Overview
Availability
- Professor Jean-Pierre Levesque is:
- Available for supervision
Works
Search Professor Jean-Pierre Levesque’s works on UQ eSpace
2013
Journal Article
The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor
Karpova, D., Dauber, K., Spohn, G., Chudziak, D., Wiercinska, E., Schulz, M., Pettit, A. R., Levesque, J. P., Romagnoli, B., Patel, K., Chevalier, E., Dembowsky, K. and Bonig, H. (2013). The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor. Leukemia, 27 (12), 2322-2331. doi: 10.1038/leu.2013.266
2012
Conference Publication
FG-4497, a Pharmacological Stabilizer of HIF-1 alpha Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and Plerixafor
Forristal, Catherine E., Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid G., Walkinshaw, Gail and Levesque, Jean-Pierre (2012). FG-4497, a Pharmacological Stabilizer of HIF-1 alpha Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and Plerixafor. 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 8-11 December 2012. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V120.21.216.216
2012
Journal Article
Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance
Winkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Jacobsen, Rebecca N., Forristal, Catherine E., Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2012). Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance. Nature Medicine, 18 (11), 1651-1657. doi: 10.1038/nm.2969
2012
Journal Article
Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation
Winkler, I. G., Pettit, A. R., Raggatt, L. J., Jacobsen, R. N., Forristal, C. E., Barbier, V., Nowlan, B., Cisterne, A., Bendall, L. J., Sims, N. A. and Levesque, J-P. (2012). Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia, 26 (7), 1594-1601. doi: 10.1038/leu.2012.17
2012
Journal Article
N(o)-cadherin role for HSCs
Levesque, Jean-Pierre (2012). N(o)-cadherin role for HSCs. Blood, 120 (2), 237-238. doi: 10.1182/blood-2012-05-431148
2012
Book Chapter
Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells
Barbier, Valérie, Nowlan, Bianca, Lévesque, Jean-Pierre and Winkler, Ingrid G. (2012). Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells. Leucocytes: methods and protocols. (pp. 31-43) edited by Ashman, RB. New York, United States: Humana Press. doi: 10.1007/978-1-61779-527-5_3
2012
Conference Publication
Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the niche
Levesque, Jean-Pierre, Forristal, Catherine and Winkler, Ingrid (2012). Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the niche. 41st Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Amsterdam Netherlands, 23-26 August 2012. Philadelphia, PA United States: Elsevier.
2012
Book Chapter
Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo
Barbier, Valérie, Winkler, Ingrid G., Wadley, Robert and Lévesque, Jean-Pierre (2012). Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo. Leucocytes: methods and protocols. (pp. 45-63) edited by Ashman, RB. New York, United States: Humana Press. doi: 10.1007/978-1-61779-527-5_4
2012
Book Chapter
Mobilization of hematopoietic stem cells by depleting bone marrow macrophages
Barbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Paul (2012). Mobilization of hematopoietic stem cells by depleting bone marrow macrophages. In Stem cell mobilization: methods and protocols (pp. 117-137) New York, United States: Humana Press. doi:10.1007/978-1-61779-943-3_11
2012
Conference Publication
Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia by human AML oncogenes, and represents a potential therapeutic target
Pattabiraman, Diwakar R., Shakhbazov, Konstantin, Barbier, Valerie, McGirr, Crystal, Krishnan, Keerthana, Mukhopadhyay, Pamela, Hawthorne, Paula, Trezise, Ann, Grimmond, Sean, Papathanasiou, Peter, Perkins, Andrew C., Levesque, Jean-Pierre, Alexander, Warren S., Winkler, Ingrid G. and Gonda, Thomas J. (2012). Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia by human AML oncogenes, and represents a potential therapeutic target. 54th Annual Meeting and Exposition of the American Society of Hematology (ASH), Atlanta, GA, United States, 8-11 Deceember, 2012. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V120.21.2402.2402
2011
Conference Publication
Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF
Forristal, Catherine, Nowlan, Bianca, Barbier, Valerie, McCarthy, Domenica, Walkinshaw, Gail, Winkler, Ingrid G. and Levesque, Jean-Pierre (2011). Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.
2011
Conference Publication
Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow
Levesque, Jean-Pierre, Barbier, Valerie, Nowlan, Bianca, McCarhty, Domenica and Winkler, Ingrid G. (2011). Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.
