Overview
Availability
- Associate Professor Jason Lee is:
- Available for supervision
Works
Search Professor Jason Lee’s works on UQ eSpace
2023
Journal Article
A molecular signature for IL-10-producing Th1 cells in protozoan parasitic diseases
Edwards, Chelsea L., Engel, Jessica A., De Labastida Rivera, Fabian, Ng, Susanna S., Corvino, Dillon, Montes de Oca, Marcela, Frame, Teija C.M., Chauhan, Shashi Bhushan, Singh, Siddharth Sanker, Kumar, Awnish, Wang, Yulin, Na, Jinrui, Mukhopadhyay, Pamela, Lee, Jason S., Nylén, Susanne, Sundar, Shyam, Kumar, Rajiv and Engwerda, Christian R. (2023). A molecular signature for IL-10-producing Th1 cells in protozoan parasitic diseases. JCI Insight, 8 (24) e169362, 1-17. doi: 10.1172/jci.insight.169362
2023
Journal Article
COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis
Hancock, Janelle L., Kalimutho, Murugan, Straube, Jasmin, Lim, Malcolm, Gresshoff, Irma, Saunus, Jodi M., Lee, Jason S., Lakhani, Sunil R., Simpson, Kaylene J., Bush, Ashley I., Anderson, Robin L. and Khanna, Kum Kum (2023). COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis. Journal of Experimental and Clinical Cancer Research, 42 (1) 90, 1-16. doi: 10.1186/s13046-023-02663-8
2023
Journal Article
IL-10-producing Th1 cells possess a distinct molecular signature in malaria
Edwards, Chelsea L., Ng, Susanna S., de Labastida Rivera, Fabian, Corvino, Dillon, Engel, Jessica A., Montes de Oca, Marcela, Bukali, Luzia, Frame, Teija C.M., Bunn, Patrick T., Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H., Loughland, Jessica R., Soon, Megan S.F., Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T., Johnston, Rebecca L., Lee, Jason S., Kuns, Rachel, Zhang, Ping, Boyle, Michelle J., Hill, Geoffrey R., McCarthy, James S., Kumar, Rajiv and Engwerda, Christian R. (2023). IL-10-producing Th1 cells possess a distinct molecular signature in malaria. Journal of Clinical Investigation, 133 (1) e153733. doi: 10.1172/jci153733
2022
Journal Article
Combined inhibition of G9a and EZH2 suppresses tumor growth via synergistic induction of IL24-mediated apoptosis
Casciello, Francesco, Kelly, Gregory M., Ramarao-Milne, Priya, Kamal, Nabilah, Stewart, Teneale A., Mukhopadhyay, Pamela, Kazakoff, Stephen H., Miranda, Mariska, Kim, Dorim, Davis, Felicity M., Hayward, Nicholas K., Vertino, Paula M., Waddell, Nicola, Gannon, Frank and Lee, Jason S. (2022). Combined inhibition of G9a and EZH2 suppresses tumor growth via synergistic induction of IL24-mediated apoptosis. Cancer Research, 82 (7), 1208-1221. doi: 10.1158/0008-5472.can-21-2218
2021
Journal Article
G9a inhibition enhances checkpoint inhibitor blockade response in melanoma
Kelly, Gregory M., Al-Ejeh, Fares, McCuaig, Robert, Casciello, Francesco, Kamal, Nabilah Ahmad, Ferguson, Blake, Pritchard, Antonia L., Ali, Sayed, Silva, Ines P., Wilmott, James S., Long, Georgina V., Scolyer, Richard A., Rao, Sudha, Hayward, Nicholas K., Gannon, Frank and Lee, Jason S. (2021). G9a inhibition enhances checkpoint inhibitor blockade response in melanoma. Clinical Cancer Research, 27 (9), 2624-2635. doi: 10.1158/1078-0432.CCR-20-3463
2021
Journal Article
Genome instability and pressure on non-homologous end joining drives chemotherapy resistance via a DNA repair crisis switch in triple negative breast cancer
Wiegmans, Adrian P., Ward, Ambber, Ivanova, Ekaterina, Duijf, Pascal H. G., Adams, Mark N., Najib, Idris Mohd, Van Oosterhout, Romy, Sadowski, Martin C., Kelly, Greg, Morrical, Scott W., O’Byrne, Ken, Lee, Jason S. and Richard, Derek J. (2021). Genome instability and pressure on non-homologous end joining drives chemotherapy resistance via a DNA repair crisis switch in triple negative breast cancer. NAR Cancer, 3 (2) zcab041, zcab022. doi: 10.1093/narcan/zcab022
2021
Journal Article
Histone modifying enzymes in gynaecological cancers
