
Overview
Background
Professor Khosrotehrani is a clinical scientist, dircetor of the Frazer institute, the university of Queensalnd, sharing his passion for academic medicine and translation of science discorveries into real world solutions for patients. Prof Khosrotehrani is a dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Frazer Institute within the Translational Research Institute in Brisbane, Australia. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.
As the inaugural St Baker-Soyer chair of Dermatology at the University of Queensland, Professor Khosrotehrani is a national leader in the discipline of Dermatology. He is a board director at the Australasian College of Dermatologists and the Queensland Skin and Cancer Foundation and the director of the Dermatology Department at the Princess Alexandra Hospital. He has held multiple leadership roles as past-President of the Australasian Society for Dermatology Research, Editor in chief of the Australasian Journal of Dermatology and board member of the International Society of investigative Dermatology.
During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Paris
Research interests
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Tissue regeneration
Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
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Skin cancer
Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation
Works
Search Professor Kiarash Khosrotehrani’s works on UQ eSpace
2011
Conference Publication
The immune response influences melanocyte proliferation after ultraviolet radiation exposure
Handoko, H. Y., Rodero, M., Walker, G. and Khosrotehrani, Ki (2011). The immune response influences melanocyte proliferation after ultraviolet radiation exposure. International Pigment Cell Conference (XXIst , IPCC, 2011), Bordeaux, France, 21-24 September 2011. Malden, MA, U.S.A.: Wiley-Blackwell Publishing. doi: 10.1111/j.1755-148X.2011.00885.x
2011
Conference Publication
Characterisation and control of macrophage recruitment during skin wound healing by systemic CX3CR1 antagonism (F1)
Rodero, Mathieu, Dorgham, Karim, Hodgson, Samatha, Combadiere, Christophe and Khosrotehrani, Kiarash (2011). Characterisation and control of macrophage recruitment during skin wound healing by systemic CX3CR1 antagonism (F1). 41st Annual Meeting of the European Society for Dermatological Research, Barcelona, Spain, 7-10 September 2011.
2011
Conference Publication
Epidermal IGF-1 receptor is important in the maintenance of bulge stem cell and their response to skin wounds
Edwige, R., Linay, F, Holzenberger, M., Oster, M., Aractingi, S. and Khosrotehrani, K. (2011). Epidermal IGF-1 receptor is important in the maintenance of bulge stem cell and their response to skin wounds. Annual Meeting of the Society for Investigative Dermatology, Phoenix, Arizona, United States, 4 – 7 May 2011.
2011
Conference Publication
Epidermal IGF-1 receptor is important in the maintenance of bulge stem cells, hair follicle cycle and response to skin wounds
Roy, E, Linay, F, Holzenberger, M, Oster, M, Aractingi, S and Khosrotehrani, K (2011). Epidermal IGF-1 receptor is important in the maintenance of bulge stem cells, hair follicle cycle and response to skin wounds. 41st Annual Meeting of the European-Society-for-Dermatological-Research, Barcelona Spain, Sep 07-10, 2011.
2011
Conference Publication
Does fetal microchimerism confer a protective role against melanoma in women?
Leveque, Lucie, Rodero, Mathieu, Fisk, Nicholas and Khosrotehrani, Kiarash (2011). Does fetal microchimerism confer a protective role against melanoma in women?. 41st Annual Meeting of the European Society for Dermatological Research, Barcelona, Spain, 7-10 September 2011. London, United Kingdom: Nature Publishing Group. doi: 10.1038/jid.2011.214
2011
Conference Publication
In vivo Quantitative Monitoring of Hair Cycle Dynamics in Mice During Pregnancy and Lactation
Hodgson, Samantha and Khosrotehrani, Kiarash (2011). In vivo Quantitative Monitoring of Hair Cycle Dynamics in Mice During Pregnancy and Lactation. 41st Annual Meeting of the European Society for Dermatological Research, Barcelona, Spain, 7-10 September 2011.
2011
Conference Publication
Mouse models to investigate stem cells in skin homeostasis and wounds
Khosrotehrani, K. (2011). Mouse models to investigate stem cells in skin homeostasis and wounds. 38th Annual Meeting of the Society for Cutaneous Ultrastructure Research, Brisbane, Australia, 30-31 May 2011. Oxford, England, U. K.: Wiley-Blackwell Publishing. doi: 10.1111/j.1600-0625.2011.01352.x
2011
Conference Publication
Macrophages influence melanocyte proliferation after ultraviolet radiation exposure
Rodero, Mathieu, Handoko, Herlina, Walker, Graeme and Khosrotehrani, Kiarash (2011). Macrophages influence melanocyte proliferation after ultraviolet radiation exposure. Annual Meeting of the European Society for Dermatological Research (41st, ESDR, 2011), Barcelona, Spain, 7-10 September 2011. London, Hamps, U.K.: Nature Publishing Group. doi: 10.1038/jid.2011.214
2010
Journal Article
Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis
Ferguson, Blake, Muller, H. Konrad, Handoko, Herlina Y., Khosrotehrani, Kiarash, Beermann, Friedrich, Hacker, Elke, Soyer, H. Peter, Bosenberg, Marcus and Walker, Graeme J. (2010). Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis. Pigment Cell and Melanoma Research, 23 (6), 771-780. doi: 10.1111/j.1755-148X.2010.00752.x
2010
Journal Article
Fetal stem cell microchimerism: natural-born healers or killers?
