Overview
Background
Chiara is Professor in Veterinary Pathology at the School of Veterinary Science (SVS) of the University of Queensland (UQ). She is a board certified specialist veterinary pathologist (Diplomate of the European College of Veterinary Pathology), graduated with a DVM from the University of Teramo (Italy) in 2002 and a PhD in Ultrastructural Pathology in 2006. Before joining UQ in 2012, she has been working as an Assistant Professor in Veterinary Pathology at the University of Teramo (Italy). She has a specific research interest is small animal oncology, in particular canine prostate cancer, and veterinary oncoepidemiology. She is Chair of the canine prostate cancer subgroup at the Oncology Pathology Working Group (OPWG), co-coordinator of the Global Initiative for Veterinary Cancer Surveillance (GIVCS) committee for the establishment of international standards of veterinary cancer registration and team leader of the comparative oncology theme of the Queensland Alliance of One Health Science. She is also member of the board of the Veterinary Cancer Guidelines and Protocols (VCGP) group, member of the Oncology Committee of the World Small Animal Veterinary Association (WSAVA) and chair of the ESVP/ECVP DEI task force. She is past President of the Australian Society for Veterinary Pathology and, within UQ SVS, she has been postgraduate coursework coordinator (2014-2017), HDR coordinator (2017-2019) and Director of Research (2019-2021). She is now coordinator of the UQ SVS veterinary pathology postgraduate training program. She has received several academic awards, including SVS awards for research excellence (2017, 2021), best lecturer (2021, 2022, 2023, 2024), and UQ award for excellence in HDR supervision (2020). She has published more than 120 papers on international journals, 3 book chapters and numerous abstracts in proceedings of national and international conferences. She has > 15 years expertise in veterinary diagnostic pathology, histopathology, IHC and TEM in multiple species. Since her first academic appointment in 2005, she mentored several postgraduate and undergraduate students in diagnostic investigation of animal cancer and research in canine oncology. Although outside the field of comparative oncology, she also a unique expertise in avian pathology and transmission electron microscopy.
Availability
- Professor Chiara Palmieri is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours), unknown
- Doctor of Philosophy of Veterinary Medicine, unknown
- Advanced Diploma, unknown
Research interests
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Pathogenesis of prostate cancer in dog, used as animal model for the spontaneous disease in men
The work of my research group has had impact in terms of understanding the mechanisms leading to this highly malignant tumour and is attracting considerable global interest, through invited presentations, requests for collaborations and reviews. Under my leadership, canine prostate cancer subgroup of the Oncology Pathology Working Group has established the first international consensus on the classification of prostatic lesions and prostate cancer in dogs, now adopted by the international community of veterinary pathologists for diagnostic and research.
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Comparative oncology
Co-investigator on the successful application to the ACRF (Australian Cancer Research Foundation) for the establishment of a cutting-edge facility for Molecular Imaging agents in cancer in domestic animals at the Centre for Advanced Imaging (CAI). Studies on canine prostate cancer and canine osteosarcoma - invaluable models of human cancers.
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Avian pathology
Although outside the field of comparative oncology, I have a unique expertise in avian pathology, gained through a training placement at the California Animal Health and Food Safety Laboratories in Tulare (California) in 2009. Since then, I have been actively collaborating with Prof. HL Shivaprasad (UCDavis, California) on investigating infectious and non-infectious diseases of poultry, pet birds and wild birds, with 13 publications (> 100 total citations) and several conference presentations to date. My expertise in avian histopathology is also supporting the research portfolio of Prof Eugeni Roura (QAAFI) and his research team to study peri-hatching strategies to endure enteric pathogens in broilers, a 4-year grant funded by Agrifutures. This collaboration has led to the multi-institutional partnership for the development of a consortium on precision feeding in broiler chickens
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Veterinary cancer surveillance
• Since 2018, I am the Australian representative of the Global Initiative for Veterinary Cancer Surveillance (GIVCS), an international organisation aiming to standardise veterinary cancer coding and develop a veterinary cancer atlas as a reliable monitoring and surveillance tool for the development of cancer control plans and identification of risk factors. I am co-leading the development of the first guidelines for veterinary cancer registration that will be adopted worldwide to collect accurate and complete cancer data that can be used for cancer control and epidemiological research. • I am leading the development of a nationwide data asset of animal cancer data, the Australian Companion Animal Registry of Cancer (ACARCinom), funded by the Australian Research Data Commons (ARDC) in collaboration with veterinary pathologists, oncologists and epidemiologists from the University of Sydney, University of Adelaide, Murdoch University and James Cook University, as well as veterinary pathologists from the two major commercial veterinary pathology laboratories (Gribbles, Idexx).
