Professor

Jean-Pierre Levesque

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Professor Jean-Pierre Levesque is:
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Search Professor Jean-Pierre Levesque’s works on UQ eSpace

221 works between 1985 and 2025
All (221) Journal Article (145) Conference Publication (70) Book Chapter (6)

161 - 180 of 221 works

2003

Journal Article

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamide

Levesque, JP, Hendy, J, Takamatsu, Y, Simmons, PJ and Bendall, LJ (2003). Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamide. Journal of Clinical Investigation, 111 (2), 187-196. doi: 10.1172/JCI200315994

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamide

2002

Conference Publication

Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization

Levesque, J. P., Hendy, J., Winkler, I. G., Takamatsu, Y. and Simmons, P. J. (2002). Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization. 44th Annual Meeting of the American-Society-of-Hematology, Philadelphia, PA, United States, 6-10 December 2002. Washington, DC, United States: American Society of Hematology.

Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization

2002

Journal Article

A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29)

Levesque, JP, Takada, Y, Puzon-McLaughlin, W and Simmons, PJ (2002). A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29). Hybridoma and Hybridomics, 21 (4), 253-260. doi: 10.1089/153685902760213868

A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29)

2002

Journal Article

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment

Levesque, JP, Hendy, J, Takamatsu, Y, Williams, B, Winkler, IG and Simmons, PJ (2002). Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment. Experimental Hematology, 30 (5), 440-449. doi: 10.1016/S0301-472X(02)00788-9

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment

2001

Conference Publication

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells

Winkler, IG, Eto, T, Purton, LE, Haylock, DN, Snapp, KR, Kansas, GS, Simmons, PJ and Levesque, JP (2001). Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells. Unknown, Unknown, Unknown. Washington, DC United States: American Society of Hematology.

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells

2001

Conference Publication

VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy

Levesque, J. P., Hendy, J., Takamatsu, Y., Williams, B., Winkler, I. G. and Simmons, P. J. (2001). VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy. *, *, *. Washington, DC, United States: American Society of Hematology.

VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy

2001

Journal Article

Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor

Levesque, Jean-Pierre, Takamatsu, Yasushi, Nilsson, Yasushi, Haylock, Yasushi and Simmons, Yasushi (2001). Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor. Blood, 98 (5), 1289-1297. doi: 10.1182/blood.V98.5.1289

Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor

2001

Conference Publication

Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells

Simmons, P. J., Levesque, J. P., Haylock, D. N., Eaves, C. J. and Bühring, H. J. (2001). Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells. Hematopoietic Stem Cells 2000: Basic and Clinical Sciences: Third International Conference, Unknown, June 2001. Malden, MA United States: New York Academy of Sciences. doi: 10.1111/j.1749-6632.2001.tb03590.x

Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells

2001

Journal Article

Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells

Simmons, PJ, Levesque, JP and Haylock, DN (2001). Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells. Hematopoietic Stem Cells 2000 Basic and Clinical Sciences, 938, 196-207.

Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells

2001

Journal Article

Role of integrins and selectins in the development and regulation of the hematopoietic system

Lévesque, J. P., Takamatsu, Y., Nilsson, S. K., Haylock, D. N. and Simmons, P. J. (2001). Role of integrins and selectins in the development and regulation of the hematopoietic system. Hematologie, 7 (2), 99-109.

Role of integrins and selectins in the development and regulation of the hematopoietic system

2000

Journal Article

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow

Levesque, J. P., Takamatsu, Y., Nilsson, S. K., Haylock, D. N. and Simmons, P. J. (2000). Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow. Blood, 96 (11 PART I).

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow

2000

Conference Publication

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.

Levesque, JP, Takamatsu, Y, Nilsson, SK, Haylock, DN and Simmons, PJ (2000). Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.. WASHINGTON: AMER SOC HEMATOLOGY.

Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.

2000

Journal Article

CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor

Doyonnas, R, Chan, JYH, Butler, LH, Rappold, I, Lee-Prudhoe, JE, Zannettino, ACW, Simmons, PJ, Buhring, HJ, Levesque, JP and Watt, SM (2000). CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor. Journal of Immunology, 165 (2), 840-851. doi: 10.4049/jimmunol.165.2.840

CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor

2000

Journal Article

Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues

Watt, SM, Butler, LH, Tavian, M, Buhring, HJ, Rappold, I, Simmons, PJ, Zannettino, ACW, Buck, D, Fuchs, A, Doyonnas, R, Chan, JYH, Levesque, JP, Peault, B and Roxanis, I (2000). Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues. Blood, 95 (10), 3113-3124.

Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues

1999

Journal Article

Cytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cells

Levesque, JP and Simmons, PJ (1999). Cytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cells. Experimental Hematology, 27 (4), 579-586. doi: 10.1016/S0301-472X(98)00069-1

Cytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cells

1999

Journal Article

PSGL-1-mediated adhesion of human hematopoietic progenitors to P- selectin results in suppression of hematopoiesis

Levesque, JP, Zannettino, ACW, Pudney, M, Niutta, S, Haylock, DN, Snapp, KR, Kansas, GS, Berndt, MC and Simmons, PJ (1999). PSGL-1-mediated adhesion of human hematopoietic progenitors to P- selectin results in suppression of hematopoiesis. Immunity, 11 (3), 369-378. doi: 10.1016/S1074-7613(00)80112-0

PSGL-1-mediated adhesion of human hematopoietic progenitors to P- selectin results in suppression of hematopoiesis

1999

Journal Article

CD44 isoforms in normal and leukemic hematopoiesis

Ghaffari, S, Smadja-Joffe, F, Oostendorp, R, Levesque, JP, Dougherty, G, Eaves, A and Eaves, C (1999). CD44 isoforms in normal and leukemic hematopoiesis. Experimental Hematology, 27 (6), 978-993. doi: 10.1016/S0301-472X(99)00023-5

CD44 isoforms in normal and leukemic hematopoiesis

1998

Journal Article

Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization

Takamatsu, Y, Simmons, PJ, Moore, RJ, Morris, HA, To, LB and Levesque, JP (1998). Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization. Blood, 92 (9), 3465-3473. doi: 10.1182/blood.v92.9.3465.421k35_3465_3473

Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization

1998

Journal Article

Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cells

Moore, S, Haylock, DN, Levesque, JP, McDiarmid, LA, Samels, LM, To, LB, Simmons, PJ and Hughes, TP (1998). Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cells. Blood, 92 (7), 2461-2470. doi: 10.1182/blood.v92.7.2461.2461_2461_2470

Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cells

1998

Journal Article

CD44 and hematopoiesis CD44 et hematopoiese

Smadja-Joffe, Florence, Charrad, Rachida-Sihem, Legras, Stéphane, Gadhoum, Zeineb and Lévesque, Jean-Pierre (1998). CD44 and hematopoiesis CD44 et hematopoiese. Hematologie, 4 (5), 339-349.

CD44 and hematopoiesis CD44 et hematopoiese

Current funding

  • 2025 - 2028
    Mechanisms and first prophylactic treatments of neurogenic heterotopic ossifications
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2024
    Discovering the mechanisms of neurogenic heterotopic ossifications following spinal cord injuries
    NHMRC IDEAS Grants
    Open grant
  • 2018 - 2020
    Colony-stimulating factor 1 receptor tyrosine kinase, a new target to treat acute myeloid leukemia
    Cancer Council Queensland
    Open grant
  • 2018 - 2020
    Increasing haematopoietic stem cell mobilisation by targeting a novel niche factor
    NHMRC Project Grant
    Open grant
  • 2018 - 2022
    Stem cell niches: Biology and therapeutic applications
    NHMRC Research Fellowship
    Open grant
  • 2017 - 2020
    Mechanisms by which Endothelial Selectins regulate Normal and Malignant Stem Cell fate
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Recipient bone marrow macrophages contribute to haematopoietic stem cell transplantation success
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Why macrophages promote heterotopic ossifications following spinal cord injuries
    NHMRC Project Grant
    Open grant
  • 2015 - 2019
    Mechanisms and Treatments of Heterotopic Ossification following Spinal Cord Injuries
    United States Congressionally Directed Medical Research Programs - Spinal Cord Injury Research Program
    Open grant
  • 2015 - 2017
    A preclinical humanized chimeric model to investigate novel therapeutic strategies against breast cancer bone metastasis (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2015 - 2018
    Haematopoietic Stem Cell glycome regulates outcome of niche interactions
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Targeting the hypoxia sensing pathway to improve hematopoietic stem cell mobilisation and transplantation
    NHMRC Project Grant
    Open grant
  • 2014 - 2015
    The role of macrophages in facilitating hematopoietic stem cell engraftment and reconstitution
    Cancer Council Queensland
    Open grant
  • 2013 - 2017
    NHMRC Research Fellowship: How does the bone marrow regulate normal blood formation and leukaemia progression.
    NHMRC Research Fellowship
    Open grant
  • 2013 - 2016
    Role of bone marrow cells in leukemia progression and resistance to chemotherapy
    NHMRC Project Grant
    Open grant
  • 2011 - 2012
    Comprehensive cell imaging facility (ARC LIEF Grant administered by QUT)
    ARC LIEF Collaborating/Partner Organisation Contributions
    Open grant
  • 2007 - 2012
    Interaction between PTH and Y2 bone anabolic pathways
    NHMRC Project Grant
    Open grant

Availability

Professor Jean-Pierre Levesque is:
Available for supervision

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Supervision history

Completed supervision

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