
Overview
Background
Jenny Martin trained as a pharmacist at the Victorian College of Pharmacy (VCP), where she was awarded the Gold Medal for top student over the BPharm course. After completing an MPharm in computational chemistry at the College, Jenny moved to Oxford University for a PhD by research in protein crystallography and drug design. Her DPhil was supported by a prestigious 1851 Science Research Scholarship and several other competitive scholarships. Jenny then undertook two years of postdoctoral research at Rockefeller University in New York, before returning to Australia in 1993 to establish the first protein crystallography laboratory in Queensland. Since then, she has held ARC QEII, ARC Professorial and NHMRC Fellowships and is currently an ARC Australian Laureate Fellow at the Institute for Molecular Bioscience, University of Queensland. Jenny is the recipient of many honours including the ASBMB Roche Medal, the Queensland Smart Women Smart State Research Scientist award, and the Women in Biotech Outstanding Outstanding Biotechnology Achievement Award.
Availability
- Emerita Professor Jenny Martin is:
- Not available for supervision
- Media expert
Qualifications
- Bachelor of Pharmacy, Victoria University
- Masters (Coursework), Victoria University
- Doctor of Philosophy, University of Oxford
Research impacts
Prof Martin has contributed to knowledge through more than 110 crystal structures deposited into the protein data bank. She has also contributed to the development of patented antidiabetics, HIV-protease inhibitors, and patents leading to the development of conotoxin drugs that progressed to clinical trials. In addition, through a consultancy with PanBIO (now Inverness Medical Innovations) Prof Martin contributed to a patented diagnostic for herpes simplex virus. She has also held ARC Linkage projects with biotech companies Alchemia, Hexima and Biota leading to fundamental and applied research outcomes. As a leader in her field, Jenny has chaired the National Committee for Crystallography of the Australian Academy of Science, is a past President of the Society for Crystallographers in Australia and New Zealand and former member of the Scientific Advisory Committee of the Australian Synchrotron.
Works
Search Professor Jenny Martin’s works on UQ eSpace
1996
Journal Article
Three-dimensional structure of the alpha-conotoxin GI at 1.2 angstrom resolution
Guddat, LW, Martin, JL, Shan, L, Edmundson, AB and Gray, WR (1996). Three-dimensional structure of the alpha-conotoxin GI at 1.2 angstrom resolution. Biochemistry, 35 (35), 11329-11335. doi: 10.1021/bi960820h
1996
Journal Article
Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode
March, D. R., Abbenante, G., Bergman, D. A., Brinkworth, R. I., Wickramasinghe, W., Begun, J., Martin, J. L. and Fairlie, D. P. (1996). Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. Journal of The American Chemical Society, 118 (14), 3375-3379. doi: 10.1021/ja953790z
1996
Journal Article
Crystallization and preliminary X-ray crystallographic studies of Escherichia coli xanthine phosphoribosyltransferase
Vos, S, deJersey, J and Martin, JL (1996). Crystallization and preliminary X-ray crystallographic studies of Escherichia coli xanthine phosphoribosyltransferase. Journal of Structural Biology, 116 (2), 330-334. doi: 10.1006/jsbi.1996.0050
1996
Journal Article
Protein crystallography and examples of its applications in medicinal chemistry
Martin, JL (1996). Protein crystallography and examples of its applications in medicinal chemistry. Current Medicinal Chemistry, 3 (6), 419-436. doi: 10.2174/0929867303666220307175609
1995
Journal Article
Regioselective Structural and Functional Mimicry of Peptides - Design of Hydrolytically-Stable Cyclic Peptidomimetic Inhibitors of Hiv-1 Protease
Abbenante, G, March, DR, Bergman, DA, Hunt, PA, Garnham, B, Dancer, RJ, Martin, JL and Fairlie, DP (1995). Regioselective Structural and Functional Mimicry of Peptides - Design of Hydrolytically-Stable Cyclic Peptidomimetic Inhibitors of Hiv-1 Protease. Journal of the American Chemical Society, 117 (41), 10220-10226. doi: 10.1021/ja00146a007
1993
Journal Article
Crystallographic Binding-Studies On the Allosteric Inhibitor Glucose-6-Phosphate to T-State Glycogen Phosphorylase-B
