
Overview
Background
Professor Khosrotehrani is a clinical scientist, dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Diamantina Institute within the Translational Research Institute in Brisbane, Australia. He is also the deputy director of the Australian Skin and Skin Cancer Research Centre in Brisbane. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.
During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). He is currently a fellow of the NHMRC of Australia. The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Paris
Research interests
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Tissue regeneration
Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
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Skin cancer
Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation
Works
Search Professor Kiarash Khosrotehrani’s works on UQ eSpace
2009
Journal Article
CD34+cells in maternal placental blood are mainly fetal in origin and express endothelial markers
Parant, Olivier, Dubernard, Gil, Challier, Jean-Claude, Oster, Michele, Uzan, Serge, Aractingi, Selim and Khosrotehrani, Kiarash (2009). CD34+cells in maternal placental blood are mainly fetal in origin and express endothelial markers. Laboratory Investigation, 89 (8), 915-923. doi: 10.1038/labinvest.2009.55
2009
Journal Article
Neonatal cases of infantile myofibromatosis do not derive from maternal cells transferred during pregnancy
Yousefi, P, Khosrotehrani, Kiarash, Oster, Michele, De Prost, Yves, Fraitag, S and Aractingi, Selim (2009). Neonatal cases of infantile myofibromatosis do not derive from maternal cells transferred during pregnancy. British Journal of Dermatology, 160 (6), 1356-1357. doi: 10.1111/j.1365-2133.2009.09135.x
2009
Journal Article
Gestational microchimerism in human diseases [Microchimérisme postgestationnel en pathologie humaine]
Parant, Olivier, Khosrotehrani, Kiarash and Aractingi, Selim (2009). Gestational microchimerism in human diseases [Microchimérisme postgestationnel en pathologie humaine]. La Presse Medicale, 38 (4), 584-590. doi: 10.1016/j.lpm.2008.05.020
2009
Journal Article
Two observations raising questions about risk factors of cutaneous necrosis induced by Terlipressin (Glypressin (R))
Megarbane, Hala, Barete, Stephane, Khosrotehrani, Kiarash, Izzedine, Hassan, Moguelet, Phillippe, Chosidow, Olivier, Frances, Camille and Aractingi, Selim (2009). Two observations raising questions about risk factors of cutaneous necrosis induced by Terlipressin (Glypressin (R)). Dermatology, 218 (4), 334-337. doi: 10.1159/000195676
2009
Journal Article
Fetal microchimeric cells participate in tumour angiogenesis in melanomas occurring during pregnancy
Han, Sun Nguyen, Oster, Michele, Avril, Marie-Francoise, Boitier, Francoise, Mortier, Laurent, Richard, Marie-Aleth, Kerob, Delphine, Maubec, Eve, Souteyrand, Pierre, Moguelet, Philippe, Khosrotehrani, Kiarash and Aractingi, Selim (2009). Fetal microchimeric cells participate in tumour angiogenesis in melanomas occurring during pregnancy. American Journal of Pathology, 174 (2), 630-637. doi: 10.2353/ajpath.2009.080566
2009
Conference Publication
Fetal cells persist in chronic wounds, form blood vessels and enhance healing
Nassar, D., Droitcourt, C., Parant, O., Mathieu-d'Argent, E., Uzan, S., Khosrotehrani, K. and Aractingi, S. (2009). Fetal cells persist in chronic wounds, form blood vessels and enhance healing. Annual Congress of the French-Speaking Society for Dermatological Research, Reims, France, 3-5 June, 2009. Nature Publishing.
2009
Conference Publication
Pregnancy promotes melanoma lymph node invasion by enhancing VEGF dependent lymphangiogenesis
Khosrotehrani, Kiarash, Huu, Sau Nguyen, Prignon, A., Oster, Michele, Avril, M.F., Boitier, F. and Aractingi, Selim (2009). Pregnancy promotes melanoma lymph node invasion by enhancing VEGF dependent lymphangiogenesis. 39th Annual European Society for Dermatological Research Meeting, Budapest, Hungary, 9-12 September 2009. Baltimore, MD: Nature Publishing Gourp. doi: 10.1038/jid.2009.232
2009
Book Chapter
Fetal cell microchimerism: a low-grade naturally occurring cell therapy
Leduc, Michele, Aractingi, Selim and Khosrotehrani, Kiarash (2009). Fetal cell microchimerism: a low-grade naturally occurring cell therapy. Perinatal Stem Cells. (pp. 203-208) edited by Curtis L. Cetrulo, Kyle J. Cetrulo and Curtis L. Jr. Cetrulo. Hoboken NJ: John Wiley. doi: 10.1002/9780470480151.ch13
2009
Conference Publication
Fetal cells persist in maternal chronic wounds, form blood vessels and enhance healing
Nassar, D., Droitcourt, C., Parant, O., Mathieu-d'Argent, E., Oster, M., Uzan, S., Khosrotehrani, K. and Aractingi, S. (2009). Fetal cells persist in maternal chronic wounds, form blood vessels and enhance healing. 39th Annual European Society for Dermatological Research Meeting, Budapest, Hungary, 9-12 September 2009. Baltimore, MD: Nature Publishing. doi: 10.1038/jid.2009.232
2009
Book Chapter
Life threatening dermatoses during gestation
Khosrotehrani, Kiarash (2009). Life threatening dermatoses during gestation. Life-threatening dermatoses and emergencies in dermatology. (pp. 175-180) edited by Jean Revuz. Berlin: Springer. doi: 10.1007/978-3-540-79339-7_18
2008
Journal Article
Healing of sickle cell ulcers during pregnancy: A favourable effect of foetal cell transfer?