2011
Journal Article
Mobilisation strategies for normal and malignant cells
To, L. Bik, Levesque, Jean-Pierre, Herbert, Kirsten E., Winkler, Ingrid G., Bendall, Linda J., Hiwase, Devendra K., Antonenas, Vicki, Rice, Alison M., Gottlieb, David, Mills, Anthony K., Rasko, John E. J., Larsen, Stephen, Beligaswatte, Ashanka, Nilsson, Susan K., Cooney, Julian P., Cambareri, Antony C. and Lewis, Ian D. (2011). Mobilisation strategies for normal and malignant cells. Pathology, 43 (6), 547-565. doi: 10.1097/PAT.0b013e32834a9eb8
2011
Journal Article
How I treat patients who mobilize hematopoietic stem cells poorly
To, L. Bik, Levesque, Jean-Pierre and Herbert, Kirsten E. (2011). How I treat patients who mobilize hematopoietic stem cells poorly. Blood, 118 (17), 4530-4540. doi: 10.1182/blood-2011-06-318220
2011
Journal Article
How we mobilize haemopoietic stem cells
Herbert, K.E., Levesque, J.P., Mills, A.K., Gottlieb, D.J., Cooney, J., Szer, J., Rasko, J. and To, L.B. (2011). How we mobilize haemopoietic stem cells. Internal Medicine Journal, 41 (8), 588-594. doi: 10.1111/j.1445-5994.2011.02544.x
2011
Conference Publication
Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis
Levesque, Jean-Pierre, Bendall, Linda J., Pettit, Allison R., Raggatt, Liza, Jacobsen, Rebecca, Barbier, Valarie, Nowlan, Bianca, Shen, Yi Shen, Sims, Natalie A. and Winkler, Ingrid G. (2011). Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.
2011
Journal Article
Hierarchy of immature hematopoietic cells related to blood flow and niche
Levesque, Jean-Pierre and Winkler, Ingrid G. (2011). Hierarchy of immature hematopoietic cells related to blood flow and niche. Current Opinion in Hematology, 18 (4), 220-225. doi: 10.1097/MOH.0b013e3283475fe7
2010
Journal Article
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
Winkler, Ingrid G., Sims, Natalie A., Pettit, Allison R., Barbier, Valérie, Nowlan, Bianca, Helwani, Falak, Poulton, Ingrid J., van Rooijen, Nico van, Alexander, Kylie A., Raggatt, Liza J. and Levesque, Jean-Pierre (2010). Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood, 116 (23), 4815-4828. doi: 10.1182/blood-2009-11-253534
2010
Journal Article
The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization
Lévesque, J.-P., Helwani, F. M. and Winkler, I. G. (2010). The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization. Leukemia, 24 (12), 1979-1992. doi: 10.1038/leu.2010.214
2010
Journal Article
Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo
Shen, Yi, Winkler, Ingrid G., Barbier, Valerie, Sims, Natalie A., Hendy, Jean and Lévesque, Jean-Pierre (2010). Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo. PLoS One, 5 (9) e13086, e13086-1-e13086-13. doi: 10.1371/journal.pone.0013086
Funding
Supervision
Availability
- Professor Jean-Pierre Levesque is:
- Available for supervision
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Supervision history
Completed supervision
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2023
Doctor Philosophy
Role of infections and gut microflora in the development of neurogenic heterotopic ossifications following spinal cord injury in a mouse model
Principal Advisor
Other advisors: Dr Kylie Alexander
-
2021
Doctor Philosophy
The Role of Macrophages in Acute Myeloid Leukaemia Progression and Sensitivity to Chemotherapy
Principal Advisor
Other advisors: Dr Ingrid Winkler
-
2015
Doctor Philosophy
Role of Bone Marrow Macrophages in Regulating Haematopoiesis
Principal Advisor
Other advisors: Dr Ingrid Winkler
-
2011
Doctor Philosophy
The Role of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in Haematopoiesis
Principal Advisor
Other advisors: Dr Ingrid Winkler
-
2019
Doctor Philosophy
Understanding the splenic regulation of the monocyte trafficking during spinal cord injury
Associate Advisor
Other advisors: Professor Marc Ruitenberg
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2019
Doctor Philosophy
The role of bone marrow niches in the regulation of normal and malignant haematopoietic stem cells
Associate Advisor
Other advisors: Dr Ingrid Winkler
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2018
Doctor Philosophy
The role of macrophages in facilitating haematopoietic stem cell engraftment and reconstitution
Associate Advisor
Other advisors: Dr Liza Raggatt, Professor Allison Pettit
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2017
Doctor Philosophy
The role of prostaglandin I2 in haematopoietic stem cell in the bone marrow niche
Associate Advisor
Other advisors: Dr Ingrid Winkler
-
2015
Doctor Philosophy
Understanding heterotopic ossification after spinal cord injury
Associate Advisor
Other advisors: Dr Ingrid Winkler
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