Emerita Professor Jenny Martin
Emerita Professor

Jenny Martin

Email: 

Background

Jenny Martin trained as a pharmacist at the Victorian College of Pharmacy (VCP), where she was awarded the Gold Medal for top student over the BPharm course. After completing an MPharm in computational chemistry at the College, Jenny moved to Oxford University for a PhD by research in protein crystallography and drug design. Her DPhil was supported by a prestigious 1851 Science Research Scholarship and several other competitive scholarships. Jenny then undertook two years of postdoctoral research at Rockefeller University in New York, before returning to Australia in 1993 to establish the first protein crystallography laboratory in Queensland. Since then, she has held ARC QEII, ARC Professorial and NHMRC Fellowships and is currently an ARC Australian Laureate Fellow at the Institute for Molecular Bioscience, University of Queensland. Jenny is the recipient of many honours including the ASBMB Roche Medal, the Queensland Smart Women Smart State Research Scientist award, and the Women in Biotech Outstanding Outstanding Biotechnology Achievement Award.

Availability

Emerita Professor Jenny Martin is:
Not available for supervision
Media expert

Qualifications

  • Bachelor of Pharmacy, Victoria University
  • Masters (Coursework), Victoria University
  • Doctor of Philosophy, University of Oxford

Research impacts

Prof Martin has contributed to knowledge through more than 110 crystal structures deposited into the protein data bank. She has also contributed to the development of patented antidiabetics, HIV-protease inhibitors, and patents leading to the development of conotoxin drugs that progressed to clinical trials. In addition, through a consultancy with PanBIO (now Inverness Medical Innovations) Prof Martin contributed to a patented diagnostic for herpes simplex virus. She has also held ARC Linkage projects with biotech companies Alchemia, Hexima and Biota leading to fundamental and applied research outcomes. As a leader in her field, Jenny has chaired the National Committee for Crystallography of the Australian Academy of Science, is a past President of the Society for Crystallographers in Australia and New Zealand and former member of the Scientific Advisory Committee of the Australian Synchrotron.

Search Professor Jenny Martin’s works on UQ eSpace

210 works between 1984 and 2022
All (210) Journal Article (177) Book Chapter (9) Conference Publication (19) Other Outputs (5)

21 - 40 of 210 works

2020

Journal Article

How to Make the Invisible Women of STEM Visible

Halili, Maria A. and Martin, Jennifer L. (2020). How to Make the Invisible Women of STEM Visible. Australian Journal of Chemistry, 73 (3), 75-77. doi: 10.1071/CH19286

How to Make the Invisible Women of STEM Visible

2019

Journal Article

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development

Christensen, Signe, Halili, Maria A., Strange, Natalie, Petit, Guillaume A., Huston, Wilhelmina M., Martin, Jennifer L. and McMahon, Róisín M. (2019). Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development. PLoS One, 14 (9) e0222595, e0222595. doi: 10.1371/journal.pone.0222595

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development

2019

Journal Article

A structural overview of the zinc transporters in the cation diffusion facilitator family

Cotrim, Camila A., Jarrott, Russell J., Martin, Jennifer L. and Drew, David (2019). A structural overview of the zinc transporters in the cation diffusion facilitator family. Acta Crystallographica Section D: Structural Biology, 75 (4), 357-367. doi: 10.1107/S2059798319003814

A structural overview of the zinc transporters in the cation diffusion facilitator family

2019

Journal Article

Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017)

Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begona, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A. and Martin, Jennifer L. (2019). Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017). Nature Communications, 10 (1) 976, 976. doi: 10.1038/s41467-019-08920-9

Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017)

2019

Journal Article

Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis

Furlong, Emily J., Kurth, Fabian, Premkumar, Lakshmanane, Whitten, Andrew E. and Martin, Jennifer L. (2019). Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis. Acta Crystallographica Section D-Structural Biology, 75 (3), 296-307. doi: 10.1107/S2059798319000081

Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis

2019

Journal Article

The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase

Walden, Patricia M., Whitten, Andrew E., Premkumar, Lakshmanane, Halili, Maria A., Heras, Begona, King, Gordon J. and Martin, Jennifer L. (2019). The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase. Acta Crystallographica Section D: Structural Biology, 75 (3), 283-295. doi: 10.1107/S2059798318018442

The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase

2019

Journal Article

Life inside and out: making and breaking protein disulfide bonds in Chlamydia

Christensen, Signe, McMahon, Róisín M., Martin, Jennifer L. and Huston, Wilhelmina M. (2019). Life inside and out: making and breaking protein disulfide bonds in Chlamydia. Critical Reviews in Microbiology, 45 (1), 33-50. doi: 10.1080/1040841x.2018.1538933

