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Honorary Professor

Jean-Pierre Levesque

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Overview

Availability

Honorary Professor Jean-Pierre Levesque is:
Available for supervision

Works

Search Professor Jean-Pierre Levesque’s works on UQ eSpace

222 works between 1985 and 2025

121 - 140 of 222 works

2011

Conference Publication

Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF

Forristal, Catherine, Nowlan, Bianca, Barbier, Valerie, McCarthy, Domenica, Walkinshaw, Gail, Winkler, Ingrid G. and Levesque, Jean-Pierre (2011). Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.

Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF

2011

Conference Publication

Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow

Levesque, Jean-Pierre, Barbier, Valerie, Nowlan, Bianca, McCarhty, Domenica and Winkler, Ingrid G. (2011). Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.

Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow

2011

Journal Article

Mobilisation strategies for normal and malignant cells

To, L. Bik, Levesque, Jean-Pierre, Herbert, Kirsten E., Winkler, Ingrid G., Bendall, Linda J., Hiwase, Devendra K., Antonenas, Vicki, Rice, Alison M., Gottlieb, David, Mills, Anthony K., Rasko, John E. J., Larsen, Stephen, Beligaswatte, Ashanka, Nilsson, Susan K., Cooney, Julian P., Cambareri, Antony C. and Lewis, Ian D. (2011). Mobilisation strategies for normal and malignant cells. Pathology, 43 (6), 547-565. doi: 10.1097/PAT.0b013e32834a9eb8

Mobilisation strategies for normal and malignant cells

2011

Journal Article

How I treat patients who mobilize hematopoietic stem cells poorly

To, L. Bik, Levesque, Jean-Pierre and Herbert, Kirsten E. (2011). How I treat patients who mobilize hematopoietic stem cells poorly. Blood, 118 (17), 4530-4540. doi: 10.1182/blood-2011-06-318220

How I treat patients who mobilize hematopoietic stem cells poorly

2011

Journal Article

How we mobilize haemopoietic stem cells

Herbert, K.E., Levesque, J.P., Mills, A.K., Gottlieb, D.J., Cooney, J., Szer, J., Rasko, J. and To, L.B. (2011). How we mobilize haemopoietic stem cells. Internal Medicine Journal, 41 (8), 588-594. doi: 10.1111/j.1445-5994.2011.02544.x

How we mobilize haemopoietic stem cells

2011

Journal Article

Hierarchy of immature hematopoietic cells related to blood flow and niche

Levesque, Jean-Pierre and Winkler, Ingrid G. (2011). Hierarchy of immature hematopoietic cells related to blood flow and niche. Current Opinion in Hematology, 18 (4), 220-225. doi: 10.1097/MOH.0b013e3283475fe7

Hierarchy of immature hematopoietic cells related to blood flow and niche

2011

Conference Publication

Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis

Levesque, Jean-Pierre, Bendall, Linda J., Pettit, Allison R., Raggatt, Liza, Jacobsen, Rebecca, Barbier, Valarie, Nowlan, Bianca, Shen, Yi Shen, Sims, Natalie A. and Winkler, Ingrid G. (2011). Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.

Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis

2010

Journal Article

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Winkler, Ingrid G., Sims, Natalie A., Pettit, Allison R., Barbier, Valérie, Nowlan, Bianca, Helwani, Falak, Poulton, Ingrid J., van Rooijen, Nico van, Alexander, Kylie A., Raggatt, Liza J. and Levesque, Jean-Pierre (2010). Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood, 116 (23), 4815-4828. doi: 10.1182/blood-2009-11-253534

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

2010

Journal Article

The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization

Lévesque, J.-P., Helwani, F. M. and Winkler, I. G. (2010). The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization. Leukemia, 24 (12), 1979-1992. doi: 10.1038/leu.2010.214

The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization

2010

Journal Article

Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo

Shen, Yi, Winkler, Ingrid G., Barbier, Valerie, Sims, Natalie A., Hendy, Jean and Lévesque, Jean-Pierre (2010). Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo. PLoS One, 5 (9) e13086, e13086-1-e13086-13. doi: 10.1371/journal.pone.0013086

Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo

2010

Conference Publication

A molecular profile of the hematopoietic stem cell niche at the endosteum

Helwani, F., Winkler, I., Price, G. and Levesque, J. P. (2010). A molecular profile of the hematopoietic stem cell niche at the endosteum. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier.

