Professor Linda Lua
Professor

Linda Lua

Email: 

Availability

Professor Linda Lua is:
Not available for supervision

Fields of research

Biological control Bioprocessing, bioproduction and bioproducts Environmental biotechnology Industrial biotechnology

Qualifications

  • Bachelor (Honours) of Applied Science, The University of Queensland
  • Doctor of Philosophy of Bioengineering, The University of Queensland

Research interests

  • Protein Technologies

  • Bioengineering virus-like particle as vaccines

Search Professor Linda Lua’s works on UQ eSpace

85 works between 1999 and 2024
All (85) Journal Article (70) Book Chapter (3) Conference Publication (9) Other Outputs (3)

21 - 40 of 85 works

2017

Journal Article

Evaluation of three adjuvants with respect to both adverse effects and the efficacy of antibody production to the Bm86 protein

Petermann, Julie, Bonnefond, Romain, Mermoud, Isabelle, Rantoen, Dewi, Meynard, Laure, Munro, Christopher, Lua, Linda H. L. and Hue, Thomas (2017). Evaluation of three adjuvants with respect to both adverse effects and the efficacy of antibody production to the Bm86 protein. Experimental and Applied Acarology, 72 (3), 303-315. doi: 10.1007/s10493-017-0156-4

Evaluation of three adjuvants with respect to both adverse effects and the efficacy of antibody production to the Bm86 protein

2017

Journal Article

Platform technologies for modern vaccine manufacturing

Charlton Hume, Hayley K. and Lua, Linda H. L. (2017). Platform technologies for modern vaccine manufacturing. Vaccine, 35 (35), 4480-4485. doi: 10.1016/j.vaccine.2017.02.069

Platform technologies for modern vaccine manufacturing

2017

Journal Article

Small-molecule inhibitors of the SOX18 transcription factor

Fontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias (2017). Small-molecule inhibitors of the SOX18 transcription factor. Chemistry Chemical Biology, 24 (3), 346-359. doi: 10.1016/j.chembiol.2017.01.003

Small-molecule inhibitors of the SOX18 transcription factor

2017

Journal Article

Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?

Razaghi, Ali, Tan, Emilyn, Lua, Linda H. L., Owens, Leigh, Karthikeyan, O. P. and Heimann, Kirsten (2017). Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?. Biologicals, 45, 52-60. doi: 10.1016/j.biologicals.2016.09.015

Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?

2016

Journal Article

Modular virus-like particles for sublingual vaccination against group A streptococcus

Seth, Arjun, Kong, Il Gyu, Lee, Su-Hyun, Yang, Jin-Young, Lee, Yong-Soo, Kim, Yeji, Wibowo, Nani, Middelberg, Anton P.J., Lua, Linda H.L. and Kweon, Mi-Na (2016). Modular virus-like particles for sublingual vaccination against group A streptococcus. Vaccine, 34 (51), 6472-6480. doi: 10.1016/j.vaccine.2016.11.008

Modular virus-like particles for sublingual vaccination against group A streptococcus

2016

Journal Article

Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination

Waneesorn, Jarurin, Wibowo, Nani, Bingham, John, Middelberg, Anton P. J. and Lua, Linda H.L. (2016). Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination. Vaccine, 36 (22), 3064-3071. doi: 10.1016/j.vaccine.2016.11.058

Structural-based designed modular capsomere comprising HA1 for low-cost poultry influenza vaccination

2016

Journal Article

Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen

Tekewe, Alemu, Fan, Yuanyuan, Tan, Emilyn, Middelberg, Anton P. J. and Lua, Linda H. L. (2016). Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen. Biotechnology and Bioengineering, 114 (2), 397-406. doi: 10.1002/bit.26068

Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen

2016

Journal Article

Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle

Tekewe, Alemu, Connors, Natalie K., Middelberg, Anton P. J. and Lua, Linda H. L. (2016). Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle. Protein Science, 25 (8), 1507-1516. doi: 10.1002/pro.2953

Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle

2016

Conference Publication

Sublingual vaccination with self-adjuvanting virus-like particles against Group A streptococcus elicit protective immunity in systemic and mucosal sites: implication for allergen-specific immunotherapy

Kong, I, Seth, A., Yang, J-Y, Lee, S-H, Lee, Y-S, Kim, Y., Middelberg, A., Wibowo, N., Lua, L. and Kweon, M-N (2016). Sublingual vaccination with self-adjuvanting virus-like particles against Group A streptococcus elicit protective immunity in systemic and mucosal sites: implication for allergen-specific immunotherapy. Meeting of the European Academy of Allergy and Clinical Immunology, Vienna, Austria, Jun 11-15, 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Sublingual vaccination with self-adjuvanting virus-like particles against Group A streptococcus elicit protective immunity in systemic and mucosal sites: implication for allergen-specific immunotherapy

2015

Journal Article

Vaccine

Wibowo, Nani, Lua, Linda Hwee-Lin, Jungbauer, Alois and Ma, Guanghui (2015). Vaccine. Vaccine Engineering, 33 (44), 5889-5889. doi: 10.1016/j.vaccine.2015.10.002

Vaccine

2015

Journal Article

Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza

Wibowo, Nani, Wu, Yang, Fan, Yuanyuan, Meers, Joanne, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza. Vaccine, 33 (44), 5960-5965. doi: 10.1016/j.vaccine.2015.08.100

Non-chromatographic preparation of a bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza

2015

Journal Article

Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle

Lua, Linda H.L., Fan, Yuanyuan, Chang, Cindy, Connors, Natalie K. and Middelberg, Anton P.J. (2015). Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle. Vaccine, 33 (44), 5937-5944. doi: 10.1016/j.vaccine.2015.09.017

Synthetic biology design to display an 18 kDa rotavirus large antigen on a modular virus-like particle