Life inside and out: making and breaking protein disulfide bonds in Chlamydia

2019

Book Chapter

Studying Munc18:Syntaxin interactions using small-angle scattering

Whitten, Andrew E., Jarrott, Russell J., Hu, Shu-Hong, Duff, Anthony P., King, Gordon J., Martin, Jennifer L. and Christie, Michelle P. (2019). Studying Munc18:Syntaxin interactions using small-angle scattering. SNAREs: methods and protocols. (pp. 115-144) New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-8760-3_7

Studying Munc18:Syntaxin interactions using small-angle scattering

2018

Journal Article

Disulfide isomerase activity of the dynamic, trimeric Proteus mirabilis ScsC protein is primed by the tandem immunoglobulin-fold domain of ScsB

Furlong, Emily J., Choudhury, Hassanul G., Kurth, Fabian, Duff, Anthony P., Whitten, Andrew E. and Martin, Jennifer L. (2018). Disulfide isomerase activity of the dynamic, trimeric Proteus mirabilis ScsC protein is primed by the tandem immunoglobulin-fold domain of ScsB. The Journal of Biological Chemistry, 293 (16), 5793-5805. doi: 10.1074/jbc.RA118.001860

Disulfide isomerase activity of the dynamic, trimeric Proteus mirabilis ScsC protein is primed by the tandem immunoglobulin-fold domain of ScsB

2018

Journal Article

Virulence of the melioidosis pathogen Burkholderia pseudomallei requires the oxidoreductase membrane protein DsbB

McMahon, Róisín M., Ireland, Philip M., Sarovich, Derek S., Petit, Guillaume, Jenkins, Christopher H., Sarkar-Tyson, Mitali, Currie, Bart J. and Martin, Jennifer L. (2018). Virulence of the melioidosis pathogen Burkholderia pseudomallei requires the oxidoreductase membrane protein DsbB. Infection and Immunity, 86 (5) e00938-17, e00938-17. doi: 10.1128/IAI.00938-17

Virulence of the melioidosis pathogen Burkholderia pseudomallei requires the oxidoreductase membrane protein DsbB

2018

Journal Article

Inhibition of diverse DsbA enzymes in multi-DsbA encoding pathogens

Totsika, Makrina, Vagenas, Dimitrios, Paxman, Jason J., Wang, Geqing, Dhouib, Rabeb, Sharma, Pooja, Martin, Jennifer L., Scanlon, Martin J. and Heras, Begoña (2018). Inhibition of diverse DsbA enzymes in multi-DsbA encoding pathogens. Antioxidants and Redox Signaling, 29 (7) ars.2017.7104, 653-666. doi: 10.1089/ars.2017.7104

Inhibition of diverse DsbA enzymes in multi-DsbA encoding pathogens

2018

Journal Article

Exploring positive survivorship experiences of Indigenous Australian cancer patients

Tam, Laura, Garvey, Gail, Meiklejohn, Judith, Martin, Jennifer, Adams, Jon, Walpole, Euan, Fay, Michael and Valery, Patricia (2018). Exploring positive survivorship experiences of Indigenous Australian cancer patients. International Journal of Environmental Research and Public Health, 15 (1) 135, 135. doi: 10.3390/ijerph15010135

Exploring positive survivorship experiences of Indigenous Australian cancer patients

2018

Other Outputs

X-ray diffraction images related to PDB entry 4XVW

Kurth, Fabian, Furlong, Emily J, Premkumar, Lakshmanane and Martin, Jennifer Louise (2018). X-ray diffraction images related to PDB entry 4XVW. The University of Queensland. (Dataset) doi: 10.14264/uql.2018.26

X-ray diffraction images related to PDB entry 4XVW

2018

Other Outputs

X-ray diffraction images related to PDB entry 5ID4

Furlong, Emily J, Kurth, Fabian, Choudhury, Hassanul and Martin, Jennifer Louise (2018). X-ray diffraction images related to PDB entry 5ID4. The University of Queensland. (Dataset) doi: 10.14264/uql.2018.27

X-ray diffraction images related to PDB entry 5ID4

2018

Other Outputs

X-ray diffraction images related to PDB entry 5IDR

Furlong, Emily J, Kurth, Fabian, Choudhury, Hassanul and Martin, Jennifer Louise (2018). X-ray diffraction images related to PDB entry 5IDR. The University of Queensland. (Dataset) doi: 10.14264/uql.2018.25

X-ray diffraction images related to PDB entry 5IDR

2018

Other Outputs

X-ray diffraction images related to PDB entry 6C29

Furlong, Emily J, Choudhury, Hassanul G, Kurth, Fabian and Martin, Jennifer Louise (2018). X-ray diffraction images related to PDB entry 6C29. The University of Queensland. (Dataset) doi: 10.14264/uql.2018.671

