
Overview
Background
Professor Khosrotehrani is a clinical scientist, dircetor of the Frazer institute, the university of Queensalnd, sharing his passion for academic medicine and translation of science discorveries into real world solutions for patients. Prof Khosrotehrani is a dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Frazer Institute within the Translational Research Institute in Brisbane, Australia. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.
As the inaugural St Baker-Soyer chair of Dermatology at the University of Queensland, Professor Khosrotehrani is a national leader in the discipline of Dermatology. He is a board director at the Australasian College of Dermatologists and the Queensland Skin and Cancer Foundation and the director of the Dermatology Department at the Princess Alexandra Hospital. He has held multiple leadership roles as past-President of the Australasian Society for Dermatology Research, Editor in chief of the Australasian Journal of Dermatology and board member of the International Society of investigative Dermatology.
During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Paris
Research interests
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Tissue regeneration
Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
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Skin cancer
Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation
Works
Search Professor Kiarash Khosrotehrani’s works on UQ eSpace
2008
Journal Article
Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers
Khosrotehrani, K., Leduc, M., Bachy, V., Hun, S. N., Oster, M., Abbas, A., Uzan, S. and Aractingi, S. (2008). Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers. Journal of Immunology, 180 (5), 3613-3613. doi: 10.4049/jimmunol.180.5.3613-a
2008
Journal Article
Breast cancer stroma frequently recruits fetal derived cells during pregnancy
Dubernard, Gil, Aractingi, Selim, Oster, Michele, Rouzier, Roman, Mathieu, Marie-Christine, Uzan, Serge and Khosrotehrani, Kiarash (2008). Breast cancer stroma frequently recruits fetal derived cells during pregnancy. Breast Cancer Research, 10 (1) R14, 1-8. doi: 10.1186/bcr1860
2008
Journal Article
Risk of breast cancer related to pregnancy
Lesieur, B., Vercambre, M., Dubernard, G., Khosrotehrani, K., Uzan, S., Aractingi, S. and Rouzier, R. (2008). Risk of breast cancer related to pregnancy. Journal de Gynecologie Obstetrique et Biologie de la Reproduction, 37 (1), 77-81. doi: 10.1016/j.jgyn.2007.10.004
2008
Journal Article
Neurofibromatosis 1: Analysis of the demand for prenatal diagnosis in a French cohort of 361 patients
Farhi, David, Bastuji-Garin, Sylvie, Khosrotehrani, Kiarash, Vidaud, Dominique, Bellane, Christine, Revuz, Jean and Wolkenstein, Pierre (2008). Neurofibromatosis 1: Analysis of the demand for prenatal diagnosis in a French cohort of 361 patients. American Journal of Medical Genetics Part A, 146A (2), 159-165. doi: 10.1002/ajmg.a.32066
2008
Journal Article
Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers
Khosrotehrani, Kiarash, Leduc, Michele, Bachy, Veronique, Huu, Sau Nguyen, Oster, Michele, Abbas, Aicha, Uzan, Serge and Aractingi, Selim (2008). Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers. Journal of Immunology, 180 (2), 889-897. doi: 10.4049/jimmunol.180.2.889
2008
Conference Publication
Recruitment of long term engrafted fetal microchimeric cells in chemically induced maternal skin carcinogenesis
Huu, S. N., Khosrotehrani, K, Oster, M. and Aractingi, S. (2008). Recruitment of long term engrafted fetal microchimeric cells in chemically induced maternal skin carcinogenesis. International Investigative Dermatology Meeting, Kyoto , Japan, 14-17 May, 2008. Cambridge, U.S.: NPG.
2008
Conference Publication
Pregnancy does not result in enhanced angiogenesis in cutaneous inflammation and wound healing
Aractingi, S., Parant, O., Huu, S. N., Oster, M. and Khosrotehrani, K. (2008). Pregnancy does not result in enhanced angiogenesis in cutaneous inflammation and wound healing. International Investigative Dermatology Meeting, Kyoto, Japan, 14-17 May, 2008. Cambridge, U.S.: Nature Publishing.
2008
Journal Article
Cellulitis due to Myroides odoratimimus in a patient with alcoholic cirrhosis
Bachmeyer, C., Entressengle, H., Khosrotehrani, K., Goldman, G., Delisle, F., Arlet, G. and Grateau, G. (2008). Cellulitis due to Myroides odoratimimus in a patient with alcoholic cirrhosis. Clinical and Experimental Dermatology, 33 (1), 97-98. doi: 10.1111/j.1365-2230.2007.02590.x
2008
Conference Publication
Induction of psoriasis-like lesions after unrelated cord blood transplantation following non-myeloablative conditioning
Rio, B., Bachmeyer, C., Moguelet, P., Khosrotehrani, K., Lapusan, S., Marie, J. P. and Aractingi, S. (2008). Induction of psoriasis-like lesions after unrelated cord blood transplantation following non-myeloablative conditioning. 34th Annual Meeting of the European Group for Blood and Marrow Transplantation; 24nd Meeting of the EBMT Nurses-Group; 7th Meeting of the EBMT Data Management Group, Florence, Italy, 30 March -2 April, 2008. Basingstoke, England: Nature Publishing Group.
