Professor Kiarash Khosrotehrani
Professor

Kiarash Khosrotehrani

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Phone: 
+61 7 344 37088

Background

Professor Khosrotehrani is a clinical scientist, dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Diamantina Institute within the Translational Research Institute in Brisbane, Australia. He is also the deputy director of the Australian Skin and Skin Cancer Research Centre in Brisbane. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.

During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). He is currently a fellow of the NHMRC of Australia. The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.

Availability

Professor Kiarash Khosrotehrani is:
Available for supervision
Media expert

Fields of research

Biomedical and Clinical Sciences Cancer genetics Clinical sciences Dermatology Medical biotechnology Oncology and carcinogenesis

Qualifications

  • Doctor of Philosophy, University of Paris

Research interests

  • Tissue regeneration

    Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.

  • Skin cancer

    Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation

Search Professor Kiarash Khosrotehrani’s works on UQ eSpace

350 works between 2001 and 2025
All (350) Journal Article (225) Book Chapter (8) Conference Publication (117)

341 - 350 of 350 works

2003

Journal Article

Clinical risk factors for mortality in patients with neurofibromatosis 1: a cohort study of 378 patients

Khosrotehrani, Kiarash, Bastuji-Garin, Sylvie, Zeller, Jacques, Revuz, Jean and Wolkenstein, Pierre (2003). Clinical risk factors for mortality in patients with neurofibromatosis 1: a cohort study of 378 patients. Archives of Dermatology, 139 (2), 187-191. doi: 10.1001/archderm.139.2.187

Clinical risk factors for mortality in patients with neurofibromatosis 1: a cohort study of 378 patients

2003

Journal Article

Combined FISH and immunolabeling on paraffin-embedded tissue sections for the study of microchimerism

Khosrotehrani, Kiarash, Stroh, Helene, Bianchi, Diana W. and Johnson, Kirby L. (2003). Combined FISH and immunolabeling on paraffin-embedded tissue sections for the study of microchimerism. Biotechniques, 34 (2), 242-244.

Combined FISH and immunolabeling on paraffin-embedded tissue sections for the study of microchimerism

2003

Conference Publication

Medical management of neurofibromatosis 1: A cross-sectional study of 383 patients

Drappier, Jean-Christophe, Khosrotehrani, Kiarash, Zeller, Jacques, Revuz, Jean and Wolkenstein, Pierre (2003). Medical management of neurofibromatosis 1: A cross-sectional study of 383 patients. Journées Dermatologiques de Paris, Paris, France, 5-8 December 2001. New York: Elsevier. doi: 10.1067/S0190-9622(03)01481-6

Medical management of neurofibromatosis 1: A cross-sectional study of 383 patients

2003

Conference Publication

The influence of fetal loss on the presence of fetal cell microchimerism: A systematic review

Bianchi, D. W., Khosrotehrani, K., Lau, J., Cha, D. H. and Johnson, K. (2003). The influence of fetal loss on the presence of fetal cell microchimerism: A systematic review. Annual Meeting of the American-Society-of-Human-Genetics, Los Angeles, U.S., 4-8 November, 2003. Cambridge, U.S.: Cell Press.

The influence of fetal loss on the presence of fetal cell microchimerism: A systematic review

2003

Conference Publication

Quality of abstracts in 3 clinical dermatology journals

Dupuy, Alain, Khosrotehrani, Kiarash, Lebbe, Celeste, Rybojad, Michel and Morel, Patrice (2003). Quality of abstracts in 3 clinical dermatology journals. 20th World Congress of Dermatology, Paris, France, 3 - 5 July 2002. Chicago: American Medical Association. doi: 10.1001/archderm.139.5.589

Quality of abstracts in 3 clinical dermatology journals

2002

Journal Article

Abstract quality assessment of articles from the Annales de Dermatologie

Khosrotehrani, K., Dupuy, A., Lebbe, C., Rybojad, M. and Morel, P. (2002). Abstract quality assessment of articles from the Annales de Dermatologie. Annales de Dermatologie et de Venereologie, 129 (11), 1271-1275.

Abstract quality assessment of articles from the Annales de Dermatologie

2002

Conference Publication

Immunofluorescence following FISH: application to microchimerism studies

Stroh, H. P., Khosrotehrani, K., Bianchi, D. W. and Johnson, K. L. (2002). Immunofluorescence following FISH: application to microchimerism studies. 52nd Annual Meeting of the American Society of Human Genetics, Baltimore, MA, United States, 15-19 October 2002. Cambridge, MA, United States: Cell Press.

