Professor Linda Lua
Professor

Linda Lua

Email: 

Availability

Professor Linda Lua is:
Not available for supervision

Fields of research

Biological control Bioprocessing, bioproduction and bioproducts Environmental biotechnology Industrial biotechnology

Qualifications

  • Bachelor (Honours) of Applied Science, The University of Queensland
  • Doctor of Philosophy of Bioengineering, The University of Queensland

Research interests

  • Protein Technologies

  • Bioengineering virus-like particle as vaccines

Search Professor Linda Lua’s works on UQ eSpace

85 works between 1999 and 2024
All (85) Journal Article (70) Book Chapter (3) Conference Publication (9) Other Outputs (3)

1 - 20 of 85 works

2024

Journal Article

Effective Parallel Evaluation of Molecular Design, Expression and Bioactivity of Novel Recombinant Butyrylcholinesterase Medical Countermeasures

Allard, Joanne L., Aguirre, Miguel, Gupta, Ruchi, Chua, Sheena.M.H., Shields, Katherine A. and Lua, Linda.H.L. (2024). Effective Parallel Evaluation of Molecular Design, Expression and Bioactivity of Novel Recombinant Butyrylcholinesterase Medical Countermeasures. Chemico-Biological Interactions 111219, 111219. doi: 10.1016/j.cbi.2024.111219

Effective Parallel Evaluation of Molecular Design, Expression and Bioactivity of Novel Recombinant Butyrylcholinesterase Medical Countermeasures

2022

Journal Article

Design and optimization of membrane chromatography for monoclonal antibody charge variant separation

Nadar, Sathish, Somasundaram, Balaji, Charry, Marcela, Billakanti, Jagan, Shave, Evan, Baker, Kym and Lua, Linda H. L. (2022). Design and optimization of membrane chromatography for monoclonal antibody charge variant separation. Biotechnology Progress, 38 (6) e3288, 1-15. doi: 10.1002/btpr.3288

Design and optimization of membrane chromatography for monoclonal antibody charge variant separation

2022

Journal Article

Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning

Allard, Joanne L., Shields, Katherine A., Munro, Trent P. and Lua, Linda H.L. (2022). Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning. Chemico-Biological Interactions, 363 109996, 109996. doi: 10.1016/j.cbi.2022.109996

Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning

2022

Book Chapter

Protein expression optimization strategies in E. coli: a tailored approach in strain selection and parallelizing expression conditions

Tang, Shyn Ric, Somasundaram, Balaji and Lua, Linda H. L. (2022). Protein expression optimization strategies in E. coli: a tailored approach in strain selection and parallelizing expression conditions. Insoluble proteins: methods and protocols. (pp. 93-111) edited by Elena Garcia Fruitos and Anna Arı´s Giralt. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1859-2_5

Protein expression optimization strategies in E. coli: a tailored approach in strain selection and parallelizing expression conditions

2021

Journal Article

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

Yap, Kuok, Du, Junqiao, Rehm, Fabian B. H., Tang, Shyn Ric, Zhou, Yan, Xie, Jing, Wang, Conan K., de Veer, Simon J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2021). Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature Protocols, 16 (3), 1-23. doi: 10.1038/s41596-020-00483-0

Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases

2021

Journal Article

Ambient temperature stable, scalable COVID-19 polymer particle vaccines induce protective immunity

Chen, Shuxiong, Evert, Benjamin, Adeniyi, Adetayo, Salla-Martret, Mercè, Lua, Linda H.-L., Ozberk, Victoria, Pandey, Manisha, Good, Michael F., Suhrbier, Andreas, Halfmann, Peter, Kawaoka, Yoshihiro and Rehm, Bernd H. A. (2021). Ambient temperature stable, scalable COVID-19 polymer particle vaccines induce protective immunity. Advanced Healthcare Materials, 11 (3) 2102089, 2102089. doi: 10.1002/adhm.202102089

Ambient temperature stable, scalable COVID-19 polymer particle vaccines induce protective immunity

2021

Journal Article

Current status and future challenges in transitioning to continuous bioprocessing of virus-like particles

Mittal, Manya, Banerjee, Manidipa, Lua, Linda H. L. and Rathore, Anurag S. (2021). Current status and future challenges in transitioning to continuous bioprocessing of virus-like particles. Journal of Chemical Technology and Biotechnology, 97 (9) jctb.6821, 2376-2385. doi: 10.1002/jctb.6821