Research impacts
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Invited speaker at The Pathology Grand Tour podcast (The Pathologist) available on Apple Podcasts and Spotify – topic: “Veterinary Pathology” 5: Veterinary Pathology (thepathologist.com)
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Mentioned in the UQ Research stories “Prostate cancer: not so secret’s men business” Prostate cancer: not so secret men's business (uq.edu.au)
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Interview for the Australian Research Data Commons (ARDC) website on the establishment of the Australian Companion Animal Registry of Cancer (ACARCinom) – First national dog and cat cancer database in the making:https://ardc.edu.au/news/first-national-dog-and-cat-cancer-database/ . Faculty of Science website: https://science.uq.edu.au/article/2021/08/first-national-dog-and-cat-cancer-database-making-0
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Interview for Veterinary Practice Magazine (June 2015) with cover [“International investigator – renowned veterinary pathologist, Associate Professor Chiara Palmieri, talks about her research and how it impacts the profession”] http://issuu.com/engagemedia/docs/vet_practice_june_2015/1?e=2154905/13402554
Works
Search Professor Chiara Palmieri’s works on UQ eSpace
2024
Journal Article
An ovine septic shock model of live bacterial infusion
Obonyo, Nchafatso G., Raman, Sainath, Suen, Jacky Y., Peters, Kate M., Phan, Minh-Duy, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Palmieri, Chiara, White, Nicole, Sato, Kei, Farah, Samia M., Gandini, Lucia, Liu, Keibun, Fior, Gabriele, Heinsar, Silver, Ijuin, Shinichi, Kyun Ro, Sun, Abbate, Gabriella, Ainola, Carmen, Sato, Noriko, Lundon, Brooke, Portatadino, Sofia, Rachakonda, Reema H., Schneider, Bailey, Harley, Amanda, See Hoe, Louise E., Schembri, Mark A. ... Fraser, John F. (2024). An ovine septic shock model of live bacterial infusion. Intensive Care Medicine Experimental, 12 (1) 94. doi: 10.1186/s40635-024-00684-x
2024
Journal Article
Pathology-Based Animal Cancer Registry of Abruzzo and Molise Regions (Central Italy): A Ten-Year Retrospective Study (2014–2023)
Di Teodoro, Giovanni, Cito, Francesca, Salini, Romolo, Baffoni, Marina, Defourny, Sabrina V. P., Cocco, Antonio, D’Alterio, Nicola, Palmieri, Chiara and Petrini, Antonio (2024). Pathology-Based Animal Cancer Registry of Abruzzo and Molise Regions (Central Italy): A Ten-Year Retrospective Study (2014–2023). Veterinary Sciences, 11 (11), 521. doi: 10.3390/vetsci11110521
2024
Journal Article
Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors
Sato, Kei, See Hoe, Louise, Chan, Jonathan, Obonyo, Nchafatso G., Wildi, Karin, Heinsar, Silver, Colombo, Sebastiano M., Ainola, Carmen, Abbate, Gabriella, Sato, Noriko, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Livingstone, Samantha, Haymet, Andrew, Jung, Jae‐Seung, Skeggs, Kris, Palmieri, Chiara, White, Nicole, Platts, David, Suen, Jacky Y., McGiffin, David C., Li Bassi, Gianluigi and Fraser, John F. (2024). Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors. European Journal of Clinical Investigation, 54 (10) e14259. doi: 10.1111/eci.14259
2024
Journal Article
Early-life immunomodulation by carvacrol delivered in ovo in broiler chickens
