Overview
Availability
- Professor Jean-Pierre Levesque is:
- Available for supervision
Works
Search Professor Jean-Pierre Levesque’s works on UQ eSpace
2019
Conference Publication
CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche
Erbani, Johanna D., Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre, Magnani, John L. and Winkler, Ingrid G. (2019). CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-132233
2019
Journal Article
Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2
Brennan, Faith H., Jogia, Trisha, Gillespie, Ellen R., Blomster, Linda V., Li, Xaria X., Nowlan, Bianca, Williams, Gail M., Jacobson, Esther, Osborne, Geoff W., Meunier, Frederic A., Taylor, Stephen M., Campbell, Kate E., MacDonald, Kelli P.A., Levesque, Jean-Pierre, Woodruff, Trent M. and Ruitenberg, Marc J. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI Insight, 4 (9) e98254. doi: 10.1172/jci.insight.98254
2019
Journal Article
Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury
Alexander, Kylie A., Tseng, Hsu-Wen, Fleming, Whitney, Jose, Beulah, Salga, Marjorie, Kulina, Irina, Millard, Susan M., Pettit, Allison R., Genet, Francois and Levesque, Jean-Pierre (2019). Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. Frontiers in Immunology, 10 (MAR) 377. doi: 10.3389/fimmu.2019.00377
2019
Journal Article
HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR
Bisht, Kavita, Brunck, Marion E., Matsumoto, Taichi, McGirr, Crystal, Nowlan, Bianca, Fleming, Whitney, Keech, Thomas, Magor, Graham, Perkins, Andrew C., Davies, Julie, Walkinshaw, Gail, Flippin, Lee, Winkler, Ingrid G. and Levesque, Jean-Pierre (2019). HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR. Blood Advances, 3 (3), 406-418. doi: 10.1182/bloodadvances.2018017566
2019
Journal Article
Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice
Salga, Marjorie, Tseng, Hsu-Wen, Alexander, Kylie A., Jose, Beulah, Vaquette, Cedryck, Debaud, Charlotte, Gatin, Laure, Genêt, François and Levesque, Jean-Pierre (2019). Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice. Annals of Physical and Rehabilitation Medicine, 62 (3), 189-192. doi: 10.1016/j.rehab.2019.01.005
2018
Journal Article
Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment
Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663
2018
Conference Publication
Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture
Winkler, Ingrid G., Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Magnani, John L., Marlton, Paula, Mills, Anthony K., Perkins, Andrew, Fiveash, Corrine E., Erbani, Johanna M. and Levesque, Jean-Pierre (2018). Vascular E-selectin acts as a gatekeeper inducing commitment and loss of self-renewal in HSC transmigrating through the marrow vasculture. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-120376
2018
Conference Publication
Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation
Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117
2018
Conference Publication
Prostaglandin I-2 in the endosteal bone marrow niche as a novel regulator of hematopoietic stem cells
Tay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Nowlan, Bianca, Barbier, Valerie and Winkler, Ingrid G. (2018). Prostaglandin I-2 in the endosteal bone marrow niche as a novel regulator of hematopoietic stem cells. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-115869
2018
Conference Publication
Understanding hematopoietic stem/progenitor cell responses after spinal cord injury
Jung, Won-Cheol, Jogia, Trisha, Gillespie, Ellen, Reid, Chantelle, Levesque, Jean-Pierre and Ruitenberg, Marc (2018). Understanding hematopoietic stem/progenitor cell responses after spinal cord injury. 3rd Joint Symposium of the International-and-National-Neurotrauma-Societies-and-AANS/CNS-Section on Neurotrauma and Critical Care, Toronto, Canada, 11-16 August 2018. New Rochelle, NY, United States: Mary Ann Liebert.
2017
Journal Article
Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms
Levesque, Jean-Pierre, Sims, Natalie A., Pettit, Allison R., Alexander, Kylie A., Tseng, Hsu-Wen, Torossian, Frédéric, Genêt, François, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms. Journal of Bone and Mineral Research, 33 (2), 365-366. doi: 10.1002/jbmr.3346
2017
Journal Article
Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications
Torossian, Frédéric, Guerton, Bernadette, Anginot, Adrienne, Alexander, Kylie A., Desterke, Christophe , Soave, Sabrina, Tseng, Hsu-Wen, Arouche, Nassim, Boutin, Laetitia, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Pettit, Allison R., Clay, Denis, Rochet, Nathalie, Vlachos, Erica, Genet, Guillaume, Debaud, Charlotte, Denormandie, Philippe, Genet, François, Sims, Natalie A., Banzet, Sébastien, Levesque, Jean-Pierre, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications. JCI Insight, 2 (21) e96034. doi: 10.1172/jci.insight.96034
2017
Conference Publication
Macrophage involvement in the response of acute myeloid leukaemia to chemotherapy
Keech, Thomas, McGirr, Crystal, Winkler, Ingrid G. and Levesque, Jean-Pierre (2017). Macrophage involvement in the response of acute myeloid leukaemia to chemotherapy. 59th Annual Meeting of the American Society of Hematology (ASH), Atlanta, GA USA, 9-12 December 2017. Washington, DC USA: American Society of Hematology.
