015
    Interventional multi-centre prospective epidemiological study of ventilator-associated pneumonia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2015
    A Phase II randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients
    Auckland District Health Board Charitable Trust
    Open grant
  • 2014 - 2017
    Innovative dosing approaches to maximise bacterial killing and prevent resistance in septic critically ill patients
    NHMRC Project Grant
    Open grant
  • 2014
    Strenghtening the School of Medicine's position as a central coordinator of global pharmacokenetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2014
    Randomised controlled trial of beta-lactam continuous infusion compared with intermittent dosing in critically ill patients
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2016
    Robust antibiotic dosing for critically ill patients receiving renal replacement therapy
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    A phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients (Special Purpose Grant BTCCRC)
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2012 - 2017
    A Phase IIb Randomised Controlled Trial of Continuous Beta-Lactam Infusion Compared With Intermittent Beta-Lactam Dosing in Critically Ill Patients With Severe Sepsis
    Baxter Healthcare Pty Ltd
    Open grant
  • 2012 - 2015
    A phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis
    NHMRC Project Grant
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2014
    Identifying a cost-effective approach to MRSA control in Australia (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2012 - 2015
    Pilot Study of pharmacokinetic and pharmacodynamic assessment of monotherapy versus combination therapy for the management of gram negative bacteraemia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012 - 2015
    Prevention of Ventilator Associated Pneumonia by Inhaled Heparin
    Australian and New Zealand Intensive Care Foundation
    Open grant
  • 2012
    Tandem fluorescent and phase-contrast imaging of live cells in real time for application to cancer cell biology, developmental biology, respiratory biology, wound healing investigation and cellular to
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2013
    UQ/UWA joint project on Severe Sepsis
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2011 - 2013
    Microdialysis to monitor fluid shifts and predict organ failure in the systemic inflammatory response syndrome
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2011 - 2012
    DALI: Defining antibiotic levels in intensive care unit patients
    European Society of Intensive Care Medicine
    Open grant
  • 2010 - 2012
    Examining Sepsis in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2015
    Microcirculation in shocked patients
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2016
    Tamsulosin for the treatment of Distal Ureteric Calculi: A double-blinded, placebo-controlled, randomised, multi-centre trial
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Pilot RCT of continuous beta-lactam infusion compared with intermittent dosing in critically ill patients
    Australian and New Zealand Intensive Care Foundation
    Open grant
  • 2010
    Improving outcomes post major trauma
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2012
    Pharmacokinetics in continuous venovenous haemodiafiltration (CVVHDF) - using plasma and tissue antibiotic concentrations to optimise dosing of beta-lactam antibodies
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2012
    Mayne Bequest Fund Research Support Award: Sepsis and Intensive Care
    Mayne Bequest Fund
    Open grant
  • 2009 - 2011
    Myocardial function in burns: A Prospective and observational study
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2014
    Assessment of the Microcirculation in Shocked Critically Unwell Patients during the first 24 hours of resuscitation
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2011
    Pharmacokinetics of Cephalothin, Vancomycin and Gentamicin Used for Antimicrobial Prophylaxis during elective abdominal aortic aneurysm surgery
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2009 - 2011
    Glomerular Hyperfiltration in at risk patients on Admission to the Intensive Care Unit (GHAU) Study
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009
    Improving outcomes post burn injury
    UQ School/Centre Co-Funding
    Open grant
  • 2009 - 2014
    Inhaled Prophylactic-Heparin In Ventilator Associated Pneumonia Prevention Trial (IPHAPP)
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2011
    The Sepsis Registry: A prospective database to characterise and facilitate improved outcome for admitted patients with community-acquired infection
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2008 - 2010
    Antibiotic dosing in the at risk critically ill patient
    NHMRC Project Grant
    Open grant
  • 2008
    Imaging of the microcirculation using the Microscan (orthogonal polarization spectral imaging) and providing improved quality of drug analysis for PK studies in critically ill patients
    NHMRC Equipment Grant
    Open grant
  • 2008
    Improved quantification of spatial and temporal changes in plasma and tissue drug levels and tissue pathology
    NHMRC Equipment Grant
    Open grant
  • 2007
    Multi-drug resistant Acinetobacter: an emerging nosocomial pathogen
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2006 - 2007
    Microdialysis in antibiotic dosing, pain management and neurosurgical outcome
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2006
    NHMRC_Infrastructure Item_Metabolic Exercise System, MetaMax Portable CPX
    Open grant
  • 2006 - 2007
    Pharmacokinetic Modelling of Various B-lactam Antibiotics in Critically-ill Patients using Microdialysis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2005
    Advanced auditory displays for patient monitoring in anesthesia and intensive care
    University of Queensland Research Development Grants Scheme
    Open grant
  • 2005 - 2007
    Management of burn injury: Fluid dynamics and antibiotic pharmacokinetics
    NHMRC Project Grant
    Open grant
  • 2005
    NHMRC Equipment Grant : Estimation of drugs, peptides and metabolites using HPLC-Mass-spectrometry-microdialysis
    NHMRC Equipment Grant
    Open grant
  • 2005
    Optimal Antibiotic Dosing in Burns: Fluid Dynamics and Drug Tissue Pharmacokinetics
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2005 - 2006
    Start-up Grant
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2005 - 2008
    Study of Risk Assessment To reduce complications In patients Following noncardiac surgerY (STRATIFY)
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    Supplementary funding to advance development
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2004 - 2015
    Burns, Trauma, Critical Care Research Centre
    Royal Women's Hospital Research & Development Foundation
    Open grant
  • 2004 - 2009
    Burns, Trauma and Critical Care Research Centre
    Mayne Bequest Fund
    Open grant

Availability

Professor Jeffrey Lipman is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Professor Jeffrey Lipman directly for media enquiries about:

  • Antibiotics
  • Intensive care
  • pharmacokinetics

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