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Professor

Jean-Pierre Levesque

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Overview

Availability

Professor Jean-Pierre Levesque is:
Available for supervision

Works

Search Professor Jean-Pierre Levesque’s works on UQ eSpace

206 works between 1985 and 2024

21 - 40 of 206 works

2021

Journal Article

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

2020

Journal Article

Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils

Tseng, Hsu‐Wen, Kulina, Irina, Salga, Marjorie, Fleming, Whitney, Vaquette, Cedryck, Genêt, François, Levesque, Jean‐Pierre and Alexander, Kylie A (2020). Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils. Journal of Bone and Mineral Research, 35 (11) jbmr.4118, 2242-2251. doi: 10.1002/jbmr.4118

Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils

2020

Journal Article

When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification

Alexander, Kylie A., Tseng, Hsu-Wen, Salga, Marjorie, Genêt, François and Levesque, Jean-Pierre (2020). When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification. Current Osteoporosis Reports, 18 (6), 666-676. doi: 10.1007/s11914-020-00636-w

When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification

2020

Journal Article

Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G- CSF-, IL-1-, and TNF-independent manner

Bisht, Kavita, Tay, Joshua, Wellburn, Rebecca N., McGirr, Crystal, Fleming, Whitney, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G- CSF-, IL-1-, and TNF-independent manner. Frontiers in Immunology, 11 583550, 1-16. doi: 10.3389/fimmu.2020.583550

Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G- CSF-, IL-1-, and TNF-independent manner

2020

Conference Publication

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy, Millard, Susan, Batoon, Lena, Sandrock, Cheyenne, Levesque, Jean-Pierre, Hume, David, Raggatt, Liza and Pettit, Allison (2020). 3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice. 49th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, New York, NY USA, 20-23 August 2020. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.exphem.2020.09.105

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

2020

Journal Article

Acute myeloid leukemia chemo-resistance is mediated by E-selectin receptor CD162 in bone marrow niches

Erbani, Johanna, Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre and Winkler, Ingrid G. (2020). Acute myeloid leukemia chemo-resistance is mediated by E-selectin receptor CD162 in bone marrow niches. Frontiers in Cell and Developmental Biology, 8 668, 668. doi: 10.3389/fcell.2020.00668

Acute myeloid leukemia chemo-resistance is mediated by E-selectin receptor CD162 in bone marrow niches

2020

Journal Article

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

Barbier, Valerie, Erbani, Johanna, Fiveash, Corrine, Davies, Julie M., Tay, Joshua, Tallack, Michael R., Lowe, Jessica, Magnani, John L., Pattabiraman, Diwakar R., Perkins, Andrew C., Lisle, Jessica, Rasko, John E. J., Levesque, Jean-Pierre and Winkler, Ingrid G. (2020). Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nature Communications, 11 (1) 2042, 2042. doi: 10.1038/s41467-020-15817-5

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

2020

Journal Article

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

Tay, Joshua, Bisht, Kavita, McGirr, Crystal, Millard, Susan M., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow. Experimental Hematology, 82, 33-42. doi: 10.1016/j.exphem.2020.02.003

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

2020

Journal Article

CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains

Nowlan, Bianca, Williams, Elizabeth D., Doran, Michael R. and Levesque, Jean-Pierre (2020). CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains. Haematologica, 105 (1), 71-82. doi: 10.3324/haematol.2018.212910

CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains

2019

Conference Publication

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Erbani, Johanna D., Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre, Magnani, John L. and Winkler, Ingrid G. (2019). CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132233

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

2019

Conference Publication

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

Winkler, Ingrid G., Barbier, Valerie, Tay, Joshua, Levesque, Jean-Pierre, Magnani, John L., Fiveash, Corrine E. and Erbani, Johanna D. (2019). Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132212

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

2019

Journal Article

Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor

Bisht, Kavita, McGirr, Crystal, Alexander, Kylie A, Fleming, Whitney, Sims, Natalie, Newen, Gerhard Müller-, Winkler, Ingrid G and Levesque, Jean-Pierre (2019). Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor. Blood, 134 (Supplement_1), 4469-4469. doi: 10.1182/blood-2019-127431

Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor

2019

Journal Article

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2

Brennan, Faith H., Jogia, Trisha, Gillespie, Ellen R., Blomster, Linda V., Li, Xaria X., Nowlan, Bianca, Williams, Gail M., Jacobson, Esther, Osborne, Geoff W., Meunier, Frederic A., Taylor, Stephen M., Campbell, Kate E., MacDonald, Kelli P.A., Levesque, Jean-Pierre, Woodruff, Trent M. and Ruitenberg, Marc J. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI Insight, 4 (9) e98254. doi: 10.1172/jci.insight.98254