2017
Conference Publication
Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling
Winkler, Ingrid G., Erbani, Johanna M., Barbier, Valerie, Davies, Julie M., Tay, Joshua, Fiveash, Corrine E., Lowe, Jessica, Tallack, Michael, Magnani, John L. and Levesque, Jean-Pierre (2017). Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling. 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 9-12 December 2017. Washington, DC, United States: American Society of Hematology.
2017
Journal Article
CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair
Batoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033
2017
Journal Article
Peripheral denervation participates in heterotopic ossification in a spinal cord injury model
Debaud, Charlotte, Salga, Marjorie, Begot, Laurent, Holy, Xavier, Chedik, Malha, de l'Escalopier, Nicolas, Torossian, Frederic, Levesque, Jean-Pierre, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Genet, Francois (2017). Peripheral denervation participates in heterotopic ossification in a spinal cord injury model. PLoS One, 12 (8) e0182454, e0182454. doi: 10.1371/journal.pone.0182454
2017
Journal Article
HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice
Nowlan, Bianca, Futrega, Kathryn, Brunck, Marion, Walkinshaw, Gail, Flippin, Lee E., Doran, Michael R. and Levesque, Jean-Pierre (2017). HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice. Experimental Hematology, 52, 50-55. doi: 10.1016/j.exphem.2017.05.004
2017
Journal Article
Engineering a humanized bone organ model in mice to study bone metastases
Martine, Laure C., Holzapfel, Boris M., McGovern, Jacqui A., Wagner, Ferdinand, Quent, Verena M., Hesami, Parisa, Wunner, Felix M., Vaquette, Cedryck, De-Juan-Pardo, Elena M., Brown, Toby D., Nowlan, Bianca, Wu, Dan Jing, Hutmacher, Cosmo Orlando, Moi, Davide, Oussenko, Tatiana, Piccinini, Elia, Zandstra, Peter W., Mazzieri, Roberta, Levesque, Jean-Pierre, Dalton, Paul D., Taubenberger, Anna V. and Hutmacher, Dietmar W. (2017). Engineering a humanized bone organ model in mice to study bone metastases. Nature Protocols, 12 (4), 639-663. doi: 10.1038/nprot.2017.002
2017
Journal Article
Cellular players of hematopoietic stem cell mobilization in the bone marrow niche
Tay, Joshua, Levesque, Jean‑Pierre and Winkler, Ingrid G. (2017). Cellular players of hematopoietic stem cell mobilization in the bone marrow niche. International Journal of Hematology, 105 (2), 129-140. doi: 10.1007/s12185-016-2162-4
2017
Journal Article
It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function
Jung, Won-Cheol, Levesque, Jean-Pierre and Ruitenberg, Marc J. (2017). It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function. Seminars in Cell and Developmental Biology, 61, 60-70. doi: 10.1016/j.semcdb.2016.08.010
Funding
Current funding
Supervision
Availability
- Professor Jean-Pierre Levesque is:
- Available for supervision
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Supervision history
Completed supervision
-
2023
Doctor Philosophy
Role of infections and gut microflora in the development of neurogenic heterotopic ossifications following spinal cord injury in a mouse model
Principal Advisor
Other advisors: Dr Kylie Alexander
-
2021
Doctor Philosophy
The Role of Macrophages in Acute Myeloid Leukaemia Progression and Sensitivity to Chemotherapy
Principal Advisor
Other advisors: Dr Ingrid Winkler
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2015
Doctor Philosophy
Role of Bone Marrow Macrophages in Regulating Haematopoiesis
Principal Advisor
Other advisors: Dr Ingrid Winkler
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2011
Doctor Philosophy
The Role of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in Haematopoiesis
Principal Advisor
Other advisors: Dr Ingrid Winkler
-
2019
Doctor Philosophy
Understanding the splenic regulation of the monocyte trafficking during spinal cord injury
Associate Advisor
Other advisors: Professor Marc Ruitenberg
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2019
Doctor Philosophy
The role of bone marrow niches in the regulation of normal and malignant haematopoietic stem cells
Associate Advisor
Other advisors: Dr Ingrid Winkler
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2018
Doctor Philosophy
The role of macrophages in facilitating haematopoietic stem cell engraftment and reconstitution
Associate Advisor
Other advisors: Dr Liza Raggatt, Professor Allison Pettit
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2017
Doctor Philosophy
The role of prostaglandin I2 in haematopoietic stem cell in the bone marrow niche
Associate Advisor
Other advisors: Dr Ingrid Winkler
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2015
Doctor Philosophy
Understanding heterotopic ossification after spinal cord injury
Associate Advisor
Other advisors: Dr Ingrid Winkler
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