Immunofluorescence following FISH: application to microchimerism studies

2001

Journal Article

HLA-G expression in atopic dermatitis

Khosrotehrani, Kiarash, Le Danff, Caroline, Reynaud-Mendel, Béatrix, Dubertret, Louis, Carosella, Edgardo D. and Aractingi, Sélim (2001). HLA-G expression in atopic dermatitis. Journal of Investigative Dermatology, 117 (3), 750-752. doi: 10.1046/j.0022-202x.2001.01487.x

HLA-G expression in atopic dermatitis

2001

Conference Publication

Characterization of HLA-G1,-G2,-G3, and-G4 isoforms transfected in a human melanoma cell line

Riteau, B., Moreau, P., Menier, C., Khalil-Daher, I., Khosrotehrani, K., Bras-Goncalves, R., Paul, P., Dausset, J., Rouas-Freiss, N. and Carosella, E. D. (2001). Characterization of HLA-G1,-G2,-G3, and-G4 isoforms transfected in a human melanoma cell line. 4th International Conference on New Trends in Clinical and Experimental Immunosuppression, Geneva, Switzerland, 17-20 February 2000. Philadelphia, PA, United States: Elsevier. doi: 10.1016/S0041-1345(01)02021-8

Characterization of HLA-G1,-G2,-G3, and-G4 isoforms transfected in a human melanoma cell line

2001

Conference Publication

Chimerism, graft tolerance and tumors Chimérisme, tolérance du greffon et tumeurs

Khosrotehrani, K. and Aractingi, S. (2001). Chimerism, graft tolerance and tumors Chimérisme, tolérance du greffon et tumeurs.

Chimerism, graft tolerance and tumors Chimérisme, tolérance du greffon et tumeurs

Current funding

  • 2025
    Post-doctoral fellowship support for oncodermatology
    PA Research Foundation
    Open grant
  • 2025 - 2027
    Targeting Prostaglandin D2 Pathway for Enhanced Therapy in Atopic Dermatitis
    NHMRC Development Grant
    Open grant
  • 2024 - 2025
    Efficacy and safety of cetuximab and prochlorperazine combined for solid organ transplant patients with advanced Cutaneous Squamous Cell Carcinoma: CetPro study
    Metro South Hospital and Health Service
    Open grant
  • 2024 - 2026
    Targeting endothelial trans-differentiation in vascular lesions ((NHMRC Ideas Grant) administered by The University of Sydney)
    University of Sydney
    Open grant
  • 2023 - 2026
    Molecular definition of cellular states in the vascular endothelium
    ARC Discovery Projects
    Open grant
  • 2022 - 2025
    PREDICT: PREcision DIagnostiCs for early melanoma detection using spaTial biology and AI-guided image analysis
    United States Congressionally Directed Medical Research Programs - Melanoma Research Program
    Open grant
  • 2022 - 2027
    The SiroSkin study: A multi-centre randomised double-blind placebo-controlled trial of 1% topical sirolimus in the chemoprevention of facial squamous cell carcinomas in solid organ... (Stream 7)
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2021 - 2025
    Long-term protection in the growth restricted newborn
    Cerebral Palsy Alliance
    Open grant

