Overview
Availability
- Dr Kylie Alexander is:
- Available for supervision
Qualifications
- Bachelor, Griffith University
- Doctor of Philosophy, The University of Queensland
Research interests
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Neurogenic heterotopic ossification
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Macrophage biology and inflammation
Works
Search Professor Kylie Alexander’s works on UQ eSpace
2012
Conference Publication
Promoting Regulation Via the Inhibition of DNAM-1 After Transplantation
Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Leveque, Lucie, Chan, Christopher J., Robb, Renee J., Markey, Kate A., Alexander, Kylie A., Varelias, Antiopi, Clouston, Andrew D., MacDonald, Kelli P. A., Smyth, Mark J. and Hill, Geoffrey R. (2012). Promoting Regulation Via the Inhibition of DNAM-1 After Transplantation. 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 08-11, 2012. WASHINGTON: AMER SOC HEMATOLOGY.
2012
Journal Article
β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice
Ruutu, Merja, Thomas, Gethin, Steck, Roland, Degli-Esposti, Mariapia A., Zinkernagel, Martin S., Alexander, Kylie, Velasco, Jared, Strutton, Geoffrey, Tran, Ai, Benham, Helen, Rehaume, Linda, Wilson, Robert J., Kikly, Kristine, Davies, Julian, Pettit, Allison R., Brown, Matthew A., McGuckin, Michael A. and Thomas, Ranjeny (2012). β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice. Arthritis and Rheumatism, 64 (7), 2211-2222. doi: 10.1002/art.34423
2012
Journal Article
Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation
Robb, R.J., Lineburg, K.E., Kuns, R.D., Wilson, Y.A., Raffelt, N.C., Olver, S.D., Varelias, A., Alexander, K.A., Teal, B.E., Sparwasser, T., Hammerling, G.J., Markey, K.A., Koyama, M., Clouston, A.D., Engwerda, C.R., Hill, G.R. and MacDonald, K.P.A. (2012). Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation. Blood, 119 (24), 5898-5908. doi: 10.1182/blood-2011-12-396119
2012
Journal Article
Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development
Lane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L. and Williams, David A. (2012). Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood, 119 (3), 736-744. doi: 10.1182/blood-2011-07-368753
2011
Journal Article
Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model
Alexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354
2011
Conference Publication
B Cells Do Not Influence Intramembranous Bone Modelling in Vivo
Pettit, A. R., Kaur, S., Alexander, K. A., MacDonald, K. P. A. and Raggatt, L. J. (2011). B Cells Do Not Influence Intramembranous Bone Modelling in Vivo. IOF Regionals 2nd Asia-Pacific Osteoporosis and Bone Meeting / ANZBMS Annual Scientific Meeting held with the JSBMR, Gold Coast, QLD Australia, 4-8 September 2011. London, United Kingdom: Springer.
2010
Journal Article
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
Winkler, Ingrid G., Sims, Natalie A., Pettit, Allison R., Barbier, Valérie, Nowlan, Bianca, Helwani, Falak, Poulton, Ingrid J., van Rooijen, Nico van, Alexander, Kylie A., Raggatt, Liza J. and Levesque, Jean-Pierre (2010). Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood, 116 (23), 4815-4828. doi: 10.1182/blood-2009-11-253534
2010
Other Outputs
Osteal macrophages (osteomacs) are pivotal for intramembranous bone formation in vivo: Osteomacs facilitate osteoblast maintenance in vivo and enhance osteoblast-mediated bone deposition in a murine model of bone healing
Alexander, Kylie (2010). Osteal macrophages (osteomacs) are pivotal for intramembranous bone formation in vivo: Osteomacs facilitate osteoblast maintenance in vivo and enhance osteoblast-mediated bone deposition in a murine model of bone healing. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.