Meijer, Mila M.Y., Brand, Henry van den, Palmieri, Chiara, Niknafs, Shahram, Khaskheli, Asad A. and Roura, Eugeni (2024). Early-life immunomodulation by carvacrol delivered in ovo in broiler chickens. Poultry Science, 103 (12) 104286, 104286. doi: 10.1016/j.psj.2024.104286
2024
Journal Article
Antinociceptive and wound healing effects of a commercial formulation of lidocaine, bupivacaine, adrenaline and cetrimide applied topically to superficial skin wounds in horses
Pratt, Shaun, Sole-Guitart, Albert, de Klerk, Karla, Evans, Elizabeth, Hume, Jane, Palmieri, Chiara, Rainger, Joanne and Goodwin, Wendy (2024). Antinociceptive and wound healing effects of a commercial formulation of lidocaine, bupivacaine, adrenaline and cetrimide applied topically to superficial skin wounds in horses. Veterinary Record, 195 (3) e4395. doi: 10.1002/vetr.4395
2024
Conference Publication
Investigating the role of Koala Retrovirus in primary skeletal neoplasia in koalas
Chu, Carmen, McMichael, Lee, Palmieri, Chiara, Gordon, Jo, Meers, Joanne and Gonzalez Astudillo, Viviana (2024). Investigating the role of Koala Retrovirus in primary skeletal neoplasia in koalas. Australia and New Zealand College of Veterinary Scientists Science Week, Gold Coast, QLD Australia, 25-27 July 2024.
2024
Journal Article
Immunohistochemical characterization of the immune cell response during chlamydial infection in the male and female koala (Phascolarctos cinereus) reproductive tract
Pagliarani, Sara, Johnston, Stephen D., Beagley, Kenneth W. and Palmieri, Chiara (2024). Immunohistochemical characterization of the immune cell response during chlamydial infection in the male and female koala (Phascolarctos cinereus) reproductive tract. Veterinary Pathology, 61 (4), 621-632. doi: 10.1177/03009858231225499
2024
Journal Article
Bioactive metabolites of Asparagopsis stabilized in canola oil completely suppresses methane emissions in beef cattle fed a feedlot diet
Cowley, Frances C., Kinley, Robert D., Mackenzie, Sigrid L., Fortes, Marina R. S., Palmieri, Chiara, Simanungkalit, Gamaliel, Almeida, Amelia K. and Roque, Breanna M. (2024). Bioactive metabolites of Asparagopsis stabilized in canola oil completely suppresses methane emissions in beef cattle fed a feedlot diet. Journal of Animal Science, 102 skae109. doi: 10.1093/jas/skae109
2024
Journal Article
A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload
Sato, Kei, Wildi, Karin, Chan, Jonathan, Palmieri, Chiara, Obonyo, Nchafatso G., Heinsar, Silver, Liu, Keibun, Livingstone, Samantha, Sato, Noriko, Ainola, Carmen, Abbate, Gabriella, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Platts, David G., Suen, Jacky, Bassi, Gianluigi Li and Fraser, John F. (2024). A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload. European Journal of Clinical Investigation, 54 (2) e14106, 1-12. doi: 10.1111/eci.14106
2024
Journal Article
An appraisal of lung computer tomography in very early anti-inflammatory treatment of two different ovine ARDS phenotypes
Wildi, Karin, Colombo, Sebastiano Maria, McGuire, Daniel, Ainola, Carmen, Heinsar, Silver, Sato, Noriko, Sato, Kei, Liu, Keibun, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Livingstone, Samantha, Di Feliciantonio, Marianna, Strugnell, Wendy, Palmieri, Chiara, Suen, Jacky, Li Bassi, Gianluigi and Fraser, John (2024). An appraisal of lung computer tomography in very early anti-inflammatory treatment of two different ovine ARDS phenotypes. Scientific Reports, 14 (1) 2162, 1-11. doi: 10.1038/s41598-024-52698-w