Current status and future challenges in transitioning to continuous bioprocessing of virus-like particles

2020

Journal Article

Intensified downstream processing of monoclonal antibodies using membrane technology

Nadar, Sathish, Shooter, Gary, Somasundaram, Balaji, Shave, Evan, Baker, Kym and Lua, Linda H.L. (2020). Intensified downstream processing of monoclonal antibodies using membrane technology. Biotechnology Journal, 16 (3) 2000309, 1-11. doi: 10.1002/biot.202000309

Intensified downstream processing of monoclonal antibodies using membrane technology

2020

Journal Article

To our readers: Important notice

Poland, Gregory A., van Dijk, Nicolette, Altmann, Danny, Borrow, Ray, Hung, Ivan, Ishii, Ken, Jacobsen, Steve, Krammer, Florian, Larson, Heidi, Lua, Linda, Middelberg, Anton, Nelson, Jennifer, Neuzil, Kathy, Nohynek, Hanna, Reingold, Art, van den Hurk, Sylvia, Kennedy, Rick B. and Sadarangani, Sapna (2020). To our readers: Important notice. Vaccine, 38 (35). doi: 10.1016/j.vaccine.2020.07.001

To our readers: Important notice

2020

Journal Article

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

Yap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

2020

Journal Article

Protein expression in the baculovirus-insect cell expression system

Adeniyi, Adetayo A. and Lua, Linda Hwee-Lin (2020). Protein expression in the baculovirus-insect cell expression system. Methods in Molecular Biology, 2073, 17-37. doi: 10.1007/978-1-4939-9869-2_2

Protein expression in the baculovirus-insect cell expression system

2019

Journal Article

Vaccine Technology VII: beyond the “decade of vaccines”

Kamen, Amine A., Lua, Linda H. L. and Mukhopadhyay, Tarit K. (2019). Vaccine Technology VII: beyond the “decade of vaccines”. Vaccine, 37 (47), 6931-6932. doi: 10.1016/j.vaccine.2019.09.083

Vaccine Technology VII: beyond the “decade of vaccines”

2019

Journal Article

Evaluation of process simulation as a decisional tool for biopharmaceutical contract development and manufacturing organizations

Pleitt, Kristina, Somasundaram, Balaji, Johnson, Bradley, Shave, Evan and Lua, Linda H.L. (2019). Evaluation of process simulation as a decisional tool for biopharmaceutical contract development and manufacturing organizations. Biochemical Engineering Journal, 150 107252, 107252. doi: 10.1016/j.bej.2019.107252

Evaluation of process simulation as a decisional tool for biopharmaceutical contract development and manufacturing organizations

2019

Journal Article

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses

Pattinson, David J., Apte, Simon H., Wibowo, Nani, Chuan, Yap P., Rivera-Hernandez, Tania, Groves, Penny L., Lua, Linda H., Middelberg, Anton P. J. and Doolan, Denise L. (2019). Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses. Frontiers in Cellular and Infection Microbiology, 9 (JUN) 215, 215. doi: 10.3389/fcimb.2019.00215

Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses

2019

Journal Article

Synthetic biology for bioengineering virus-like particle vaccines

Charlton Hume, Hayley K., Vidigal, João, Carrondo, Manuel J. T., Middelberg, Anton P. J., Roldão, António and Lua, Linda H. L. (2019). Synthetic biology for bioengineering virus-like particle vaccines. Biotechnology and Bioengineering, 116 (4), 919-935. doi: 10.1002/bit.26890

Synthetic biology for bioengineering virus-like particle vaccines

2018

Journal Article

Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges

Somasundaram, Balaji, Pleitt, Kristina, Shave, Evan, Baker, Kym and Lua, Linda H. L. (2018). Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges. Biotechnology and Bioengineering, 115 (12), 2893-2907. doi: 10.1002/bit.26812

Progression of continuous downstream processing of monoclonal antibodies: current trends and challenges

2018

Journal Article

Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides

Walker, Julia A., Robinson, Kye J., Munro, Christopher, Gengenbach, Thomas, Muller, David A., Young, Paul R., Lua, Linda H. L. and Corrie, Simon R. (2018). Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides. Langmuir, 35 (5) acs.langmuir.8b00810, 1266-1272. doi: 10.1021/acs.langmuir.8b00810

Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides

2018

Journal Article

Vaccine Technology VI: innovative and integrated approaches in vaccine development

