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Dr Kylie Alexander
Dr

Kylie Alexander

Email: 

Overview

Availability

Dr Kylie Alexander is:
Available for supervision

Qualifications

  • Bachelor, Griffith University
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Neurogenic heterotopic ossification

  • Macrophage biology and inflammation

Works

Search Professor Kylie Alexander’s works on UQ eSpace

65 works between 2007 and 2025

1 - 20 of 65 works

2025

Journal Article

A partnership between the Australian and New Zealand Bone and Mineral Society (ANZBMS) and Bone: Highlights from the 2024 annual scientific meeting

Sim, Marc, Alexander, Kylie A., Sims, Natalie A., Reid, Ian R. and Forwood, Mark (2025). A partnership between the Australian and New Zealand Bone and Mineral Society (ANZBMS) and Bone: Highlights from the 2024 annual scientific meeting. Bone, 198 117540, 117540-198. doi: 10.1016/j.bone.2025.117540

A partnership between the Australian and New Zealand Bone and Mineral Society (ANZBMS) and Bone: Highlights from the 2024 annual scientific meeting

2025

Journal Article

Role of endocrinal dysregulations in traumatic heterotopic ossification pathogenesis

Lévesque, Jean-Pierre and Alexander, Kylie A. (2025). Role of endocrinal dysregulations in traumatic heterotopic ossification pathogenesis. Current Opinion in Endocrinology, Diabetes and Obesity, 32 (4) 0913, 156-165. doi: 10.1097/MED.0000000000000913

Role of endocrinal dysregulations in traumatic heterotopic ossification pathogenesis

2024

Journal Article

A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury

Alexander, Kylie A., Tseng, Hsu-Wen, Lao, Hong Wa, Girard, Dorothée, Barbier, Valérie, Ungerer, Jacobus P. J., McWhinney, Brett C., Samuel, Selwin G., Fleming, Whitney, Winkler, Ingrid G., Salga, Marjorie, Genêt, François, Banzet, Sébastien, Ruitenberg, Marc J. and Lévesque, Jean-Pierre (2024). A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury. Cell Reports Medicine, 5 (12) 101849, 101849. doi: 10.1016/j.xcrm.2024.101849

A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury

2024

Conference Publication

Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia

Bisht, Kavita, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Giri, Rabina, Amiss, Anna, Tang, Yifu, Alexander, Kylie, Millard, Susan, Winkler, Ingrid G., Pettit, Allison, Begun, Jakob and Levesque, Jean-Pierre (2024). Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-193349

Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia

2024

Conference Publication

Pathogen-associated molecular patterns enhance neurogenic heterotopic ossifications after spinal-cord injury

Samuel, Selwin G., Tseng, Hsu-Wen, Girard, Dorothee, Rival, Bastien, Barbier, Valerie, Fleming, Whitney, Salga, Marjorie, Genet, Francois, Banzet, Sebastien, Alexander, Kylie and Levesque, Jean-Pierre (2024). Pathogen-associated molecular patterns enhance neurogenic heterotopic ossifications after spinal-cord injury. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Toronto, Canada, 27-30 September 2024. Oxford, United Kingdom: Oxford University Press.

Pathogen-associated molecular patterns enhance neurogenic heterotopic ossifications after spinal-cord injury

2024

Journal Article

Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesis

Girard, Dorothee, Tseng, Hsu-Wen, Rival, Bastien, Barbier, Valerie, Shatunova, Svetlana, Goriot, Marie-Emmanuelle, Samuel, Selwin Gabriel, Genet, Francois, Salga, Marjorie, Banzet, Sebastien, Alexander, Kylie A. and Levesque, Jean-Pierre (2024). Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesis. Neurotrauma Reports, 5 (1), 1101-1112. doi: 10.1089/neur.2024.0106

Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesis

2024

Conference Publication

Endogenous glucocorticoids promote neurogenic heterotopic ossification after spinal cord injury and glucocorticoid receptor antagonist treatment prevents their development