Droitcourt, C., Khosrotehrani, K., Girot, R. and Aractingi, S. (2008). Healing of sickle cell ulcers during pregnancy: A favourable effect of foetal cell transfer?. Journal of the European Academy of Dermatology and Venereology, 22 (10), 1256-1257. doi: 10.1111/j.1468-3083.2008.02602.x
2008
Journal Article
Early phase of maternal skin carcinogenesis recruits long-term engrafted fetal cells
Huu, Sau Nguyen, Khosrotehrani, Kiarash, Oster, Michele, Moguelet, Philippe, Espie, Marie-Josee and Aractingi, Selim (2008). Early phase of maternal skin carcinogenesis recruits long-term engrafted fetal cells. International Journal of Cancer, 123 (11), 2512-2517. doi: 10.1002/ijc.23819
2008
Journal Article
Significance of erythema nodosum and pyoderma gangrenosum in inflammatory bowel diseases: A cohort study of 2402 patients
Farhi, David, Cosnes, Jacques, Zizi, Nada, Chosidow, Olivier, Seksik, Philippe, Beaugerie, Laurent, Aractingi, Selim and Khosrotehrani, Kiarash (2008). Significance of erythema nodosum and pyoderma gangrenosum in inflammatory bowel diseases: A cohort study of 2402 patients. Medicine, 87 (5), 281-293. doi: 10.1097/MD.0b013e318187cc9c
2008
Journal Article
Age at diagnosis of neurofibromatosis 1: An audit of practice
Abecassis, S., Bastuji-Garin, S., Khosrotehrani, K., Zeller, J., Revuz, J. and Wolkenstein, P. (2008). Age at diagnosis of neurofibromatosis 1: An audit of practice. Dermatology, 216 (4), 347-348. doi: 10.1159/000116622
2008
Journal Article
Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers
Khosrotehrani, K., Leduc, M., Bachy, V., Hun, S. N., Oster, M., Abbas, A., Uzan, S. and Aractingi, S. (2008). Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers. Journal of Immunology, 180 (5), 3613-3613. doi: 10.4049/jimmunol.180.5.3613-a
2008
Journal Article
Breast cancer stroma frequently recruits fetal derived cells during pregnancy
Dubernard, Gil, Aractingi, Selim, Oster, Michele, Rouzier, Roman, Mathieu, Marie-Christine, Uzan, Serge and Khosrotehrani, Kiarash (2008). Breast cancer stroma frequently recruits fetal derived cells during pregnancy. Breast Cancer Research, 10 (1) R14, 1-8. doi: 10.1186/bcr1860
2008
Journal Article
Risk of breast cancer related to pregnancy
Lesieur, B., Vercambre, M., Dubernard, G., Khosrotehrani, K., Uzan, S., Aractingi, S. and Rouzier, R. (2008). Risk of breast cancer related to pregnancy. Journal de Gynecologie Obstetrique et Biologie de la Reproduction, 37 (1), 77-81. doi: 10.1016/j.jgyn.2007.10.004
2008
Journal Article
Neurofibromatosis 1: Analysis of the demand for prenatal diagnosis in a French cohort of 361 patients
Farhi, David, Bastuji-Garin, Sylvie, Khosrotehrani, Kiarash, Vidaud, Dominique, Bellane, Christine, Revuz, Jean and Wolkenstein, Pierre (2008). Neurofibromatosis 1: Analysis of the demand for prenatal diagnosis in a French cohort of 361 patients. American Journal of Medical Genetics Part A, 146A (2), 159-165. doi: 10.1002/ajmg.a.32066
2008
Journal Article
Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers
Khosrotehrani, Kiarash, Leduc, Michele, Bachy, Veronique, Huu, Sau Nguyen, Oster, Michele, Abbas, Aicha, Uzan, Serge and Aractingi, Selim (2008). Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers. Journal of Immunology, 180 (2), 889-897. doi: 10.4049/jimmunol.180.2.889
2008
Conference Publication
Recruitment of long term engrafted fetal microchimeric cells in chemically induced maternal skin carcinogenesis
Huu, S. N., Khosrotehrani, K, Oster, M. and Aractingi, S. (2008). Recruitment of long term engrafted fetal microchimeric cells in chemically induced maternal skin carcinogenesis. International Investigative Dermatology Meeting, Kyoto , Japan, 14-17 May, 2008. Cambridge, U.S.: NPG.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Evaluating the impact of social determinants of health on melanoma outcomes
Principal Advisor
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Doctor Philosophy
Predicting melanoma survival using advanced digital imaging technologies
Principal Advisor
Other advisors: Dr Quan Nguyen
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Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
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Doctor Philosophy
Evaluating the impact of social determinants of health on skin cancer outcomes
Principal Advisor
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Master Philosophy
Understanding the mechanisms for increased mortality risk for pregnancy-associated melanoma.
