Overview
Availability
- Dr Kylie Alexander is:
- Available for supervision
Qualifications
- Bachelor, Griffith University
- Doctor of Philosophy, The University of Queensland
Research interests
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Neurogenic heterotopic ossification
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Macrophage biology and inflammation
Works
Search Professor Kylie Alexander’s works on UQ eSpace
2025
Journal Article
A partnership between the Australian and New Zealand Bone and Mineral Society (ANZBMS) and Bone: Highlights from the 2024 annual scientific meeting
Sim, Marc, Alexander, Kylie A., Sims, Natalie A., Reid, Ian R. and Forwood, Mark (2025). A partnership between the Australian and New Zealand Bone and Mineral Society (ANZBMS) and Bone: Highlights from the 2024 annual scientific meeting. Bone, 198 117540, 117540-198. doi: 10.1016/j.bone.2025.117540
2025
Journal Article
Role of endocrinal dysregulations in traumatic heterotopic ossification pathogenesis
Lévesque, Jean-Pierre and Alexander, Kylie A. (2025). Role of endocrinal dysregulations in traumatic heterotopic ossification pathogenesis. Current Opinion in Endocrinology, Diabetes and Obesity, 32 (4) 0913, 156-165. doi: 10.1097/MED.0000000000000913
2024
Journal Article
A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury
Alexander, Kylie A., Tseng, Hsu-Wen, Lao, Hong Wa, Girard, Dorothée, Barbier, Valérie, Ungerer, Jacobus P. J., McWhinney, Brett C., Samuel, Selwin G., Fleming, Whitney, Winkler, Ingrid G., Salga, Marjorie, Genêt, François, Banzet, Sébastien, Ruitenberg, Marc J. and Lévesque, Jean-Pierre (2024). A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury. Cell Reports Medicine, 5 (12) 101849, 101849. doi: 10.1016/j.xcrm.2024.101849
2024
Conference Publication
Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia
Bisht, Kavita, An, Yoon-Kyo, Shatunova, Svetlana, Wang, Ran, Barbier, Valerie, Giri, Rabina, Amiss, Anna, Tang, Yifu, Alexander, Kylie, Millard, Susan, Winkler, Ingrid G., Pettit, Allison, Begun, Jakob and Levesque, Jean-Pierre (2024). Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-193349
2024
Conference Publication
Pathogen-associated molecular patterns enhance neurogenic heterotopic ossifications after spinal-cord injury
Samuel, Selwin G., Tseng, Hsu-Wen, Girard, Dorothee, Rival, Bastien, Barbier, Valerie, Fleming, Whitney, Salga, Marjorie, Genet, Francois, Banzet, Sebastien, Alexander, Kylie and Levesque, Jean-Pierre (2024). Pathogen-associated molecular patterns enhance neurogenic heterotopic ossifications after spinal-cord injury. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Toronto, Canada, 27-30 September 2024. Oxford, United Kingdom: Oxford University Press.
2024
Journal Article
Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesis
Girard, Dorothee, Tseng, Hsu-Wen, Rival, Bastien, Barbier, Valerie, Shatunova, Svetlana, Goriot, Marie-Emmanuelle, Samuel, Selwin Gabriel, Genet, Francois, Salga, Marjorie, Banzet, Sebastien, Alexander, Kylie A. and Levesque, Jean-Pierre (2024). Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesis. Neurotrauma Reports, 5 (1), 1101-1112. doi: 10.1089/neur.2024.0106
2024
Conference Publication
Endogenous glucocorticoids promote neurogenic heterotopic ossification after spinal cord injury and glucocorticoid receptor antagonist treatment prevents their development
Alexander, Kylie, Tseng, Hsu-Wen, Girard, Dorothee, Barbier, Valerie, Lao, Hong Wa, Samuel, Selwin G., Ungerer, Jacobus P. J., McWhinney, Brett C., Fleming, Whitney, Salga, Marjorie, Genet, Francois, Ruitenberg, Mark J., Banzet, Sebastien and Levesque, Jean-Pierre (2024). Endogenous glucocorticoids promote neurogenic heterotopic ossification after spinal cord injury and glucocorticoid receptor antagonist treatment prevents their development. 2024 Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), Toronto, ON, Canada, 27-30 September 2024. Cary, NC, United States: Oxford University Press. doi: 10.1093/jbmr/zjae183
2023
Journal Article
Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development
Salga, Marjorie, Samuel, Selwin G., Tseng, Hsu‐Wen, Gatin, Laure, Girard, Dorothée, Rival, Bastien, Barbier, Valerie, Bisht, Kavita, Shatunova, Svetlana, Debaud, Charlotte, Winkler, Ingrid G., Paquereau, Julie, Dinh, Aurélien, Genêt, Guillaume, Kerever, Sébastien, Abback, Paer‐Sélim, Banzet, Sébastien, Genêt, François, Lévesque, Jean‐Pierre and Alexander, Kylie A. (2023). Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development. Journal of Bone and Mineral Research, 38 (11), 1-18. doi: 10.1002/jbmr.4905
2023
Conference Publication
Gut microflora does not contribute to Neurogenic Heterotopic Ossification after SCI
Samuel, Selwin, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie and Levesque, Jean-Pierre (2023). Gut microflora does not contribute to Neurogenic Heterotopic Ossification after SCI. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX USA, 9-12 September 2022. Cary, NC USA: Oxford University Press.
