
Overview
Background
Professor Khosrotehrani is a clinical scientist, dircetor of the Frazer institute, the university of Queensalnd, sharing his passion for academic medicine and translation of science discorveries into real world solutions for patients. Prof Khosrotehrani is a dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Frazer Institute within the Translational Research Institute in Brisbane, Australia. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.
As the inaugural St Baker-Soyer chair of Dermatology at the University of Queensland, Professor Khosrotehrani is a national leader in the discipline of Dermatology. He is a board director at the Australasian College of Dermatologists and the Queensland Skin and Cancer Foundation and the director of the Dermatology Department at the Princess Alexandra Hospital. He has held multiple leadership roles as past-President of the Australasian Society for Dermatology Research, Editor in chief of the Australasian Journal of Dermatology and board member of the International Society of investigative Dermatology.
During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Paris
Research interests
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Tissue regeneration
Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
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Skin cancer
Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation
Works
Search Professor Kiarash Khosrotehrani’s works on UQ eSpace
2006
Conference Publication
Presence of fetal endothelial cells in melanomas during pregnancy
Nguyen Huu, S, Aractingi, S., Oster, M., Boitier, F., Mortier, L., Avril, M. F. and Khosrotehrani, K. (2006). Presence of fetal endothelial cells in melanomas during pregnancy. 36th Annual Meeting of the European Society of Dermatology (ESDR), Paris, France, 6-7 September, 2006. Baltimore, U.S.: NPG.
2006
Conference Publication
Maternal skin inflammation during pregnancy recruits fetal endothelial and inflammatory cells
Nguyen, Huu S., Aractingi, S., Oster, M., Espie, M. J., Chareyre, F. and Khosrotehrani, K. (2006). Maternal skin inflammation during pregnancy recruits fetal endothelial and inflammatory cells. 36th Annual Meeting of the European Society of Dermatology Research Meeting, Paris, 7-9 September 2006. Baltimore, MD: Nature Publishing. doi: 10.1038/sj.jid.5700514
2006
Conference Publication
Maternal contact hypersensitivity reactions during pregnancy recruit fetal VEGFR2 expressing microchimeric cells
Nguyen, S. H., Aractingi, S., Oster, M. and Khosrotehrani, K. (2006). Maternal contact hypersensitivity reactions during pregnancy recruit fetal VEGFR2 expressing microchimeric cells. 67th Annual Meeting of the Society for Investigative Dermatology, Philadelphia, PA, U.S.A., 3-6 May 2006. Baltimore, MD, U.S.A.: Nature Publishing. doi: 10.1038/sj.jid.5700298
2005
Journal Article
The utility of an erythroblast scoring system and gender-independent short tandem repeat (STR) analysis for the detection of aneuploid fetal cells in maternal blood
Cha, Dong Hyun, Khosrotehrani, Kiarash, Bianchi, Diana W. and Johnson, Kirby L. (2005). The utility of an erythroblast scoring system and gender-independent short tandem repeat (STR) analysis for the detection of aneuploid fetal cells in maternal blood. Prenatal Diagnosis, 25 (7), 586-591. doi: 10.1002/pd.1199
2005
Journal Article
Natural history of fetal cell microchimerism during and following murine pregnancy
Khosrotehrani, K, Johnson, Kirby L., Guegan, Sarah, Stroh, Helene and Bianchi, Diana W. (2005). Natural history of fetal cell microchimerism during and following murine pregnancy. Journal of Reproductive Immunology, 66 (1), 1-12. doi: 10.1016/j.jri.2005.02.001
2005
Journal Article
Multi-lineage potential of fetal cells in maternal tissue: a legacy in reverse
Khosrotehrani, Kiarash and Bianchi, Diana W. (2005). Multi-lineage potential of fetal cells in maternal tissue: a legacy in reverse. Journal of Cell Science, 118 (8), 1559-1563. doi: 10.1242/jcs.02332
2005
Journal Article
Skin carcinoma arising from donor cells in a kidney transplant recipient
Aractingi, Selim, Kanitakis, Jean, Euvrard, Sylvie, Le Danff, C, Peguillet, Isabelle, Khosrotehrani, Kiarash, Lantz, Olivier and Carosella, Edgardo D. (2005). Skin carcinoma arising from donor cells in a kidney transplant recipient. Cancer Research, 65 (5), 1755-1760. doi: 10.1158/0008-5472.CAN-04-2783
2005
Journal Article
Microchimerism: Fears and hopes
Aractingi, Selim and Khosrotehrani, Kiarash (2005). Microchimerism: Fears and hopes. Dermatology, 210 (1), 1-2. doi: 10.1159/000081473
2005
Conference Publication
Presence de keratinocytes chimeriques d'origine maternelle dans l'epiderme lese de patients pediatriques atteints de pityriasis lichenoide
Guegan, Sarah, Khosrotehrani, Kiarash, Fraitag, Sylvie, Oster, Michele, De Prost, Yves, Aractingi, Selim and Bodemer, Christine (2005). Presence de keratinocytes chimeriques d'origine maternelle dans l'epiderme lese de patients pediatriques atteints de pityriasis lichenoide. Journees Dermatolgiques de Paris, Paris, France, 6-10 December 2005. Paris, France: Masson.
