Professor

Jean-Pierre Levesque

Email: 

Availability

Professor Jean-Pierre Levesque is:
Available for supervision

Search Professor Jean-Pierre Levesque’s works on UQ eSpace

221 works between 1985 and 2025
All (221) Journal Article (144) Conference Publication (71) Book Chapter (6)

61 - 80 of 221 works

2017

Journal Article

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

Batoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

2017

Journal Article

Peripheral denervation participates in heterotopic ossification in a spinal cord injury model

Debaud, Charlotte, Salga, Marjorie, Begot, Laurent, Holy, Xavier, Chedik, Malha, de l'Escalopier, Nicolas, Torossian, Frederic, Levesque, Jean-Pierre, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Genet, Francois (2017). Peripheral denervation participates in heterotopic ossification in a spinal cord injury model. PLoS One, 12 (8) e0182454, e0182454. doi: 10.1371/journal.pone.0182454

Peripheral denervation participates in heterotopic ossification in a spinal cord injury model

2017

Journal Article

HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice

Nowlan, Bianca, Futrega, Kathryn, Brunck, Marion, Walkinshaw, Gail, Flippin, Lee E., Doran, Michael R. and Levesque, Jean-Pierre (2017). HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice. Experimental Hematology, 52, 50-55. doi: 10.1016/j.exphem.2017.05.004

HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice

2017

Journal Article

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure C., Holzapfel, Boris M., McGovern, Jacqui A., Wagner, Ferdinand, Quent, Verena M., Hesami, Parisa, Wunner, Felix M., Vaquette, Cedryck, De-Juan-Pardo, Elena M., Brown, Toby D., Nowlan, Bianca, Wu, Dan Jing, Hutmacher, Cosmo Orlando, Moi, Davide, Oussenko, Tatiana, Piccinini, Elia, Zandstra, Peter W., Mazzieri, Roberta, Levesque, Jean-Pierre, Dalton, Paul D., Taubenberger, Anna V. and Hutmacher, Dietmar W. (2017). Engineering a humanized bone organ model in mice to study bone metastases. Nature Protocols, 12 (4), 639-663. doi: 10.1038/nprot.2017.002

Engineering a humanized bone organ model in mice to study bone metastases

2017

Journal Article

Cellular players of hematopoietic stem cell mobilization in the bone marrow niche

Tay, Joshua, Levesque, Jean‑Pierre and Winkler, Ingrid G. (2017). Cellular players of hematopoietic stem cell mobilization in the bone marrow niche. International Journal of Hematology, 105 (2), 129-140. doi: 10.1007/s12185-016-2162-4

Cellular players of hematopoietic stem cell mobilization in the bone marrow niche

2017

Journal Article

It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function

Jung, Won-Cheol, Levesque, Jean-Pierre and Ruitenberg, Marc J. (2017). It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function. Seminars in Cell and Developmental Biology, 61, 60-70. doi: 10.1016/j.semcdb.2016.08.010

It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function

2017

Book Chapter

The role of mesenchymal stem cells in hematopoiesis

Levesque, Jean-Pierre, Jacobsen, Rebecca N. and Winkler, Ingrid G. (2017). The role of mesenchymal stem cells in hematopoiesis. The biology and therapeutic application of mesenchymal cells. (pp. 467-480) edited by Kerry Atkinson. Hoboken, NJ, United States: John Wiley and Sons. doi: 10.1002/9781118907474.ch32

The role of mesenchymal stem cells in hematopoiesis

2016

Conference Publication

Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo

Goh, Sal Lee, Levesque, Jean-Pierre, Petitt, Allison R., Barbier, Valarie and Winkler, Ingrid G. (2016). Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo. 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 03-06, 2016. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V128.22.2835.2835

Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo

2016

Journal Article

Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedside

Levesque, Jean-Pierre and Winkler, Ingrid G. (2016). Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedside. Current Stem Cell Reports, 2 (4), 356-367. doi: 10.1007/s40778-016-0066-0

Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedside

2016

Conference Publication

Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo

Goh, Sal Lee, Levesque, Jean-Pierre, Pettit, Allison, Barbier, Valerie, Jeanclos, Cecile and Winkler, Ingrid (2016). Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier.

Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo

2016

Conference Publication

Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress

Tay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Barbier, Valerie, Nowlan, Bianca and Winkler, Ingrid (2016). Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.224

Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress

2016

Journal Article

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

Kaur, Simranpreet, Raggatt, Liza Jane, Batoon, Lena, Hume, David Arthur, Levesque, Jean-Pierre and Pettit, Allison Robyn (2016). Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches. Seminars in Cell and Developmental Biology, 61, 12-21. doi: 10.1016/j.semcdb.2016.08.009

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

2016

Journal Article

A validated preclinical animal model for primary bone tumor research

Wagner, Ferdinand, Holzapfel, Boris M., Thibaudeau, Laure, Straub, Melanie, Ling, Ming-Tat, Grifka, Joachim, Loessner, Daniela, Levesque, Jean-Pierre and Hutmacher, Dietmar W. (2016). A validated preclinical animal model for primary bone tumor research. The Journal of Bone and Joint Surgery, 98 (11), 916-925. doi: 10.2106/JBJS.15.00920