2023
Conference Publication
Pathogen-associated molecular patterns exacerbate neurogenic heterotopic ossifications after spinal cord injury
Samuel, Selwin, Salga, Marjorie, Tseng, Hsu-Wen, Fleming, Whitney, Genet, Francois, Alexander, Kylie and Levesque, Jean-Pierre (2023). Pathogen-associated molecular patterns exacerbate neurogenic heterotopic ossifications after spinal cord injury. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX USA, 9-12 September 2022. Cary, NC USA: Oxford University Press.
2022
Journal Article
Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors
Gartlan, Kate H., Jaiswal, Jagdish K., Bull, Matthew R., Akhlaghi, Hedieh, Sutton, Vivien R., Alexander, Kylie A., Chang, Karshing, Hill, Geoffrey R., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Trapani, Joseph A., Charman, Susan A., Spicer, Julie A. and Jamieson, Stephen M. F. (2022). Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors. ACS Pharmacology and Translational Science, 5 (6), 429-439. doi: 10.1021/acsptsci.2c00009
2022
Journal Article
Inflammasomes and the IL-1 family in bone homeostasis and disease
Tseng, Hsu-Wen, Samuel, Selwin Gabriel, Schroder, Kate, Lévesque, Jean-Pierre and Alexander, Kylie A (2022). Inflammasomes and the IL-1 family in bone homeostasis and disease. Current Osteoporosis Reports, 20 (3), 170-185. doi: 10.1007/s11914-022-00729-8
2022
Journal Article
Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification
Tseng, Hsu‐Wen, Kulina, Irina, Girard, Dorothée, Gueguen, Jules, Vaquette, Cedryck, Salga, Marjorie, Fleming, Whitney, Jose, Beulah, Millard, Susan M., Pettit, Allison R., Schroder, Kate, Thomas, Gethin, Wheeler, Lawrie, Genêt, François, Banzet, Sébastien, Alexander, Kylie A. and Levesque, Jean‐Pierre (2022). Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification. Journal of Bone and Mineral Research, 37 (3), 531-546. doi: 10.1002/jbmr.4482
2022
Journal Article
Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles
Tseng, Hsu-Wen, Girard, Dorothée, Alexander, Kylie A., Millard, Susan M., Torossian, Frédéric, Anginot, Adrienne, Fleming, Whitney, Gueguen, Jules, Goriot, Marie-Emmanuelle, Clay, Denis, Jose, Beulah, Nowlan, Bianca, Pettit, Allison R., Salga, Marjorie, Genêt, François, Bousse-Kerdilès, Marie-Caroline Le, Banzet, Sébastien and Lévesque, Jean-Pierre (2022). Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone Research, 10 (1) 22, 22. doi: 10.1038/s41413-022-00188-y
2022
Journal Article
Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injury
Alexander, Kylie A., Tseng, Hsu-Wen, Kulina, Irina, Fleming, Whitney, Vaquette, Cedryck, Genêt, François, Ruitenberg, Marc J. and Lévesque, Jean-Pierre (2022). Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injury. Neurotrauma Reports, 3 (1), 87-96. doi: 10.1089/neur.2021.0072
2021
Journal Article
Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization
Bisht, Kavita, McGirr, Crystal, Lee, Seo-Youn, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie A., Matsumoto, Taichi, Barbier, Valérie, Sims, Natalie A., Müller-Newen, Gerhard, Winkler, Ingrid G., Bonig, Halvard and Lévesque, Jean-Pierre (2021). Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization. Leukemia, 36 (2), 333-347. doi: 10.1038/s41375-021-01413-z
2021
Journal Article
Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environment
Girard, Dorothée, Torossian, Frédéric, Oberlin, Estelle, Alexander, Kylie A., Gueguen, Jules, Tseng, Hsu-Wen, Genêt, François, Lataillade, Jean-Jacques, Salga, Marjorie, Levesque, Jean-Pierre, Le Bousse-Kerdilès, Marie-Caroline and Banzet, Sébastien (2021). Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environment. Frontiers in Cell and Developmental Biology, 9 611842, 611842. doi: 10.3389/fcell.2021.611842
2020
Journal Article
Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils
Tseng, Hsu‐Wen, Kulina, Irina, Salga, Marjorie, Fleming, Whitney, Vaquette, Cedryck, Genêt, François, Levesque, Jean‐Pierre and Alexander, Kylie A (2020). Neurogenic heterotopic ossifications develop independently of granulocyte‐colony stimulating factor and neutrophils. Journal of Bone and Mineral Research, 35 (11) jbmr.4118, 2242-2251. doi: 10.1002/jbmr.4118
2020
Journal Article
When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification
Alexander, Kylie A., Tseng, Hsu-Wen, Salga, Marjorie, Genêt, François and Levesque, Jean-Pierre (2020). When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification. Current Osteoporosis Reports, 18 (6), 666-676. doi: 10.1007/s11914-020-00636-w
2019
Journal Article
Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor
Bisht, Kavita, McGirr, Crystal, Alexander, Kylie A, Fleming, Whitney, Sims, Natalie, Newen, Gerhard Müller-, Winkler, Ingrid G and Levesque, Jean-Pierre (2019). Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor. Blood, 134 (Supplement_1), 4469-4469. doi: 10.1182/blood-2019-127431
Supervision
Availability
- Dr Kylie Alexander is:
- Available for supervision
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Supervision history
Completed supervision
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2023
Doctor Philosophy
Role of infections and gut microflora in the development of neurogenic heterotopic ossifications following spinal cord injury in a mouse model
Associate Advisor
Other advisors: Professor Jean-Pierre Levesque
Media
Enquiries
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