2007
Journal Article
Misleading pustular plaques of the lower limbs during Crohn's disease: Two case reports
Farhi, David, Duriez, Paul, Aractingi, Selim, Cosnes, Jacques and Khosrotehrani, Kiarash (2007). Misleading pustular plaques of the lower limbs during Crohn's disease: Two case reports. Journal of Medical Case Reports, 1 (1) 109. doi: 10.1186/1752-1947-1-109
2007
Journal Article
Spot counting to locate fetal cells in maternal blood and tissue: A comparison of manual and automated microscopy
Johnson, Kirby L., Stroh, Helene, Khosrotehrani, K and Bianchi, Diana W. (2007). Spot counting to locate fetal cells in maternal blood and tissue: A comparison of manual and automated microscopy. Microscopy Research and Technique, 70 (7), 585-588. doi: 10.1002/jemt.20439
2007
Journal Article
Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease
de Fonclare, Anne-Laure, Khosrotehrani, Kiarash, Aractingi, Selim, Duriez, Paul, Cosnes, Jacques and Beaugerie, Laurent (2007). Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease. Archives of Dermatology, 143 (6), 744-748. doi: 10.1001/archderm.143.6.744
2007
Journal Article
Idiopathic recurrent palmoplantar hidradenitis: a case with late onset and long-lasting course
Kluger, N., Moguelet, P., Khosrotehrani, K. and Aractingi, S. (2007). Idiopathic recurrent palmoplantar hidradenitis: a case with late onset and long-lasting course. Clinical and Experimental Dermatology, 32 (2), 217-218. doi: 10.1111/j.1365-2230.2006.02350.x
2007
Journal Article
Fetal cells participate over time in the response to specific types of murine maternal hepatic injury
Khosrotehrani, Kiarash, Reyes, R.R., Johnson, K.L., Freeman, R.B., Salomon, R.N., Peter, I., Stroh, Helene, Guegan, S. and Bianchi, Diana W. (2007). Fetal cells participate over time in the response to specific types of murine maternal hepatic injury. Human Reproduction, 22 (3), 654-661. doi: 10.1093/humrep/del426
2007
Journal Article
Primary cutaneous follicular B-cell lymphoma arising at the site of radiotherapy for breast cancer
Bachmeyer, C., Khosrotehrani, K., Moguelet, P. and Aractingi, S. (2007). Primary cutaneous follicular B-cell lymphoma arising at the site of radiotherapy for breast cancer. British Journal of Dermatology, 156 (1), 198-199. doi: 10.1111/j.1365-2133.2006.07600.x
2007
Journal Article
Acute myelogenous leukemia in a patient receiving etanercept for psoriasis
Bachmeyer, Claude, Thioliere, Brigitte, Khosrotehrani, Kiarash and Cattan, Elie (2007). Acute myelogenous leukemia in a patient receiving etanercept for psoriasis. Journal of the American Academy of Dermatology, 56 (1), 169-170. doi: 10.1016/j.jaad.2006.06.032
2007
Conference Publication
Enhanced maternal and fetal derived angiogenesis in melanomas during pregnancy
Nguyen-Huu, S., Aractingi, S., Oster, M. and Khosrotehrani, K. (2007). Enhanced maternal and fetal derived angiogenesis in melanomas during pregnancy. 37th Annual Meeting of the European Society for DermatologicalResearch, Zurich, Switzerland, 5-8 September, 2007. Baltimore, U.S.: NPG.