2005
Journal Article
Subcutaneous neurofibromas are associated with mortality in neurofibromatosis 1: A cohort study of 703 patients
Khosrotehrani, Kiarash, Bastuji-Garin, Sylvie, Riccardi, Vincent M., Birch, Patricia, Friedman, Jan M. and Wolkenstein, Pierre (2005). Subcutaneous neurofibromas are associated with mortality in neurofibromatosis 1: A cohort study of 703 patients. American Journal of Medical Genetics Part A, 132A (1), 49-53. doi: 10.1002/ajmg.a.30394
2005
Conference Publication
Facteurs predictifs d'aggravation et de developpement d'une neoplasie chez le enfants atteints de neurofibromatose de type 1: suivi d'une cohorte pediatrique de 563 patients
Khosrotehrani, Kiarash, Bastuji-Garin, Sylvie, Farhi, David, Birch, P., Friedman, J.M. and Wolkenstein, Pierre (2005). Facteurs predictifs d'aggravation et de developpement d'une neoplasie chez le enfants atteints de neurofibromatose de type 1: suivi d'une cohorte pediatrique de 563 patients. Journees Dermatolgiques de Paris, Paris, France, 6-10 December 2005. Paris. France: Masson.
2005
Journal Article
Absence of fetal cell microchimerism in cutaneous lesions of lupus erythematosus
Khosrotehrani, K., Mery, L., Aractingi, S., Bianchi, D. W. and Johnson, K. L. (2005). Absence of fetal cell microchimerism in cutaneous lesions of lupus erythematosus. Annals of the Rheumatic Diseases, 64 (1), 159-160. doi: 10.1136/ard.2003.020297
2005
Conference Publication
Recrutement des cellules foetales aux sites de dermite de contact survenant sur la peau maternelle pendant la grossesse
Nguyen, Huu S., Arcatingi, Selim, Oster, M., Chareyre, Fabrice and Khosrotehrani, Kiarash (2005). Recrutement des cellules foetales aux sites de dermite de contact survenant sur la peau maternelle pendant la grossesse. Journees Dermatolgiques de Paris, Paris, France, 6-10 December 2005. France: Masson.
2004
Journal Article
Fetal cell-free DNA circulates in the plasma of pregnant mice: relevance for animal models of fetomaternal trafficking
Khosrotehrani, Kiarash, Wataganara, Tuangsit, Bianchi, Diana W. and Johnson, Kirby L. (2004). Fetal cell-free DNA circulates in the plasma of pregnant mice: relevance for animal models of fetomaternal trafficking. Human Reproduction, 19 (11), 2460-2464. doi: 10.1093/humrep/deh445
2004
Journal Article
Fetal microchimeric cells and breast cancer: Reply
Johnson, K. L., Khosrotehrani, K., Cha, D. H., Salomon, R. N. and Bianchi, D. W. (2004). Fetal microchimeric cells and breast cancer: Reply. JAMA: Journal of the American Medical Association, 292 (13), 1552-1553. doi: 10.1001/jama.292.13.1552-b
2004
Journal Article
Elective pregnancy termination and microchimerism: Comment on the article by Khosrotehrani et al.
Khosrotehrani, K., Johnson, K. L. and Bianchi, D. W. (2004). Elective pregnancy termination and microchimerism: Comment on the article by Khosrotehrani et al.. Arthritis and Rheumatism, 50 (9), 3059-3059. doi: 10.1002/art.20651
2004
Conference Publication
Facteurs predictifs de mortalite au cours de la neurofibromatose 1: Etude d'une cohorte de 703 cas
Khosrotehrani, K., Bastuji-Garin, S., Riccardi, V., Birch, P. and Wolkenstein, P. (2004). Facteurs predictifs de mortalite au cours de la neurofibromatose 1: Etude d'une cohorte de 703 cas. Journees Dermatolgiques de Paris, Paris, 7-11 December 2004. Paris: Societe Francaise de Dermatologie.