Johnson, LN, Snape, P, Martin, JL, Acharya, KR, Barford, D and Oikonomakos, NG (1993). Crystallographic Binding-Studies On the Allosteric Inhibitor Glucose-6-Phosphate to T-State Glycogen Phosphorylase-B. Journal of Molecular Biology, 232 (1), 253-267. doi: 10.1006/jmbi.1993.1380
1993
Journal Article
Crystallization of Dsba, An Escherichia-Coli Protein Required for Disulfide Bond Formation Invivo
Martin, JL, Waksman, G, Bardwell, Jca, Beckwith, J and Kuriyan, J (1993). Crystallization of Dsba, An Escherichia-Coli Protein Required for Disulfide Bond Formation Invivo. Journal of Molecular Biology, 230 (3), 1097-1100. doi: 10.1006/jmbi.1993.1226
1988
Journal Article
Channels At the Catalytic Site of Glycogen Phosphorylase-B - Binding and Kinetic-Studies with the Beta-Glycosidase Inhibitor D-Gluconohydroximo-1,5-Lactone N-Phenylurethane
Barford, D, Schwabe, Jwr, Oikonomakos, NG, Acharya, KR, Hajdu, J, Papageorgiou, AC, Martin, JL, Knott, Jca, Vasella, A and Johnson, LN (1988). Channels At the Catalytic Site of Glycogen Phosphorylase-B - Binding and Kinetic-Studies with the Beta-Glycosidase Inhibitor D-Gluconohydroximo-1,5-Lactone N-Phenylurethane. Biochemistry, 27 (18), 6733-6741. doi: 10.1021/bi00418a014
1987
Journal Article
Conformation-activity relationships of opiate analgesics
Martin, Jennifer Louise and Andrews, Peter (1987). Conformation-activity relationships of opiate analgesics. Journal of Computer-Aided Molecular Design, 1 (1), 53-72. doi: 10.1007/BF01680557
1986
Journal Article
Central-Nervous-System Drug Design
Andrews, PR, Lloyd, EJ, Martin, JL and Munro, Sla (1986). Central-Nervous-System Drug Design. Journal of Molecular Graphics, 4 (1), 41-&.
Supervision
Availability
- Emerita Professor Jenny Martin is:
- Not available for supervision
Supervision history
Completed supervision
-
2018
Doctor Philosophy
The disulfide oxidative pathway in Chlamydia trachomatis
Principal Advisor
Other advisors: Professor Brett Collins
-
2014
Doctor Philosophy
Structural & Functional Characterization of Bacterial TRX-fold proteins
Principal Advisor
Other advisors: Professor Mark Schembri
-
2014
Doctor Philosophy
Design, Synthesis and Evaluation of Peptides and Peptidomimetics Inhibiting the Bacterial DsbA-DsbB Interaction
Principal Advisor
Other advisors: Professor David Fairlie
-
-
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2011
Doctor Philosophy
A structural genomics approach to the structure determination of macrophage proteins
Principal Advisor
Other advisors: Professor Linda Lua
-
2010
Doctor Philosophy
Characterization of interactions formed by the SNARE Syntaxin4 protein and the Sec/Munc protein Munc 18c
Principal Advisor
Other advisors: Professor Linda Lua
-
2010
Doctor Philosophy
Substrate, inhibitor, and mutational studies of the human adrenaline synthesising enzyme Phenylethanolamine N-Methyltransferase
Principal Advisor
-
2008
Doctor Philosophy
Structural and functional characterization of DsbA homologues from Wolbachia pipientis
Principal Advisor
-
2005
Doctor Philosophy
Molecular Interactions of Munc18c and GLUT4-associated SNARE proteins
Principal Advisor
-
2003
Doctor Philosophy
PROTEIN FOLDING: STRUCTURE-FUNCTION STUDIES ON CycY, A REDUCING DISULPHIDE OXIDOREDUCTASE
Principal Advisor
-
2019
Doctor Philosophy
Characterisation of proteins essential to vesicle membrane fusion
Associate Advisor
Other advisors: Professor Brett Collins
-
2019
Doctor Philosophy
Structural and functional studies of suppressor of copper sensitivity proteins from Proteus mirabilis
Associate Advisor
Other advisors: Professor Brett Collins
-
2005
Doctor Philosophy
DIVERSITY AND STRUCTURE-ACTIVITY RELATIONSHIPS OF THE CYCLOTIDES
Associate Advisor
Other advisors: Professor David Craik
-
2004
Doctor Philosophy
TOWARDS THE SYNTHESIS OF BIOLOGICALLY ACTIVE CARBOHYDRATES, AND CARBOHYDRATE MIMETICS
Associate Advisor
Media
Enquiries
Contact Emerita Professor Jenny Martin directly for media enquiries about:
- antibacterials
- Antibiotic discovery
- antibiotics
- bacteria
- bacterial infection
- Crystallography - protein
- diabetes
- drug discovery
- Enzyme inhibition
- infection
- inflammation
- insulin
- Protein crystallography
- Protein function
- Protein structure
- Proteins
- science policy
- scientific leadership
- superbugs
- women in science
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