Past funding

  • 2024 - 2025
    Onco-Derm: a single site prospective analysis of skin microbiome as a predictor of toxicity in patients receiving immune checkpoint inhibitor therapy
    Microba Pty Ltd
    Open grant
  • 2022 - 2024
    Determining Causative Mechanisms of Hidradenitis Suppurativa (TRI LINC grant led by MSHHS)
    Metro South Hospital and Health Service
    Open grant
  • 2022 - 2023
    Manufacturing biological substitutes for wound healing and skin regeneration
    Metro North Hospital and Health Service
    Open grant
  • 2021 - 2024
    Advanced technological approach to predicting survival in patients diagnosed with locally invasive cutaneous melanoma
    Cancer Council Queensland
    Open grant
  • 2020 - 2023
    Reducing the burden of skin cancers through advanced chemoimmuno-prophylaxis
    Queensland Advancing Clinical Research Fellowship
    Open grant
  • 2020 - 2022
    Molecular Targets in Endovascular Progenitors to Inhibit Lung and Skin Fibrosis in Scleroderma
    United States Congressionally Directed Medical Research Programs - Peer Reviewed Medical Research Program
    Open grant
  • 2020 - 2024
    QSKIN: the burden of skin cancer (NHMRC CTCS administered by QIMR Berghofer)
    Queensland Institute of Medical Research
    Open grant
  • 2019 - 2021
    Volumetric Modulated Arc Therapy (VMAT) Irradiation in Skin Cancer Incidence Prevention: A randomised, open-label, single arm, phase II, controlled trial (the Trial)
    Genesis Care Cancer Care Research Pty Ltd
    Open grant
  • 2019 - 2022
    Potency and activity of Meso-Endothelial bipotent progenitors in vivo
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    Targeting the pre-metastatic vascular niche in melanoma using a novel molecular strategy
    NHMRC Project Grant
    Open grant
  • 2018 - 2019
    Systems Biology of the skin
    Queensland Institute of Medical Research
    Open grant
  • 2018 - 2020
    Improving brain outcomes in the growth restricted newborn using placental stem cell treatment
    Financial Markets Foundation for Children
    Open grant
  • 2018 - 2021
    Fighting epidermal skin cancers by targeting epidermal clones that accumulate mutations
    NHMRC Project Grant
    Open grant
  • 2018 - 2020
    Improved antigen-specific immunotherapy for cutaneous malignant melanoma
    Cancer Council Queensland
    Open grant
  • 2018 - 2021
    Stem cell treatment for neonatal hypoxic ischaemic encephalopathy
    NHMRC Project Grant
    Open grant
  • 2018
    Targeted and personalised early detection of melanoma using a 3D teledermatology network
    PA Research Foundation
    Open grant
  • 2017 - 2018
    Cutting-edge Imaging System for the Early Diagnosis of Face and Scalp Skin Cancer
    The Honda Foundation
    Open grant
  • 2017 - 2020
    Improving brain oxygen levels in babies using stem cell treatment
    The Children's Hospital Foundation
    Open grant
  • 2017 - 2019
    Melanoma environment and heterogeneity in therapy sensitivity and resistance - Khosrotehrani
    Meehan Bequest
    Open grant
  • 2017 - 2020
    Modulating skin regenerative responses to improve wound repair and fight carcinogenesis
    NHMRC Career Development Fellowship
    Open grant
  • 2017 - 2019
    Predictors of mortality in thin melanomas
    Cancer Council Queensland
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    The Australian human microbiota project-microbe isolation facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Translational dermatology in skin and skin cancer research
    UQ Fellowships
    Open grant
  • 2015 - 2017
    The natural history of skin cancer formation: from normal skin to cancer
    Leo Foundation
    Open grant
  • 2015 - 2018
    Preventing basal cell carcinoma formation by targeting the tumour environment
    Leo Foundation
    Open grant
  • 2015
    Laser doppler perfusion imaging (LDPI) of revascularisation sites following vascular stem cell therapy
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2015 - 2017
    Role of resident endothelial progenitor cells in melanoma vascularisation and progression
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    Systems analysis of epidermal biology and cancer (NHMRC Project Grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2014
    Anti-inflammatory strategies to promote healing of chronic diabetic wounds
    Diabetes Australia Research Trust
    Open grant
  • 2013 - 2014
    Targeting the dermal component of basal cell carcinoma
    Cancer Bequest Fund
    Open grant
  • 2013 - 2014
    A genome wide approach to identify important genetic determinants of skin wound healing
    Australasian College of Dermatologists Scientific Research Fund
    Open grant
  • 2013 - 2016
    Innovations in Diabetic Foot Ulcer (DFU) Wound Care (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2013
    Modelling mechanisms of drug responses in infantile haemangiomas (IH) by using placental endothelial progenitor cells (EPC)
    Australasian College of Dermatologists Scientific Research Fund
    Open grant
  • 2013 - 2015
    Tracking epidermal clonal evolution during skin cancer induction and progression
    NHMRC Project Grant
    Open grant
  • 2013 - 2014
    Understanding potency and role of individual stem cells in the skin using Rainbow technology
    ARC Discovery Projects
    Open grant
  • 2012 - 2014
    Fetal endothelial progenitors from the placenta as a source for cell therapy
    NHMRC Project Grant
    Open grant
  • 2012
    Multi-user in vivo and ex vivo tissue-level mechanical testing instrument for bone and stem cell research
    NHMRC Equipment Grant
    Open grant
  • 2012 - 2015
    NHMRC Career Development Fellowship (Clinical; Level 1): Stem and progenitor cell contribution to skin wounds and homeostasis
    NHMRC Career Development Award
    Open grant
  • 2012
    Tandem fluorescent and phase-contrast imaging of live cells in real time for application to cancer cell biology, developmental biology, respiratory biology, wound healing investigation and cellular to
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Routine assay to determine response to Braf inhibition therapy in melanoma
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2011 - 2012
    Role of maternofetal chimerism in transferring susceptibility to MS
    National Multiple Sclerosis Society-US
    Open grant
  • 2011 - 2013
    Development of the routine assay to determine response to Braf inhibition therapy in melanomas
    UQ FirstLink Scheme
    Open grant
  • 2011
    Molecular markers to predict sentinel lymph node invasion and 5-year and 10-year outcomes in patients with stage I and II primary melanoma
    Australasian College of Dermatologists Scientific Research Fund
    Open grant
  • 2011
    Persisting host dermal and epidermal antigen presenting cells as predictors of chronic graft versus host disease
    Australasian College of Dermatologists Scientific Research Fund
    Open grant
  • 2011
    Predictive value of STAT5 activity in melanoma metastasis and survival
    Royal Brisbane and Women's Hospital
    Open grant
  • 2010
    Macroscopic fluorescence imaging system for identifying and isolating transgenically tagged cells
    NHMRC Equipment Grant
    Open grant
  • 2010
    Multi-user small animal digital x-ray imaging machine for bone, cancer, inflammation and stem cell research
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2013
    Preclinical optimisation of intrauterine transplantation of fetal mesenchymal stem cells for osteogenesis imperfecta.
    NHMRC Project Grant
    Open grant
  • 2009 - 2010
    Influence of dermal fibroblasts on epidermal stem cell homeostasis in a model of ageing
    Ramaciotti Foundation
    Open grant
  • 2009
    High-end optical in vivo molecular imaging system for stem cells, tumours, tissue repair and pathogens
    UQ School/Centre Co-Funding
    Open grant