2004
Conference Publication
Application of an erythroblast scoring system and DNA polymorphism sequence analysis for the gender-independent assessment of fetal cells in maternal blood
Cha, D., Khosrotehrani, K., Bianchi, D. and Johnson, K. (2004). Application of an erythroblast scoring system and DNA polymorphism sequence analysis for the gender-independent assessment of fetal cells in maternal blood. 25th Annual Meeting of the Society-for-Maternal-Fetal-Medicine, Reno, U.S., 9-12 February, 2005. St. Louis, U.S.: Mosby. doi: 10.1016/j.ajog.2004.10.038
2004
Conference Publication
Pregnancy associated progenitor cells (PAPCS): Natural history and response to maternal injury
Khosrotehrani, K., Johnson, K. L., Freeman, R., Stroh, H., Salomon, R. S., Guegan, S. and Bianchi, D. W. (2004). Pregnancy associated progenitor cells (PAPCS): Natural history and response to maternal injury. 2nd Annual Meeting of the International Society for Stem Cell Research, Boston, MA, 10-13 June 2004. Deerfield, Ill.: ISSCR.
2004
Conference Publication
Pregnancy-associated progenitor cells (PAPCs): A physiologically-acquired novel fetal stem cell?
Bianchi, D. W., Khosrotehrani, K., Freeman, R. and Johnson, K. L. (2004). Pregnancy-associated progenitor cells (PAPCs): A physiologically-acquired novel fetal stem cell?. Keystone Symposium on Molecular and Cellular Biology: Stem Cells (B2), Keystone, Colorado, 23-29 January 2004.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Evaluating the impact of social determinants of health on skin cancer outcomes
Principal Advisor
Other advisors: Dr Lea Dousset
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Master Philosophy
A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Photography
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Spatial omics to characterize the clinicopathologic subsets of melanoma
Principal Advisor
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Doctor Philosophy
Predicting melanoma survival using advanced digital imaging technologies
Principal Advisor
Other advisors: Dr Quan Nguyen
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Doctor Philosophy
Understanding and targeting determinants of mortality from melanoma
Principal Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee
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Master Philosophy
Antibody-mediated exacerbation of chronic wounds colonised with Pseudomonas aeruginosa
Associate Advisor
Other advisors: Associate Professor Timothy Wells
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Doctor Philosophy
Predictive and prognostic biomarkers for melanoma progression (BioMEL)
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
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Doctor Philosophy
Understanding Melanoma Vascularisation to prevent metastasis
Associate Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Characterizing the role of ion channel kinase in skin homeostasis
Associate Advisor
Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari
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Master Philosophy
Evaluating the effects of chronic diseases and lifestyle on the risk of melanoma recurrence
Associate Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Understanding immune diversity in skin inflammation
Associate Advisor
Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari
Completed supervision
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2024
Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2024
Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
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2024
Doctor Philosophy
Potency and activity of meso-endothelial bipotent progenitors in vivo in homeostasis and injury
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2024
Doctor Philosophy
Identifying genetic and epigenetic regulators of skin and hair follicle physiology and disease in mice: A systems-based approach using The Collaborative Cross
Principal Advisor
Other advisors: Dr Sally Mortlock
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2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Antje Blumenthal
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2023
Doctor Philosophy
Investigating the contribution of vascular Sox9 to fibrosis in homeostasis and systemic sclerosis
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Master Philosophy
Mutation burden as a biomarker of keratinocyte cancer risk prediction and field treatment efficacy
Principal Advisor
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2022
Doctor Philosophy
Defining endovascular progenitors in homeostasis and disease
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2022
Doctor Philosophy
Uncovering the Role of Endovascular Progenitors in Melanoma Development and Metastatic Progression
Principal Advisor
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2020
Master Philosophy
Predicting melanoma outcome using clinical and biological indicators
Principal Advisor
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2019
Master Philosophy
Dissecting Molecular Events in Pregnancy-Associated Melanoma
Principal Advisor
Other advisors: Associate Professor Helmut Schaider
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2018
Master Philosophy
Understanding the differences between basal cell carcinoma subtypes at the genomic and transcriptomic level.
Principal Advisor
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2018
Doctor Philosophy
The Role of Skin Macrophages Under Conditions of Stress and Injury: Ultraviolet Irradiation and Wound Healing
Principal Advisor
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2017
Doctor Philosophy
Prognostic factors in early stage invasive cutaneous melanoma
Principal Advisor
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2017
Doctor Philosophy
A Genome-wide Approach to Identify Genetic Determinants of Skin Wound Healing and Scar Formation.
Principal Advisor
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2015
Master Philosophy
The influence of pregnancy, parity, and sex on melanoma prognosis
Principal Advisor
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2015
Doctor Philosophy
Mesenchymal-Epidermal Interactions in Hair Follicle Cycling and Regeneration
Principal Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
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2018
Doctor Philosophy
The role of SOX7 transcription factor in early blood vessel development
Associate Advisor
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2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2013
Doctor Philosophy
Endogenous stem cell behaviour in tissue repair: lessons from fetal microchimerism
Associate Advisor
Media
Enquiries
Contact Professor Kiarash Khosrotehrani directly for media enquiries about:
- basal cell carcinoma
- Dermatology
- Fetal stem cells
- Melanoma
- Skin cancer
- Skin wound healing
- squamous cell carcinoma
- Stem cells - fetal
- Stem cells - skin wound healing
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