2023
Journal Article
Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer
Wong, Kim, Abascal, Federico, Ludwig, Latasha, Aupperle-Lellbach, Heike, Grassinger, Julia, Wright, Colin W., Allison, Simon J., Pinder, Emma, Phillips, Roger M., Romero, Laura P., Gal, Arnon, Roady, Patrick J., Pires, Isabel, Guscetti, Franco, Munday, John S., Peleteiro, Maria C., Pinto, Carlos A., Carvalho, Tânia, Cota, João, Du Plessis, Elizabeth C., Constantino-Casas, Fernando, Plog, Stephanie, Moe, Lars, de Brot, Simone, Bemelmans, Ingrid, Amorim, Renée Laufer, Georgy, Smitha R., Prada, Justina, del Pozo, Jorge ... van der Weyden, Louise (2023). Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer. Genome Biology, 24 (1) 191. doi: 10.1186/s13059-023-03026-4
2023
Journal Article
Anatomy of the female koala reproductive tract
Pagliarani, Sara, Palmieri, Chiara, McGowan, Michael, Carrick, Frank, Boyd, Jackson and Johnston, Stephen D. (2023). Anatomy of the female koala reproductive tract. Biology, 12 (11) 1445, 1-34. doi: 10.3390/biology12111445
2023
Journal Article
Application of anti-inflammatory treatment in two different ovine Acute Respiratory Distress Syndrome injury models: a preclinical randomized intervention study
Wildi, Karin, Livingstone, Samantha, Ainola, Carmen, Colombo, Sebastiano Maria, Heinsar, Silver, Sato, Noriko, Sato, Kei, Bouquet, Mahé, Wilson, Emily, Abbate, Gabriella, Passmore, Margaret, Hyslop, Kieran, Liu, Keibun, Wang, Xiaomeng, Palmieri, Chiara, See Hoe, Louise E., Jung, Jae-Seung, Ki, Katrina, Mueller, Christian, Laffey, John, Pelosi, Paolo, Li Bassi, Gianluigi, Suen, Jacky and Fraser, John (2023). Application of anti-inflammatory treatment in two different ovine Acute Respiratory Distress Syndrome injury models: a preclinical randomized intervention study. Scientific Reports, 13 (1) 17986, 1-15. doi: 10.1038/s41598-023-45081-8
2023
Conference Publication
Geospatial co-distribution of human and canine urothelial cell carcinoma and associated environmental risk factors in Queensland, Australia
Owada, Kei, Palmieri, Chiara, Hu, Wenbiao, Gan, Ting, Knibbs, Luke D. and Soares Magalhães, Ricardo J. (2023). Geospatial co-distribution of human and canine urothelial cell carcinoma and associated environmental risk factors in Queensland, Australia. ISEE 2023: 35th Annual Conference of the International Society of Environmental Epidemiology, Kaohsiung, Taiwan, 17-21 September 2023. Research Triangle Park, NC United States: National Institute of Environmental Health Sciences. doi: 10.1289/isee.2023.op-015
2023
Journal Article
The koala (Phascolarctos cinereus) prostate: a comprehensive histological and immunohistochemical investigation
Campbell, Yolande, Palmieri, Chiara, Pagliarani, Sara, Gordon, Jo and Johnston, Stephen (2023). The koala (Phascolarctos cinereus) prostate: a comprehensive histological and immunohistochemical investigation. Biology of Reproduction, 109 (5), 644-653. doi: 10.1093/biolre/ioad098
2023
Journal Article
Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep
See Hoe, Louise E., Bassi, Gianluigi Li, Wildi, Karin, Passmore, Margaret R., Bouquet, Mahe, Sato, Kei, Heinsar, Silver, Ainola, Carmen, Bartnikowski, Nicole, Wilson, Emily S., Hyslop, Kieran, Skeggs, Kris, Obonyo, Nchafatso G., Shuker, Tristan, Bradbury, Lucy, Palmieri, Chiara, Pedersen, Sanne-Engkilde, McDonald, Charles, Colombo, Sebastiano M., Wells, Matthew A., Reid, Janice D., O'Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Haymet, Andrew, Jung, Jae-Seung, Sato, Noriko, James, Lynnette, He, Ting ... Fraser, John F. (2023). Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep. The Journal of Heart and Lung Transplantation, 42 (8), 1015-1029. doi: 10.1016/j.healun.2023.03.020