Ramarao-Milne, Priya, Kondrashova, Olga, Barry, Sinead, Hooper, John D., Lee, Jason S. and Waddell, Nicola (2021). Histone modifying enzymes in gynaecological cancers. Cancers, 13 (4) 816, 1-21. doi: 10.3390/cancers13040816
2021
Journal Article
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, Daniel J., Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie H., Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis E., Adeli, Khosrow, Adolph, Timon E., Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat B., Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed N., Agrotis, Alexander, Aguilar, Patricia V., Ahmad, S. Tariq, Ahmed, Zubair M., Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus ... Tong, Chun-Kit (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17 (1), 1-382. doi: 10.1080/15548627.2020.1797280
2020
Journal Article
ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome
Cheong, Melody, Gartlan, Kate H., Lee, Jason S., Tey, Siok-Keen, Zhang, Ping, Kuns, Rachel D., Andoniou, Christopher E., Martins, Jose Paulo, Chang, Karshing, Sutton, Vivien R., Kelly, Greg, Varelias, Antiopi, Vuckovic, Slavica, Markey, Kate A., Boyle, Glen M., Smyth, Mark J., Engwerda, Christian R., MacDonald, Kelli P.A., Trapani, Joseph A., Degli-Esposti, Mariapia A., Koyama, Motoko and Hill, Geoffrey R. (2020). ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome. Cancer Immunology Research, 8 (8), 1085-1098. doi: 10.1158/2326-6066.cir-19-0653
2020
Journal Article
Chromatin interactome mapping at 139 independent breast cancer risk signals
Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lima, Luize G., Hillman, Kristine M., Kaufmann, Susanne, Tuano, Natasha, Hussein, Nehal, Ham, Sunyoung, Mukhopadhyay, Pamela, Kazakoff, Stephen, Lee, Jason S., Michailidou, Kyriaki, Barnes, Daniel R., Antoniou, Antonis C., Fachal, Laura, Dunning, Alison M., Easton, Douglas F., Waddell, Nicola, Rosenbluh, Joseph, Möller, Andreas, Chenevix-Trench, Georgia, French, Juliet D. and Edwards, Stacey L. (2020). Chromatin interactome mapping at 139 independent breast cancer risk signals. Genome Biology, 21 (1) 8, 8. doi: 10.1186/s13059-019-1877-y
2019
Journal Article
Molecular basis of distinct oestrogen responses in endometrial and breast cancer
Baxter, Eva, Windloch, Karolina, Kelly, Greg, Lee, Jason S., Gannon, Frank and Brennan, Donal (2019). Molecular basis of distinct oestrogen responses in endometrial and breast cancer. Endocrine-Related Cancer, 26 (1), 31-46. doi: 10.1530/ERC-17-0563
2018
Journal Article
Granulocytes are unresponsive to IL-6 due to an absence of gp130
Wilkinson, Andrew N., Gartlan, Kate H., Kelly, Greg, Samson, Luke D., Olver, Stuart D., Avery, Judy, Zomerdijk, Nienke, Tey, Siok-Keen, Lee, Jason S., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Granulocytes are unresponsive to IL-6 due to an absence of gp130. Journal of Immunology, 200 (9), 3547-3555. doi: 10.4049/jimmunol.1701191
2018
Journal Article
Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia
Bond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2018). Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia. Epigenetics, 13 (1), 40-48. doi: 10.1080/15592294.2017.1411446
2017
Journal Article
G9a in hypoxia: Linking tumor hypoxia and epigenetic regulation
Casciello, Francesco and Lee, Jason S. (2017). G9a in hypoxia: Linking tumor hypoxia and epigenetic regulation. Cell Cycle, 16 (21), 2001-2002. doi: 10.1080/15384101.2017.1377505
2017
Journal Article
Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells
Gao, Yulong, Souza-Fonseca-Guimaraes, Fernando, Bald, Tobias, Ng, Susanna S., Young, Arabella, Ngiow, Shin Foong, Rautela, Jai, Straube, Jasmin, Waddell, Nic, Blake, Stephen J., Yan, Juming, Bartholin, Laurent, Lee, Jason S., Vivier, Eric, Takeda, Kazuyoshi, Messaoudene, Meriem, Zitvogel-, Laurence, Teng, Michele W. L., Belz, Gabrielle T., Engwerda, Christian R., Huntington, Nicholas D., Nakamura, Kyohei, Hoelzel, Michael and Smyth, Mark J. (2017). Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nature Immunology, 18 (9), 1004-1015. doi: 10.1038/ni.3800
2017
Journal Article
G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis
Casciello, Francesco, Al-Ejeh, Fares, Kelly, Greg, Brennan, Donal J., Ngiow, Shin Foong, Young, Arabella, Stoll, Thomas, Windloch, Karolina, Hill, Michelle M., Smyth, Mark J., Gannon, Frank and Lee, Jason S. (2017). G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proceedings of the National Academy of Sciences, 114 (27), 7077-7082. doi: 10.1073/pnas.1618706114
2017
Journal Article
Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells
Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152
2016
Journal Article
Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
Ghoussaini, Maya, French, Juliet D., Michailidou, Kyriaki, Nord, Silje, Beesley, Jonathan, Canisus, Sander, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lee, Jason S., Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Milne, Roger L., Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Beckmann, Matthias W., Fletcher, Olivia, Johnson, Nichola, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara ... kConFab/AOCS Investigators (2016). Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. American Journal of Human Genetics, 99 (4), 903-911. doi: 10.1016/j.ajhg.2016.07.017
2016
Journal Article
Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity
Karunarathne, Deshapriya S., Horne-Debets, Joshua M., Huang, Johnny X., Faleiro, Rebecca, Leow, Chiuan Yee, Amante, Fiona, Watkins, Thomas S., Miles, John J., Dwyer, Patrick J., Stacey, Katryn J., Yarski, Michael, Poh, Chek Meng, Lee, Jason S., Cooper, Matthew A., Rénia, Laurent, Richard, Derek, McCarthy, James S., Sharpe, Arlene H. and Wykes, Michelle N. (2016). Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity. Immunity, 45 (2), 333-345. doi: 10.1016/j.immuni.2016.07.017
2016
Journal Article
Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant
Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex ... Chenevix-Trench, Georgia (2016). Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics, 98 (5), 830-842. doi: 10.1016/j.ajhg.2016.03.001
Supervision
Availability
- Associate Professor Jason Lee is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Harnessing Epigenetic Plasticity to Develop Effective Novel Therapeutic Strategies for Recurrent Melanoma
Principal Advisor
Other advisors: Dr Mitchell Stark
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Principal Advisor
Other advisors: Professor Nikolas Haass, Professor Kiarash Khosrotehrani, Dr Abbas Shafiee
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Doctor Philosophy
Circular RNAs as a novel biomarker for ovarian cancer
Principal Advisor
Other advisors: Dr Quan Nguyen
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Doctor Philosophy
Identification of Novel Therapeutic Targets in Rare Aggressive Brain Cancers
Associate Advisor
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Doctor Philosophy
Understanding the interplay of MITF, TFEB and CDK4/6 on lysosome activity in melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass
Completed supervision
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2021
Doctor Philosophy
Investigating Molecular Targets of the DNA Damage Response in Triple Negative Breast Cancer
Associate Advisor
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2020
Doctor Philosophy
Opportunities for epigenetic therapies in ovarian cancer
Associate Advisor
Other advisors: Honorary Professor John Hooper
Media
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