X-ray diffraction images related to PDB entry 6C29

2017

Journal Article

Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins

Christie, Michelle P., Hu, Shu-Hong, Whitten, Andrew E., Rehman, Asma, Jarrott, Russell J., King, Gordon J., Collins, Brett M. and Martin, Jennifer L. (2017). Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins. PloS one, 12 (10) e0187302, 1-16. doi: 10.1371/journal.pone.0187302

Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins

2017

Journal Article

The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly

Rehman, Asma, Hu, Shu-Hong , Tnimov, Zakir, Whitten, Andrew E., King, Gordon J., Jarrott, Russell J., Norwood, Suzanne J., Alexandrov, Kirill, Collins, Brett M., Christie, Michelle P. and Martin, Jennifer L. (2017). The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly. PLoS One, 12 (8) e0183366, e0183366. doi: 10.1371/journal.pone.0183366

The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly

2017

Journal Article

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begona, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A. and Martin, Jennifer L. (2017). A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance. Nature Communications, 8 (1) 16065, 16065. doi: 10.1038/ncomms16065

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

2017

Journal Article

Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia

Valery, Patricia C., Clark, Paul J., McPhail, Steven M., Rahman, Tony, Hayward, Kelly, Martin, Jennifer, Horsfall, Leigh, Volk, Michael L., Skoien, Richard and Powell, Elizabeth (2017). Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia. Internal Medicine Journal, 47 (4), 429-435. doi: 10.1111/imj.13380

Exploratory study into the unmet supportive needs of people diagnosed with cirrhosis in Queensland, Australia