Lee, Eddy S. M., Bou-Gharios, George, Seppanen, Elke, Khosrotehrani, Kiarash and Fisk, Nicholas M. (2010). Fetal stem cell microchimerism: natural-born healers or killers?. Molecular Human Reproduction, 16 (11) gaq067, 869-878. doi: 10.1093/molehr/gaq067
2010
Journal Article
Limited functional capacity of microchimeric fetal hematopoietic progenitors acquired by mothers during pregnancy
Leduc, Michele, Guegan, Sarah, Roy, Edwige, Oster, Michele, Aractingi, Selim and Khosrotehrani, Kiarash (2010). Limited functional capacity of microchimeric fetal hematopoietic progenitors acquired by mothers during pregnancy. Experimental Hematology, 38 (10), 852-853. doi: 10.1016/j.exphem.2010.06.009
2010
Journal Article
Lichen plan buccal erosif associe a un syndrome de Good [Oral erosive lichen planus associated with Good syndrome]
Blanchard, M., Méneret, A., Moguelet, P., Brian, E., Baron, M., Khosrotehrani, K., Bazelly, B. and Bachmeyer, C. (2010). Lichen plan buccal erosif associe a un syndrome de Good [Oral erosive lichen planus associated with Good syndrome]. La Revue de Médecine Interne, 31 (7), 498-501. doi: 10.1016/j.revmed.2009.12.010
2010
Journal Article
Painful cutaneous nodules in a 57-year-old woman with human immunodeficiency virus infection Disseminated Mycobacterium avium infection with cutaneous abscesses in a patient with HIV and immune reconstitution inflammatory syndrome (IRIS)
Chakvetadze, C., Lamontagne, F., Khosrotehrani, K., Bani-Sadr, F., Caby, F., Lescure, F. -X., Moguelet, P. and Pialoux, G. (2010). Painful cutaneous nodules in a 57-year-old woman with human immunodeficiency virus infection Disseminated Mycobacterium avium infection with cutaneous abscesses in a patient with HIV and immune reconstitution inflammatory syndrome (IRIS). Clinical and Experimental Dermatology, 35 (3), 333-334. doi: 10.1111/j.1365-2230.2009.03256.x
2010
Conference Publication
Calpain activity is essential for cell recruitment, myofibroblast differentiation and angiogenesis in early stages of skin wounding
Nassar, D., Letavernier, E., Baud, L., Aractingi, S. and Khosrotehrani, K. (2010). Calpain activity is essential for cell recruitment, myofibroblast differentiation and angiogenesis in early stages of skin wounding. 40th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR 2010), Helsinki FINLAND, SEP 08-11, 2010.
2010
Conference Publication
Calpain activity is essential for cell recruitment, myofibroblast differentiation and angiogenesis in early stages of skin wound
Nassar, D., Letavernier, E., Baud, L., Aractingi, S. and Khosrotehrani, K. (2010). Calpain activity is essential for cell recruitment, myofibroblast differentiation and angiogenesis in early stages of skin wound. Annual Meeting of the Society-for-Investigative-Dermatology, Atlanta GA, MAY 05-08, 2010.
2010
Journal Article
Skin wound healing modulation by macrophages
Rodero, Mathieu P. and Khosrotehrani, Kiarash (2010). Skin wound healing modulation by macrophages. International Journal of Clinical and Experimental Pathology, 3 (7), 643-653.
2010
Conference Publication
Melanoma growth and metastasis is dependent on the presence of vitronectin in the extracellular matrix
Mesnard, L., Prignon, A., Halabi, M., Guegan, S., Rondeau, E., Aractingi, A. and Khosrotehrani, K. (2010). Melanoma growth and metastasis is dependent on the presence of vitronectin in the extracellular matrix. Annual Meeting of the Society-for-Investigative-Dermatology, Atlanta GA, MAY 05-08, 2010.
2010
Conference Publication
CALPAIN INHIBITION AFFECTS GRANULATION TISSUE FORMATION AND RESULTS IN DELAYED WOUND HEALING
Nassar, D., Roy, E., Letavernier, E., Aractingi, S. and Khosrotehrani, K. (2010). CALPAIN INHIBITION AFFECTS GRANULATION TISSUE FORMATION AND RESULTS IN DELAYED WOUND HEALING. 2nd Australasian Wound and Tissue Repair Society (AWTRS) Meeting, Perth, Australia, 22-24 March 2010.