Palomares, Laura A., Mukhopadhyay, Tarit K., Genzel, Yvonne, Lua, Linda H.L. and Cox, Manon M.J. (2018). Vaccine Technology VI: innovative and integrated approaches in vaccine development. Vaccine, 36 (22), 3061-3063. doi: 10.1016/j.vaccine.2018.03.077

Vaccine Technology VI: innovative and integrated approaches in vaccine development

2018

Journal Article

Baculovirus-driven protein expression in insect cells: a benchmarking study

Stolt-Bergner, Peggy, Benda, Christian, Bergbrede, Tim, Besir, Hüseyin, Celie, Patrick H. N., Chang, Cindy, Drechsel, David, Fischer, Ariane, Geerlof, Arie, Giabbai, Barbara, van den Heuvel, Joop, Huber, Georg, Knecht, Wolfgang, Lehner, Anita, Lemaitre, Regis, Nordén, Kristina, Pardee, Gwynn, Racke, Ines, Remans, Kim, Sander, Astrid, Scholz, Judith, Stadnik, Magda, Storici, Paola, Weinbruch, Daniel, Zaror, Isabel, Lua, Linda H. L. and Suppmann, Sabine (2018). Baculovirus-driven protein expression in insect cells: a benchmarking study. Journal of Structural Biology, 203 (2), 71-80. doi: 10.1016/j.jsb.2018.03.004

Baculovirus-driven protein expression in insect cells: a benchmarking study

2017

Journal Article

Preface: Biosecurity

Lua, Linda H. L. and Fooks, Anthony R. (2017). Preface: Biosecurity. Vaccine, 35 (44), 5947-5948. doi: 10.1016/j.vaccine.2017.08.077

Preface: Biosecurity

Past funding

  • 2021 - 2022
    Scale-down biomanufacturing capabilities to translate health discoveries into clinical applications
    IPF Healthy - Medical Research
    Open grant
  • 2020 - 2023
    Enhancing biopharmaceuticals: a disruptive bioseparation resin technology (ARC Discovery Project administered by Griffith University)
    Griffith University
    Open grant
  • 2019
    Advanced biomanufacturing with versatile yeast expression platform
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2019
    Cyto-Mine to accelerate Cell Line Development for Vaccines and Biopharmaceuticals
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Continuous chromatography system for advanced bioprocessing
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Enabling research and development of next generation mammalian cell-based products
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2017 - 2023
    ARC Training Centre for Biopharmaceutical Innovation
    ARC Industrial Transformation Training Centres
    Open grant
  • 2016 - 2019
    Engineering a nanovaccine for cost-effective influenza poultry vaccination
    ARC Discovery Projects
    Open grant
  • 2016
    Rapid analysis of protein stability and aggregation
    UQ Major Research Facility Fund
    Open grant
  • 2014 - 2016
    Human enterovirus-like particle vaccine development
    Sentinext Therapeutics
    Open grant
  • 2014
    Coxsackievirus-A16 VLP Vaccine Development
    UniQuest Pty Ltd
    Open grant
  • 2012 - 2014
    Expression of EV71 VLPs in insect cells
    UniQuest Pty Ltd
    Open grant
  • 2010 - 2013
    Vaccine Now - Beating Infectious Disease with Rapid Response Technology
    Queensland Government Smart State National and International Research Alliances Program
    Open grant
  • 2007 - 2009
    Terahertz Spectroscopy of Mass-Manufactured Viral Vaccines
    ARC Discovery Projects
    Open grant
  • 2006 - 2007
    Simplified Process Methods for Mass Vaccine Manufacture
    NHMRC Potential Avian Influenza - induced pandemic
    Open grant
  • 2005 - 2008
    Bio-based Functional Materials from Engineered Self-Assembling Peptides (BASE)
    Department of Innovation, Industry, Science and Research - ISL French-Australian Science and Technology Program
    Open grant

Availability

Professor Linda Lua is:
Not available for supervision

Supervision history

Current supervision

  • Doctor Philosophy

    Broad Spectrum Medical Countermeasure development for Organophosphate Compounds

    Principal Advisor

    Other advisors: Professor David Owen

  • Doctor Philosophy

    Development of commercially viable cyclic peptide production for the protection of the Great Barrier Reef

    Principal Advisor

    Other advisors: Dr Conan Wang, Professor David Craik, Dr Thomas Durek

  • Doctor Philosophy

    Development of continuous downstream processing platform tools for implementation at a biologics contract development and manufacturing organization

    Principal Advisor

Completed supervision

Enquiries

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