2009
Conference Publication
Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization
Pettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082
2009
Conference Publication
Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing
Alexander, K. A., Raggatt, L. J., Chang, M. K., Maylin, E. R., Muller, R., Kohler, T., Wu, A. C. K., Hume, D. A. and Pettit, A. R. (2009). Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, NSW, Australia, 21-25 March 2009. United States: Elsevier. doi: 10.1016/j.bone.2009.01.076
2009
Conference Publication
Osteomacs are Critical for Optimal Intramembranous Bone Formation in a Tibial Defect Model of Bone Healing
Alexander, K. A., Raggatt, L., Chang, M., Maylin, E., Muller, R., Kohler, T., Wu, A., Hume, D. and Pettit, A. (2009). Osteomacs are Critical for Optimal Intramembranous Bone Formation in a Tibial Defect Model of Bone Healing. Australian Society of Bone and Mineral Research (ASBMR) 31st Annual Meeting, Denver, Colorado, USA, 11-15 September, 2009. United States: American Society for Bone and Mineral Research.
2009
Conference Publication
Osteomacs: Osteoclast Precursors During Inflammatory Bone Disease but Regulators of Physiologic Bone Remodeling
Raggatt, L., Chang, M., Alexander, K., Maylin, E., Walsh, N., Gravallese, E., Hume, D. and Pettit, A. (2009). Osteomacs: Osteoclast Precursors During Inflammatory Bone Disease but Regulators of Physiologic Bone Remodeling. Australian Society of Bone and Mineral Research (ASBMR) 31st Annual Meeting, Denver, CO, United States, 11-15 September, 2009. United States: American Society for Bone and Mineral Research.
2009
Conference Publication
Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling
Raggatt, L. J., Chang, M. K., Alexander, K. A., Maylin, E. R., Walsh, N. C., Gravallese, E. M., Hume, D. A. and Pettit, A. R. (2009). Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, Australia, 21-25 March, 2009. New York: Elsevier Science. doi: 10.1016/j.bone.2009.01.300
2008
Journal Article
Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo
Chang, Ming K., Raggatt, Liza-Jane, Alexander, Kylie A., Kuliwaba, Julia S., Fazzalari, Nicola L., Schroder, Kate, Maylin, Erin R., Ripoll, Vera M, Hume, David A. and Pettit, Allison R. (2008). Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo. The Journal of Immunology, 181 (2), 1232-1244. doi: 10.4049/jimmunol.181.2.1232
2008
Journal Article
Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice
Ovchinnikov, Dmitry A., van Zuylen, Wendy J. M., DeBats, Claire E. E., Alexander, Kylie A., Kellie, Stuart and Hume, David A. (2008). Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice. Journal of Leukocyte Biology, 83 (2), 430-433. doi: 10.1189/jlb.0807585
2008
Conference Publication
Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation
Chang, M. K., Pettit, A. R., Schroder, K., Ripoll, V. M., Alexander, K. A., Hume, D. A. and Raggatt, L. (2008). Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation. ECTS 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, NY, U.S.A.: Springer New York. doi: 10.1007/s00223-008-9118-5
2008
Conference Publication
Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralization
Alexander, K. A., Chang, M. K., Hume, D. A., Pettit, A. R., Raggatt, L., Ripoli, V. M. and Schroder, K. (2008). Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralization. 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, USA: Springer. doi: 10.1007/s00223-008-9118-5
2007
Conference Publication
Osteal Macrophages: Novel regulators of Bone Formation
Raggatt, L. J., Chang, M. K., Alexander, K. A., Kuiliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal Macrophages: Novel regulators of Bone Formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, 16th -19th September, 2007. Washington, D.C., United States: American Society for Bone and Mineral Research.
2007
Conference Publication
The endosteal bone niche contains macrophages that regulate osteoblast function
Pettit, A. R., Chang, M. K., Alexander, K. A., Wu, A. C., Hume, D. A. and Raggatt, L. J. (2007). The endosteal bone niche contains macrophages that regulate osteoblast function. 17th Scientific Meeting of the International Bone & Mineral Society, Montreal, Canada, 24-29 June 2007. New York: Elsevier Science. doi: 10.1016/j.bone.2007.04.166
2007
Conference Publication
Osteal macrophages: Novel regulators of bone formation
Raggatt, L. J., Alexander, K. A., Kuliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal macrophages: Novel regulators of bone formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, United States, 16-19 September 2007.
Funding
Past funding
Supervision
Availability
- Dr Kylie Alexander is:
- Available for supervision
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Supervision history
Completed supervision
-
2023
Doctor Philosophy
Role of infections and gut microflora in the development of neurogenic heterotopic ossifications following spinal cord injury in a mouse model
Associate Advisor
Other advisors: Professor Jean-Pierre Levesque
Media
Enquiries
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