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2014 Journal Article Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injuryDe Hoog, Vince C., Timmers, Leo, Van Duijvenvoorde, Amerik, De Jager, Saskia C. A., Van Middelaar, Ben J., Smeets, Mirjam B., Woodruff, Trent M., Doevendans, Pieter A., Pasterkamp, Gerard, Hack, C. Erik and De Kleijn, Dominique P. V. (2014). Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury. Cardiovascular Research, 103 (4), 521-529. doi: 10.1093/cvr/cvu153 |
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2013 Journal Article Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosisLee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119 |
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2013 Journal Article A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root gangliaSmith, Maree T., Woodruff, Trent M., Wyse, Bruce D., Muralidharan, Arjun and Walther, Thomas (2013). A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Medicine, 14 (10), 1557-1568. doi: 10.1111/pme.12157 |
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2013 Journal Article Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsiaDenny, Kerina J., Coulthard, Liam G., Finnell, Richard H., Callaway, Leonie K., Taylor, Stephen M. and Woodruff, Trent M. (2013). Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. Journal of Reproductive Immunology, 97 (2), 211-216. doi: 10.1016/j.jri.2012.11.006 |
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2013 Journal Article C5a receptor signaling prevents folate deficiency-induced neural tube defects in miceDenny, Kerina J., Coulthard, Liam G., Jeanes, Angela, Lisgo, Steven, Simmons, David G., Callaway, Leonie K., Wlodarczyk, Bogdan, Finnell, Richard H., Woodruff, Trent M. and Taylor, Stephen M. (2013). C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. Journal of Immunology, 190 (7), 3493-3499. doi: 10.4049/jimmunol.1203072 |
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2013 Journal Article C5L2: a controversial receptor of complement anaphylatoxin, C5aLi, Rui, Coulthard, Liam G., Wu, M. C. L., Taylor, Stephen M. and Woodruff, Trent M. (2013). C5L2: a controversial receptor of complement anaphylatoxin, C5a. FASEB Journal, 27 (3), 855-864. doi: 10.1096/fj.12-220509 |
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2013 Journal Article Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft diseasede Vries, Margreet R., Wezel, Anouk, Schepers, Abbey, van Santbrink, Peter J., Woodruff, Trent M., Niessen, Hans W. M., Hamming, Jaap F., Kuiper, Johan, Bot, Ilze and Quax, Paul H. A. (2013). Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease. Cardiovascular Research, 97 (2), 311-320. doi: 10.1093/cvr/cvs312 |
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2013 Journal Article The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10Jain, U., Woodruff, T. M. and Stadnyk, A. W. (2013). The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10. British Journal of Pharmacology, 168 (2), 488-501. doi: 10.1111/j.1476-5381.2012.02183.x |
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2013 Journal Article Complement in pregnancy: a delicate balanceDenny, Kerina J., Woodruff, Trent M., Taylor, Stephen M. and Callaway, Leonie K. (2013). Complement in pregnancy: a delicate balance. American Journal of Reproductive Immunology, 69 (1), 3-11. doi: 10.1111/aji.12000 |
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2013 Journal Article Neural tube defects, folate, and immune modulationDenny, Kerina J., Jeanes, Angela, Fathe, Kristin, Finnell, Richard H., Taylor, Stephen M. and Woodruff, Trent M. (2013). Neural tube defects, folate, and immune modulation. Birth Defects Research Part A - Clinical and Molecular Teratology, 97 (9), 602-609. doi: 10.1002/bdra.23177 |
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2013 Journal Article Neutrophils-A key component of ischemia-reperfusion injurySchofield, Zoe Victoria, Woodruff, Trent Martin, Halai, Reena, Wu, Mike Chia-Lun and Cooper, Matthew Allister (2013). Neutrophils-A key component of ischemia-reperfusion injury. Shock, 40 (6), 463-470. doi: 10.1097/SHK.0000000000000044 |
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2012 Journal Article Eph/Ephrin signaling in injury and inflammationCoulthard, Mark G., Morgan, Michael, Woodruff, Trent M., Arumugam, Thiruma V., Taylor, Stephen M., Carpenter, Todd C., Martin Lackmann, and Boyd, Andrew W. (2012). Eph/Ephrin signaling in injury and inflammation. American Journal of Pathology, 181 (5), 1493-1503. doi: 10.1016/j.ajpath.2012.06.043 |
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2012 Journal Article Generation of complement component C5a by ischemic neurons promotes neuronal apoptosisPavlovski, Dale, Thundyil, John, Monk, Peter N., Wetsel, Rick A., Taylor, Stephen M. and Woodruff, Trent M. (2012). Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis. The FASEB Journal, 26 (9), 3680-3690. doi: 10.1096/fj.11-202382 |
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2012 Journal Article Complement activation in the injured central nervous system: Another dual-edged sword?Brennan, Faith H., Anderson, Aileen J., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012). Complement activation in the injured central nervous system: Another dual-edged sword?. Journal of Neuroinflammation, 9 (1) 137, 137. doi: 10.1186/1742-2094-9-137 |
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2012 Journal Article Complement C5a regulates prolabor mediators in human placentaLappas, Martha, Woodruff, Trent M., Taylor, Stephen M. and Permezel, Michael (2012). Complement C5a regulates prolabor mediators in human placenta. Biology of Reproduction, 86 (6) 190, 190.1-190.9. doi: 10.1095/biolreprod.111.098475 |
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2012 Journal Article De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validationBellows-Peterson, Meghan L., Fung, Ho Ki, Floudas, Christodoulos A., Kieslich, Chris A., Zhang, Li, Morikis, Dimitrios, Wareham, Kathryn J., Monk, Peter N., Hawksworth, Owen A. and Woodruff, Trent M. (2012). De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validation. Journal of Medicinal Chemistry, 55 (9), 4159-4168. doi: 10.1021/jm201609k |
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2011 Journal Article Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive ratsIyer, Abishek, Woodruff, Trent M., Wu, Mike C. L., Stylianou, Con, Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and Brown, Lindsay (2011). Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats. Journal of Cardiovascular Pharmacology, 58 (5), 479-486. doi: 10.1097/FJC.0b013e31822a7a09 |
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2011 Journal Article Inhibiting the C5-C5a receptor axisWoodruff, Trent M., Nandakumar, Kutty S. and Tedesco, Francesco (2011). Inhibiting the C5-C5a receptor axis. Molecular Immunology, 48 (14), 1631-1642. doi: 10.1016/j.molimm.2011.04.014 |
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2011 Journal Article Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in ratsBreivik, T., Gundersen, Y., Gjermo, P., Taylor, S. M., Woodruff, T. M. and Opstad, P. K. (2011). Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats. Journal of Periodontal Research, 46 (6), 643-647. doi: 10.1111/j.1600-0765.2011.01383.x |
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2011 Journal Article Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) miceManthey, Helga D., Thomas, Anita C., Shiels, Ian A., Zernecke, Alma, Woodruff, Trent M., Rolfe, Barbara and Taylor, Stephen M. (2011). Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice. FASEB Journal, 25 (7), 2447-2455. doi: 10.1096/fj.10-174284 |