A molecular profile of the hematopoietic stem cell niche at the endosteum

2010

Conference Publication

The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis

Shen, Y., Barbier, V., Winkler, I., Sims, N., Hendy, J. and Levesque, J. P. (2010). The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier.

The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis

2010

Journal Article

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

Winkler, Ingrid G., Barbier, Valérie, Wadley, Robert, Zannettino, Andrew C. W., Williams, Sharon and Lévesque, Jean-Pierre (2010). Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches. Blood, 116 (3), 375-385. doi: 10.1182/blood-2009-07-233437

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

2010

Conference Publication

DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS

Jacobsen, RN, Levesque, JP, Barbier, V, Raggatt, LJ and Pettit, AR (2010). DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS. 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Melbourne AUSTRALIA, SEP 15-18, 2010. NEW YORK: ELSEVIER SCIENCE INC.

DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS

2009

Journal Article

38th annual meeting of the international society of experimental hematology

Levesque, Jean-Pierre and Winkler, Ingrid G. (2009). 38th annual meeting of the international society of experimental hematology. Expert Review of Hematology, 2 (6), 645-647. doi: 10.1586/ehm.09.61

38th annual meeting of the international society of experimental hematology

2009

Conference Publication

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance

Winkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Smith, Theodore, Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2009). Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology.

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance

2009

Conference Publication

Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance

Winkler, I. G., Levesque, J. P., Barbier, V. and Nowlan, B. (2009). Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier.

Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance

2009

Conference Publication

Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood

Levesque, J. P., Barbier, V., Wadley, R. and Winkler, I. G. (2009). Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier.

Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood

2009

Conference Publication

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

Pettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

2009

Conference Publication

Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy

Levesque, J. P., Raggatt, L. J., Pettit, A. R., Sims, N. A., Bendall, L. J. and Helwani, F. (2009). Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. NEW YORK: ELSEVIER SCIENCE INC.

Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy

Funding

Current funding

  • 2025 - 2028
    Mechanisms and first prophylactic treatments of neurogenic heterotopic ossifications
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2020 - 2024
    Discovering the mechanisms of neurogenic heterotopic ossifications following spinal cord injuries
    NHMRC IDEAS Grants
    Open grant
  • 2018 - 2020
    Colony-stimulating factor 1 receptor tyrosine kinase, a new target to treat acute myeloid leukemia
    Cancer Council Queensland
    Open grant
  • 2018 - 2020
    Increasing haematopoietic stem cell mobilisation by targeting a novel niche factor
    NHMRC Project Grant
    Open grant
  • 2018 - 2022
    Stem cell niches: Biology and therapeutic applications
    NHMRC Research Fellowship
    Open grant
  • 2017 - 2020
    Mechanisms by which Endothelial Selectins regulate Normal and Malignant Stem Cell fate
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Recipient bone marrow macrophages contribute to haematopoietic stem cell transplantation success
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Why macrophages promote heterotopic ossifications following spinal cord injuries
    NHMRC Project Grant
    Open grant
  • 2015 - 2019
    Mechanisms and Treatments of Heterotopic Ossification following Spinal Cord Injuries
    United States Congressionally Directed Medical Research Programs - Spinal Cord Injury Research Program
    Open grant
  • 2015 - 2017
    A preclinical humanized chimeric model to investigate novel therapeutic strategies against breast cancer bone metastasis (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2015 - 2018
    Haematopoietic Stem Cell glycome regulates outcome of niche interactions
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Targeting the hypoxia sensing pathway to improve hematopoietic stem cell mobilisation and transplantation
    NHMRC Project Grant
    Open grant
  • 2014 - 2015
    The role of macrophages in facilitating hematopoietic stem cell engraftment and reconstitution
    Cancer Council Queensland
    Open grant
  • 2013 - 2017
    NHMRC Research Fellowship: How does the bone marrow regulate normal blood formation and leukaemia progression.
    NHMRC Research Fellowship
    Open grant
  • 2013 - 2016
    Role of bone marrow cells in leukemia progression and resistance to chemotherapy
    NHMRC Project Grant
    Open grant
  • 2011 - 2012
    Comprehensive cell imaging facility (ARC LIEF Grant administered by QUT)
    ARC LIEF Collaborating/Partner Organisation Contributions
    Open grant
  • 2007 - 2012
    Interaction between PTH and Y2 bone anabolic pathways
    NHMRC Project Grant
    Open grant

Supervision

Availability

Honorary Professor Jean-Pierre Levesque is:
Available for supervision

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Supervision history

Completed supervision

Media

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