Availability

Professor Kiarash Khosrotehrani is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Evaluating the impact of social determinants of health on skin cancer outcomes

    Principal Advisor

  • Master Philosophy

    A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Photography

    Principal Advisor

    Other advisors: Ms Laura Sormani Le Bourhis

  • Master Philosophy

    Evaluating the impact of social determinants of health on melanoma outcomes

    Principal Advisor

  • Doctor Philosophy

    Predicting melanoma survival using advanced digital imaging technologies

    Principal Advisor

    Other advisors: Dr Quan Nguyen

  • Master Philosophy

    Spatial omics to characterize the clinicopathologic subsets of melanoma

    Principal Advisor

  • Master Philosophy

    Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma

    Principal Advisor

  • Doctor Philosophy

    Understanding and targeting determinants of mortality from melanoma

    Principal Advisor

    Other advisors: Dr Lena Von Schuckmann

  • Doctor Philosophy

    Mechanisms of Vascular Remodelling in Melanoma

    Principal Advisor

    Other advisors: Ms Laura Sormani Le Bourhis

  • Master Philosophy

    Understanding the mechanisms for increased mortality risk for pregnancy-associated melanoma.

    Principal Advisor

    Other advisors: Ms Laura Sormani Le Bourhis

  • Doctor Philosophy

    Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma

    Associate Advisor

    Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee

  • Doctor Philosophy

    Characterizing the role of ion channel kinase in skin homeostasis

    Associate Advisor

    Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari

  • Master Philosophy

    Antibody-mediated exacerbation of Pseudomonas aeruginosa infected chronic wounds

    Associate Advisor

    Other advisors: Associate Professor Timothy Wells

  • Doctor Philosophy

    Understanding immune diversity in skin inflammation

    Associate Advisor

    Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari

  • Doctor Philosophy

    Understanding Melanoma Vascularisation to prevent metastasis

    Associate Advisor

    Other advisors: Ms Laura Sormani Le Bourhis

  • Master Philosophy

    Evaluating the effects of chronic diseases and lifestyle on the risk of melanoma recurrence

    Associate Advisor

    Other advisors: Dr Lena Von Schuckmann

  • Master Philosophy

    Antibody mediated exacerbation of Pseudomonas aeruginosa infected chronic wounds

    Associate Advisor

    Other advisors: Associate Professor Timothy Wells

  • Doctor Philosophy

    Predictive and prognostic biomarkers for melanoma progression (BioMEL)

    Associate Advisor

    Other advisors: Associate Professor Mitchell Stark

Completed supervision

Enquiries

Contact Professor Kiarash Khosrotehrani directly for media enquiries about:

  • basal cell carcinoma
  • Dermatology
  • Fetal stem cells
  • Melanoma
  • Skin cancer
  • Skin wound healing
  • squamous cell carcinoma
  • Stem cells - fetal
  • Stem cells - skin wound healing

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