2023
Journal Article
Editorial: Precision medicine in veterinary oncology: volume II
Fonseca-Alves, Carlos Eduardo, Laufer-Amorim, Renée, Dagli, Maria Lucia Zaidan and Palmieri, Chiara (2023). Editorial: Precision medicine in veterinary oncology: volume II. Frontiers in Veterinary Science, 10 1219963. doi: 10.3389/fvets.2023.1219963
2023
Journal Article
Detection, characterization, and persistence of Campylobacter hepaticus, the cause of spotty liver disease in layer hens
Courtice, Jodi M., Ahmad, Tarek B., Wei, Chuanyu, Mahdi, Layla K., Palmieri, Chiara, Juma, Sarah, Groves, Peter J., Hancock, Kerry, Korolik, Victoria, Petrovsky, Nikolai and Kotiw, Michael (2023). Detection, characterization, and persistence of Campylobacter hepaticus, the cause of spotty liver disease in layer hens. Poultry Science, 102 (7) 102462, 1-7. doi: 10.1016/j.psj.2022.102462
2023
Journal Article
Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model
Tamang, Man Kumar, Ali, Asad, Pertile, Renata Nedel, Cui, Xiaoying, Alexander, Suzy, Nitert, Marloes Dekker, Palmieri, Chiara and Eyles, Darryl (2023). Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model. Translational Psychiatry, 13 (1) 204, 1-12. doi: 10.1038/s41398-023-02513-3
2023
Journal Article
Automated analysis of PD1 and PDL1 expression in lymph nodes and the microenvironment of transmissible tumors in Tasmanian devils
Russell, Grace G., Palmieri, Chiara, Darby, Jocelyn, Morris, Gary P., Fountain-Jones, Nicholas M., Pye, Ruth J. and Flies, Andrew S. (2023). Automated analysis of PD1 and PDL1 expression in lymph nodes and the microenvironment of transmissible tumors in Tasmanian devils. Immunological Investigations, 52 (6), 661-680. doi: 10.1080/08820139.2023.2217845
Funding
Current funding
Past funding
Supervision
Availability
- Professor Chiara Palmieri is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Veterinary Clinical Sci
Comparative oncology in companion animal models
Principal Advisor
Other advisors: Professor Rachel Allavena
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Master Philosophy
The secret killer: Unravelling the link between urban air pollutants and lung cancer in dogs
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Hatching out the secrets of female monotreme reproductive biology
Principal Advisor
Other advisors: Associate Professor Steve Johnston, Dr Taylor Pini
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Doctor Veterinary Clinical Sci
Innovative investigations on canine prostate cancer: evidence-based medicine, spatial modelling and artificial intelligence
Principal Advisor
Other advisors: Professor Ricardo Soares Magalhaes
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Doctor Philosophy
The role of cancer stem cells in the pathogenesis of preneoplastic and neoplastic prostatic lesions in dogs
Principal Advisor
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Doctor Philosophy
Comparing the clinical and histological changes seen in dogs treated with either an autologous anti-cancer vaccine or intra tumoral adjuvant.