Past funding

  • 2016
    Burkholderia pseudomallei disulfide-forming proteins: structure, function and inhibition (NHMRC Project Grant administered by Griffith University)
    Open grant
  • 2016
    Molecular dissection of the Munc18c:Syntaxin4 complex required for insulin-regulated exocytosis in adipocytes (NHMRC Project Grant administered by Griffith University)
    Griffith University
    Open grant
  • 2016 - 2018
    DsbA inhibitors: from hits to leads
    NHMRC Project Grant
    Open grant
  • 2016
    Structure and function of human zinc transporter membrane proteins
    ARC Discovery Projects
    Open grant
  • 2015
    Protein Analysis Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2016
    Unraveling the dynamic Munc18a:Syntaxin1 interaction required for neurotransmission
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Burkholderia pseudomallei disulfide-forming proteins: structure, function and inhibition
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Molecular dissection of the Munc18c:Syntaxin4 complex required for insulin-regulated exocytosis in adipocytes
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Membrane proteins in innate immunity
    ARC Discovery Projects
    Open grant
  • 2012 - 2013
    Overcoming membrane protein research roadblocks: A Queensland facility for membrane protein production and crystallisation
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2012
    High- throughput Fourier Transform Infrared (FTIR) spectrometer.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2013
    Multi angle light scattering detector for the measurement of absolute molecular weight, size, and conformation of macromolecules in solution
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Auto-iTC200 microcalorimeter for high-throughput molecular interaction analyses
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Freedom Evo 150 robotic worktable: Automated high throughput and long-time course spectrophotometric multiwell plate assay system
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Queensland International Fellowship: Membrane Protein Structure Techniques
    Queensland International Fellowships
    Open grant
  • 2010 - 2013
    Targeting virulence of Pseudomonas aeruginosa by inhibiting oxidative protein folding (ARC Linkage Project Grant, administered by Monash University)
    Monash University
    Open grant
  • 2010
    Combinatorial chemistry (high throughput synthesizer and purification system)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    The development of peptides (mini-proteins) as drugs: improved purification capability
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2014
    Towards antibacterials without resistance
    ARC Australian Laureate Fellowships
    Open grant
  • 2009
    Characterization of the Munc 18c-Sx4 Complex
    Australian Nuclear Science and Technology Organisation
    Open grant
  • 2009 - 2013
    How the SNARE:SM machinery regulates glucose transport in fat cells
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    Design and use of human hematopoietic prostaglandin D2 synthase inhibitors in allergic asthma and bone diseases
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    DsbA inhibitors as potential antimicrobials
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    Inhibitors Of West Nile Virus Protease As Antiviral Drugs
    NHMRC Project Grant
    Open grant
  • 2007 - 2011
    Macrophage proteins: structure, function and e-science
    ARC Discovery Projects
    Open grant
  • 2007 - 2015
    NHMRC Senior Research Fellowship
    NHMRC Research Fellowship
    Open grant
  • 2006 - 2008
    Deciphering the molecular basis of SM regulation of exocytosis
    NHMRC Project Grant
    Open grant
  • 2006
    e-Research Infrastructure for the Molecular and Materials Structure Sciences
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2006 - 2008
    Innovative Approaches to Membrane Protein Crystallography & Drug Discovery
    ARC Discovery Projects
    Open grant
  • 2006
    Small Angle Scattering Facility for the Materials and Biological Sciences
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2008
    Enhancement of plant proteinase inhibitors for the protection of crop plants against insect attack
    ARC Linkage Projects
    Open grant
  • 2005
    A New Generation Biosensor and Fluorescence Facility for Proteomic
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2007
    Deciphering the molecular steps leading to the potentiation of neuronal exocytosis by arachidonic acid
    NHMRC Project Grant
    Open grant
  • 2004
    Structural biology of macromolecular assemblies as part of the visual cell program
    University of Queensland Research Development Grants Scheme
    Open grant
  • 2004 - 2006
    Structure and function of novel macrophage proteins using high throughput crystallography
    ARC Discovery Projects
    Open grant
  • 2004
    The Australian Protease Network
    ARC Seed Funding for Research Networks
    Open grant
  • 2003
    Application for Support for Access to Major Research Facilities Program - Project title: Structural Studies on PNMT, Mouse Latexin, Insect Ferritin
    Australian Nuclear Science and Technology Organisation
    Open grant
  • 2003
    Dynamic Light Scattering Instrument
    NHMRC Equipment Grant
    Open grant
  • 2003 - 2005
    Investigating the structure, function and inhibition of the adrenaline-synthesizing enzyme PNMT
    ARC Discovery Projects
    Open grant
  • 2003 - 2004
    Structural studies on carbohydrate modifying enzymes
    ARC Linkage Projects
    Open grant
  • 2003
    Structural Studies on the Regulation of SNARE Proteins by Munc18c
    University of Queensland Research Development Grants Scheme
    Open grant
  • 2003 - 2005
    Structure, Function And Regulation Of Human Cytosolic Sulfotransferases
    NHMRC Project Grant
    Open grant
  • 2002
    AUSTRALIAN SYNCHROTRON RESEARCH PROGRAM: Support for access to the Advanced Photon Source to visit BIOCARS
    Australian Nuclear Science and Technology Organisation
    Open grant
  • 2000
    Chromatography system for structural biology
    Ramaciotti Foundation
    Open grant
  • 2000 - 2002
    Design and development of inhibitors of the dengue virus protease as antiviral agents
    NHMRC Project Grant
    Open grant
  • 2000 - 2002
    Structural studies on SNARE proteins involved in insulin action
    NHMRC Project Grant
    Open grant
  • 2000 - 2002
    Structural studies on the adrenaline-synthesising enzyme, PNMT
    ARC Australian Research Council (Large grants)
    Open grant
  • 1999 - 2000
    Structural determination of the protein folding factor CycY
    Australian Nuclear Science and Technology Organisation
    Open grant
  • 1999 - 2003
    Applications of Protein Crystallography in Drug Design
    ARC Australian Senior Research Fellowships
    Open grant
  • 1999
    Expression and crystallization of SNARE proteins from adipocytes
    ARC Australian Research Council (Small grants)
    Open grant
  • 1999 - 2001
    Protein Disulfide Exchange and Protein Folding in vivo: Structural Studies of Disulfide Oxidoreductases
    ARC Australian Research Council (Large grants)
    Open grant
  • 1999 - 2001
    Structural, Functional and Genetic Characterisation of Human Sulfotransferases
    NHMRC Project Grant
    Open grant
  • 1998
    Plant pyruvate phosphate dikinase and human aryl sulfotransferase 3
    Australian Nuclear Science and Technology Organisation
    Open grant
  • 1997
    Structure-function studies on human phenylethanolamine N-methyltransferase
    UQ External Support Enabling Grant
    Open grant
  • 1996 - 1998
    Structural studies on purine phosphoribosyltransferases (PRTases)
    ARC Australian Research Council (Large grants)
    Open grant
  • 1996
    Structure determination by NMR of the disulfide-dithiol exchange protein TcpG
    ARC Australian Research Council (Small grants)
    Open grant
  • 1995 - 1997
    Structural studies on reduced DsbA and DsbA analogues
    ARC Australian Research Council (Large grants)
    Open grant
  • 1994 - 2006
    Design of inhibitors of epinephrine biosynthesis.
    University of Kansas
    Open grant

Availability

Emerita Professor Jenny Martin is:
Not available for supervision

Supervision history

Completed supervision

Enquiries

Contact Emerita Professor Jenny Martin directly for media enquiries about:

  • antibacterials
  • Antibiotic discovery
  • antibiotics
  • bacteria
  • bacterial infection
  • Crystallography - protein
  • diabetes
  • drug discovery
  • Enzyme inhibition
  • infection
  • inflammation
  • insulin
  • Protein crystallography
  • Protein function
  • Protein structure
  • Proteins
  • science policy
  • scientific leadership
  • superbugs
  • women in science

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au