Alexander, Kylie, Tseng, Hsu-Wen, Girard, Dorothee, Barbier, Valerie, Lao, Hong Wa, Samuel, Selwin G., Ungerer, Jacobus P. J., McWhinney, Brett C., Fleming, Whitney, Salga, Marjorie, Genet, Francois, Ruitenberg, Mark J., Banzet, Sebastien and Levesque, Jean-Pierre (2024). Endogenous glucocorticoids promote neurogenic heterotopic ossification after spinal cord injury and glucocorticoid receptor antagonist treatment prevents their development. 2024 Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), Toronto, ON, Canada, 27-30 September 2024. Cary, NC, United States: Oxford University Press. doi: 10.1093/jbmr/zjae183

Endogenous glucocorticoids promote neurogenic heterotopic ossification after spinal cord injury and glucocorticoid receptor antagonist treatment prevents their development

2023

Journal Article

Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development

Salga, Marjorie, Samuel, Selwin G., Tseng, Hsu‐Wen, Gatin, Laure, Girard, Dorothée, Rival, Bastien, Barbier, Valerie, Bisht, Kavita, Shatunova, Svetlana, Debaud, Charlotte, Winkler, Ingrid G., Paquereau, Julie, Dinh, Aurélien, Genêt, Guillaume, Kerever, Sébastien, Abback, Paer‐Sélim, Banzet, Sébastien, Genêt, François, Lévesque, Jean‐Pierre and Alexander, Kylie A. (2023). Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development. Journal of Bone and Mineral Research, 38 (11), 1-18. doi: 10.1002/jbmr.4905

Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development

2023

Conference Publication

Gut microflora does not contribute to Neurogenic Heterotopic Ossification after SCI

Samuel, Selwin, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie and Levesque, Jean-Pierre (2023). Gut microflora does not contribute to Neurogenic Heterotopic Ossification after SCI. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX USA, 9-12 September 2022. Cary, NC USA: Oxford University Press.

Gut microflora does not contribute to Neurogenic Heterotopic Ossification after SCI

2023

Conference Publication

Pathogen-associated molecular patterns exacerbate neurogenic heterotopic ossifications after spinal cord injury

Samuel, Selwin, Salga, Marjorie, Tseng, Hsu-Wen, Fleming, Whitney, Genet, Francois, Alexander, Kylie and Levesque, Jean-Pierre (2023). Pathogen-associated molecular patterns exacerbate neurogenic heterotopic ossifications after spinal cord injury. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX USA, 9-12 September 2022. Cary, NC USA: Oxford University Press.

Pathogen-associated molecular patterns exacerbate neurogenic heterotopic ossifications after spinal cord injury

2022

Journal Article

Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors

Gartlan, Kate H., Jaiswal, Jagdish K., Bull, Matthew R., Akhlaghi, Hedieh, Sutton, Vivien R., Alexander, Kylie A., Chang, Karshing, Hill, Geoffrey R., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Trapani, Joseph A., Charman, Susan A., Spicer, Julie A. and Jamieson, Stephen M. F. (2022). Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors. ACS Pharmacology and Translational Science, 5 (6), 429-439. doi: 10.1021/acsptsci.2c00009

Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors

2022

Journal Article

Inflammasomes and the IL-1 family in bone homeostasis and disease

Tseng, Hsu-Wen, Samuel, Selwin Gabriel, Schroder, Kate, Lévesque, Jean-Pierre and Alexander, Kylie A (2022). Inflammasomes and the IL-1 family in bone homeostasis and disease. Current Osteoporosis Reports, 20 (3), 170-185. doi: 10.1007/s11914-022-00729-8

Inflammasomes and the IL-1 family in bone homeostasis and disease

2022

Journal Article

Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

Tseng, Hsu‐Wen, Kulina, Irina, Girard, Dorothée, Gueguen, Jules, Vaquette, Cedryck, Salga, Marjorie, Fleming, Whitney, Jose, Beulah, Millard, Susan M., Pettit, Allison R., Schroder, Kate, Thomas, Gethin, Wheeler, Lawrie, Genêt, François, Banzet, Sébastien, Alexander, Kylie A. and Levesque, Jean‐Pierre (2022). Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification. Journal of Bone and Mineral Research, 37 (3), 531-546. doi: 10.1002/jbmr.4482

Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

2022

Journal Article

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Tseng, Hsu-Wen, Girard, Dorothée, Alexander, Kylie A., Millard, Susan M., Torossian, Frédéric, Anginot, Adrienne, Fleming, Whitney, Gueguen, Jules, Goriot, Marie-Emmanuelle, Clay, Denis, Jose, Beulah, Nowlan, Bianca, Pettit, Allison R., Salga, Marjorie, Genêt, François, Bousse-Kerdilès, Marie-Caroline Le, Banzet, Sébastien and Lévesque, Jean-Pierre (2022). Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone Research, 10 (1) 22, 22. doi: 10.1038/s41413-022-00188-y

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

2022

Journal Article

Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injury

Alexander, Kylie A., Tseng, Hsu-Wen, Kulina, Irina, Fleming, Whitney, Vaquette, Cedryck, Genêt, François, Ruitenberg, Marc J. and Lévesque, Jean-Pierre (2022). Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injury. Neurotrauma Reports, 3 (1), 87-96. doi: 10.1089/neur.2021.0072

Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injury

2021

Journal Article

Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization

Bisht, Kavita, McGirr, Crystal, Lee, Seo-Youn, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie A., Matsumoto, Taichi, Barbier, Valérie, Sims, Natalie A., Müller-Newen, Gerhard, Winkler, Ingrid G., Bonig, Halvard and Lévesque, Jean-Pierre (2021). Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization. Leukemia, 36 (2), 333-347. doi: 10.1038/s41375-021-01413-z

Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization

2021

Journal Article

Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environment

Girard, Dorothée, Torossian, Frédéric, Oberlin, Estelle, Alexander, Kylie A., Gueguen, Jules, Tseng, Hsu-Wen, Genêt, François, Lataillade, Jean-Jacques, Salga, Marjorie, Levesque, Jean-Pierre, Le Bousse-Kerdilès, Marie-Caroline and Banzet, Sébastien (2021). Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environment. Frontiers in Cell and Developmental Biology, 9 611842, 611842. doi: 10.3389/fcell.2021.611842

Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environment

2020

Journal Article

Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils

Tseng, Hsu‐Wen, Kulina, Irina, Salga, Marjorie, Fleming, Whitney, Vaquette, Cedryck, Genêt, François, Levesque, Jean‐Pierre and Alexander, Kylie A (2020). Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils. Journal of Bone and Mineral Research, 35 (11) jbmr.4118, 2242-2251. doi: 10.1002/jbmr.4118

Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils

2020

Journal Article

When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification

Alexander, Kylie A., Tseng, Hsu-Wen, Salga, Marjorie, Genêt, François and Levesque, Jean-Pierre (2020). When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification. Current Osteoporosis Reports, 18 (6), 666-676. doi: 10.1007/s11914-020-00636-w

When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification

2019

Journal Article

Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor

Bisht, Kavita, McGirr, Crystal, Alexander, Kylie A, Fleming, Whitney, Sims, Natalie, Newen, Gerhard Müller-, Winkler, Ingrid G and Levesque, Jean-Pierre (2019). Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor. Blood, 134 (Supplement_1), 4469-4469. doi: 10.1182/blood-2019-127431

Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor

Funding

Current funding

  • 2025 - 2028
    Mechanisms and first prophylactic treatments of neurogenic heterotopic ossifications
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2024
    Discovering the mechanisms of neurogenic heterotopic ossifications following spinal cord injuries
    NHMRC IDEAS Grants
    Open grant
  • 2018
    Delineating the mechanisms of neurogenic heterotopic ossification development after spinal cord injury
    UQ Early Career Researcher
    Open grant

Supervision

Availability

Dr Kylie Alexander is:
Available for supervision

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Media

Enquiries

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