A validated preclinical animal model for primary bone tumor research

2016

Journal Article

CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

Wu, Andy C., He, Yaowu, Broomfield, Amy, Paatan, Nicoll J., Harrington, Brittney S., Tseng, Hsu-Wen, Beaven, Elizabeth A., Kiernan, Deirdre M., Swindle, Peter, Clubb, Adrian B., Levesque, Jean-Pierre, Winkler, Ingrid G., Ling, Ming-Tat, Srinivasan, Bhuvana, Hooper, John D. and Pettit, Allison R. (2016). CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer. Journal of Pathology, 239 (2), 218-230. doi: 10.1002/path.4718

CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

2016

Journal Article

Mobilization of hematopoietic stem cells with highest self-renewal by G-CSF precedes clonogenic cell mobilization peak

Winkler, Ingrid G., Wiercinska, Eliza, Barbier, Valerie, Nowlan, Bianca, Bonig, Halvard and Levesque, Jean-Pierre (2016). Mobilization of hematopoietic stem cells with highest self-renewal by G-CSF precedes clonogenic cell mobilization peak. Experimental Hematology, 44 (4), 303-314.e1. doi: 10.1016/j.exphem.2016.01.001

Mobilization of hematopoietic stem cells with highest self-renewal by G-CSF precedes clonogenic cell mobilization peak

2016

Journal Article

Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse

Jacobsen, Rebecca N., Nowlan, Bianca, Brunck, Marion E., Barbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Pierre (2016). Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse. Experimental Hematology, 44 (3), 207-212.e4. doi: 10.1016/j.exphem.2015.11.004

Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse

2016

Conference Publication

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

Levesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

2016

Conference Publication

Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors

Bisht, Kavita, Jacobsen, Rebecca, Nowlan, Bianca, McGirr, Crystal, Brunck, Marion, Keech, Thomas, Winkler, Ingrid G. and Levesque, Jean-Pierre (2016). Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V128.22.546.546

Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors

2016

Conference Publication

Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors

Bisht, Kavita, Jacobsen, Rebecca, Brunck, Marion, Keech, Thomas, McGirr, Crystal, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2016). Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors. 45th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.096

Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors

2016

Conference Publication

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

Kaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

Current funding

  • 2025 - 2028
    Mechanisms and first prophylactic treatments of neurogenic heterotopic ossifications
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2024
    Discovering the mechanisms of neurogenic heterotopic ossifications following spinal cord injuries
    NHMRC IDEAS Grants
    Open grant
  • 2018 - 2020
    Colony-stimulating factor 1 receptor tyrosine kinase, a new target to treat acute myeloid leukemia
    Cancer Council Queensland
    Open grant
  • 2018 - 2020
    Increasing haematopoietic stem cell mobilisation by targeting a novel niche factor
    NHMRC Project Grant
    Open grant
  • 2018 - 2022
    Stem cell niches: Biology and therapeutic applications
    NHMRC Research Fellowship
    Open grant
  • 2017 - 2020
    Mechanisms by which Endothelial Selectins regulate Normal and Malignant Stem Cell fate
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Recipient bone marrow macrophages contribute to haematopoietic stem cell transplantation success
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Why macrophages promote heterotopic ossifications following spinal cord injuries
    NHMRC Project Grant
    Open grant
  • 2015 - 2019
    Mechanisms and Treatments of Heterotopic Ossification following Spinal Cord Injuries
    United States Congressionally Directed Medical Research Programs - Spinal Cord Injury Research Program
    Open grant
  • 2015 - 2017
    A preclinical humanized chimeric model to investigate novel therapeutic strategies against breast cancer bone metastasis (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2015 - 2018
    Haematopoietic Stem Cell glycome regulates outcome of niche interactions
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Targeting the hypoxia sensing pathway to improve hematopoietic stem cell mobilisation and transplantation
    NHMRC Project Grant
    Open grant
  • 2014 - 2015
    The role of macrophages in facilitating hematopoietic stem cell engraftment and reconstitution
    Cancer Council Queensland
    Open grant
  • 2013 - 2017
    NHMRC Research Fellowship: How does the bone marrow regulate normal blood formation and leukaemia progression.
    NHMRC Research Fellowship
    Open grant
  • 2013 - 2016
    Role of bone marrow cells in leukemia progression and resistance to chemotherapy
    NHMRC Project Grant
    Open grant
  • 2011 - 2012
    Comprehensive cell imaging facility (ARC LIEF Grant administered by QUT)
    ARC LIEF Collaborating/Partner Organisation Contributions
    Open grant
  • 2007 - 2012
    Interaction between PTH and Y2 bone anabolic pathways
    NHMRC Project Grant
    Open grant

Availability

Professor Jean-Pierre Levesque is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Completed supervision

Enquiries

For media enquiries about Professor Jean-Pierre Levesque's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au