Emerita Professor Jenny Martin
Emerita Professor

Jenny Martin

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Background

Jenny Martin trained as a pharmacist at the Victorian College of Pharmacy (VCP), where she was awarded the Gold Medal for top student over the BPharm course. After completing an MPharm in computational chemistry at the College, Jenny moved to Oxford University for a PhD by research in protein crystallography and drug design. Her DPhil was supported by a prestigious 1851 Science Research Scholarship and several other competitive scholarships. Jenny then undertook two years of postdoctoral research at Rockefeller University in New York, before returning to Australia in 1993 to establish the first protein crystallography laboratory in Queensland. Since then, she has held ARC QEII, ARC Professorial and NHMRC Fellowships and is currently an ARC Australian Laureate Fellow at the Institute for Molecular Bioscience, University of Queensland. Jenny is the recipient of many honours including the ASBMB Roche Medal, the Queensland Smart Women Smart State Research Scientist award, and the Women in Biotech Outstanding Outstanding Biotechnology Achievement Award.

Availability

Emerita Professor Jenny Martin is:
Not available for supervision
Media expert

Qualifications

  • Bachelor of Pharmacy, Victoria University
  • Masters (Coursework), Victoria University
  • Doctor of Philosophy, University of Oxford

Research impacts

Prof Martin has contributed to knowledge through more than 110 crystal structures deposited into the protein data bank. She has also contributed to the development of patented antidiabetics, HIV-protease inhibitors, and patents leading to the development of conotoxin drugs that progressed to clinical trials. In addition, through a consultancy with PanBIO (now Inverness Medical Innovations) Prof Martin contributed to a patented diagnostic for herpes simplex virus. She has also held ARC Linkage projects with biotech companies Alchemia, Hexima and Biota leading to fundamental and applied research outcomes. As a leader in her field, Jenny has chaired the National Committee for Crystallography of the Australian Academy of Science, is a past President of the Society for Crystallographers in Australia and New Zealand and former member of the Scientific Advisory Committee of the Australian Synchrotron.

Search Professor Jenny Martin’s works on UQ eSpace

210 works between 1984 and 2022
All (210) Journal Article (177) Book Chapter (9) Conference Publication (19) Other Outputs (5)

1 - 20 of 210 works

Featured

2013

Journal Article

Sexism: conferences should seek a balance

Martin, Jennifer L. (2013). Sexism: conferences should seek a balance. Nature, 493 (7432), 305-305. doi: 10.1038/493305c

Sexism: conferences should seek a balance

Featured

2012

Journal Article

Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

Christie, Michelle P., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Jarrott, Russell J., Chen, Kai-En, Duff, Anthony P., Callow, Philip, Collins, Brett M., James, David E. and Martin, Jennifer L. (2012). Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide. Proceedings of the National Academy of Sciences of the United States of America, 109 (25), 9816-9821. doi: 10.1073/pnas.1116975109

Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

Featured

2011

Journal Article

Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation

Hu, Shu-Hong, Christie, Michelle P., Saez, Natalie J., Latham, Catherine F., Jarrott, Russell, Lua, Linda H. L., Collins, Brett M. and Martin, Jennifer L. (2011). Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America, 108 (3), 1040-1045. doi: 10.1073/pnas.0914906108

Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation

Featured

2009

Journal Article

DSB proteins and bacterial pathogenicity

Heras, B, Shouldice, S. R., Totsika, M, Scanlon, M. J., Schembri, M. A. and Martin, J. L. (2009). DSB proteins and bacterial pathogenicity. Nature Reviews Microbiology, 7 (3), 215-225. doi: 10.1038/nrmicro2087

DSB proteins and bacterial pathogenicity

Featured

2007

Journal Article

Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins

Hu, S. H., Latham, C. F., Gee, C. L., James, D. E. and Martin, J. L. (2007). Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins. Proceedings of The National Academy of Sciences of The United States of America, 104 (21), 8773-8778. doi: 10.1073/pnas.0701124104

Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins

Featured

1996

Journal Article

The 1.1 angstrom crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus

Hu, Shu-Hong, Gehrmann, John, Guddat, Luke W., Alewood, Paul F., Craik, David J. and Martin, Jennifer L. (1996). The 1.1 angstrom crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus. Structure, 4 (4), 417-423. doi: 10.1016/S0969-2126(96)00047-0

The 1.1 angstrom crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus

Featured

1995

Journal Article

Thioredoxin - a Fold for All Reasons

Martin, JL (1995). Thioredoxin - a Fold for All Reasons. Structure, 3 (3), 245-250. doi: 10.1016/S0969-2126(01)00154-X

Thioredoxin - a Fold for All Reasons

Featured

1993

Journal Article

Crystal-Structure of the Dsba Protein Required for Disulfide Bond Formation In-Vivo

Martin, JL, Bardwell, Jca and Kuriyan, J (1993). Crystal-Structure of the Dsba Protein Required for Disulfide Bond Formation In-Vivo. Nature, 365 (6445), 464-468. doi: 10.1038/365464a0

Crystal-Structure of the Dsba Protein Required for Disulfide Bond Formation In-Vivo

Featured

1991

Journal Article

Glucose Analog Inhibitors of Glycogen-Phosphorylase - the Design of Potential-Drugs for Diabetes