2007
Conference Publication
Placental cells increase angiogenesis during skin wound healing
Khosrotehrani, K., Droitcourt, C., Mathieu, E., Oster, M. and Aractingi, S. (2007). Placental cells increase angiogenesis during skin wound healing. 37th Annual Meeting of the European Society for Dermatological Research Meeting, Zurich, Switzerland, September 5-8 2007. Baltimore, MD: Nature Publishing. doi: 10.1038/sj.jid.5701090
2006
Journal Article
Feto-maternal cell trafficking: A transfer of pregnancy associated progenitor cells
Huu, Sau Nguyen, Dubernard, Gil, Aractingi, Selim and Khosrotehrani, Kiarash (2006). Feto-maternal cell trafficking: A transfer of pregnancy associated progenitor cells. Stem Cell Reviews, 2 (2), 111-116. doi: 10.1385/SCR:2:2:111
2006
Journal Article
Presence of chimeric maternally derived keratinocytes in cutaneous inflammatory diseases of children: The example of pityriasis Lichenoides
Khosrotehrani, Kiarash, Guegan, Sarah, Fraitag, Sylvie, Oster, Michele, de Prost, Yves, Bodemer, Christine and Aractingi, Selim (2006). Presence of chimeric maternally derived keratinocytes in cutaneous inflammatory diseases of children: The example of pityriasis Lichenoides. Journal of Investigative Dermatology, 126 (2), 345-348. doi: 10.1038/sj.jid.5700060
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Photography
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Spatial omics to characterize the clinicopathologic subsets of melanoma
Principal Advisor
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Doctor Philosophy
Predicting melanoma survival using advanced digital imaging technologies
Principal Advisor
Other advisors: Dr Quan Nguyen
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Doctor Philosophy
Understanding and targeting determinants of mortality from melanoma
Principal Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Evaluating the impact of social determinants of health on skin cancer outcomes
Principal Advisor
Other advisors: Dr Lea Dousset
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Master Philosophy
Evaluating the effects of chronic diseases and lifestyle on the risk of melanoma recurrence
Associate Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Understanding immune diversity in skin inflammation
Associate Advisor
Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee
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Master Philosophy
Antibody-mediated exacerbation of chronic wounds colonised with Pseudomonas aeruginosa
Associate Advisor
Other advisors: Associate Professor Timothy Wells
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Doctor Philosophy
Predictive and prognostic biomarkers for melanoma progression (BioMEL)
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
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Doctor Philosophy
Understanding Melanoma Vascularisation to prevent metastasis
Associate Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Characterizing the role of ion channel kinase in skin homeostasis
Associate Advisor
Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari
Completed supervision
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2024
Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2024
Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
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2024
Doctor Philosophy
Identifying genetic and epigenetic regulators of skin and hair follicle physiology and disease in mice: A systems-based approach using The Collaborative Cross
Principal Advisor
Other advisors: Dr Sally Mortlock
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2024
Doctor Philosophy
Potency and activity of meso-endothelial bipotent progenitors in vivo in homeostasis and injury
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Antje Blumenthal
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2023
Doctor Philosophy
Investigating the contribution of vascular Sox9 to fibrosis in homeostasis and systemic sclerosis
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Master Philosophy
Mutation burden as a biomarker of keratinocyte cancer risk prediction and field treatment efficacy
Principal Advisor
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2022
Doctor Philosophy
Defining endovascular progenitors in homeostasis and disease
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2022
Doctor Philosophy
Uncovering the Role of Endovascular Progenitors in Melanoma Development and Metastatic Progression
Principal Advisor
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2020
Master Philosophy
Predicting melanoma outcome using clinical and biological indicators
Principal Advisor
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2019
Master Philosophy
Dissecting Molecular Events in Pregnancy-Associated Melanoma
Principal Advisor
Other advisors: Associate Professor Helmut Schaider
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2018
Master Philosophy
Understanding the differences between basal cell carcinoma subtypes at the genomic and transcriptomic level.
Principal Advisor
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2018
Doctor Philosophy
The Role of Skin Macrophages Under Conditions of Stress and Injury: Ultraviolet Irradiation and Wound Healing
Principal Advisor
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2017
Doctor Philosophy
Prognostic factors in early stage invasive cutaneous melanoma
Principal Advisor
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2017
Doctor Philosophy
A Genome-wide Approach to Identify Genetic Determinants of Skin Wound Healing and Scar Formation.
Principal Advisor
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2015
Master Philosophy
The influence of pregnancy, parity, and sex on melanoma prognosis
Principal Advisor
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2015
Doctor Philosophy
Mesenchymal-Epidermal Interactions in Hair Follicle Cycling and Regeneration
Principal Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
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2018
Doctor Philosophy
The role of SOX7 transcription factor in early blood vessel development
Associate Advisor
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2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2013
Doctor Philosophy
Endogenous stem cell behaviour in tissue repair: lessons from fetal microchimerism
Associate Advisor
Media
Enquiries
Contact Professor Kiarash Khosrotehrani directly for media enquiries about:
- basal cell carcinoma
- Dermatology
- Fetal stem cells
- Melanoma
- Skin cancer
- Skin wound healing
- squamous cell carcinoma
- Stem cells - fetal
- Stem cells - skin wound healing
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