2015

Journal Article

Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes

Abidin, R.S., Lua, L.H.L., Middelberg, A.P.J. and Sainsbury, F. (2015). Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes. Protein Science, 24 (11), 1820-1828. doi: 10.1002/pro.2775

Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes

2015

Journal Article

Biomolecular engineering of virus-like particles aided by computational chemistry methods

Zhang, Lin, Lua, Linda H. L., Middelberg, Anton P. J., Sun, Yan and Connors, Natalie K. (2015). Biomolecular engineering of virus-like particles aided by computational chemistry methods. Chemical Society Reviews, 44 (23), 8608-8618. doi: 10.1039/c5cs00526d

Biomolecular engineering of virus-like particles aided by computational chemistry methods

2015

Journal Article

A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates

Tekewe, Alemu, Connors, Natalie K., Sainsbury, Frank, Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates. Biochemical Engineering Journal, 100, 50-58. doi: 10.1016/j.bej.2015.04.004

A rapid and simple screening method to identify conditions for enhanced stability of modular vaccine candidates

2015

Journal Article

Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner

Seth, Arjun, Ritchie, Fiona K., Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2015). Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner. PLoS One, 10 (3) 0117203, e0117203-e0117203. doi: 10.1371/journal.pone.0117203

Non-Carrier Nanoparticles Adjuvant ModularProtein Vaccine in a Particle-Dependent Manner

2015

Journal Article

Development of picornavirus-like particle vaccines

Somasundaram, Balaji and Lua, Linda H. L. (2015). Development of picornavirus-like particle vaccines. Pharmaceutical Bioprocessing, 3 (1), 45-49. doi: 10.4155/pbp.14.39

Development of picornavirus-like particle vaccines

2015

Journal Article

Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells

Somasundaram, Balaji, Chang, Cindy, Fan, Yuan Y., Lim, Pei-Yin, Cardosa, Jane and Lua, Linda (2015). Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells. Methods, 95, 38-45. doi: 10.1016/j.ymeth.2015.09.023

Characterizing Enterovirus 71 and Coxsackievirus A16 Virus-like Particles Production in Insect Cells

2014

Journal Article

The economics of virus-like particle and capsomere vaccines

Chuan, Yap P., Wibowo, Nani, Lua, Linda H. L. and Middelberg, Anton P. J. (2014). The economics of virus-like particle and capsomere vaccines. Biochemical Engineering Journal, 90, 255-263. doi: 10.1016/j.bej.2014.06.005

The economics of virus-like particle and capsomere vaccines

2014

Journal Article

Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations

Zhang, Lin, Tang, Ronghong, Bai, Shu, Connors, Natalie K., Lua, Linda H. L., Chuan, Yap P., Middelberg, Anton P. J. and Sun, Yan (2014). Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations. PLoS One, 9 (9) e107313, e107313.1-e107313.12. doi: 10.1371/journal.pone.0107313

Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations

Past funding

  • 2021 - 2022
    Scale-down biomanufacturing capabilities to translate health discoveries into clinical applications
    IPF Healthy - Medical Research
    Open grant
  • 2020 - 2023
    Enhancing biopharmaceuticals: a disruptive bioseparation resin technology (ARC Discovery Project administered by Griffith University)
    Griffith University
    Open grant
  • 2019
    Advanced biomanufacturing with versatile yeast expression platform
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2019
    Cyto-Mine to accelerate Cell Line Development for Vaccines and Biopharmaceuticals
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Continuous chromatography system for advanced bioprocessing
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Enabling research and development of next generation mammalian cell-based products
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2017 - 2023
    ARC Training Centre for Biopharmaceutical Innovation
    ARC Industrial Transformation Training Centres
    Open grant
  • 2016 - 2019
    Engineering a nanovaccine for cost-effective influenza poultry vaccination
    ARC Discovery Projects
    Open grant
  • 2016
    Rapid analysis of protein stability and aggregation
    UQ Major Research Facility Fund
    Open grant
  • 2014 - 2016
    Human enterovirus-like particle vaccine development
    Sentinext Therapeutics
    Open grant
  • 2014
    Coxsackievirus-A16 VLP Vaccine Development
    UniQuest Pty Ltd
    Open grant
  • 2012 - 2014
    Expression of EV71 VLPs in insect cells
    UniQuest Pty Ltd
    Open grant
  • 2010 - 2013
    Vaccine Now - Beating Infectious Disease with Rapid Response Technology
    Queensland Government Smart State National and International Research Alliances Program
    Open grant
  • 2007 - 2009
    Terahertz Spectroscopy of Mass-Manufactured Viral Vaccines
    ARC Discovery Projects
    Open grant
  • 2006 - 2007
    Simplified Process Methods for Mass Vaccine Manufacture
    NHMRC Potential Avian Influenza - induced pandemic
    Open grant
  • 2005 - 2008
    Bio-based Functional Materials from Engineered Self-Assembling Peptides (BASE)
    Department of Innovation, Industry, Science and Research - ISL French-Australian Science and Technology Program
    Open grant

Availability

Professor Linda Lua is:
Not available for supervision

Supervision history

Current supervision

  • Doctor Philosophy

    Development of continuous downstream processing platform tools for implementation at a biologics contract development and manufacturing organization

    Principal Advisor

  • Doctor Philosophy

    Broad Spectrum Medical Countermeasure development for Organophosphate Compounds

    Principal Advisor

    Other advisors: Professor David Owen

  • Doctor Philosophy

    Development of commercially viable cyclic peptide production for the protection of the Great Barrier Reef

    Principal Advisor

    Other advisors: Dr Conan Wang, Professor David Craik, Dr Thomas Durek

Completed supervision

Enquiries

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