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Spatial omics to characterize the clinicopathologic subsets of melanoma
Principal Advisor
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Doctor Philosophy
Understanding and targeting determinants of mortality from melanoma
Principal Advisor
Other advisors: Dr Lena Von Schuckmann
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Master Philosophy
A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Photography
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Understanding Melanoma Vascularisation to prevent metastasis
Associate Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Predictive and prognostic biomarkers for melanoma progression (BioMEL)
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
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Doctor Philosophy
Understanding immune diversity in skin inflammation
Associate Advisor
Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari
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Master Philosophy
Evaluating the effects of chronic diseases and lifestyle on the risk of melanoma recurrence
Associate Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee
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Master Philosophy
Antibody mediated exacerbation of Pseudomonas aeruginosa infected chronic wounds
Associate Advisor
Other advisors: Associate Professor Timothy Wells
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Doctor Philosophy
Characterizing the role of ion channel kinase in skin homeostasis
Associate Advisor
Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari
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Master Philosophy
Antibody-mediated exacerbation of Pseudomonas aeruginosa infected chronic wounds
Associate Advisor
Other advisors: Associate Professor Timothy Wells
Completed supervision
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2024
Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2024
Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
-
2024
Doctor Philosophy
Identifying genetic and epigenetic regulators of skin and hair follicle physiology and disease in mice: A systems-based approach using The Collaborative Cross
Principal Advisor
Other advisors: Dr Sally Mortlock
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2024
Doctor Philosophy
Potency and activity of meso-endothelial bipotent progenitors in vivo in homeostasis and injury
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Antje Blumenthal
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2023
Doctor Philosophy
Investigating the contribution of vascular Sox9 to fibrosis in homeostasis and systemic sclerosis
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Master Philosophy
Mutation burden as a biomarker of keratinocyte cancer risk prediction and field treatment efficacy
Principal Advisor
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2022
Doctor Philosophy
Defining endovascular progenitors in homeostasis and disease
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2022
Doctor Philosophy
Uncovering the Role of Endovascular Progenitors in Melanoma Development and Metastatic Progression
Principal Advisor
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2020
Master Philosophy
Predicting melanoma outcome using clinical and biological indicators
Principal Advisor
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2019
Master Philosophy
Dissecting Molecular Events in Pregnancy-Associated Melanoma
Principal Advisor
Other advisors: Associate Professor Helmut Schaider
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2018
Master Philosophy
Understanding the differences between basal cell carcinoma subtypes at the genomic and transcriptomic level.
Principal Advisor
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2018
Doctor Philosophy
The Role of Skin Macrophages Under Conditions of Stress and Injury: Ultraviolet Irradiation and Wound Healing
Principal Advisor
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2017
Doctor Philosophy
Prognostic factors in early stage invasive cutaneous melanoma
Principal Advisor
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2017
Doctor Philosophy
A Genome-wide Approach to Identify Genetic Determinants of Skin Wound Healing and Scar Formation.
Principal Advisor
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2015
Master Philosophy
The influence of pregnancy, parity, and sex on melanoma prognosis
Principal Advisor
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2015
Doctor Philosophy
Mesenchymal-Epidermal Interactions in Hair Follicle Cycling and Regeneration
Principal Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
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2018
Doctor Philosophy
The role of SOX7 transcription factor in early blood vessel development
Associate Advisor
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2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2013
Doctor Philosophy
Endogenous stem cell behaviour in tissue repair: lessons from fetal microchimerism
Associate Advisor
Media
Enquiries
Contact Professor Kiarash Khosrotehrani directly for media enquiries about:
- basal cell carcinoma
- Dermatology
- Fetal stem cells
- Melanoma
- Skin cancer
- Skin wound healing
- squamous cell carcinoma
- Stem cells - fetal
- Stem cells - skin wound healing
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