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2

2019

Journal Article

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

Alexander, Kylie A., Tseng, Hsu-Wen, Fleming, Whitney, Jose, Beulah, Salga, Marjorie, Kulina, Irina, Millard, Susan M., Pettit, Allison R., Genet, Francois and Levesque, Jean-Pierre (2019). Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. Frontiers in Immunology, 10 (MAR) 377. doi: 10.3389/fimmu.2019.00377

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

2019

Journal Article

HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

Bisht, Kavita, Brunck, Marion E., Matsumoto, Taichi, McGirr, Crystal, Nowlan, Bianca, Fleming, Whitney, Keech, Thomas, Magor, Graham, Perkins, Andrew C., Davies, Julie, Walkinshaw, Gail, Flippin, Lee, Winkler, Ingrid G. and Levesque, Jean-Pierre (2019). HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR. Blood Advances, 3 (3), 406-418. doi: 10.1182/bloodadvances.2018017566

HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

2019

Journal Article

Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice

Salga, Marjorie, Tseng, Hsu-Wen, Alexander, Kylie A., Jose, Beulah, Vaquette, Cedryck, Debaud, Charlotte, Gatin, Laure, Genêt, François and Levesque, Jean-Pierre (2019). Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice. Annals of Physical and Rehabilitation Medicine, 62 (3), 189-192. doi: 10.1016/j.rehab.2019.01.005

Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice

2018

Journal Article

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

2018

Conference Publication

Understanding hematopoietic stem/progenitor cell responses after spinal cord injury

Jung, Won-Cheol, Jogia, Trisha, Gillespie, Ellen, Reid, Chantelle, Levesque, Jean-Pierre and Ruitenberg, Marc (2018). Understanding hematopoietic stem/progenitor cell responses after spinal cord injury. 3rd Joint Symposium of the International-and-National-Neurotrauma-Societies-and-AANS/CNS-Section on Neurotrauma and Critical Care, Toronto, Canada, 11-16 August 2018. New Rochelle, NY, United States: Mary Ann Liebert.

Understanding hematopoietic stem/progenitor cell responses after spinal cord injury

2018

Conference Publication

Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture

Winkler, Ingrid G., Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Magnani, John L., Marlton, Paula, Mills, Anthony K., Perkins, Andrew, Fiveash, Corrine E., Erbani, Johanna M. and Levesque, Jean-Pierre (2018). Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-120376

Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture

2018

Conference Publication

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Funding

Current funding

  • 2020 - 2024
    Discovering the mechanisms of neurogenic heterotopic ossifications following spinal cord injuries
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2018 - 2020
    Colony-stimulating factor 1 receptor tyrosine kinase, a new target to treat acute myeloid leukemia
    Cancer Council Queensland
    Open grant
  • 2018 - 2020
    Increasing haematopoietic stem cell mobilisation by targeting a novel niche factor
    NHMRC Project Grant
    Open grant
  • 2018 - 2022
    Stem cell niches: Biology and therapeutic applications
    NHMRC Research Fellowship
    Open grant
  • 2017 - 2020
    Mechanisms by which Endothelial Selectins regulate Normal and Malignant Stem Cell fate
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Recipient bone marrow macrophages contribute to haematopoietic stem cell transplantation success
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Why macrophages promote heterotopic ossifications following spinal cord injuries
    NHMRC Project Grant
    Open grant
  • 2015 - 2019
    Mechanisms and Treatments of Heterotopic Ossification following Spinal Cord Injuries
    United States Congressionally Directed Medical Research Programs - Spinal Cord Injury Research Program
    Open grant
  • 2015 - 2017
    A preclinical humanized chimeric model to investigate novel therapeutic strategies against breast cancer bone metastasis (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2015 - 2018
    Haematopoietic Stem Cell glycome regulates outcome of niche interactions
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Targeting the hypoxia sensing pathway to improve hematopoietic stem cell mobilisation and transplantation
    NHMRC Project Grant
    Open grant
  • 2014 - 2015
    The role of macrophages in facilitating hematopoietic stem cell engraftment and reconstitution
    Cancer Council Queensland
    Open grant
  • 2013 - 2017
    NHMRC Research Fellowship: How does the bone marrow regulate normal blood formation and leukaemia progression.
    NHMRC Research Fellowship
    Open grant
  • 2013 - 2016
    Role of bone marrow cells in leukemia progression and resistance to chemotherapy
    NHMRC Project Grant
    Open grant
  • 2011 - 2012
    Comprehensive cell imaging facility (ARC LIEF Grant administered by QUT)
    ARC LIEF Collaborating/Partner Organisation Contributions
    Open grant
  • 2007 - 2012
    Interaction between PTH and Y2 bone anabolic pathways
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Jean-Pierre Levesque is:
Available for supervision

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Supervision history

Completed supervision

Media

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