Martin, JL, Veluraja, K, Ross, K, Johnson, LN, Fleet, Gwj, Ramsden, NG, Bruce, I, Orchard, MG, Oikonomakos, NG, Papageorgiou, AC, Leonidas, DD and Tsitoura, HS (1991). Glucose Analog Inhibitors of Glycogen-Phosphorylase - the Design of Potential-Drugs for Diabetes. Biochemistry, 30 (42), 10101-10116. doi: 10.1021/bi00106a006

Glucose Analog Inhibitors of Glycogen-Phosphorylase - the Design of Potential-Drugs for Diabetes

Featured

1990

Journal Article

Comparison of the Binding of Glucose and Glucose 1-Phosphate Derivatives to T-State Glycogen Phosphorylase-B

Martin, JL, Johnson, LN and Withers, SG (1990). Comparison of the Binding of Glucose and Glucose 1-Phosphate Derivatives to T-State Glycogen Phosphorylase-B. Biochemistry, 29 (48), 10745-10757. doi: 10.1021/bi00500a005

Comparison of the Binding of Glucose and Glucose 1-Phosphate Derivatives to T-State Glycogen Phosphorylase-B

Featured

1984

Journal Article

Functional-Group Contributions to Drug Receptor Interactions

Andrews, PR, Craik, DJ and Martin, JL (1984). Functional-Group Contributions to Drug Receptor Interactions. Journal of Medicinal Chemistry, 27 (12), 1648-1657. doi: 10.1021/jm00378a021

Functional-Group Contributions to Drug Receptor Interactions

2022

Journal Article

Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis

Jarrott, Russell J., Furlong, Emily J., Petit, Guillaume A., Drew, David, Martin, Jennifer L. and Halili, Maria A. (2022). Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis. Protein Expression and Purification, 193 106047, 106047. doi: 10.1016/j.pep.2022.106047

Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis

2022

Journal Article

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

Petit, Guillaume A., Hong, Yaoqin, Djoko, Karrera Y., Whitten, Andrew E., Furlong, Emily J., McCoy, Airlie J., Gulbis, Jacqueline M., Totsika, Makrina, Martin, Jennifer L. and Halili, Maria A. (2022). The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity. Acta Crystallographica Section D Structural Biology, 78 (3), 337-352. doi: 10.1107/s2059798322000729

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

2022

Journal Article

Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA

Petit, Guillaume A., Mohanty, Biswaranjan, McMahon, Róisín M., Nebl, Stefan, Hilko, David H., Wilde, Karyn L., Scanlon, Martin J., Martin, Jennifer L. and Halili, Maria A. (2022). Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallographica Section D Structural Biology, 78 (1), 75-90. doi: 10.1107/s2059798321011475

Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA

2021

Journal Article

Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities

Subedi, Pramod, Paxman, Jason J., Wang, Geqing, Hor, Lilian, Hong, Yaoqin, Verderosa, Anthony D., Whitten, Andrew E., Panjikar, Santosh, Santos-Martin, Carlos F., Martin, Jennifer L., Totsika, Makrina and Heras, Begoña (2021). Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities. Antioxidants and Redox Signaling, 35 (1), 21-39. doi: 10.1089/ars.2020.8218

Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities

2021

Journal Article

Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain

Cotrim, Camila A., Jarrott, Russell J., Whitten, Andrew E., Choudhury, Hassanul G., Drew, David and Martin, Jennifer L. (2021). Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain. Frontiers in Chemistry, 9 667803, 1-14. doi: 10.3389/fchem.2021.667803

Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain

2021

Journal Article

Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance

Dhouib, Rabeb, Vagenas, Dimitrios, Hong, Yaoqin, Verderosa, Anthony D., Martin, Jennifer L., Heras, Begoña and Totsika, Makrina (2021). Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance. FASEB BioAdvances, 3 (4), 231-242. doi: 10.1096/fba.2020-00100

Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance

2020

Journal Article

Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity

Gor, Mian-Chee, Vezina, Ben, McMahon, Róisín M., King, Gordon J., Panjikar, Santosh, Rehm, Bernd H. A., Martin, Jennifer L. and Smith, Andrew T. (2020). Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity. Scientific Reports, 10 (1) 17398, 17398. doi: 10.1038/s41598-020-74332-1

Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity

2020

Journal Article

NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei

Nebl, Stefan, Alwan, Wesam S., Williams, Martin L., Sharma, Gaurav, Taylor, Ashley, Doak, Bradley C., Wilde, Karyn L., McMahon, Róisín M., Halili, Maria A., Martin, Jennifer L., Capuano, Ben, Fenwick, R. Bryn, Mohanty, Biswaranjan and Scanlon, Martin J. (2020). NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei. Journal of Biomolecular NMR, 74 (10-11), 595-611. doi: 10.1007/s10858-020-00339-5

NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei

2020

Journal Article

Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets

Vezina, Ben, Petit, Guillaume A., Martin, Jennifer L. and Halili, Maria A. (2020). Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets. PloS One, 15 (11) e0241306, 1-21. doi: 10.1371/journal.pone.0241306

Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets

Availability

Emerita Professor Jenny Martin is:
Not available for supervision

Supervision history

Completed supervision

Enquiries

Contact Emerita Professor Jenny Martin directly for media enquiries about:

  • antibacterials
  • Antibiotic discovery
  • antibiotics
  • bacteria
  • bacterial infection
  • Crystallography - protein
  • diabetes
  • drug discovery
  • Enzyme inhibition
  • infection
  • inflammation
  • insulin
  • Protein crystallography
  • Protein function
  • Protein structure
  • Proteins
  • science policy
  • scientific leadership
  • superbugs
  • women in science

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