Associate Advisor
Other advisors: Dr Lee McMichael, Professor Rachel Allavena
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Doctor Philosophy
Modulating early life immunity in broiler chickens through in ovo delivery of carvacrol
Associate Advisor
Other advisors: Dr Marta Navarro, Professor Eugeni Roura
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Doctor Philosophy
Peri-hatching strategies to endure enteric pathogens in broilers
Associate Advisor
Other advisors: Dr Marta Navarro, Professor Eugeni Roura
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Doctor Philosophy
Novel immunotherapeutics in the treatment of cancer in pet dogs: an investigation into the tumour microenvironment
Associate Advisor
Other advisors: Dr Lee McMichael, Dr Karen Jackson, Dr Solomon Woldeyohannes, Professor Rachel Allavena
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Doctor Philosophy
Program 1 of the Agrifutures Consortium on Chicken Nutrition, Gut Health, and Environment
Associate Advisor
Other advisors: Dr Marta Navarro, Dr Elham Assadi Soumeh, Dr Arun Kumar, Professor Eugeni Roura
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Doctor Philosophy
Investigation into stem cell markers as potential therapeutic vaccine targets for cancer treatment in dogs
Associate Advisor
Other advisors: Dr Lee McMichael, Professor Rachel Allavena
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Doctor Philosophy
Investigation into stem cell markers as potential therapeutic vaccine targets for cancer treatment in dogs
Associate Advisor
Other advisors: Dr Lee McMichael, Professor Rachel Allavena
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Doctor Philosophy
Dietary fibre and gut nutrient sensing in broiler chickens
Associate Advisor
Other advisors: Professor Eugeni Roura
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Doctor Philosophy
Comparative Anatomy and Physiology of Monotreme and Marsupial Accessory Glands
Associate Advisor
Other advisors: Associate Professor Steve Johnston, Dr Taylor Pini
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Master Philosophy
Vaccine based immunotherapy for osteosarcoma treatment in dogs
Associate Advisor
Other advisors: Professor Rachel Allavena
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Doctor Philosophy
Sustainable Precision Feeding in Broiler Chickens in Australia
Associate Advisor
Other advisors: Dr Noman Naseem, Professor Eugeni Roura
Completed supervision
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2023
Doctor Veterinary Clinical Sci
Splenic nodular lesions in dogs
Principal Advisor
Other advisors: Professor Rachel Allavena
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2021
Doctor Philosophy
Transcriptome signature of canine osteosarcoma and role of cytokines in the neoplastic growth
Principal Advisor
Other advisors: Professor Rachel Allavena, Dr Karen Jackson, Dr Aaron Herndon
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2021
Doctor Philosophy
Further insights into the pathogenesis of Chlamydiosis and characterisation of immune cells in the reproductive tract of koalas (Phascolarctos cinereus)
Principal Advisor
Other advisors: Associate Professor Steve Johnston
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2020
Master Philosophy
A STUDY OF VIRAL TISSUE TROPISM AND CYTOKINE EXPRESSION IN BOVINE EPHEMERAL FEVER
Principal Advisor
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2022
Doctor Veterinary Clinical Sci
The use of advanced diagnostic imaging modalities to reduce fetlock injury and breakdown in racing Thoroughbreds: a study of racehorse fatalities in South-East Queensland
Associate Advisor
Other advisors: Dr Solomon Woldeyohannes, Professor Ben Ahern
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2022
Doctor Philosophy
Investigation of porcine circovirus type 2 (PCV2) infection in pigs in the Philippines and Australia
Associate Advisor
Other advisors: Dr Conny Turni, Professor Joanne Meers
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2021
Doctor Veterinary Clinical Sci
Locking compression plate fixation for protection of the suspensory apparatus of the distal phalanx in cases of laminitis
Associate Advisor
Other advisors: Dr Steven Zedler, Dr Albert Sole Guitart, Professor Ben Ahern
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2021
Doctor Philosophy
The effect of Chlamydia on male koala (Phascolarctos cinereus) fertility
Associate Advisor
Other advisors: Associate Professor Steve Johnston
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2020
Doctor Philosophy
Pathological and clinicopathological features of canine and feline bladder disease
Associate Advisor
Other advisors: Dr Karen Jackson, Professor Rachel Allavena
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2019
Doctor Philosophy
Dietary manipulation of nutrient-specific appetites and feed particle size for improved growth uniformity in broilers
Associate Advisor
Other advisors: Professor Eugeni Roura
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2015
Master Philosophy
The mode of action of intra-dermal sodium lauryl sulfate (SLS) as a chemical alternative to mulesing in sheep
Associate Advisor
Media
Enquiries
Contact Professor Chiara Palmieri directly for media enquiries about:
- canine prostate cancer
- comparative oncology
- Veterinary cancer registration
- Veterinary cancer surveillance
- Veterinary Pathology
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