2009
Journal Article
Fetal cell microchimerism in cancer: a meaningful event
Khosrotehrani, Kiarash and Aractingi, Selim (2009). Fetal cell microchimerism in cancer: a meaningful event. Future Oncology, 5 (9), 1441-1448. doi: 10.2217/FON.09.111
2009
Journal Article
Manifestations cutanées associées aux maladies inflammatoires chroniques intestinales
Farhi, D., Cosnes, J., Aractingi, S. and Khosrotehrani, K. (2009). Manifestations cutanées associées aux maladies inflammatoires chroniques intestinales. Annales De Dermatologie Et De Venereologie, 136 (11), 826-827. doi: 10.1016/j.annder.2009.03.014
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Photography
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Spatial omics to characterize the clinicopathologic subsets of melanoma
Principal Advisor
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Doctor Philosophy
Predicting melanoma survival using advanced digital imaging technologies
Principal Advisor
Other advisors: Dr Quan Nguyen
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Doctor Philosophy
Understanding and targeting determinants of mortality from melanoma
Principal Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Evaluating the impact of social determinants of health on skin cancer outcomes
Principal Advisor
Other advisors: Dr Lea Dousset
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Master Philosophy
Evaluating the effects of chronic diseases and lifestyle on the risk of melanoma recurrence
Associate Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Understanding immune diversity in skin inflammation
Associate Advisor
Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee
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Master Philosophy
Antibody-mediated exacerbation of chronic wounds colonised with Pseudomonas aeruginosa
Associate Advisor
Other advisors: Associate Professor Timothy Wells
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Doctor Philosophy
Predictive and prognostic biomarkers for melanoma progression (BioMEL)
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
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Doctor Philosophy
Understanding Melanoma Vascularisation to prevent metastasis
Associate Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Characterizing the role of ion channel kinase in skin homeostasis
Associate Advisor
Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari
Completed supervision
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2024
Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2024
Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
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2024
Doctor Philosophy
Potency and activity of meso-endothelial bipotent progenitors in vivo in homeostasis and injury
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2024
Doctor Philosophy
Identifying genetic and epigenetic regulators of skin and hair follicle physiology and disease in mice: A systems-based approach using The Collaborative Cross
Principal Advisor
Other advisors: Dr Sally Mortlock
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2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Antje Blumenthal
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2023
Doctor Philosophy
Investigating the contribution of vascular Sox9 to fibrosis in homeostasis and systemic sclerosis
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Master Philosophy
Mutation burden as a biomarker of keratinocyte cancer risk prediction and field treatment efficacy
Principal Advisor
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2022
Doctor Philosophy
Defining endovascular progenitors in homeostasis and disease
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2022
Doctor Philosophy
Uncovering the Role of Endovascular Progenitors in Melanoma Development and Metastatic Progression
Principal Advisor
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2020
Master Philosophy
Predicting melanoma outcome using clinical and biological indicators
Principal Advisor
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2019
Master Philosophy
Dissecting Molecular Events in Pregnancy-Associated Melanoma
Principal Advisor
Other advisors: Associate Professor Helmut Schaider
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2018
Master Philosophy
Understanding the differences between basal cell carcinoma subtypes at the genomic and transcriptomic level.
Principal Advisor
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2018
Doctor Philosophy
The Role of Skin Macrophages Under Conditions of Stress and Injury: Ultraviolet Irradiation and Wound Healing
Principal Advisor
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2017
Doctor Philosophy
Prognostic factors in early stage invasive cutaneous melanoma
Principal Advisor
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2017
Doctor Philosophy
A Genome-wide Approach to Identify Genetic Determinants of Skin Wound Healing and Scar Formation.
Principal Advisor
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2015
Master Philosophy
The influence of pregnancy, parity, and sex on melanoma prognosis
Principal Advisor
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2015
Doctor Philosophy
Mesenchymal-Epidermal Interactions in Hair Follicle Cycling and Regeneration
Principal Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
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2018
Doctor Philosophy
The role of SOX7 transcription factor in early blood vessel development
Associate Advisor
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2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2013
Doctor Philosophy
Endogenous stem cell behaviour in tissue repair: lessons from fetal microchimerism
Associate Advisor
Media
Enquiries
Contact Professor Kiarash Khosrotehrani directly for media enquiries about:
- basal cell carcinoma
- Dermatology
- Fetal stem cells
- Melanoma
- Skin cancer
- Skin wound healing
- squamous cell carcinoma
- Stem cells - fetal
- Stem cells - skin wound healing
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